!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	mouse
!drug_name	Fasudil
!smiles	C1CNCCN(C1)S(=O)(=O)C2=CC=CC3=C2C=CN=C3
!pubchem_cid	3547
!cell_type	Forebrain astrocytes - 24 Hours
!organism	mouse
!end_metadata
NPVF	0.075582
TAGLN	-0.073760
SCG2	-0.070199
LBP	-0.068454
ESM1	0.063822
MMP3	0.059330
SLC16A4	-0.058167
SLC7A11	0.054691
HSPB6	-0.053821
COL16A1	-0.053350
ACTA2	-0.053147
RNASE1	0.051898
EGR1	-0.051276
KIAA0101	-0.050478
GAD1	0.048208
HMOX1	0.047471
GSTA5	0.047255
CLEC4D	0.046590
ADAMTSL4	-0.046364
SETD7	0.044988
TCEAL5	-0.044635
NEK5	-0.044325
ABHD2	0.044258
UHRF1	-0.044064
TNFRSF12A	-0.043876
GTSE1	0.043529
TNFRSF21	0.042470
ZCCHC12	-0.042384
DYNLRB2	-0.042117
VIT	-0.041908
EDNRA	-0.041729
MCM5	-0.041711
CD82	-0.041706
NRM	-0.041686
DIAPH3	-0.041581
CDKN1A	0.041534
PLEKHA4	-0.040833
HMP19	-0.040391
ASS1	0.040348
HIST1H2AK	0.040191
ESD	0.039919
ZMAT3	0.039885
SLC13A4	0.039836
SPAG6	-0.039676
PRC1	-0.039511
IER3	0.039380
MORN5	-0.039311
RIN1	-0.039131
FAM180A	0.038886
DPYSL3	0.038875
CCNE2	-0.038834
CXCL12	0.038450
ARRDC4	0.038096
EPHB1	0.037850
CHAF1B	-0.037771
ALDH3A1	0.037571
HSPA2	-0.037471
PREPL	-0.037442
GCLM	0.037215
MSRB2	-0.037168
IL18	-0.036899
RBMX	-0.036748
TCEAL6	-0.036704
AAAS	0.036450
SLC1A2	0.036239
SVOP	0.036013
CIB2	-0.035939
REC8	-0.035853
MMD2	-0.035825
SMARCA1	-0.035594
LMOD1	-0.035445
CXCR4	0.035411
NCAN	-0.035408
KIAA1731NL	0.035317
RAB27A	-0.035292
UBA7	-0.035202
TIMP4	0.035066
RAD54B	-0.034942
ANG	0.034847
MDH1B	-0.034832
RBL1	-0.034788
RSAD2	-0.034746
LRRC28	0.034670
CLDN11	0.034456
PLK1	-0.034410
GDF15	0.034159
FABP3	-0.034102
HIST1H2BC	0.034072
CPNE8	0.033877
MPP1	0.033730
TALDO1	0.033623
FIGNL1	-0.033617
SFXN5	-0.033572
SLAMF9	-0.033560
MNS1	-0.033457
PLIN4	-0.033426
KIF22	-0.033323
HDC	-0.033145
ACTB	-0.033094
HTRA1	-0.033053
PBK	-0.033018
PHLDA3	0.033010
FLRT3	0.033000
C15orf48	-0.032879
HIST1H2AG	-0.032838
CMPK2	-0.032822
SERPINF1	-0.032786
GAS7	0.032768
BMP4	0.032734
BTBD11	0.032675
RNFT2	-0.032657
FBXO32	0.032498
GAL3ST1	-0.032386
IGSF9	-0.032346
PRKCDBP	-0.032303
MCM2	-0.032265
PHKG1	-0.032208
P2RY13	-0.032178
DLK1	-0.032127
SLC25A10	-0.032032
NSDHL	-0.032025
TIMP1	-0.031818
MCM10	-0.031771
HIST1H2AA	-0.031590
PTGES3L	-0.031588
RLN1	-0.031587
SLC25A18	-0.031367
DNAJB13	-0.031317
KAZN	0.031292
NUSAP1	-0.031276
RARRES2	-0.031260
EGR2	-0.031253
NCAM1	-0.031215
FAM111A	-0.031193
FSCN2	0.031016
SLC6A15	-0.030950
RSPH1	-0.030910
INSIG1	-0.030904
SLC40A1	0.030840
CSRP2	-0.030818
CCNB1	-0.030813
CENPA	-0.030809
TP53INP1	0.030666
SLC6A17	-0.030640
ANLN	-0.030558
KNDC1	-0.030530
ADM	0.030471
CDCA3	-0.030449
RUFY3	-0.030377
ST6GALNAC5	0.030375
TGFB2	0.030358
C2orf76	0.030341
IRGM	-0.030289
HEG1	0.030248
AARD	-0.030210
MCM7	-0.030149
ELMO3	-0.030125
BIRC5	-0.029996
GPER1	-0.029981
CBR3	0.029968
SEL1L3	0.029961
ACTG1	-0.029758
AKAP14	-0.029745
SOAT1	-0.029730
AURKA	-0.029726
HIST1H2AM	-0.029697
UAP1L1	-0.029670
BTBD6	-0.029558
TSC22D1	0.029451
LIX1	-0.029407
RDH5	-0.029391
TOP2A	-0.029376
TMEM43	0.029368
SLC39A12	-0.029219
CCDC113	-0.029139
PTPLAD2	-0.029079
FOLR1	-0.029066
BGN	-0.029050
GPR123	-0.029001
ENKUR	-0.028988
ADORA1	0.028970
LYPD1	0.028892
CP	0.028822
SLC35F3	0.028818
NPY	0.028728
HRASLS	-0.028695
OLFML3	-0.028669
LENG9	-0.028638
HIST1H2AJ	-0.028603
MYL4	-0.028555
CSRNP1	-0.028325
OGFRL1	0.028308
SORBS1	0.028302
PIFO	-0.028293
CCL5	0.028237
C4orf22	-0.028237
FAM115C	-0.028235
SLC2A6	-0.028231
MGST2	0.028120
IQGAP2	-0.028061
CNN2	-0.028039
MMP14	-0.028001
WDR6	-0.027962
LGALS1	-0.027788
NDRG1	0.027661
RAB3D	-0.027585
ENTPD4	-0.027507
HTR2B	0.027459
FST	0.027457
SAC3D1	0.027441
PSRC1	0.027381
MDM2	0.027374
WDFY1	0.027330
SHROOM3	0.027312
RPRM	0.027237
SUCNR1	0.027179
CAPSL	-0.027135
KIRREL	0.027129
WDR16	-0.027019
ITIH3	-0.027000
SLC39A10	0.026992
HDHD3	-0.026897
CHAC1	-0.026886
DIRAS2	0.026850
CYP1B1	0.026771
ZNF365	0.026728
NUDT18	-0.026693
CTF1	-0.026673
WBP1	-0.026615
MMP12	0.026613
CDCA2	-0.026585
PAM	-0.026564
PARP3	-0.026420
SORBS2	0.026382
ARHGDIG	0.026376
GLRX5	0.026325
MCM3	-0.026303
FHIT	-0.026264
LOC728392	-0.026224
NOD1	-0.026219
REP15	0.026202
SLC39A11	-0.026163
CTNNBIP1	0.026111
F13A1	0.026111
TK1	-0.026108
SAMD9L	-0.026103
SKIL	-0.026065
NUPR1	-0.026040
SLC19A2	0.026006
TEKT1	-0.025942
MCM6	-0.025893
IGFBP3	0.025870
HPRT1	0.025836
DFNB31	0.025836
ASAH2	-0.025800
CDCA8	-0.025733
EVA1B	-0.025667
ITGB4	-0.025648
P2RY1	0.025644
SLC7A5	0.025633
CIART	0.025623
PHGDH	-0.025601
CHRNB1	-0.025570
MRPL17	-0.025531
PCOLCE	-0.025455
GAS6	0.025366
UGT1A6	0.025354
KBTBD6	-0.025343
AIF1	-0.025332
SCARA3	-0.025308
PDGFA	0.025294
TOP3B	0.025285
RRM2	-0.025227
BCL2L1	0.025217
BDH2	-0.025204
FLOT1	0.025203
ARNTL	-0.025197
STMN2	0.025185
LRRC48	-0.025177
KIF23	-0.025082
NAT14	-0.025080
UBE2N	0.025070
SNTG2	-0.024987
DNALI1	-0.024958
BCAN	-0.024956
TMEM253	-0.024951
TMEM42	-0.024934
LPL	0.024901
MYL6	-0.024828
NUP210	-0.024747
G6PD	0.024704
SLC6A8	0.024664
NEK6	0.024582
PTK7	0.024578
RPS27L	0.024569
GPC1	0.024510
HIST2H2BF	0.024492
DERA	-0.024486
ATAT1	-0.024431
HIST1H2AH	-0.024307
CDC20	-0.024272
LDOC1L	-0.024270
IL19	0.024243
MAPKAPK3	0.024182
GRHPR	-0.024158
CSF1	-0.024139
ENC1	0.024129
CCL2	-0.024125
TMED10	0.024112
HIST1H4I	0.024094
BRIP1	-0.024092
DUSP4	0.024071
CHODL	0.024063
DNAAF3	-0.023959
DAPK1	0.023954
CX3CL1	-0.023901
MVP	0.023814
SLC2A4	-0.023793
VAT1	0.023767
QPCT	-0.023765
GSTO1	0.023732
SCARF2	-0.023726
MAPT	0.023716
APRT	0.023662
KLF6	0.023623
AS3MT	-0.023623
FSTL1	-0.023599
ADCK4	-0.023584
UBA5	0.023529
ATP13A4	0.023514
IRF2BPL	0.023513
ADD3	0.023467
ZCCHC7	0.023441
HIST1H2AB	-0.023415
HAP1	-0.023392
CEP55	-0.023373
PBXIP1	-0.023369
KIF2C	-0.023358
DYRK3	0.023356
PDRG1	0.023336
MAD2L1	-0.023307
KDM6B	-0.023234
NCAPH	-0.023197
CHST1	-0.023197
PSTPIP1	-0.023179
SHISA4	-0.023160
FAM167A	-0.023117
ANGPTL2	0.023115
LIPA	0.023110
ETV4	0.023107
ATIC	0.023102
PA2G4	0.023020
SGMS1	-0.023001
SLC3A2	0.022999
GRIA1	-0.022988
CLSPN	-0.022985
LGI3	-0.022962
GLB1	-0.022936
PCDHGC3	0.022913
VSTM2B	0.022904
AXL	-0.022899
FCGR2B	0.022865
ADRA2A	-0.022816
LRCH1	0.022816
ACPL2	-0.022805
PPAPDC1B	-0.022800
NUCKS1	0.022793
TRIM11	0.022761
SNRNP70	-0.022753
TARDBP	0.022747
DUSP28	-0.022742
NUTF2	0.022685
FABP5	0.022681
GAMT	-0.022677
LCAT	-0.022640
CD276	-0.022509
NTN3	-0.022508
SULF1	-0.022481
SAT2	-0.022454
TMEM117	-0.022439
POLD1	-0.022398
CDT1	-0.022365
TLR2	-0.022348
PTS	-0.022339
CAT	0.022333
C1QBP	0.022301
SLC8B1	0.022299
STK11	0.022277
RFC5	-0.022266
FGFR1	0.022197
GPX7	-0.022176
SRSF2	-0.022130
SSR4	-0.022118
SAMD5	0.022118
ERCC5	0.022117
BAX	0.022075
BSG	0.022072
OLFM1	0.022065
PAK3	0.022048
TMEM203	-0.022019
HIST1H4L	0.022016
CHAF1A	-0.022012
EIF2AK1	0.021995
HBEGF	-0.021993
COL4A4	0.021990
PTP4A3	0.021918
PLEKHB1	-0.021912
E2F1	-0.021903
SERPINE2	0.021890
GAP43	0.021859
TMEM136	-0.021858
MOB3B	0.021840
ZHX3	-0.021826
ATN1	0.021766
BDNF	0.021753
FLYWCH2	-0.021752
SH3D21	-0.021712
ALDH3B1	-0.021693
MS4A7	0.021687
PHLDA1	0.021686
SALL3	0.021677
SARS	0.021658
PSMC3IP	-0.021649
IVNS1ABP	0.021649
TGM2	-0.021633
BACE1	-0.021625
PCIF1	0.021612
EMC8	0.021585
EEF2	-0.021566
ADAM9	-0.021529
ANXA3	-0.021500
TXNRD1	0.021487
LRRC23	-0.021468
FADD	-0.021459
H2AFX	-0.021391
COPZ2	-0.021384
UACA	-0.021367
SLC25A17	0.021319
SRF	-0.021301
CORO1A	-0.021290
TSPAN9	-0.021255
GLDC	0.021232
SUPT5H	0.021220
CHST2	0.021204
OSR1	0.021179
NIT2	0.021172
SKA3	-0.021146
UBE2E1	0.021127
NSUN4	-0.021106
APOBR	-0.021084
AGAP1	0.021081
FAM216B	-0.021064
ESCO2	-0.021057
SLC7A4	-0.021048
TM7SF2	-0.021046
C3orf67	-0.021033
TUBB6	-0.021011
TMEM44	0.021008
LRP4	-0.020994
PCDHGB2	0.020979
ACP6	0.020967
ASPG	0.020963
CD44	0.020944
TLCD1	-0.020931
PRIMPOL	-0.020928
GNE	0.020915
SOCS2	-0.020914
CASP8	-0.020900
TRAF1	-0.020848
NUDT1	-0.020845
FAM26E	-0.020843
GADD45A	0.020835
TPRN	0.020814
MORN2	-0.020811
PITHD1	0.020806
CTPS1	0.020791
APOBEC1	-0.020780
ATOH8	0.020764
TRPM6	-0.020757
SMOC1	-0.020747
CASK	0.020731
THY1	-0.020726
DYNLL1	-0.020673
LPAR1	0.020667
PDGFRL	-0.020651
SEZ6	0.020642
RAD51C	-0.020626
ZRSR2	0.020598
CTNNBL1	0.020583
SEMA5A	0.020582
C16orf74	0.020572
FAM84A	-0.020568
SAMD14	-0.020556
NSMF	-0.020554
FKBP14	-0.020515
CHST3	-0.020494
TPGS2	-0.020494
PLOD2	0.020456
TRPC7	-0.020455
CDCA7	-0.020435