!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	rat
!drug_name	2,3,7,8-tetrachlorodibenzo-p-dioxin
!smiles	CC(C)C=CC(=O)ONC(=O)COC1=CC=C(C=C1)[N+](=O)[O-]
!pubchem_cid	10852289
!cell_type	Hypothalamus (postnatal day70 male rats exposed in utero to dioxin at gestational day15)
!organism	rat
!end_metadata
RPS9	0.279043
PTGDS	-0.225339
AVP	-0.199225
RPLP0	-0.197981
PCP4	0.196808
OXT	-0.159356
RPL6	-0.145127
RPS25	0.139028
RPL3	-0.127742
IGF2	-0.124392
SLC17A6	0.123885
YWHAE	0.108121
PPIA	0.105546
TPI1	0.104554
LMO4	-0.102569
CFL1	0.101014
CCK	0.099711
RPSA	-0.099184
SYP	0.096274
ITIH3	-0.095820
YWHAB	0.094751
SLC25A3	-0.087437
RPL9	-0.080887
COX8A	-0.079653
EIF4A2	-0.079251
GNB1	0.075858
PRNP	-0.075696
GABBR2	0.073381
PKIG	-0.073201
RPS4Y1	-0.071578
CALY	0.069858
NDUFB9	-0.068524
NDN	-0.068114
NDRG4	0.067294
NCDN	0.067261
ITM2B	-0.066190
GPRASP1	0.065900
CST3	-0.064928
PARK7	-0.064893
COL1A2	-0.064155
CD81	0.063072
RPL17	-0.063041
RPS27A	0.062919
GAP43	0.062071
RPL27	0.061667
ATP6V0C	0.060929
CLTC	0.060683
PMCH	0.059376
STMN1	0.059217
SEPW1	0.059130
RTN1	0.057310
ENO2	0.056877
TECR	0.056743
SPARCL1	-0.056539
FTL	-0.056232
ATP5C1	-0.056078
NDUFB8	0.055934
RPL10	-0.055455
ATP1B2	0.054255
MOB4	0.053744
OAZ1	-0.051404
CTSS	-0.051366
NDUFV2	-0.051028
RPS26	-0.050758
EEF1A2	0.049615
GAD1	-0.049535
GFAP	-0.047649
RPL35A	0.047646
AGT	0.047215
RPS15	-0.046869
ATP6V1B2	0.046715
TSHB	0.046638
TXNIP	-0.046637
PRKCD	0.046464
SUMO2	0.046242
SNURF	0.046102
RTN4	0.046100
RPS7	0.045984
TXNDC15	-0.045639
GSTM3	-0.045630
RHOA	0.044429
AKR1A1	-0.044374
RPS14	-0.044214
ATP2A2	0.043985
SYT1	0.043710
GPX4	-0.042607
THOC7	-0.042468
RPL8	-0.042423
DYNC1H1	0.042404
TAC1	-0.042293
CYCS	-0.042236
ATP1B1	0.042223
PLEKHB1	-0.041920
CAMK2N1	-0.041808
XBP1	-0.041605
TSPAN3	0.041401
PGK1	0.041274
DDN	-0.041089
AP2S1	-0.040828
MAP2K2	-0.040648
COX7B	0.040497
NDUFA8	0.040446
HSPD1	-0.040373
RPL4	0.040206
PLP1	-0.040100
VDAC2	-0.039787
PFDN5	0.039665
HDAC11	0.039109
NDUFB5	-0.039087
UBQLN2	-0.039012
MFGE8	-0.038672
RGS3	0.038303
NELL2	0.038163
PFKM	0.038042
TUBA4A	0.037882
PMEPA1	-0.037626
KCNC2	0.037086
FEZ1	-0.037025
ATP5J	0.036992
HCFC1R1	-0.036783
SMPD1	-0.036687
CNIH1	-0.036472
ATP5A1	0.036416
CTSB	0.036381
PPP2CB	-0.036160
UCHL1	0.036157
PSMB7	0.036137
RPS20	0.036052
SCG3	-0.035516
PDCD5	-0.035408
STMN3	0.035099
RPL30	0.035024
SPOCK2	0.034920
ID2	-0.034817
FBXO2	-0.034706
RGS7	0.034487
LDHA	0.034483
OLFM1	0.034338
RPS10	-0.034034
SEP15	-0.033875
DAD1	0.033760
TPT1	-0.033557
RPL14	-0.033535
YWHAQ	-0.033349
EEF2	0.033229
RPS17	0.033134
ZER1	0.032831
RBFOX1	-0.032667
CNBP	-0.032653
COX6A1	0.032502
PYGB	0.032216
B2M	0.032144
RNASE4	-0.032099
ABHD4	-0.032040
PSMB4	0.031955
PSMD3	-0.031490
TMEM208	-0.031338
AES	0.031019
LAMP5	-0.030991
ITM2C	0.030647
AP2M1	0.030645
CLASP2	0.030516
GLUD1	0.030475
VDAC3	0.030397
FAM32A	-0.030345
ALDOA	0.029715
OSTC	0.029713
HMGN1	0.029676
MMADHC	0.029669
NACA	0.029619
NEDD8	0.029357
SRP19	0.029250
INA	0.029154
ADORA2A	-0.029051
MORF4L2	0.028953
RRAGA	-0.028936
RPL13	-0.028904
MAGED1	-0.028612
TALDO1	-0.028549
COX5A	-0.028476
ATP5B	0.028454
HABP4	0.028364
OLA1	-0.028296
RPL10A	0.028277
INPP5A	0.028209
CSTB	-0.028170
ANAPC11	-0.027932
HCRT	-0.027853
TOMM20	-0.027773
H2AFX	-0.027732
CTBP1	0.027705
CARTPT	-0.027663
PFDN6	0.027467
HOPX	-0.027405
ENPP5	0.027295
DDAH1	0.027263
CD164	-0.027232
HMGCS1	0.027093
ATP6V1G2	-0.027093
RASD1	0.026894
RGS4	0.026731
CCT6A	-0.026604
CCNI	-0.026590
NELL1	0.026343
BEX1	0.026189
MRPS33	-0.026189
USP14	0.026136
PSMA6	0.025962
BOK	0.025900
RGS9	-0.025886
TUBB3	0.025719
HPCA	-0.025697
RPL18	-0.025663
PSMB1	-0.025663
KCNH3	-0.025228
NKX6-2	-0.025128
RPS3	-0.025039
HNRNPF	-0.024928
MAGEE1	-0.024902
MALSU1	-0.024759
ACAT2	0.024716
UQCRHL	-0.024669
ZNF428	-0.024584
RPL22	-0.024580
ATP6V1G1	-0.024549
MRPL18	0.024535
H2AFY	0.024466
RAB26	-0.024449
THRA	-0.024423
ATXN10	0.024280
RETSAT	-0.024171
NFKBIA	0.024137
MGST1	-0.023989
VIM	-0.023899
TRH	-0.023847
MAP1LC3B	0.023840
CHST1	0.023766
EMC6	-0.023736
TUBA1B	0.023688
PRDX2	0.023674
IGFBP2	-0.023667
PRKCZ	-0.023623
MDH1	0.023606
RCN2	-0.023571
EPHX2	-0.023568
CSPG5	0.023519
SERINC3	0.023408
STMN2	-0.023392
NDRG2	0.023316
HSP90B1	0.023242
CDC37	0.023184
CELF4	-0.023110
MBP	-0.023028
SLC20A1	0.022996
RXRG	-0.022946
GLTP	-0.022789
NTNG1	0.022752
TRAPPC1	0.022719
PDHB	-0.022712
GRIA2	-0.022616
PNP	-0.022604
SPARC	0.022519
CMPK1	-0.022466
STXBP1	0.022369
LCAT	-0.022353
LAMTOR2	-0.022307
RHOB	0.022297
BABAM1	-0.022220
BLCAP	0.022174
SLC1A1	0.022116
ARPC4	0.022110
PPT1	0.022074
QDPR	0.022050
GSTO1	0.022049
NUPR1	-0.022038
EFNB3	-0.022038
SCAND1	-0.022002
NME1	-0.021991
SDHC	0.021938
TTYH1	0.021884
TMEM50A	-0.021867
ATP6V0A1	0.021649
DRG1	0.021581
SELK	0.021550
MFN2	0.021508
CHMP5	-0.021425
TMEM50B	0.021385
EEF1B2	0.021320
ELP2	0.021201
MIF	0.021175
APLP1	0.021166
PSMB5	0.021131
NDUFB2	-0.021108
FUCA1	-0.021087
RPL24	-0.020969
PHGDH	0.020952
ABR	0.020849
APP	0.020844
PPP1R1B	-0.020792
UQCRB	0.020785
TRIM8	0.020757
PPP3R1	0.020672
NPY	-0.020648
IGFBP7	-0.020634
PEBP1	0.020624
TUBA1A	-0.020524
HNRNPU	0.020486
ATP6V0D1	0.020451
ADRA1B	0.020410
PLEKHB2	0.020408
SWI5	0.020339
GDA	-0.020199
FABP7	-0.020187
SIRPA	-0.020157
GSTM5	-0.020136
NDUFA12	0.020104
ALDOC	0.020070
EIF4H	-0.020044
COX4I1	0.020017
SERINC1	0.019998
DBI	0.019971
SLC25A4	-0.019936
TMEFF2	-0.019925
GNAI2	-0.019853
MRPL48	0.019747
SCN3B	-0.019708
PENK	-0.019687
EMC2	0.019682
NDUFB11	-0.019664
C1QBP	-0.019577
CMC1	-0.019442
YWHAH	0.019314
EVL	0.019247
CNOT8	-0.019058
SV2B	0.019033
ANKRD46	0.019010
CDK5R2	-0.018874
GJA1	-0.018823
RPS29	0.018681
NSMF	0.018630
HTRA1	-0.018549
SEC62	-0.018526
TMX2	0.018502
CD47	0.018471
PTTG1IP	-0.018458
ARHGDIG	0.018444
RGS2	-0.018424
TTC9B	-0.018417
MAP1LC3A	0.018391
OGN	-0.018305
DYNC1LI2	0.018298
CD63	-0.018288
COQ10B	-0.018248
RAB28	-0.018195
NOV	-0.018165
PABPN1	0.018087
ASPHD2	-0.018038
AARS	0.018025
ABHD14B	-0.017958
ATP5G1	0.017911
LAMP1	-0.017799
VDAC1	0.017796
CETN2	0.017735
DENND5A	-0.017685
LSM12	-0.017614
NMU	-0.017593
PSMC4	0.017558
PRR7	-0.017507
CCT2	0.017502
NNAT	0.017469
PDPN	-0.017443
TM2D1	-0.017392
LAPTM4A	0.017332
SCG5	0.017189
NPM1	0.017167
GSTM2	0.016971
EGR1	-0.016947
TUBB2A	0.016930
ATP1A2	0.016911
ARPC5	-0.016858
BNIP3	-0.016850
HSPA5	0.016839
MYO6	-0.016817
GJB6	-0.016722
OCIAD1	0.016694
DNAJA2	0.016692
TMED2	-0.016661
ASAH1	-0.016626
MAP2K1	-0.016521
DNAJA1	0.016517
ACOT13	-0.016476
CAB39	0.016467
MGAT4B	-0.016433
TESC	-0.016412
ATG9A	0.016348
ALCAM	-0.016305
CCDC104	0.016224
SOD1	0.016140
TMED9	0.016119
PDCD6	-0.016072
KIDINS220	0.016026
RTP4	0.015858
THY1	0.015839
RPN2	0.015823
RND2	0.015815
HINT2	-0.015800
RNF10	0.015771
FNTA	-0.015764
NPC2	0.015732
CCDC47	0.015616
TMCO1	0.015615
SMC1A	0.015612
CAMK2B	-0.015568
PBX3	-0.015564
SEPT8	-0.015544
RPL36AL	0.015451
MDH2	0.015403
FSTL1	-0.015370
HN1	-0.015365
IGSF1	-0.015360
BAIAP2	-0.015355
ISCU	-0.015351
FBXL5	-0.015347
GLTSCR2	-0.015335
TRAK1	0.015310
CALB2	0.015226
ARHGDIA	0.015194
C1QTNF4	-0.015188
PPP2R5E	-0.015155
AP1M1	0.015112
KIF3C	0.015111
RABAC1	0.015032
SLC12A5	0.014962
FCHSD2	-0.014959
GRINA	0.014956
NCALD	-0.014896
CADPS	0.014854
TMEM248	-0.014852
SLC1A3	0.014780
CLDN5	0.014744
RALA	-0.014726
CCNDBP1	-0.014664
TMEM55B	-0.014635
EPHA4	0.014617
CAMK2G	-0.014612
PRKCG	0.014598
STIM1	-0.014527
ATP5D	-0.014463
SPINT2	0.014446
ITM2A	-0.014442
APOE	-0.014415
CYB561	0.014408
MRPS36	-0.014386
SLC6A3	-0.014373
ABHD3	0.014357
SMPDL3A	-0.014286
ATP2B3	-0.014253
SUMO3	0.014221
TM2D3	-0.014210
SYNPO2	0.014136
PPA1	-0.014059
PRPH	0.014056
SEC11C	-0.014026
CDIPT	-0.014024
RAN	0.013957
GABBR1	0.013939
LCMT1	-0.013894
PSAP	0.013888
PCSK1N	0.013871
LPAR1	-0.013868
COX7A2L	0.013797
PRPF19	0.013790
HSD17B11	-0.013776
RARRES2	-0.013759
SCRT1	0.013730
KRTCAP2	-0.013703
SRP14	0.013694
FBLN1	-0.013691
BRINP1	0.013688
PURB	0.013677
CCNH	-0.013664
MRPS14	-0.013579
SCPEP1	-0.013572
CTGF	-0.013522
VPS28	0.013510
CALB1	-0.013464
C1QB	-0.013398
ARPC2	0.013325
CBR1	0.013310
NUCB1	0.013266
RASD2	-0.013248
PRDX6	0.013243
TRAPPC4	0.013200
PRDX1	0.013187
PPP1R14B	-0.013153
CHGB	0.013152
STUB1	-0.013106
SST	-0.013104
ADSS	-0.013097
PIGS	-0.013092