!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	mouse
!drug_name	phorbol ester 12-O-tetradecanoylphorbol-13-acetate (TPA)
!smiles	CCCCCCCCCCCCCC(=O)OC1C(C2(C(C=C(CC3(C2C=C(C3=O)C)O)CO)C4C1(C4(C)C)OC(=O)C)O)C
!pubchem_cid	27924
!cell_type	dorsal skin
!organism	mouse
!end_metadata
S100A9	-0.077518
S100A8	-0.076370
CXCL3	-0.074064
LCN2	-0.069046
ACTC1	0.066527
EPGN	-0.064097
CA4	-0.063206
IL6	-0.061849
IL1B	-0.060588
KRT77	0.057307
SPP1	-0.056495
CLEC4E	-0.055293
IL33	-0.055100
PRSS35	0.054397
SAA1	-0.053914
CCL3L3	-0.053634
CXCR2	-0.051877
KRT16	-0.051272
PTGS2	-0.050231
ASPN	0.049902
KRTAP15-1	-0.048399
IL24	-0.048390
MMP8	-0.048309
IRG1	-0.047589
ZBTB16	0.047524
TREM1	-0.047295
SLC7A11	-0.047224
SFRP2	0.047108
CXCL13	-0.046880
CD14	-0.045362
ANKRD2	-0.045290
PDK4	0.044579
FPR1	-0.043264
HDC	-0.043228
SEMA3D	0.041528
PTPRZ1	-0.041229
CLEC4D	-0.040322
ITGBL1	0.040271
CHI3L1	-0.040258
HMGCS2	0.039890
CCR1	-0.039665
NLRP3	-0.039224
SERPINE1	-0.039017
IL19	-0.038898
CCNB1IP1	-0.038630
SELP	-0.038370
MMP12	0.038097
SLPI	-0.038087
SLURP1	0.038080
PLA2G4E	-0.038055
LAMC2	-0.037569
BCL2L15	-0.037100
TNFAIP6	-0.037069
MYH3	0.036770
KRT6B	-0.036638
CYP7B1	-0.036633
CSF3R	-0.036589
TIMP1	-0.036105
OGN	0.036030
EFHD1	0.036027
CXCL6	-0.035652
CCL13	-0.035407
PILRA	-0.035182
CDHR1	-0.035177
HLA-DQA1	0.034614
SERPINB4	-0.034237
UCP3	0.034127
MYL4	0.034084
C1QTNF3	0.034051
TSLP	-0.034005
PTX3	-0.033720
SERPINA12	0.033709
MFAP2	0.033649
AREG	-0.033526
AKR1B10	-0.033504
ATP6V0D2	0.033479
LRRC17	0.033242
NREP	0.033034
PLAUR	-0.032960
BBOX1	0.032829
SOCS3	-0.032636
PDPN	-0.032600
FMO2	0.032586
SAMSN1	-0.032567
SLC16A3	-0.032565
TXNIP	0.032078
DKKL1	0.032028
IGF2	0.031650
CLCF1	-0.031531
CD72	0.031427
BCL3	-0.031400
ITGA3	-0.031360
TNC	-0.031312
HLA-DRA	0.031299
ECM2	0.031272
THBS1	-0.031231
CTHRC1	0.031228
UPP1	-0.031163
AQP3	-0.031149
IL4R	-0.031006
PI15	-0.030988
LTB4R	-0.030876
KLK13	-0.030863
CPZ	0.030475
ETV4	-0.030419
FGF23	-0.030301
HP	-0.030145
SELL	-0.030032
FGF7	-0.030020
SLAMF7	0.030009
KDELR3	0.029998
DSG3	-0.029823
MFAP5	0.029563
NUAK1	0.029466
ISLR	0.029286
TNNI1	0.029280
HBEGF	-0.029175
OSM	-0.029174
KLK6	-0.028980
LRG1	-0.028895
TSC22D3	0.028723
DAPL1	0.028666
MCOLN2	-0.028649
LRRC15	0.028468
ODC1	-0.028402
TIMM8A	-0.028397
IGFBP6	0.027839
ITM2A	0.027818
TARM1	-0.027803
XKRX	0.027689
P2RY4	0.027667
TNMD	0.027661
HSPD1	-0.027659
DUOX1	-0.027429
CYP27A1	0.027421
NGF	-0.027411
SLC26A7	0.027359
PTGES	-0.027318
STC1	-0.027271
SLC2A3	-0.027172
COL14A1	0.027145
STOM	-0.027132
MRTO4	-0.027117
CD74	0.027039
FN1	0.026919
COL1A2	0.026823
STEAP4	-0.026801
MAMDC2	0.026722
KRT15	0.026719
HLA-DRB5	0.026705
ADM	-0.026693
ITIH5	0.026657
COL1A1	0.026550
MCM3	-0.026432
TNNC1	0.026320
CCL4	-0.026293
SERPINB2	-0.026072
ANGPTL1	0.026064
WNT2	0.026004
PHLDA1	-0.025944
CYP4F2	-0.025884
CCDC80	0.025776
SEC14L2	-0.025695
HIST1H2AD	-0.025681
SLFN12L	-0.025649
TP53INP1	0.025637
HCAR2	-0.025589
KPRP	0.025526
C19orf59	-0.025453
SH2D5	-0.025430
COL3A1	0.025395
PDGFRL	0.025393
TPX2	-0.025198
DUSP6	-0.025189
NOVA1	0.025057
JUNB	-0.024981
PLEK	-0.024782
CLEC12A	0.024751
CDCA8	-0.024655
LDLR	-0.024653
CASQ1	0.024625
DGAT2L6	-0.024603
CDH11	0.024600
THEM5	0.024574
IGSF10	0.024556
OSR2	0.024445
ITPK1	-0.024440
MS4A6A	-0.024436
FKBP7	0.024429
ASF1B	-0.024370
CD34	0.024350
MC5R	0.024314
UBASH3B	-0.024264
SMIM3	-0.024194
LOX	0.024161
STRA6	0.024092
LOC646862	0.024052
SLC39A14	-0.024041
PEG3	0.023979
FAM136A	-0.023950
IER3	-0.023897
TMEM56	-0.023897
SCARA5	0.023833
FBXO32	0.023824
IGFBP5	0.023816
ADAM8	-0.023811
MYOZ1	0.023795
ANKRD1	-0.023790
MCM4	-0.023776
H19	0.023759
KIF4A	-0.023715
ABCA9	0.023697
MYLK2	0.023628
MYL6B	0.023606
NIFK	-0.023563
CES1	0.023460
FABP3	0.023342
HSPE1	-0.023338
RIPK3	-0.023288
CARNS1	0.023261
PDSS1	-0.023247
NOV	0.023237
SOD3	-0.023227
TMPRSS11F	0.023203
COL6A2	0.023142
HSP90AA1	-0.023136
TNF	-0.023110
FGFBP1	-0.023063
HMGB2	-0.023046
RRM2	-0.022983
NOP16	-0.022976
MYH8	0.022963
TMEM8A	-0.022953
CES4A	-0.022938
ALOXE3	0.022931
CEMIP	-0.022897
RPL14	-0.022895
PER1	0.022860
KLK5	0.022793
E2F8	-0.022788
HIST1H2BB	-0.022748
CREB3L1	0.022724
ITGAM	-0.022682
TGM3	-0.022658
SLC24A3	0.022656
SNED1	-0.022643
IL1R1	-0.022634
PPM1G	-0.022632
GLT8D2	0.022543
SLC15A3	-0.022518
RRM1	-0.022481
LRR1	-0.022418
SPINK7	0.022409
RAD51	-0.022375
AVPI1	-0.022348
NHP2	-0.022301
MPHOSPH10	-0.022245
TLR7	0.022196
FSCN1	-0.022187
TARS	-0.022165
C10orf10	0.022066
CEP55	-0.022004
HLA-DQB1	0.021983
FAR1	-0.021962
CLEC3B	0.021952
PPAT	-0.021949
CASP14	0.021946
ACHE	0.021883
CCNB1	-0.021776
MMP13	-0.021749
KRT13	0.021745
SERPINF1	0.021677
SLC6A19	0.021670
MYBPC1	0.021668
CIRH1A	-0.021663
PRND	0.021658
PLK1	-0.021657
RCN3	0.021649
KLF9	0.021640
ABCA5	0.021618
PPIL1	-0.021566
DBF4	-0.021500
ZCCHC5	0.021499
CKS2	-0.021495
NEK6	-0.021494
GREM1	-0.021494
IL12RB2	0.021491
ZNF469	0.021464
RRS1	-0.021458
COL5A2	0.021444
DDX21	-0.021346
ANLN	-0.021338
NOP58	-0.021313
GALNT3	-0.021311
CENPQ	-0.021292
SERPINB1	-0.021257
COX6A2	0.021253
ADAM12	0.021250
AK2	-0.021240
MERTK	0.021237
AURKA	-0.021237
OTOP3	0.021236
GTF2F1	-0.021229
CMSS1	-0.021226
ITGAX	0.021223
ORC1	-0.021222
CRABP2	-0.021217
ASNS	-0.021216
C1QBP	-0.021206
SLC7A5	-0.021194
ARNTL2	-0.021183
HSPH1	-0.021174
SBNO2	-0.021173
PAK6	-0.021161
CAPN6	0.021147
ATP1B4	0.021133
HIF1A	-0.021127
SGOL1	-0.021103
OSMR	-0.021092
C21orf59	-0.021073
LY86	0.021023
NFKBID	-0.021020
SMPD3	0.020997
PCOLCE	0.020989
LAMA2	0.020928
LIG1	-0.020890
TIMM9	-0.020878
THBD	-0.020852
AMPD1	0.020836
EDN1	0.020832
LY9	0.020830
PTTG1	-0.020807
LIPG	-0.020783
LGI2	-0.020779
NUDC	-0.020755
NQO1	-0.020751
TTC27	-0.020731
FAM162A	-0.020727
LYAR	-0.020714
PFKL	-0.020679
SHCBP1	-0.020676
MMP11	0.020668
TREML2	-0.020665
ENO3	0.020664
ITGB4	-0.020649
LUM	0.020599
APOBEC2	0.020545
SMOX	-0.020539
CDK1	-0.020511
SFN	-0.020502
SOSTDC1	0.020456
ACSBG1	0.020437
MTHFD1	-0.020435
MEST	0.020420
KRT78	0.020401
C10orf71	0.020376
CENPN	-0.020368
TIMP3	0.020335
TRIP13	-0.020330
MCM5	-0.020327
AQP9	-0.020319
HPGD	0.020315
CDC20	-0.020289
BTC	0.020262
AGPAT5	0.020260
DIO2	-0.020203
KRT25	-0.020196
TMEM159	0.020194
ID1	-0.020189
C1QTNF6	0.020187
COPZ2	0.020176
CRELD2	-0.020175
TBC1D2	-0.020174
CCDC58	-0.020119
NUP43	-0.020109
S100A6	-0.020086
CPXM1	-0.020037
STX11	-0.020030
NCAM1	0.020030
CYBB	0.020002
ADAMTS14	0.019996
GRIA3	0.019984
MCM8	-0.019974
RPS6KA4	-0.019971
BRIX1	-0.019925
PUS7L	-0.019911
UHRF1	-0.019888
MSR1	-0.019883
POLA1	-0.019845
BIRC5	-0.019844
UCHL5	-0.019843
NMU	0.019837
NCAPG2	-0.019837
GDA	-0.019828
SLC29A2	-0.019816
ATP10B	0.019808
SPARCL1	0.019806
LTB4R2	-0.019806
DPEP1	0.019792
ANGPTL7	0.019772
INCENP	-0.019762
GPNMB	0.019761
MMP19	-0.019759
EIF2S1	-0.019745
SNRPD2	-0.019744
DDX39A	-0.019728
ALOX12	0.019684
TLR1	-0.019663
MPEG1	0.019607
SLC27A3	-0.019600
PLK2	-0.019576
SRM	-0.019534
NOS1	0.019501
ETV5	-0.019487
IFI44	0.019485
CASQ2	0.019481
DKC1	-0.019479
EEF1E1	-0.019461
CPQ	0.019434
MRPL18	-0.019380
TGFB2	0.019362
KLHL38	0.019356
SLC40A1	0.019347
AWAT1	-0.019343
HLA-DMA	0.019318
NID1	0.019316
CTH	-0.019316
CNTFR	-0.019300
KIF24	-0.019292
KPNA2	-0.019279
DGAT1	-0.019276
ELOVL5	0.019264
TMOD4	0.019240
MN1	0.019206
RAD51AP1	-0.019205
CENPM	-0.019180
GLT1D1	-0.019164
PRPF31	-0.019137
IMPDH2	-0.019112
HAUS7	-0.019068
SNRPA1	-0.019061
CXCL12	-0.019054
RGS5	0.019051
CAD	-0.019047
ARHGDIB	-0.019031
MCM2	-0.018991
COL6A3	0.018991
PRSS12	-0.018987
MRPS22	-0.018968
MRGPRX1	0.018952
GSR	-0.018944
CRISPLD2	-0.018936
FAM214A	0.018919
SMYD5	-0.018918
KLF11	0.018905
HELLS	-0.018891
XRCC5	-0.018877
DPT	0.018839
PRIM1	-0.018818
CCT3	-0.018801
ATP1B1	0.018787
SERPINB12	0.018767
GPC6	0.018732
WISP1	0.018704
PFN2	0.018700
AURKB	-0.018676
GNL3	-0.018663
ADAMTS1	-0.018653
PSAT1	-0.018638
PA2G4	-0.018628
FABP5	-0.018601
MB	0.018578
ITGA6	-0.018578
RNASE1	0.018572
SHISA4	0.018555
SMC2	-0.018531
GSG2	-0.018504
NME1	-0.018504
KIAA1524	-0.018487
HARS	-0.018483
ALOX5AP	-0.018482
MYBBP1A	-0.018464
GABRA3	0.018452
NIPSNAP3A	-0.018445
NDC1	-0.018433
CCNA2	-0.018424
KRT4	0.018420
MTBP	-0.018415
COTL1	-0.018406
TSPAN3	-0.018387
CCT5	-0.018361
CCR4	0.018359
FMOD	0.018357
DKK2	0.018348
IL1RL1	-0.018311
HIST1H2BN	-0.018309
LRRC25	-0.018272
MCM7	-0.018271
AKR1C3	0.018271
TICRR	-0.018270