!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	mouse
!drug_name	Carbidopa
!smiles	NN[C@](C(=O)O)(Cc1ccc(c(c1)O)O)C.O
!drugbank_id	DB00190
!cell_type	jeujunum
!organism	mouse
!end_metadata
CYP2C18	-0.133324
LCN2	0.117764
HP	0.113162
FKBP5	0.106233
SAA1	0.101951
HPX	0.098652
MAT1A	0.094276
CA3	-0.090981
AHSG	0.089007
DIO1	-0.088693
LRG1	0.084099
REG3A	0.080532
FGL1	0.078411
CCL24	-0.076140
FGB	0.075861
TAT	0.075716
TF	0.074461
CP	0.073824
APCS	0.070858
FGG	0.070730
GC	0.070271
BHMT	0.068098
ITIH3	0.067227
SGK1	0.066559
CYP1A1	-0.066342
PDK4	0.064560
CLU	0.063025
ALB	0.061323
HMGCS2	0.060992
IDO1	-0.060427
ZBTB16	0.059886
CUBN	-0.059599
REG3G	0.058851
ANGPTL4	0.058430
PCK1	0.058040
CYP2C9	-0.057530
VTN	0.056133
CXCL13	0.055618
TMIGD1	0.055426
ITIH4	0.054783
DDAH1	0.054337
C3	0.053434
ALDOC	0.053130
DUSP6	-0.052789
KNG1	0.051871
ARG1	0.049925
CYP7A1	0.049874
FETUB	0.048921
ITIH2	0.048866
ACSF2	-0.048453
ACOX2	0.048278
CYP4A11	0.047991
STEAP4	0.047490
UGT2B17	-0.047326
F2	0.047202
ADIPOQ	-0.047068
PTK6	0.046841
IFIT1B	-0.046449
IFIT3	-0.045387
APOH	0.044748
SRD5A2	0.044315
AMBP	0.044220
SPP1	0.044064
CYP2E1	0.043744
TTPA	0.043232
SLC38A4	0.042890
RBP4	0.042634
CYP51A1	0.042419
SLC39A4	-0.042412
SLC47A1	0.042352
PLG	0.041791
LDLR	0.041206
ABCA1	-0.040927
CNN1	-0.040189
IL33	-0.040110
AZGP1	0.039649
CYP2B6	-0.039302
DDX60	-0.039193
TIFA	0.039042
ROS1	-0.038923
DDIT4	0.038902
CFI	0.038874
CES1	0.038619
MYL9	-0.038536
FDPS	0.038410
CFD	-0.038242
TMEM171	-0.038122
SLC6A3	0.037753
PCP4	-0.037745
KDELR3	-0.037537
INMT	-0.037441
ACOT2	0.036987
TDO2	0.036729
FDFT1	0.036590
HSD17B2	-0.036430
CASP3	-0.036324
APOF	0.036231
NDRG1	0.036208
RBP7	-0.036186
APOA5	0.035942
GUCA2A	0.035908
CPNE2	-0.035877
ZBP1	-0.035672
SERPINA3	0.035640
OGN	-0.035554
ISG15	-0.035529
MCOLN3	-0.035522
ACTG2	-0.035410
GZMA	-0.035209
INSIG1	0.035077
SQLE	0.034939
CYP4B1	0.034933
CPB2	0.034617
CHST4	0.034497
ANGPTL3	0.034482
TSC22D3	0.034459
PER1	0.034227
LBP	0.034149
CYP2U1	-0.034031
LSS	0.033981
HSD17B6	-0.033950
MSMO1	0.033803
DES	-0.033749
DNASE1	-0.033585
HERC6	-0.033493
GCLC	0.033399
SLC34A2	-0.033245
DMGDH	0.033234
LCAT	0.032836
TNS4	-0.032743
IGFBP1	0.032368
PPARD	-0.032344
SLC38A3	0.032273
ABCB4	0.032233
HSD17B13	0.031982
FUT4	0.031964
PEX11A	0.031932
AP1S3	-0.031921
CFH	0.031860
SERPINF2	0.031560
MGST1	0.031559
LAMA3	-0.031523
ALPK1	0.031504
FGA	0.031484
APLP1	-0.031397
STARD5	0.031228
SLC19A3	0.031164
HMGCS1	0.031078
ABCB11	0.031072
IAPP	-0.031043
SERPINC1	0.031031
RGS5	-0.030988
DHCR24	0.030910
ASPA	-0.030885
ABCG8	-0.030746
CEBPD	0.030727
S100G	-0.030519
MEP1A	-0.030508
PILRB	-0.030437
GSDMC	-0.030383
MMP7	0.030333
CEACAM20	-0.030166
C5	0.029996
PON1	0.029814
USP18	-0.029723
HPD	0.029684
GBP2	-0.029483
OAS3	-0.029144
NUAK2	-0.028928
NR1H4	0.028813
NPL	0.028792
SLC39A8	0.028782
CA2	-0.028650
CLEC6A	-0.028556
ACTA2	-0.028485
PMVK	0.028362
GADD45G	0.028262
NKG7	-0.028191
RBM3	0.028179
CRP	0.028133
HSD17B7	0.028127
ASNS	0.028102
G6PC	0.028086
CST6	-0.028079
OCM	-0.028022
MYH11	-0.028017
NRN1	0.027968
HTR2B	-0.027960
CPE	-0.027933
ATP8A1	0.027713
ADAMTS1	0.027703
TMEM86B	-0.027618
ALPI	-0.027387
IGFBP6	-0.027321
ABCG5	-0.027283
ASPN	-0.027232
IL2RG	-0.027201
MVK	0.027144
AGTPBP1	0.027138
NUDT5	-0.027130
GBP4	-0.027096
UPB1	0.027040
CLDN4	-0.026973
C5orf28	0.026945
CDC14A	-0.026868
ATF3	-0.026863
MS4A7	-0.026777
ASB2	-0.026761
SPTSSB	0.026738
CA4	0.026641
GLUD1	0.026633
AKR1D1	0.026604
CLEC4M	-0.026587
TBC1D31	-0.026428
ARRDC3	0.026267
C6orf222	-0.026249
CD5L	0.026134
RORC	0.026058
SLC14A1	-0.026030
NSDHL	0.026026
HLA-DQB1	-0.025898
SESN1	-0.025870
ACAA2	0.025861
RTP4	-0.025847
FLVCR2	0.025792
PSMB8	-0.025728
HMOX1	0.025676
SLC46A1	-0.025610
TAGLN	-0.025527
PILRA	-0.025516
ST3GAL4	-0.025462
HBEGF	-0.025455
GNMT	0.025379
RNF186	-0.025276
EPAS1	0.025261
CD3D	-0.025260
EFEMP1	-0.025145
GRAMD2	0.025114
LAMB3	0.024980
TSPAN2	-0.024979
TNC	-0.024943
SLC13A2	0.024796
IP6K2	0.024794
HSD3B1	0.024759
BMP8A	-0.024743
SYNM	-0.024681
IDI1	0.024575
THRSP	-0.024414
ADORA2B	-0.024404
PLSCR1	0.024404
PSMB10	-0.024242
RETN	-0.024241
PLEKHH1	0.024213
GML	0.024182
BST1	-0.024147
MAPK6	0.024146
SERPINA1	0.024141
CD163	0.024135
FMO3	0.024068
MARC1	0.024047
DGKB	-0.024045
SPRYD7	-0.023985
BAAT	0.023938
N4BP2L1	0.023933
FMO2	0.023923
ABCA6	0.023838
IGJ	-0.023813
HIST1H2BI	-0.023795
HLA-E	-0.023757
TFCP2L1	0.023723
TMEM37	0.023710
CHRM2	-0.023705
SAA2-SAA4	0.023692
PTN	-0.023664
TINAG	-0.023634
VSIG4	0.023591
TTR	0.023589
CAP2	-0.023469
CASP1	-0.023451
UPP1	-0.023428
PAH	0.023427
APOA2	0.023414
MKNK2	0.023396
ECI2	0.023371
ALDH1L1	0.023363
FBLN1	-0.023322
GSTA3	0.023243
CDO1	0.023216
ANXA4	-0.023183
PLCE1	0.023156
ATP2B4	-0.023132
TLCD2	-0.023019
EEPD1	-0.022976
LONRF3	0.022973
CLEC7A	-0.022911
SLC25A47	0.022909
LGALS1	-0.022898
NPC1L1	-0.022840
EID3	0.022745
CRY2	0.022738
IFI44	-0.022723
AQP9	0.022700
ETNK2	0.022697
KMO	0.022687
MSS51	0.022666
ENPP7	-0.022637
C17orf78	-0.022600
GPT2	0.022594
MYC	0.022583
ALDH18A1	-0.022573
SLC9A2	-0.022559
CPN1	0.022523
CAV1	-0.022407
MMP9	-0.022386
NR0B2	-0.022376
MFGE8	0.022375
CD3G	-0.022361
OCIAD2	0.022295
PNLIPRP2	0.022271
FHL5	0.022226
SLC10A2	0.022218
SQRDL	0.022008
QPCT	-0.021925
ZFAND2A	-0.021920
GCNT3	0.021897
SYNPO2	-0.021890
MMRN1	0.021831
PLEKHA1	-0.021800
GPR133	0.021732
OR6C3	0.021704
CEMIP	0.021698
DHX58	-0.021681
SLC10A1	0.021679
MAGED2	-0.021672
HLA-DRB5	-0.021660
SERPINA7	0.021647
CD74	-0.021640
MVD	0.021617
RMDN3	-0.021613
AKR1B10	0.021603
PAQR9	-0.021586
SLC20A1	-0.021532
NTS	-0.021476
SLC7A2	0.021393
HSPB6	-0.021295
STAT1	-0.021272
CERS4	0.021245
AASS	0.021233
EXOC3L4	-0.021204
FAM133B	0.021167
GPRC5A	-0.021147
SLC35E3	0.021091
ME1	0.021084
BHMT2	0.021074
RGS13	0.021038
PANK3	0.021011
SLC19A2	0.020991
SLC24A3	-0.020974
OAT	-0.020974
GRAMD3	-0.020968
FLNA	-0.020885
CDC37L1	0.020855
PTPRH	-0.020853
HLA-DMA	-0.020824
GPR17	-0.020761
MECOM	0.020737
TLR3	-0.020728
ACY1	0.020699
ANTXR2	-0.020676
MLKL	-0.020671
STAT4	-0.020659
RHOBTB1	0.020590
IL13RA1	-0.020578
GREB1	-0.020564
HGD	0.020556
POSTN	-0.020539
AGXT2	0.020507
DMPK	-0.020487
ACSS1	0.020476
SPATS2L	-0.020474
UBE2L6	-0.020413
SCPEP1	0.020174
SST	-0.020145
DNAJB9	-0.020122
HMGCR	0.020097
SLC6A6	0.020007
LEAP2	-0.019995
RAB30	-0.019990
NCKAP5	0.019982
IGSF23	-0.019965
CD96	-0.019954
SLITRK6	-0.019923
AACS	0.019902
DDC	-0.019882
FAR2	-0.019839
ITGA8	-0.019831
CCL5	-0.019796
ACAT2	0.019787
GIMAP4	-0.019739
CENPQ	-0.019723
HLA-DQA1	-0.019718
SYT12	-0.019627
REC8	-0.019603
CPED1	-0.019602
HAL	0.019582
AHCY	0.019575
VIP	0.019553
BATF2	-0.019515
SREBF2	0.019499
THEM6	0.019480
TRIM38	-0.019462
GBP7	-0.019409
SDCBP2	-0.019407
ST3GAL5	0.019395
CXCL14	-0.019390
RNF167	-0.019345
PARP14	-0.019343
MFSD4	-0.019332
LAG3	-0.019303
CD101	-0.019263
PSMB9	-0.019207
ENTPD5	-0.019206
PAPPA	0.019179
XKR9	-0.019172
RASGEF1B	-0.019158
NAMPT	0.019135
AVPR1A	0.019093
SLC6A13	0.019088
MFSD2A	0.019054
FHL2	0.019041
SH2D7	0.019031
ELTD1	0.019008
INPP5B	0.018986
TM4SF4	0.018943
FAM111A	-0.018929
MMP13	-0.018895
FABP4	-0.018815
FBXO25	-0.018811
PALLD	-0.018775
ELOVL2	0.018773
LY96	-0.018715
SEMA7A	-0.018696
DAP	-0.018687
NAT8	0.018657
FABP6	0.018648
HEBP1	0.018647
SUSD2	0.018642
GGH	-0.018617
NKAIN1	0.018607
SAMHD1	-0.018606
BTG2	0.018582
ANGPTL7	0.018579
AAMDC	-0.018578
ERRFI1	0.018578
CSRP1	-0.018541
TSPAN4	0.018488
FASN	0.018475
ANKRD37	-0.018468
GFRA1	0.018455
PLA2G2D	-0.018447
AREG	-0.018440
ACVR1C	-0.018408
GPR155	-0.018323
SLC30A4	0.018316
SPARCL1	-0.018300
LAMC2	0.018291
SLC7A5	0.018252
SUGCT	0.018246
TNFSF13B	-0.018238
POLR3G	0.018226
HPGD	0.018188
CHID1	-0.018176
AQP4	0.018176
SFRP5	-0.018139
COLEC10	-0.018132
PXMP4	0.018121
C10orf128	-0.018087
FAH	0.018083
HAUS7	0.018078
SLC13A1	0.018041
DGKD	-0.017998
CASQ2	-0.017996
ABHD3	-0.017983
RNF213	-0.017930
C1orf100	-0.017925
EPHX1	-0.017874
STAP1	-0.017873
BNIP3	0.017869
SAMD9L	-0.017828
PCDHB1	-0.017823
SLC15A2	0.017813
IL1RL1	-0.017789
TFR2	0.017786
PIM1	-0.017768
MMP10	-0.017727
HTRA1	-0.017711
OSGIN1	-0.017710
ACADL	0.017708
ISX	0.017702
LPL	-0.017700