!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Mus musculus
!drug_name	coenzyme Q10
!smiles	CC1=C(C(=O)C(=C(C1=O)OC)OC)CC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C
!pubchem_cid	5281915
!cell_type	liver
!organism	mouse
!end_metadata
SERPINA6	-0.336094
FABP1	0.262927
FETUB	-0.247392
BHMT	0.195957
TTR	0.140256
APOE	0.128321
CYP2E1	0.120430
FMO3	0.103929
HMGCS1	-0.100776
MSMO1	-0.100651
RPS29	0.100546
PIGR	-0.100529
ACAT2	-0.099858
SAA1	0.092277
CTH	0.091779
USMG5	-0.089585
GLUD1	-0.088798
HP	0.087776
FGL1	-0.084373
CDO1	-0.083025
CFI	-0.082801
ETHE1	-0.081294
IDI1	-0.080986
HAL	0.080477
SEPP1	0.080131
CAT	0.079749
AHSG	-0.078967
HPD	0.075519
UQCRB	-0.074931
TAT	-0.071731
APOA5	0.071699
RPL27A	0.071160
FTL	0.070797
SCD	-0.066096
INMT	-0.065551
RPL38	0.064205
GC	0.064072
HRSP12	0.063539
EEF1A1	0.063490
F13B	-0.063084
HSPA5	-0.062822
MANF	-0.062743
EPHX1	-0.062654
CHCHD10	0.062643
AKR1A1	-0.062269
SQLE	-0.061578
LAMP2	-0.061338
PGK1	-0.060682
APCS	-0.060351
SDS	0.059848
PPIA	-0.059684
ALDH9A1	0.059195
UGDH	-0.058373
CFH	-0.058025
HSP90AB1	-0.057800
RBP4	0.057508
GPX4	-0.057411
TGM2	-0.057338
PHYH	-0.057107
FDPS	-0.055933
RPL37A	0.055678
CYP7A1	-0.055266
SERPINF1	-0.054708
TM7SF2	-0.053421
FXYD1	-0.052797
AGT	-0.052701
HPX	-0.052654
FBP1	-0.052421
NDUFA4	-0.052345
HSP90B1	-0.052144
PSMB7	-0.051926
GPLD1	-0.051774
SERPINA10	-0.051746
CES1	-0.051720
MLXIPL	0.051286
PNP	-0.051092
CPS1	0.050340
CYC1	-0.050338
C3	-0.050060
ATP6V0C	-0.049702
LAPTM4A	-0.049197
SLC27A5	-0.048771
HERPUD1	-0.048199
C14orf1	-0.047690
RPS11	0.046824
TTC36	0.046727
GJB2	-0.045860
SEPHS2	0.045531
PAH	0.045431
RPS28	0.044881
FAH	0.044555
ARL5A	-0.044297
RGN	-0.043188
BSG	-0.043087
DMGDH	-0.042973
RPL4	-0.042817
SERPINB1	0.041745
PNPO	-0.041674
REEP6	0.041332
TECR	-0.041226
CHCHD2	0.041101
CYP2F1	-0.040690
IGFBP2	0.040569
NDUFA1	-0.040560
UGT2B17	-0.040534
HAO2	-0.040365
MORF4L2	-0.039877
DHCR7	-0.039825
ETFB	0.039478
EHHADH	-0.039459
ACSS2	-0.039127
FDX1	-0.039109
LGALS9B	-0.039095
MAOB	-0.038795
CSAD	-0.038779
CYP8B1	-0.038481
DNAJB9	-0.038443
ARRDC3	0.038029
APOA1	0.037867
HINT1	-0.037738
CYCS	-0.037326
COX5A	-0.037033
TMBIM6	0.036881
ITIH4	-0.036582
HIBADH	-0.035948
ALAD	0.035890
UGT2B7	0.035645
CYP2C8	-0.035313
HSP90AA1	-0.035272
RPL26	0.035028
APOC4	-0.035003
APOH	0.034775
SDC4	-0.034656
COX6B1	-0.034579
RPS15	0.034493
SOD1	0.034066
EPHX2	0.033837
TMA7	-0.033652
TP53INP1	-0.033302
MCFD2	-0.033105
HAGH	0.033104
SLC25A39	-0.032435
PSMA4	-0.032422
UQCRC2	0.032411
ITIH2	-0.032182
RPS2	0.032121
FGB	-0.031835
GCKR	0.031794
SLC22A1	-0.031751
RPL21	0.031452
ITIH1	-0.031172
CYP1A2	0.031148
RPL10	0.031134
SLC38A3	0.030855
NRN1	-0.030786
CMBL	0.030779
RPS14	-0.030680
ASS1	0.030607
PARK7	0.030600
F2	-0.030575
PTGES3	-0.030497
ALB	-0.029979
ME1	-0.029862
RDH11	-0.029784
ACLY	-0.029485
HAX1	-0.029380
INSIG1	-0.029357
F12	-0.029277
SLC27A2	0.029207
RPS12	0.029192
NDRG2	0.029086
HAO1	-0.028985
TMEM176B	-0.028922
SLC9A3R1	-0.028833
B2M	0.028480
AMFR	-0.028447
FABP2	0.028417
CCBL2	0.028208
NDUFA2	0.028203
DHCR24	-0.027981
LACTB2	-0.027932
TPT1	0.027900
ACSL5	-0.027834
C1QBP	-0.027807
RPL28	0.027789
PDIA4	-0.027755
NIPSNAP1	-0.027717
CYP51A1	-0.027629
MGST1	0.027602
CCT6A	-0.027400
CP	0.027288
IGFBP1	-0.027256
APOA2	0.027165
PDIA5	-0.027140
CYP3A7	-0.027038
NAT8B	0.027024
FDFT1	-0.027007
RPL7A	0.026813
RPL35	0.026750
APOB	-0.026692
DDT	0.026657
CALR	-0.026649
ERRFI1	-0.026585
SERPINA1	0.026473
PON1	0.026377
CRP	-0.026364
RPS26	0.026258
P4HB	-0.026185
RNF128	-0.025946
CNIH1	-0.025940
SERPINF2	-0.025870
AQP8	-0.025834
CREG1	-0.025696
PEMT	-0.025533
PRDX1	-0.025371
ATP5G3	-0.025333
PM20D1	-0.025310
AHCY	0.025206
ACOX1	0.025201
CEBPA	0.025035
NDUFS6	-0.025028
AZGP1	0.024942
GLS2	0.024922
PXMP2	0.024887
NDFIP1	-0.024880
FTCD	0.024529
VDAC1	-0.024511
TSC22D3	-0.024485
ID2	0.024420
RPL8	-0.024306
SEC14L2	0.024241
RPL23	0.024160
HNRNPA2B1	0.024050
LDHA	-0.024043
AGMO	-0.023947
GABARAP	-0.023894
RPL7	0.023649
COX6A1	0.023546
AGMAT	0.023382
PAQR9	-0.023233
NDUFS8	-0.023023
ATP5D	-0.022974
SLC40A1	-0.022971
AFM	0.022786
GNMT	-0.022725
RPLP0	-0.022636
ALDH3A2	0.022601
THRSP	-0.022571
SDC1	-0.022548
TIMM23	-0.022506
CPB2	-0.022380
UGT3A1	-0.022333
PDIA3	-0.022173
VKORC1	-0.022110
NME2	-0.022090
HSD17B6	0.022082
HACL1	0.022039
SREBF1	0.021982
NR0B2	0.021884
ASL	0.021806
CRELD2	-0.021761
SERPINA11	-0.021741
DAP	-0.021725
ST3GAL4	-0.021720
ACAD11	0.021679
PSMB4	-0.021645
PCBP1	-0.021557
SLC37A4	-0.021443
FN1	-0.021370
DERL2	-0.021332
CIDEB	-0.021328
RPLP2	0.021218
ECI2	0.021194
MPC1	-0.021094
SC5D	-0.021066
AASS	-0.020981
PMVK	-0.020961
TKT	0.020955
OAT	0.020928
RPS27A	-0.020903
PPIB	0.020903
C6	-0.020903
CD81	-0.020867
NDUFA13	-0.020799
PLG	0.020712
KLKB1	0.020692
MSRA	-0.020674
MLF2	-0.020491
DDX17	0.020462
EI24	-0.020317
HSD3B7	0.020290
EIF4A2	0.020076
NDUFB8	-0.020075
GPI	-0.020010
RPS5	-0.019950
PHB2	0.019909
FAU	0.019892
RPL3	-0.019887
ALDH6A1	-0.019823
SCP2	-0.019823
RPL10A	0.019788
TMED2	-0.019631
RPS23	0.019608
GCGR	0.019591
DDX3X	-0.019572
CEPT1	-0.019523
DNAJA1	-0.019425
HMGCS2	0.019347
ACTB	-0.019334
PCK1	-0.019321
RPL13	-0.019280
DNAJC3	-0.019172
NDUFA8	-0.019155
HEBP1	-0.019117
SEC61G	-0.018760
ALDH2	0.018750
ARG1	-0.018737
HSD17B12	-0.018662
NDUFA5	-0.018598
ATP5A1	-0.018593
TFR2	-0.018587
GJB1	-0.018528
RPL6	0.018509
SORD	-0.018371
TFPI2	-0.018357
RPS24	0.018270
SAR1B	-0.018222
CROT	0.018200
RPL9	-0.018186
RPL14	0.018172
SDC2	-0.018140
SPCS2	-0.018060
TMEM30A	-0.017717
SLC38A4	-0.017648
ITIH3	-0.017620
ECI1	0.017606
LPIN1	-0.017600
AQP9	-0.017580
RPL19	-0.017580
RPL18A	0.017568
ACSM1	-0.017550
RPN1	-0.017520
NDUFS2	0.017457
CTSD	-0.017368
CCNL1	0.017365
GLRX5	-0.017354
VTN	0.017320
RPL5	-0.017174
BNIP3	-0.017141
UGT2A3	0.017118
UPB1	-0.017070
CA3	0.017053
ARF1	-0.017036
HADH	0.016974
DVL1	0.016940
SLC2A2	-0.016925
DNASE2	-0.016917
TPI1	-0.016886
RPS21	0.016867
SGK1	-0.016841
PPARA	0.016830
ACAA2	0.016783
GPAM	-0.016777
TMEM14C	-0.016724
MAT1A	-0.016705
PSMB5	-0.016674
ADK	0.016596
RPS25	0.016508
ACADM	0.016476
MAGT1	-0.016392
PPP1R3B	-0.016387
PRDX3	-0.016342
GLDC	0.016336
SLC16A7	-0.016331
OSBPL1A	-0.016231
MBL2	0.016208
TXNDC5	-0.016198
CYP4F8	0.016178
IFITM2	-0.016171
PPP2R5A	-0.016141
DCXR	0.016085
RNASE4	0.015975
CSDE1	-0.015960
SDHD	-0.015865
MID1IP1	0.015779
AMY2A	-0.015766
RAB1A	-0.015749
EIF5A	-0.015678
POSTN	-0.015645
ARHGDIA	-0.015632
NDUFV2	-0.015519
COX8A	-0.015506
CCNL2	0.015489
ABCB11	0.015446
BHMT2	0.015418
SLC47A1	-0.015416
SQRDL	-0.015366
AGXT	0.015360
EBP	-0.015350
FTH1	-0.015210
KRT18	0.015207
PFN1	-0.015191
RDX	0.015145
MAN1A1	-0.015138
DAZAP2	-0.015115
HSD17B7	-0.015109
NSDHL	-0.015087
G0S2	0.015083
ATF5	-0.015013
SLC25A16	-0.014991
SCO2	0.014988
TMEM150A	0.014920
ECHDC1	-0.014904
SERP1	-0.014874
CA5A	0.014817
MDH2	-0.014816
DUSP1	0.014804
NLRP6	0.014676
TMPRSS6	-0.014657
EDEM1	-0.014636
C8G	0.014622
SGK2	0.014608
C8A	-0.014574
AP3S1	-0.014512
RAB18	-0.014467
NARS	-0.014447
NDUFB3	0.014397
SELENBP1	0.014394
ATP8B1	-0.014387
NDUFB9	-0.014382
DNAJB11	-0.014373
TUBA4A	0.014366
GCLM	-0.014295
AKR1C4	-0.014252
PCNP	-0.014217
CTSC	-0.014202
GPX1	0.014200
SCPEP1	-0.014200
PCYT2	0.014126
IDH1	-0.014067
NNMT	-0.014061
KDELR2	-0.014029
PANK3	-0.013997
C11orf54	-0.013978
RPL24	0.013978
PGAM1	-0.013912
C9	-0.013884
GHITM	-0.013884
CYB5B	-0.013845
NLRP12	-0.013845
SLC17A2	-0.013843
SLC16A12	-0.013838
NDUFB7	-0.013778
PGLYRP2	-0.013777
HSD17B2	-0.013679
TMEM256	-0.013607
C19orf80	0.013580
NDUFA12	0.013555
VAMP7	-0.013547
DSC2	-0.013492
LUC7L2	0.013476
GSTM5	0.013454
HEXB	0.013414
SUCNR1	0.013389
PRDX4	-0.013379
ID3	0.013372
HSPE1	-0.013368
ECHDC2	0.013357
RAB5A	-0.013328
ILDR2	-0.013301
RANBP1	-0.013294
MGAT2	-0.013291
S100A10	0.013285
GCLC	0.013273
ALDH4A1	-0.013256
ATP5H	0.013250
SERF2	0.013243
ASGR2	0.013219
SH3BGRL	-0.013211
NUDT4	-0.013203
HMGCR	-0.013201
CCS	0.013177
LECT2	0.013148
CBR1	0.013086
SNRPD2	0.013037
DEK	-0.013033
PSMC5	-0.013032
PEX7	-0.012991
NDUFB10	0.012986
RPS13	-0.012974
CFHR1	-0.012974
CLPTM1L	-0.012950
SAT1	0.012930
HIGD2A	-0.012925
PSME1	-0.012910
UQCRQ	-0.012885
DYNLT3	-0.012866
TF	0.012853
NDUFV1	-0.012841
AK2	0.012783