!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!drug_name	Doxycycline
!smiles	CC1C2C(C3C(C(=O)C(=C(N)O)C(=O)C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)N(C)C)O
!drugbank_id	DB00254
!pubchem_cid	5281011
!cell_type	RT112 cancer cell line (FGFR3 knocked down with shRNA 4-1)
!organism	human
!end_metadata
FABP5	-0.105626
NAP1L5	-0.100450
NDN	0.100338
SERPINH1	-0.088636
KDELC2	-0.082582
AOC1	0.081250
EPHX4	0.078963
LRRN1	-0.071349
PYCARD	-0.068415
H19	0.066394
PLAGL1	-0.061147
MDK	-0.060673
PLSCR4	-0.058438
DAPL1	0.055811
HCLS1	-0.052513
PCK1	0.050647
PCDHB2	0.048523
CD109	-0.048268
DCP1B	0.047748
HDX	-0.047254
PVRL3	-0.046685
CEACAM6	0.046092
UBE2E2	-0.046034
BEX4	-0.045693
TP53	-0.045656
LGALS1	-0.043669
SLC6A14	0.042166
ARMCX3	-0.041810
C8orf4	0.039570
TMEM45A	-0.038724
FAM221A	0.038516
MALAT1	0.038233
RYR1	-0.037937
PDGFD	-0.037131
ROBO1	-0.036857
GALM	0.036082
ANKRD6	-0.035848
JSRP1	0.035650
IFI6	-0.034894
BASP1	-0.034805
LGR5	-0.034533
CLIC3	-0.034390
TRIP6	-0.034244
GABBR2	-0.033748
COX3	0.032886
OLR1	-0.032529
DPEP2	-0.032239
CYP2F1	-0.032228
ZNF883	-0.031936
ANXA3	-0.031393
BDH2	-0.030789
ZDHHC8P1	-0.030643
GBP4	0.030425
KRT5	-0.030269
HAMP	0.030069
BEX2	-0.030061
CP	0.029867
F5	0.029730
ARMCX6	-0.029533
TMEM255A	-0.029485
SPINK4	-0.029374
DSPP	0.029374
OXGR1	-0.028962
TRPC1	-0.028781
HEPACAM2	0.028305
WLS	-0.028206
GAS1	-0.027670
WIPF1	-0.027507
TCEAL8	-0.027484
MEIS3P1	0.027323
ANKS1A	0.027186
SLC25A21-AS1	0.027139
SEMA3A	0.027115
MT1X	-0.027045
ID2	-0.026850
PLEKHS1	0.026840
FRK	0.026721
LOC149401	0.026706
MAGEA6	0.026615
WNT5A	0.026525
PTPRR	0.026487
ZBED2	-0.026307
COL5A1	-0.026237
NRAS	-0.026211
LIPG	-0.026208
LINC01003	0.026190
DPY19L2	-0.026139
SMKR1	-0.026139
HPGD	0.026132
GPC4	-0.026018
ZNF431	0.025957
MED18	0.025846
NAP1L2	0.025748
AGBL2	-0.025599
PLA2G10	0.025555
MT1H	-0.025457
LOC100134445	0.025449
SHISA2	-0.025316
TCF7L1	-0.025312
SUSD5	-0.025275
NT5E	0.024950
GNG4	0.024902
LOC101927769	-0.024802
VENTX	-0.024680
PPP1R14A	-0.024653
FAM129A	-0.024524
FRAS1	-0.024422
B9D1	-0.024214
NME4	-0.024184
CD72	-0.024017
BAALC	0.023929
CLDN8	0.023903
GAN	0.023900
MACC1	0.023794
ZNF610	-0.023768
DPP10-AS1	-0.023736
MYL9	-0.023663
CHST2	-0.023522
AQP5	-0.023457
RRAGD	-0.023387
LOC653602	0.023304
ZFP3	-0.023262
AKR1C3	0.023183
DMBT1	0.023163
TMSB15B	-0.023157
LOC643549	-0.023147
MARVELD1	-0.023085
NFKBIZ	0.023069
MAP2	-0.022933
GJA1	0.022909
GUSBP5	-0.022871
MT2A	-0.022848
ALDOAP2	0.022734
CYP3A5	0.022663
MYADM	-0.022621
PCSK9	-0.022600
ANKRD36	0.022564
PSCA	0.022558
DSG1	-0.022536
ACN9	0.022531
CAPNS2	0.022327
CYS1	-0.022111
YEATS4	0.022106
PLA2G4A	0.021896
TMEM139	-0.021871
GSAP	0.021865
C1orf220	-0.021859
TMEM52B	-0.021828
LHFP	-0.021747
MATN3	-0.021708
CNN3	-0.021703
MT1HL1	-0.021702
LOC100129406	0.021699
LRRC63	-0.021694
PLAT	0.021693
DPH6-AS1	-0.021593
FADS1	-0.021561
LOC101927657	-0.021512
GABRP	-0.021511
TNNI3	-0.021509
OSR1	-0.021495
CCDC144B	0.021365
FGFBP2	-0.021245
OXT	-0.021191
FSIP1	-0.021183
NEBL-AS1	-0.021145
NETO2	0.021077
HERC5	-0.020931
PMS2P9	0.020916
LOC439938	0.020886
KIF28P	0.020856
HSPB9	0.020821
C3orf33	-0.020821
DSCAML1	-0.020710
SLC20A1	0.020673
IFI30	-0.020670
UCP2	-0.020658
BTBD11	-0.020650
PID1	-0.020630
BEAN1	-0.020603
HTR2C	-0.020577
GSDMD	-0.020532
EPSTI1	0.020486
DYRK4	-0.020422
SLC16A1	-0.020420
RBM34	-0.020415
ZNF750	0.020404
PODXL2	-0.020378
SYBU	0.020374
BFSP2	-0.020330
FGFR3	-0.020286
ID3	-0.020253
BMP2	-0.020213
ELMO3	0.020182
FAM229B	-0.020162
EN1	-0.020115
C16orf54	-0.020108
C18orf42	-0.020099
CD68	0.020092
SECISBP2L	0.020079
OR6A2	-0.020074
TRMT13	0.020044
LINC01432	-0.020030
SLC25A21	-0.020011
MGC12488	0.019989
LOC400965	-0.019935
LECT2	-0.019915
LOC101928940	-0.019892
LY6D	-0.019887
DRD4	-0.019830
COL4A2	-0.019814
MT1F	-0.019809
GALNT4	0.019787
CHAC2	0.019782
LOC100507630	0.019772
EMB	0.019755
HMX2	-0.019748
C20orf85	-0.019707
F13A1	-0.019694
CERCAM	-0.019671
LOC101926944	-0.019654
ADRA2C	0.019614
PGLYRP3	-0.019600
CYP1A1	0.019591
RHOXF1	-0.019574
PRPF38B	0.019527
DNAJB8	-0.019512
TSPAN8	-0.019435
PLBD1	0.019432
POTEKP	-0.019421
GPR144	0.019414
PRAC1	0.019409
CDK5R1	-0.019393
C1orf87	-0.019392
AASS	0.019385
CCZ1B	0.019317
LINC01289	-0.019304
EGFLAM-AS4	-0.019282
PRSS23	-0.019277
PAXIP1-AS1	0.019275
GLRB	-0.019274
LOC101928043	-0.019252
C8orf48	-0.019240
CMTM3	-0.019233
MAP9	0.019151
IL27	-0.019124
ANKRD36B	0.019114
SGPP1	0.019087
LINC00572	-0.019083
GK5	0.019073
LIPE	-0.019055
LOC100272216	0.019039
PIK3C2G	-0.019020
ZNF861P	-0.019013
FAM27D1	-0.018988
BOLA3-AS1	-0.018950
MMP10	-0.018937
THBS1	-0.018931
KRT20	-0.018930
DMKN	-0.018926
LINC00470	-0.018919
DACT1	-0.018909
C17orf75	0.018865
LOC101927588	-0.018864
WDR78	-0.018831
C2orf15	0.018818
GAS2	0.018775
RCAN2	-0.018760
TMEM173	-0.018734
MAP1LC3C	0.018725
GADD45A	0.018695
CPVL	-0.018652
CTSO	-0.018648
A1BG-AS1	0.018647
FLJ35700	-0.018645
LOC101928446	-0.018600
FGF10	-0.018591
LOC100506235	-0.018565
AGPAT9	0.018552
TTTY11	-0.018540
EPB41L2	-0.018538
LOC283674	-0.018533
SAMD9	0.018522
LOC652993	0.018515
ID4	-0.018480
C8orf31	-0.018462
KCNIP1	-0.018461
NOVA1	-0.018457
P2RY4	-0.018453
TOLLIP-AS1	0.018442
PDZK1	-0.018424
SMAGP	0.018360
RUNDC3B	-0.018334
FGD5	-0.018329
SKP2	-0.018327
ANKRD20A9P	0.018305
PNPLA7	-0.018289
CYP1B1-AS1	-0.018278
SLC27A2	0.018269
CNTD2	-0.018255
TJP3	0.018237
HIST1H4F	-0.018203
HIST1H2BG	0.018195
MLC1	-0.018188
CLEC1B	0.018171
ZNF695	-0.018168
FOXO6	0.018167
IGFBP6	-0.018144
ATAD3C	0.018128
LINC01197	-0.018103
PTX3	-0.018062
PTPN13	0.018059
PIGW	0.018053
SCD	-0.018050
CYCS	0.018044
FAM110C	0.018043
LOC101927948	-0.018032
CHUK	0.018024
SNCAIP	-0.017983
LOC100507468	-0.017981
SHE	-0.017949
VN1R2	-0.017927
EVA1A	-0.017918
LINC00969	0.017908
SLC14A1	0.017906
TM7SF2	-0.017888
SLC16A9	-0.017882
MANSC1	0.017862
FAM188B	-0.017848
PTRF	-0.017831
CYP4F3	0.017829
MAST1	-0.017812
PDSS2	0.017775
CALD1	-0.017754
C5AR1	0.017751
ZSCAN31	0.017747
RIIAD1	-0.017705
SYTL5	0.017692
MIR22HG	0.017691
JPX	0.017668
ABHD2	0.017667
C1orf27	0.017652
CCDC186	0.017642
CAPSL	-0.017627
LOC100128727	-0.017619
LOC101927003	-0.017611
ATP1B1	0.017597
GRIPAP1	0.017592
FABP4	0.017577
ZNF83	0.017576
NKX6-1	0.017556
NPW	-0.017548
AKT3	-0.017507
LYSMD2	0.017467
IRAK1BP1	0.017463
LKAAEAR1	-0.017445
PSG5	-0.017421
C17orf50	-0.017417
GALNT18	-0.017390
ALX4	-0.017356
LOC284600	0.017344
ID1	-0.017341
LINC01420	0.017330
THOC6	-0.017296
AKT1S1	-0.017289
SLX4IP	0.017278
ECI2	-0.017275
CTGF	-0.017249
ALKBH5	-0.017249
GBP2	0.017243
AGR3	0.017223
LBH	-0.017201
AHR	0.017188
LINC00615	-0.017182
LINC00284	0.017176
FLNA	-0.017173
LOC102606465	-0.017157
PSMD6-AS2	0.017139
TAC4	0.017118
PCDHB5	0.017116
HHLA3	-0.017115
SMAD7	-0.017071
IMPA1	0.017052
TMEM251	0.017043
ZFPM2	-0.017035
SHANK1	-0.017010
AZIN1	0.016974
ARHGEF6	-0.016950
PPP1R14C	0.016948
IFIT1	-0.016939
RND1	-0.016919
ACOXL	0.016872
DVL1	0.016846
BEX5	0.016842
GPR34	-0.016841
DOC2B	-0.016834
ZSCAN29	0.016807
LOC145474	0.016806
PPP5D1	-0.016805
OTUD6B	0.016799
AADACP1	0.016790
GC	-0.016789
CSGALNACT1	-0.016780
LBR	0.016780
PALM2	-0.016724
FKBP1B	0.016708
ARRDC3	0.016707
ANHX	-0.016684
CATSPER1	-0.016657
PCDHB14	0.016646
LOC101926928	-0.016632
ASCL5	-0.016631
ST6GAL2	-0.016629
KIAA1875	-0.016619
MAP4K3	0.016612
SCNN1B	0.016606
RALGAPA2	0.016599
ANKRD20A5P	0.016596
CAB39L	0.016581
CDK2	-0.016570
LOC100507165	-0.016570
KAAG1	0.016557
DGCR7	-0.016532
R3HDML	-0.016513
C9orf40	-0.016505
PVRL3-AS1	0.016497
XRCC2	0.016473
LCORL	0.016460
LOC439911	0.016446
NCF4	0.016440
NDUFA5	0.016428
CBY3	-0.016422
TLCD2	0.016418
RNF128	0.016407
LOC340340	-0.016371
PSAT1	0.016356
BAMBI	-0.016332
RFPL1	-0.016313
GSC	-0.016291
CDH5	0.016272
CBX5	-0.016266
AMIGO2	0.016253
TMTC2	0.016248
SMCR5	0.016241
DGKI	0.016233
LOC100134822	0.016228
TEPP	-0.016208
FRMD4A	0.016199
KLF5	0.016180
FN1	-0.016169
FLJ36848	0.016162
SEC63	-0.016162
TTC32	0.016139
SHPRH	0.016129
CAPN14	0.016123
AMICA1	0.016120
WBSCR27	-0.016104
LOC100132352	0.016102
SMIM3	0.016093
HSPA13	0.016092
CYP2S1	-0.016085
PILRB	0.016081
TRAK2	0.016073
F3	0.016047
LOC101927310	-0.016042
EGFEM1P	0.016025
PLEKHG1	0.016006
POC1B	0.015947
FAM154A	-0.015937
MAP3K5	0.015918
DHX40	0.015918
ASIC3	0.015896
MUC19	-0.015891
ELANE	0.015874
TMEM87B	0.015872
NDP	-0.015870
SRSF11	0.015868
LOC283745	-0.015861
SERPINB4	-0.015859
CKAP2	0.015857
FLJ32154	-0.015853
ZNF165	0.015850
DNAAF2	0.015848
LOC101929384	-0.015847
CENPV	-0.015845
LINC01141	-0.015839
SCGB1D1	-0.015830
SATB2	0.015827
LOC202025	0.015818
PLAU	-0.015815
EPHA7	-0.015809
RXFP2	-0.015808
LOC101927040	-0.015807
PACRG-AS1	-0.015798
CCDC84	0.015761
ACTR3C	0.015759
PROCR	0.015748
PCDHB10	0.015716
TRIM31	0.015709
KLHDC2	0.015707