!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	rat
!drug_name	Phenytoin
!smiles	C1=CC=C(C=C1)C2(C(=O)NC(=O)N2)C3=CC=CC=C3
!drugbank_id	DB00252
!pubchem_cid	1775
!cell_type	brainstem
!organism	rat
!end_metadata
GFAP	-0.219291
NEFH	0.211725
RPL9	0.181094
TTR	0.150231
APOD	-0.125569
NNAT	0.124752
USMG5	0.119829
RPL26	0.116469
COX7A2	0.107031
COPS6	0.105172
RPL37	0.103224
COX7B	0.100310
DBNDD2	-0.086427
RPS17	0.085797
RPS19	0.085681
FABP7	-0.084506
RPS21	0.083141
ATP1A3	0.080764
CHCHD10	0.079101
ACTB	-0.077806
PTGDS	-0.077782
UQCRC1	0.077203
RPS4Y1	0.075105
SLC22A17	0.072268
CLDN11	-0.071645
GABRA1	0.070709
PLEKHB1	-0.070572
RPS8	0.069918
MAG	-0.069828
CNP	-0.069130
UQCR10	0.068997
PCP4	0.068351
GOT1	0.067895
RPS20	0.067801
S100B	-0.066641
GNB2L1	0.066117
RPL17	0.066033
RPS15A	0.064888
CEND1	0.064398
RPL38	0.063150
COX1	-0.063074
PBX3	0.062919
BCAS1	0.062776
RPL13A	0.062755
ND3	0.060632
RPL31	0.060567
ATP5B	0.060304
HSP90AB1	-0.060109
ATP5O	0.059694
NAP1L5	0.059585
SPARCL1	0.059545
ATP5C1	0.059343
LDHB	0.058340
EEF1A2	0.057790
PRKAR1B	0.057016
PKM	0.057002
NTSR2	-0.056857
CHCHD2	0.056320
TIMM8B	0.056263
DNM1	0.055994
PSMC2	0.055935
COX4I1	0.055161
TUBB2A	0.054941
RPS6	0.054813
NDUFB9	0.053984
RPL24	0.053418
RPS11	0.053190
FGF13	-0.053070
ISCU	0.052931
NDRG4	0.052686
APOE	-0.052632
RPS29	-0.052199
CD74	-0.052189
STMN3	0.051109
RPS27A	0.050941
NDN	0.050888
RPS14	0.050653
COX6A1	0.050633
ATP5J2	0.050361
SCG5	0.049856
NDUFB5	0.049081
RPS25	0.048785
KLK6	-0.048763
NAPB	0.048328
RPL23	0.048167
SNAP25	-0.047955
VDAC3	0.047509
ATP5H	0.047187
FTH1	-0.047143
VDAC2	0.047131
RNASEK	-0.046947
RPL6	0.046882
RPL4	0.046697
CTSS	-0.045860
ATP5G3	0.045474
MAPT	-0.044910
RETSAT	-0.044697
ATP5G1	0.044692
NPTX1	-0.044542
UQCRQ	0.044538
LAMP2	-0.044151
UQCRB	0.044088
MOG	-0.043603
HMGCS1	-0.043425
RPL27	0.043244
HOXA5	-0.043066
H2AFZ	0.042624
UQCRHL	0.042377
SEMA6D	-0.042326
RPS3	0.042148
PCBP2	0.041913
CALB1	-0.041856
PRDX2	0.041729
EEF1B2	0.040991
GSN	-0.040976
ATP5L	0.040849
PRNP	-0.040641
CALB2	0.040450
BTG1	-0.040338
ATP5F1	0.040294
PGK1	0.040261
PSAT1	-0.040246
AGT	-0.040058
EML2	0.039841
UCHL1	0.039837
GABRG2	0.039687
EIF4A2	0.039570
TSPAN3	0.039546
GSTP1	-0.039261
SPP1	0.039227
ITIH3	0.038621
PLP1	-0.038556
NDUFA2	0.038527
SEPW1	0.038307
RNF14	0.038218
CFL1	-0.038029
LAMP5	0.037853
RPL7	0.037788
ENO2	0.037631
ACTG1	-0.037236
SERPINE2	0.036902
RPLP0	0.036837
TM2D3	0.036776
NDUFA6	0.036758
LY6H	0.036594
RHOB	-0.036411
EEF1G	0.035742
PPIA	0.035453
KAT2B	-0.035435
NDUFS2	0.035345
PFDN6	0.035244
MGST1	-0.035059
FAU	-0.034974
HSPE1	0.034874
NDUFS7	0.034624
PSMB4	0.034514
CMAS	0.034244
QDPR	-0.034233
RTN4	0.033927
MGST3	0.033872
RESP18	0.033688
MAP1A	0.033612
LITAF	-0.033554
AP1S2	0.033421
NDUFA4	0.033405
PSMB1	0.033288
EMC4	0.033267
BRSK1	0.033242
SLC25A3	0.033077
MRFAP1	0.033032
SWI5	0.032917
SEPT4	-0.032696
TMEM59	0.032610
BSG	0.032590
SLC25A4	0.032585
EIF3M	0.032582
PRDX5	0.032475
NDUFA8	0.032340
CA2	0.032321
NEFL	0.032024
TRH	-0.031482
AQP4	-0.031435
VAMP1	0.031417
NDUFA1	0.031205
PGAM1	0.031130
RPL21	0.031094
NPC2	-0.030992
TMX2	0.030941
PEBP1	0.030912
UBA3	0.030901
ATP6V0C	0.030890
PLEKHH1	-0.030847
PIP4K2A	-0.030812
COX2	-0.030689
GLRX3	0.030628
RPS16	0.030626
PPP3CA	-0.030428
NDUFB2	0.030323
TMEM130	0.030245
TXNIP	-0.030235
SPTAN1	0.029885
ATP1A2	-0.029869
HSPA4	0.029770
TALDO1	-0.029761
DYNLT3	0.029734
ATP6V0D1	0.029611
GRINA	0.029384
VDAC1	0.029375
TRIM2	-0.029350
YWHAG	0.029295
HSPD1	0.029278
TMEM176B	-0.029236
SERINC3	0.029233
DBI	0.029226
TMEM30A	-0.029206
GJA1	-0.029200
ACTA1	0.029191
ND1	0.029092
ACO2	0.028966
EEF2	0.028874
AKR1A1	0.028847
MDH1	0.028819
RPL35	0.028694
KLHDC2	0.028560
SEP15	0.028513
RBM5	-0.028398
CNBP	-0.028245
NDUFS1	0.028075
USP14	0.028045
TMX4	0.028026
SCN4B	0.027976
NDUFB3	0.027969
NDUFV2	0.027751
PSMD12	0.027638
IGFBP2	0.027636
RPS26	0.027570
ATP6V0B	0.027513
C1QL1	-0.027360
RPS5	0.027264
CD9	-0.027136
RAN	0.027100
ZWINT	0.027050
RAB3A	0.027022
PSMB6	0.027007
CPD	-0.026996
PRAF2	0.026969
RPS15	0.026899
TPPP	-0.026866
GPX4	0.026802
MRPL17	0.026766
RELN	-0.026624
CYP26B1	0.026610
TMEM41B	0.026586
ELOVL1	-0.026540
ITM2B	-0.026496
TUBA4A	0.026486
RPS10	0.026440
RPL27A	0.026338
RPN1	0.026214
NDUFS3	0.026150
WSCD1	-0.025998
METRN	0.025963
APLP1	0.025952
RPL19	0.025741
PPP1R14A	-0.025621
TMCC3	-0.025512
HSP90AA1	0.025432
AGPAT4	-0.025346
CLASP2	-0.025306
COX7A2L	0.025199
YTHDF2	-0.025167
TSC22D3	0.025100
NDUFA12	0.025090
MARCKSL1	-0.024973
PSAP	-0.024973
CYCS	0.024821
DDX17	-0.024773
EVI2A	-0.024764
GSTO1	0.024687
AARS	-0.024486
C1QBP	0.024484
THY1	0.024459
RNF13	-0.024412
SUMO1	0.024393
TPI1	0.024352
TMA7	0.024279
RPN2	0.024272
NDFIP1	0.024171
PFKP	0.024165
TMBIM6	-0.024155
SRP14	0.024076
PSMB7	0.024022
IDH3G	0.023984
TXN	0.023970
HSPA5	0.023873
SYNGR3	0.023662
PYGB	0.023636
VAPA	0.023612
COPS5	0.023506
RPS23	-0.023493
NDUFB11	0.023472
CNN3	-0.023470
GLUL	-0.023316
MAP1LC3A	0.023218
ATP6V1G2	0.023071
RPL7A	0.023019
NRSN1	0.022959
MBP	-0.022932
RPL18A	0.022927
MEA1	0.022924
C12orf57	0.022863
ATP5A1	0.022697
TSPAN7	0.022673
BAP1	0.022665
CTSD	0.022616
ZDHHC20	-0.022606
MRPL41	0.022595
CYP51A1	-0.022526
SGK1	-0.022383
SLC4A4	-0.022375
MYCBP2	-0.022356
SDHB	0.022353
ND2	0.022350
ERMN	-0.022291
GABARAPL2	0.022234
SLC25A5	0.022150
RPL36AL	0.022141
SV2A	0.021997
CLEC2L	0.021961
SPARC	0.021844
RPS12	0.021781
RTN3	-0.021752
GPD1	-0.021696
GDI2	-0.021621
NME2	0.021490
ENPP4	-0.021354
TUBB4B	0.021226
CHGA	0.021201
PLLP	-0.021058
SLC38A2	0.021054
HEBP2	0.021032
UQCRFS1	0.020936
OCIAD1	0.020890
GABARAPL1	0.020881
SC5D	-0.020820
PRKCSH	-0.020818
SYP	0.020775
CDH22	-0.020771
TAGLN3	-0.020758
APP	-0.020644
CST3	-0.020614
NAT8L	0.020612
CPE	-0.020552
PCSK1N	0.020538
PAM16	0.020531
PPA1	0.020301
DYNLL2	0.020245
ARHGEF4	0.020170
RAB14	-0.020144
PAFAH1B1	0.020137
COX5A	0.020085
FLOT1	0.020057
ERH	0.020008
CA14	-0.019923
DLST	-0.019890
NDRG1	-0.019822
COA3	0.019811
SLC32A1	0.019791
ZNF385A	0.019790
NDUFB6	0.019778
SERINC5	-0.019700
RASGRF1	0.019692
MPC1	0.019690
TSPYL4	-0.019675
RPL11	0.019671
HINT1	0.019661
UBC	-0.019645
CAPZA1	0.019622
MBOAT7	0.019607
FAM213B	0.019570
SCN3A	-0.019525
TOMM7	0.019495
STIP1	0.019452
PITHD1	0.019442
RPS2	-0.019422
NDUFV1	0.019350
LANCL1	0.019326
CD83	0.019302
MLF2	0.019285
GRSF1	0.019273
HOXB6	-0.019228
RTN1	0.019158
REEP5	0.019124
PSMC1	0.019095
CFL2	0.019079
CDS1	0.019025
GAD1	0.018985
GPS1	0.018956
GPX1	0.018938
C3	-0.018896
ALDOC	-0.018861
GUK1	0.018836
FKBP1A	-0.018821
PVALB	0.018751
SOD1	-0.018735
GHITM	-0.018724
HABP4	0.018619
ATP5G2	-0.018614
RPL10A	0.018564
PSMC5	0.018555
SET	-0.018553
MAL	-0.018544
RAB6B	0.018439
NDUFC2	0.018405
RAP1GAP	0.018386
FN1	-0.018382
VCP	-0.018379
SERINC1	0.018362
HNRNPH1	-0.018339
RNF208	0.018329
LIMK1	0.018328
RHOG	-0.018328
GAPDH	-0.018309
CTNNA1	-0.018258
CMTM5	-0.018230
KLC2	0.018228
CLDN5	0.018225
TOMM20	0.018213
RPL12	0.018210
GRM3	-0.018210
PDIA3	0.018172
RHOA	0.018163
RPSA	0.018138
CLTC	0.018134
DYNC1H1	0.018113
BOLA3	0.018111
PAPSS1	-0.018097
SIRT2	-0.018056
EPDR1	0.018022
NCDN	0.018016
STUB1	0.017981
PRMT1	0.017947
CLK1	-0.017917
LAMTOR2	0.017907
TBCA	0.017828
HIBADH	-0.017826
DMTN	0.017808
MAP2	0.017766
SGCB	-0.017757
PIK3R1	-0.017741
CHPF	0.017739
SEPT8	-0.017688
SDCBP	0.017674
HOXB5	-0.017655
COX8A	0.017646
LSAMP	-0.017622
DZIP1	0.017524
STMN2	0.017467
ASPA	-0.017311
SELT	-0.017216
CLCN3	-0.017213
SYTL2	-0.017173
FCER1G	-0.017155
LCAT	-0.017153
SYNPR	-0.017122
SARNP	0.017080
MTMR6	0.017058
FKBP3	0.017025
ATP6V0A1	0.017001
DSTN	-0.016999
NEK7	0.016944
RABAC1	0.016898
CLSTN1	0.016886
ATP1A1	-0.016885
MRPL54	0.016876
MTX2	0.016874
MYRF	-0.016871
RAC1	-0.016806
RIT2	0.016783
RPS9	0.016767
MAPK3	-0.016767
CALR	0.016755
TMEM179	0.016729
FAIM2	0.016633
LGALS1	0.016622
SMARCD3	0.016604
FLCN	-0.016602
SDHD	0.016583
DAZAP2	-0.016566
SHFM1	0.016552
TWSG1	0.016530
CHMP2A	0.016523
TMBIM4	-0.016488
PPIB	-0.016462
ALDOA	-0.016378
TIMM17A	0.016364
CTXN2	0.016334
NDUFC1	0.016251
SOD2	0.016224
HSPA4L	0.016199