!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	Curcumin
!smiles	COC1=C(C=CC(=C1)C=CC(=O)CC(=O)C=CC2=CC(=C(C=C2)O)OC)O
!pubchem_cid	969516
!cell_type	U937 cell line (monocyte)
!organism	human
!end_metadata
HSPA1A	-0.228763
IFI30	0.192996
BCL2A1	-0.123016
MMP9	0.116158
FTL	0.115117
GAPDH	0.115088
HERPUD1	-0.112492
ATF4	-0.109028
RPS10	0.103232
ACTB	0.103050
COX1	0.100511
FTH1P5	0.099707
RPL9	0.098553
FTH1	0.094938
RPS18	0.093665
EEF1B2	-0.093378
ALOX5AP	0.091564
PLIN2	-0.084795
HMOX1	-0.084228
COX2	0.082703
MMP7	-0.082186
CXCR4	-0.078973
DNAJB9	-0.078970
LAPTM5	0.078778
PLP2	0.077380
RPLP0	0.077157
HSPE1	-0.075809
TPT1	0.074166
RPL23A	0.073858
RGS2	-0.073215
RPS17	0.072385
CCL2	0.072236
MMP1	0.071177
CTSH	-0.070732
RPL39	0.070697
HSP90AA1	-0.070222
DNAJB1	-0.069602
SRXN1	-0.067938
ND2	0.067436
LASP1	-0.066374
HSP90AB1	-0.065582
S100A4	0.065469
CAPG	0.064910
CFL1	0.064832
TMEM158	0.064637
EGR2	-0.064212
RPS8	-0.063953
GLO1	0.063910
HSPA8	-0.063755
NPC2	0.061971
RPL32	0.061775
S100A9	0.061432
TPSB2	0.060905
ARL6IP5	0.060490
ATF3	-0.060001
ATP6V0B	0.059712
CKS2	-0.059709
LYZ	0.059676
FABP4	0.058976
SHFM1	0.058445
RPS4X	0.058348
HSPB1	-0.057833
LDHA	0.057772
CITED2	-0.057633
B2M	0.057427
PSAP	0.057000
SSR2	-0.056934
SPP1	0.055620
DNAJA1	-0.054682
LCP1	0.054602
RPS5	0.054439
TM4SF1	-0.053976
ALDOA	0.053658
SLC25A5	0.053435
PRDX1	0.053286
HSPH1	-0.053155
ENC1	0.053076
GPI	0.052740
FABP5	-0.052307
TPSAB1	0.051928
RPL41	0.051633
TMEM123	-0.050992
CLEC2B	0.050827
RPS3	0.050219
JUN	-0.049733
CCL7	-0.049691
IER3	-0.049616
HSPA5	-0.049604
RPL10A	0.049370
ABHD3	-0.049127
MT2A	-0.048051
RPL37A	0.047928
ARPC1B	-0.047898
SRP9	-0.047825
IRF2BPL	0.047816
RPS2	0.047287
PPIA	0.047254
CD93	0.047030
EEF1A1	0.046408
SNHG1	0.046405
RPL35	0.046351
RPL30	0.045949
PTGES3	-0.045871
DUSP5	-0.045614
HMGN2	-0.045424
SLC7A7	0.044920
LGALS1	0.044724
RPS15	0.044634
RCBTB2	0.044620
CD83	-0.043836
DEDD2	-0.043558
RPLP1	0.043424
CXCL8	0.043362
EEF1G	0.043335
TYROBP	0.043267
PKM	0.043180
TMEM258	-0.043146
CST7	0.042804
TDP2	-0.042675
ANXA2	0.042550
TMBIM6	0.042429
SUCNR1	0.042288
ATP6AP1	0.042048
EIF4H	0.041722
NSMAF	-0.041541
RPL36	-0.041517
LINC00657	-0.041395
CXCL10	0.039697
BAG3	-0.039613
S100A8	0.039512
SEC61B	-0.039438
ZFAND2A	-0.039381
PPT1	0.039319
LGALS3	0.039093
DEK	-0.039092
FLNA	-0.039017
RPL24	0.038915
MT1X	-0.038777
VIM	0.038439
SERPINB2	0.038369
SLC38A2	-0.038248
MAFF	-0.038078
SNHG5	0.037771
LITAF	-0.037753
LRIF1	-0.037705
RPL12	0.037701
AP2M1	0.037639
ACSL1	-0.037613
ITGB2	0.036598
CAPN2	0.036517
HLA-A	0.036462
IFITM2	-0.036415
FNIP2	-0.036302
PIM1	-0.036260
RPS3A	0.036146
LSM7	-0.036139
RPS7	0.035791
SAT1	0.035700
CES1	0.035494
AQP9	-0.035424
CHIC2	-0.035314
PMAIP1	-0.034832
MMADHC	0.034372
ACTG1	0.034363
CORO1A	0.034221
OAZ1	0.034126
MT1E	-0.034104
DUSP1	-0.034057
NPM1	0.033939
RPS25	-0.033792
PTTG1IP	0.033652
PPP1R15A	-0.033647
HNRNPK	-0.033619
MGAT1	-0.033460
CHIT1	0.033359
CHSY1	-0.033351
HLA-B	0.033344
MTCH1	0.033165
TUBA1C	0.033039
ARPC2	0.032919
NDRG1	0.032699
SLA	0.032625
RGS16	0.032595
MAFB	0.032579
CNBP	-0.032489
CCL1	0.032278
SNRPB2	-0.032269
TMA7	0.032265
DBI	-0.032245
FGR	-0.032140
MYL12A	-0.032071
STARD3NL	-0.031891
TRIB3	-0.031848
PLEK	-0.031773
HK2	-0.031465
MANF	-0.031339
GPNMB	0.031012
VIMP	-0.030923
C19orf10	-0.030870
PRDX4	-0.030434
ARPC5	0.030299
UBB	-0.030173
MALAT1	0.029812
WDR82	-0.029780
THBD	-0.029775
MIR21	0.029602
ANXA2P2	0.029583
RPS20	0.029553
RPL17	0.029475
ISG15	-0.029354
AHSA1	-0.029138
SLC7A11	-0.029097
ATP6V1G1	-0.029090
SLC17A5	-0.029083
SEP15	-0.029065
IER2	0.028990
IFIT2	0.028840
VWA5A	0.028834
RPL26	-0.028716
NQO1	0.028693
MFSD1	0.028650
GPX1	0.028618
S100A10	0.028536
ENO1	0.028353
HPCAL1	0.028185
GBE1	0.028152
RAB1A	-0.028059
IDH1	-0.027883
H1F0	-0.027807
UQCRH	0.027634
ATP6	0.027618
P4HB	-0.027589
HIST1H2BK	-0.027537
TIMP1	0.027536
MAPK6	-0.027533
SERF2	0.027506
MMP12	0.027434
SQRDL	0.027348
IRS2	0.027160
MTHFD2	-0.026915
SCD	0.026883
TXNDC12	0.026805
NDUFB9	0.026737
RAC2	0.026679
IER5	-0.026480
APOC2	0.026438
ATP6V1A	0.026403
HLA-C	0.026379
MNDA	-0.026370
CD164	-0.026277
UBE2L6	-0.026258
COA6	-0.026201
PSME2	0.026198
SELK	-0.026158
POLR2J	0.026030
CYFIP1	0.026024
OSBPL8	-0.025982
RPS24	0.025868
RPS26	-0.025865
OSTC	-0.025791
TCEB1	-0.025760
FXYD5	0.025736
IFIT1	0.025721
TBCA	-0.025438
HUWE1	0.025395
SRP14	0.025368
DSTN	0.025226
TGFBR1	-0.025173
LAPTM4A	0.024971
LAMTOR5	-0.024891
MT1H	-0.024883
TDO2	-0.024811
SGK1	0.024767
GPR34	0.024762
SLBP	-0.024720
CAPNS1	-0.024539
SRP19	-0.024458
DTX3L	-0.024453
DPM1	-0.024386
DENND5A	-0.024326
PPP1R15B	-0.024321
PSMC6	-0.024298
RPL11	-0.024205
YWHAZ	0.024172
SERTAD2	-0.024136
RPN2	0.024120
NDUFAB1	-0.024094
CCR1	-0.024042
CHMP5	-0.024008
HCST	0.023999
ATP5B	-0.023893
IQGAP1	0.023884
GNB2L1	0.023765
TTYH3	-0.023661
PNN	0.023639
CLIC1	0.023513
SMAP1	-0.023486
ATP6V1E1	0.023449
CSGALNACT2	-0.023362
EIF2A	-0.023349
DUSP6	-0.023312
C3AR1	0.023291
HSPA13	-0.023283
CCT3	-0.023282
CYTIP	-0.023271
CTSS	-0.023190
FAU	-0.023169
ARPC3	-0.023135
CKS1B	-0.023037
EEF2	-0.023009
ANXA1	0.022979
NDEL1	-0.022964
PSMB3	0.022933
PPIB	-0.022873
CD52	0.022840
SEC11A	0.022822
TCEB2	0.022821
RPS27	0.022784
ARF4	-0.022753
PABPC3	0.022751
NME1	-0.022733
TNFSF15	-0.022698
HSPA6	-0.022581
FUCA1	0.022524
NPC1	-0.022509
PFKFB3	0.022396
RAP2A	0.022369
RPS12	0.022364
EIF3E	-0.022325
YBX1	0.022265
OLIG1	-0.022167
PSMB8	-0.022147
GORASP2	-0.022105
CEBPB	-0.022104
ATP1B3	0.022101
YRDC	-0.022020
UBE2Q2	-0.021993
DUT	-0.021938
RPS13	-0.021875
PCNA	-0.021681
FKBP1A	-0.021609
PPARD	0.021513
SSR4	0.021504
B4GALT5	-0.021433
NACA	0.021421
DLD	-0.021396
CSK	0.021355
NDUFA1	0.021259
CSNK2B	0.021217
CBX3	-0.021205
LBR	-0.021134
HIST1H2AC	-0.021099
YWHAG	-0.021091
PPIF	0.021077
GNAS	0.021063
MYL12B	0.020968
MID1IP1	-0.020913
RPS16	0.020894
SLC5A3	0.020885
RAN	-0.020873
CD99	0.020866
CLEC5A	-0.020799
TXNRD1	-0.020765
GSR	-0.020754
COX7A2	-0.020713
RARS	-0.020685
TAP1	0.020682
RNF4	-0.020649
BZW1	0.020634
KLF6	-0.020574
IDH3B	0.020551
MX2	-0.020536
STK24	0.020323
CCL4	0.020208
RNASE2	0.020153
RGS19	0.020136
MMP3	0.020101
MYADM	-0.020047
TUBB3	-0.020021
SLC25A6	-0.020008
TOMM20	-0.020003
ITGA6	-0.019964
SERPINE1	0.019921
UBC	0.019915
EIF3H	0.019893
RPS19	0.019722
IARS	-0.019710
EMR2	0.019658
GPX4	-0.019658
SNRPB	-0.019465
SARAF	-0.019421
EIF1	-0.019400
RNF149	-0.019373
POLR2G	0.019347
IL4I1	0.019313
SQLE	0.019309
GABARAPL2	-0.019246
QARS	0.019238
IFI6	-0.019173
RPS15A	0.019161
PARP4	-0.019158
BTG1	-0.019152
CXCL3	-0.019149
NEU1	0.019099
MARCKSL1	0.018980
TRMT5	-0.018961
HEBP2	0.018939
AIDA	-0.018937
PPP4C	-0.018916
PDK1	0.018879
RRM2	-0.018815
HSPD1	-0.018809
CXCL2	-0.018802
ICAM1	0.018787
MOB4	-0.018766
GCLM	-0.018705
MRPL18	-0.018682
NAMPT	-0.018663
IFITM1	-0.018646
GRN	0.018593
LMNA	0.018591
XPOT	-0.018590
NPTN	-0.018541
PSMA6	-0.018527
CACYBP	-0.018518
DYNC1I2	-0.018464
MAN2B1	0.018461
TUBB4B	-0.018445
IMPA1	0.018403
NDUFB4	0.018392
RPS21	0.018385
RPS28	0.018360
ADO	-0.018295
ZNF267	-0.018293
NDUFAF1	0.018290
GLB1	0.018281
RNH1	-0.018250
RPL18	0.018246
PTPLAD1	0.018231
AP1S2	0.018162
METTL9	-0.018143
NFE4	-0.018076
RPL4	0.018005
NHP2	-0.017988
FCGR2B	0.017952
NDUFA4	0.017909
MT1HL1	-0.017876
SLC20A1	0.017867
SLC1A5	-0.017812
UBL5	-0.017734
BRI3	-0.017733
CD163	0.017732
IL7R	0.017726
MGAT2	-0.017664
ZC3HAV1	-0.017580
NDUFB3	0.017554
SNRPG	-0.017500
ITM2B	0.017468
MS4A4A	-0.017444
CD163L1	0.017347
TOP2B	-0.017280
ENOPH1	-0.017277
DNAJB11	-0.017264
RPL21	0.017240
AP2S1	0.017195
CD63	0.017171
CNEP1R1	-0.017154
PNRC1	-0.017150
TTC19	-0.017046
BTF3	0.017020
CTSB	0.017019
GOLGA4	-0.016961
CTNNB1	0.016918
ITPA	-0.016882
PPP1R18	-0.016877
FCAR	-0.016875
GFPT1	-0.016870
MIS12	-0.016765
TOP1	0.016720
HDAC1	0.016698
KPNA2	-0.016670
TM9SF2	0.016637
PYGL	-0.016571
NCF2	0.016556
EIF1B	-0.016550
NACAP1	-0.016511
GCLC	-0.016484
PSMB9	-0.016470
TMEM59	0.016465
TMED2	-0.016376
OST4	0.016346
RPS11	0.016261
EFR3A	-0.016259
OXSR1	-0.016204
TNFSF13B	0.016124
EID1	0.016118
HSP90B1	-0.016065
IFNGR2	-0.016052
TUBA4A	0.016011
COX6A1	0.016009