!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!gene	TYK2
!cell	Tcell acute lymphoblastic leukemia cell line
!perturbation	silencing
!disease	leukemia
!end_metadata
IGLL1	-0.130044
RRM2	-0.121247
LAPTM4A	0.120914
RPS25	-0.115742
HMGN2	-0.106740
CHI3L2	-0.105501
CD3G	-0.096726
ADA	-0.090301
MAD2L1	-0.086761
INSIG1	-0.083856
ABCB10	-0.083569
RPL22L1	-0.079866
RPS20	0.079678
TSPAN7	-0.079146
FTH1P5	0.078500
TMA7	0.077890
SELL	-0.075827
RPL24	-0.073068
FTH1	0.066873
RAN	0.066460
USP14	-0.065129
PTP4A2	-0.064673
P2RY8	-0.064095
NPTN	0.064006
IFI16	-0.063693
KARS	-0.063206
FAM217B	-0.062211
ALDH1A2	-0.061320
UBE2C	0.061240
MOB1B	-0.061096
TRMT5	-0.060333
DDX21	-0.059607
ANXA1	-0.059465
DBF4	-0.058250
TNFAIP8	-0.057738
NARS	-0.057055
LAPTM5	-0.056691
DDIT4	-0.055987
MARCKSL1	-0.055929
ITM2A	-0.055795
SLC25A5	-0.055420
IFITM1	0.054550
IGLL3P	-0.054071
SH2D1A	-0.054042
CDK2AP1	0.053751
GBAS	-0.053322
SATB1	-0.053285
RSL24D1	0.052844
LSM6	0.052797
TMSB10	0.052401
NEK7	-0.052332
PFN1	-0.050342
TM7SF3	-0.049246
RPL3	-0.048479
UBC	0.048327
PRC1	0.048264
ITGAE	0.048185
PPIL1	-0.048110
OAZ1	0.047848
BTF3	-0.047761
BEX1	0.047172
ACOT13	-0.046858
MRPL17	-0.046066
COX6C	0.045821
NAP1L1	-0.045341
CBX3	-0.045194
PPA1	-0.045145
ITGA4	-0.044916
ATP5G1	0.044788
CCT3	-0.044457
MRPS27	-0.044350
XPOT	-0.044304
FAM46C	-0.043812
DAD1	0.043762
HADHB	0.043482
PA2G4	-0.043172
KTN1	-0.042844
NEDD8	0.042541
MRPL18	-0.042511
POLR2G	0.042456
MORF4L1	0.042327
CRNDE	0.042252
LANCL1	0.042236
RASGRP1	-0.042227
SH3KBP1	-0.042123
RPS26	0.041855
CDCA7	-0.041847
SUGT1	-0.041841
GLRX	-0.041705
UQCRC2	-0.041548
PAICS	-0.040693
EIF2A	-0.040593
EI24	0.040421
CD3D	-0.040267
CD1E	-0.040154
ATP6V0B	0.040036
PTTG1	0.040029
CSDE1	-0.039836
MSMO1	-0.039767
SERBP1	-0.039727
KIAA0101	-0.039501
SNHG5	-0.039367
GIMAP2	-0.039338
SNRNP25	0.039285
MYB	-0.039254
RPL39L	-0.039220
HMGCS1	-0.039099
TMEM97	-0.038989
SHQ1	-0.038865
CIB1	0.038718
NCK2	0.038481
HMGCR	-0.038346
YBX1	0.038240
GABARAPL2	0.038128
SHFM1	0.038077
PSME2	0.038037
C4orf48	0.038007
EIF3M	-0.037931
NOP56	-0.037826
RPL7L1	-0.037820
ODC1	-0.037759
DERA	0.037744
C14orf119	-0.037728
UQCRFS1	-0.037704
DYNLL1	0.037657
POTEKP	-0.037551
ND2	0.037430
TMEM123	-0.037378
SRP14	0.037368
ATP5J	0.037185
MRPL51	0.037113
NT5C3B	0.036964
AP2S1	0.036872
PFDN4	-0.036734
ATP6V0E2	0.036562
PHB2	-0.036388
WDR12	-0.036108
CD1A	-0.035953
PVRIG	-0.035862
MTCH1	0.035795
TRAC	0.035759
PCBP1	-0.035737
TMEM14C	0.035691
MRPL32	-0.035560
TTC19	-0.035428
ATP5E	0.035352
BCL11B	-0.035121
UQCRQ	0.035109
CREG1	0.035045
RPL36	-0.034990
NPC2	0.034865
SNX3	0.034707
OST4	0.034665
ZWINT	0.034646
ARHGDIB	-0.034002
GLUD1	-0.033987
LTA4H	-0.033888
FAM96A	0.033866
PDLIM1	-0.033840
CDKN1B	-0.033803
ETS1	-0.033721
RPS29	-0.033671
GIMAP7	-0.033565
FDPS	-0.033546
WEE1	0.033438
BLOC1S6	0.033257
XRCC5	-0.033162
SLBP	-0.033091
TOX	-0.033058
IFITM2	0.032996
CALM2	-0.032954
SSRP1	-0.032909
GLUL	-0.032904
GAR1	-0.032870
UQCRH	0.032859
COX8A	0.032851
IARS	-0.032769
GPN1	-0.032728
RB1	0.032673
SUPT16H	-0.032658
ARHGEF6	-0.032457
FABP5	-0.032371
NETO2	-0.032228
IDI1	-0.032189
PPP2CB	0.032185
GLTSCR2	-0.032113
CLTC	0.032052
SUB1	-0.031885
ARL6IP1	0.031830
HNRNPA3	-0.031767
RPL4	-0.031723
OCIAD2	0.031619
FKBP1A	-0.031613
CNBP	-0.031597
NOP58	-0.031591
NDUFA8	0.031548
CSNK2B	-0.031528
MYC	-0.031512
SASH3	-0.031469
TMEM261	0.031469
HENMT1	-0.031357
KIF5B	0.031344
AK3	0.031101
ZNF22	-0.030917
NXN	0.030908
ATP1B3	-0.030903
PTTG1IP	0.030879
ERH	0.030772
BRI3BP	-0.030704
PRPF38A	-0.030603
LEF1	-0.030587
VOPP1	0.030569
CTSG	-0.030512
ADD3	0.030440
MIEN1	0.030365
RPL39	0.030329
BCAP31	0.030285
LRRC47	-0.030237
COX6B1	0.030197
NUSAP1	0.030112
EDEM1	-0.030069
FDFT1	-0.030006
IMPA1	0.029949
COX1	0.029948
PDIA4	-0.029938
IRAK1	0.029872
MIR663AHG	0.029780
B2M	0.029762
UCHL3	-0.029759
NPM3	-0.029704
CD1C	-0.029652
SNHG8	-0.029647
SNRPD2	0.029641
TMX1	-0.029598
VDAC1	-0.029503
SLC25A6	-0.029483
PKIG	0.029435
CACYBP	-0.029424
ARF4	0.029415
TMEM128	0.029393
YWHAQ	0.029268
PRKCH	-0.029207
RPL10A	-0.029104
DDX39A	-0.028997
SRP72	-0.028996
MID1IP1	-0.028808
IGFBP2	-0.028640
NDUFB11	0.028488
BOLA3	0.028487
TRMT6	0.028456
RPL32	0.028379
VAMP7	-0.028373
RASA1	0.028349
PTGES3	0.028282
NDUFA1	0.028147
MRPL47	-0.028120
CCNC	-0.028085
PXYLP1	-0.028071
EIF3D	-0.028022
HSP90AB1	-0.028021
ENO1	-0.027997
GMFB	-0.027973
ALDOA	-0.027934
CYFIP2	0.027821
MRPL33	0.027789
KRT10	0.027751
CCNB1IP1	-0.027716
SLC39A10	-0.027627
NDUFB2	0.027619
TMEM258	-0.027611
ALYREF	-0.027558
DDX24	-0.027540
C6orf48	-0.027500
HLTF	-0.027488
ATXN1L	0.027468
GNA15	-0.027403
NOP10	0.027386
H2AFZ	0.027366
SMIM15	-0.027201
COX7C	0.027146
SEPT6	-0.027093
RPL30	0.027082
ORC6	0.027044
SPCS1	-0.027043
NUCKS1	0.026988
MYL6B	0.026942
ATP5C1	-0.026920
RABGGTB	-0.026909
MRPL24	-0.026834
DNTT	-0.026831
TSTD1	0.026826
MALAT1	0.026817
HMGB3	0.026815
HCLS1	0.026790
TOP2A	0.026771
RPL6	0.026667
TOMM5	-0.026624
ID3	0.026607
HSBP1	0.026570
SIX6	-0.026536
PABPC3	-0.026534
ATP6V0E1	0.026531
ELMO1	-0.026528
GPX4	0.026463
C18orf32	0.026361
ICT1	0.026318
CD1B	-0.026294
EIF4G2	-0.026290
FEN1	-0.026253
FBL	-0.026216
PLAC8	-0.026193
HMGN4	-0.026075
RRP1B	-0.026074
TOP2B	0.026062
SMCO4	-0.026053
ATP6V1F	0.026050
IMPDH2	-0.025969
PRR13	-0.025968
PSMB1	0.025949
ZFP36L2	-0.025932
AUP1	-0.025929
HSPA8	-0.025916
MYL6	0.025886
FAM96B	0.025862
RBBP7	-0.025859
CRLF3	-0.025813
FAU	0.025802
SEH1L	-0.025756
RPL29	-0.025664
COX5B	0.025615
LAMP3	-0.025567
TDP2	-0.025557
CTPS1	-0.025545
WDR82	-0.025502
PPT1	-0.025470
WASF1	0.025468
MRFAP1	0.025365
PPIB	0.025302
SHISA2	-0.025296
EMG1	-0.025234
NMI	-0.025199
FGD5-AS1	-0.025190
COPS5	-0.025189
ACADM	-0.025189
BLOC1S2	0.025152
PSMD10	0.025142
MAK16	-0.025111
CCNB1	-0.025091
EEF2	-0.025088
TUBA1A	0.025027
RAD23A	-0.024954
CCT6A	-0.024945
PNRC2	-0.024884
SNHG15	-0.024849
TAF1D	-0.024764
ATP5I	0.024750
EIF3E	-0.024729
CHST11	-0.024722
TXNL4A	0.024684
PXDN	0.024662
COX7A2	-0.024548
EEF1B2	-0.024534
NDUFA11	0.024521
MEA1	0.024498
ZNRD1	-0.024341
AMD1	-0.024330
AIDA	0.024314
MTHFD2	0.024286
PARK7	0.024280
HMGB1	0.024257
UBP1	0.024245
PTPRCAP	-0.024224
DENND5A	0.024220
VAMP3	0.024208
HOXA7	0.024204
RFK	-0.024129
CD2	-0.024126
LOC100506844	0.024120
RPL8	0.023945
ARCN1	-0.023930
DDX6	0.023900
ANP32B	0.023890
TRAPPC5	-0.023871
ACAT2	-0.023862
RAC1	0.023818
NKX3-1	-0.023738
UBE2K	0.023737
YIF1A	-0.023684
VPS29	-0.023639
BCAT1	-0.023577
TOP1	-0.023551
GNL3	-0.023547
SCP2	0.023519
EFEMP1	-0.023489
NSA2	-0.023487
KDELR2	0.023449
TMED8	-0.023442
FTL	0.023416
ITM2B	0.023402
GRB2	0.023355
SLC25A15	-0.023350
KIF20A	0.023343
C11orf48	0.023292
FYB	-0.023139
GARS	-0.023135
LBR	-0.023110
SEP15	-0.023108
ATP5H	0.023099
HSPB11	0.023026
VRK1	-0.022999
ZNF367	0.022931
DYNC1I2	0.022908
RPL12	-0.022895
SSR2	0.022816
PHF5A	-0.022812
UBA2	0.022747
POLR1D	-0.022745
PTPLAD1	0.022588
DYNLT1	0.022570
RWDD4	-0.022561
NDUFA4	0.022522
POLB	0.022504
SQLE	-0.022502
IQGAP2	-0.022495
UBA52	0.022480
TNFSF4	-0.022460
TMEM14B	0.022388
PSMC1	0.022325
GLRX5	0.022311
AKR1B1	-0.022188
NDUFB9	0.022160
C15orf61	-0.022150
CHP1	0.022112
SUMO1	0.022106
BUB3	0.022092
UFC1	0.022037
PRPF19	-0.022025
NAE1	-0.022024
RPS27L	0.021996
LAMTOR5	0.021993
NOL11	-0.021948
LDHB	-0.021934
MSL2	-0.021904
UBB	0.021884
EXOSC9	-0.021847
CDIPT	0.021840
PSMD14	0.021776
WDR83OS	0.021770
PELI2	-0.021761
BIRC5	0.021755
LASP1	0.021743
MAPRE1	-0.021725
CLINT1	-0.021714
B4GALT6	-0.021695
EID1	0.021671
YWHAB	0.021608
ARMC10	-0.021607
TMEM106C	0.021602
BNIP2	-0.021574
MT2A	0.021563
PGK1	-0.021540
LMAN1	-0.021463
CDC123	-0.021454
BLCAP	0.021442
SEPT7	0.021434
MINOS1	0.021416
NDC80	0.021386
CECR1	-0.021378
RAP1B	-0.021365
AP3S1	-0.021352
CLNS1A	-0.021318
RPS10	0.021240
RPF2	-0.021237
DSTN	-0.021214
IMMP1L	0.021144
CCNA2	-0.021130
UHRF1	-0.021116
PKD1P1	0.021100
ACTG1	0.021064
LSM1	0.021044
MRPL27	-0.021043
TBCA	-0.021027
FMR1	0.021014
GNPDA1	-0.020974
DENND6A	-0.020971
POLR2J	0.020938
IARS2	0.020909
TBC1D4	-0.020885
PPIA	-0.020884
PSMA5	-0.020878
SUN2	0.020875
PFAS	-0.020871
EIF2D	-0.020870
MYO7B	-0.020851
CHCHD10	-0.020851
CENPW	0.020837
MPHOSPH10	-0.020808
PGAM1	-0.020786
PABPC1	-0.020744
GSTP1	0.020734