!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Mus musculus
!ligand_name	17beta-estradiol
!ligand_id	CHEBI:16469
!cell_type	ovarian cancer cells
!organism	mouse
!end_metadata
AKR1C3	0.101368
CYP11A1	0.084483
GPM6A	-0.083959
KCTD14	0.078553
INHA	0.075449
LRRN4	-0.074287
SFRP4	0.072303
UPK3B	-0.071814
MYL7	0.070332
PKHD1L1	-0.067127
GREB1	0.066107
LGALS2	-0.063516
LIPG	0.063208
UPK1B	-0.061851
ENPP2	0.061247
PRSS35	0.060474
FGF7	0.055613
ADM	0.055261
FRZB	0.054254
ARG1	0.053759
ZBTB8B	0.053177
PTGS2	0.052475
MST4	-0.051753
HLA-DQA1	-0.051508
INHBB	0.050870
TMEM86A	0.050202
RERG	0.050000
PGR	0.049889
NR5A1	0.049787
CPA3	-0.049787
CHST11	0.049779
MYOC	-0.049608
SLC16A12	0.049438
HOXD11	0.048438
HOXD13	0.048213
KRT7	-0.047885
CLU	0.047591
MARK1	0.047390
NRN1	0.047180
CLDN15	-0.047094
DPP4	-0.046929
MGARP	0.046245
PADI2	0.045896
RASD1	0.045856
THBS2	0.045593
PRUNE2	0.045552
ERRFI1	0.045390
KRT14	-0.045106
SERINC5	0.045090
MPEG1	-0.044943
HOXD10	0.044924
NT5E	0.044763
TMEM45A	0.044734
BNC1	-0.044439
COL18A1	-0.043807
PRR15	-0.043743
BPIFC	0.043398
ITGA2	0.043277
CD74	-0.043195
PPFIBP2	-0.043180
HLA-DRA	-0.043167
FMOD	-0.043094
KDR	0.042886
CYFIP2	0.042690
APOD	-0.042683
GGT5	0.042649
ACSBG1	0.042262
GPC3	-0.042208
SERPINE2	0.042125
CDH2	0.041884
SPRR1A	0.041856
FAM213A	0.041469
XPNPEP2	-0.041154
EPPIN	0.040919
GDPD3	0.040503
GJA1	0.040478
SLC30A4	0.040432
PRELP	-0.039914
BHLHE40	0.039828
TAF4B	0.039453
ARHGAP42	0.039339
CMBL	-0.039336
AGTR2	0.039329
ME1	0.039100
NKAIN4	-0.039016
EMR1	-0.038966
GCNT1	-0.038323
EDNRA	0.038293
PTPN5	0.038181
ALCAM	-0.037929
B4GALT5	0.037831
RSPO1	-0.037694
ENPP3	0.037566
SLC38A5	0.037457
CA3	-0.037406
SLC25A30	0.036863
CYP2E1	-0.036695
NDNF	0.036638
HSD3B2	0.036600
NETO1	-0.036588
BCAM	-0.036566
DLK1	-0.036533
CYBB	-0.036241
TMTC1	-0.036104
SLC12A2	0.036050
PLAU	0.035958
HLA-DQB1	-0.035950
ITM2A	-0.035922
STC2	0.035904
MS4A7	-0.035807
TGM2	-0.035611
GRIA4	-0.035319
NXPH1	-0.035280
CDON	-0.034887
LY86	-0.034766
ERMP1	0.034740
C10orf82	0.034708
SCARA3	0.034680
VEGFA	0.034612
CCL13	0.034492
KCNAB1	-0.034369
CYP7B1	0.034341
ESM1	0.034264
FDXR	0.034215
CLEC7A	-0.034184
LYZ	-0.034105
FAM110C	0.033929
FBXO32	0.033901
PHLDA1	0.033685
SOAT1	0.033651
PCDH15	-0.033622
PDE3A	-0.033576
STK32A	0.033556
ANO1	-0.033464
SLCO3A1	0.033447
CHCHD10	0.033402
PLXNA4	-0.033322
SMPD3	-0.032986
MSLN	-0.032863
SLC14A1	0.032848
CLDN1	-0.032701
RBMS3	-0.032675
INHBA	0.032463
TMEM255A	0.032442
C9orf152	0.032172
DPT	-0.032145
FMO2	-0.032025
CLEC11A	-0.031876
MESDC1	0.031843
CRIP1	-0.031762
PNLIPRP1	0.031639
GATA4	0.031436
COL3A1	-0.031419
DNAJC6	-0.031380
KIAA0040	0.031340
PTGS1	-0.031300
KANK1	-0.031273
MMP9	0.031232
PAPLN	0.031129
GPX3	0.031126
LAMC2	0.031052
ALDH1A2	0.030943
MFSD2A	0.030854
PDE7B	0.030819
TAGAP	0.030750
CTSV	0.030470
CASQ1	-0.030468
DKK2	0.030432
VLDLR	0.030385
TMTC2	0.030299
APOE	-0.030274
AMMECR1	0.030166
SLC40A1	0.030138
GJB2	0.030122
OSR2	0.029911
ZSWIM7	0.029895
SOCS2	0.029837
HLA-DRB5	-0.029824
SEMA3C	-0.029811
CD48	-0.029770
DCBLD2	0.029767
MAP2K1	0.029738
TUBA8	0.029585
WNT2B	-0.029554
AMHR2	0.029523
STAB1	-0.029523
CFD	-0.029517
EMB	0.029501
C7orf63	0.029456
PANK3	0.029449
SRGAP1	0.029383
GOT1	0.029364
C1QTNF7	0.029343
TWIST2	0.029160
PNLIPRP2	0.029149
MEGF6	-0.029125
ANXA1	-0.029120
SERPINB1	-0.029074
LUM	-0.028999
APOBEC1	-0.028971
ANPEP	-0.028931
C3AR1	-0.028917
FIGF	-0.028886
SGCE	-0.028833
GALNT13	0.028715
TRPC6	0.028698
CFTR	-0.028680
HTRA1	0.028662
EPDR1	0.028654
SP110	-0.028612
C1QC	-0.028498
FAM169A	0.028485
CDH1	-0.028435
PHYHIP	0.028406
TRPC4	0.028365
MS4A4A	-0.028355
LRP2	-0.028337
ABCG1	-0.028295
PCDH19	-0.028234
IDH1	0.028228
PTPRJ	-0.028227
ALDH3A1	0.028173
C1QB	-0.028122
EPB41L4A	-0.028046
PLA2G4A	0.027953
FCGR2B	-0.027918
HPGD	-0.027883
CELA3B	0.027816
SESN3	0.027810
EFEMP1	-0.027793
MED10	0.027790
SMTNL2	-0.027745
NPHS2	0.027728
STK39	-0.027673
DAB2	-0.027625
EGFL6	-0.027439
PVALB	-0.027402
GRAMD1B	0.027388
ENPP1	0.027284
TPBGL	-0.027238
COL4A2	0.027190
CLEC6A	-0.027140
PTPRZ1	-0.027012
NR0B2	0.026900
SCUBE1	0.026874
RDH10	0.026860
ANKRD44	0.026815
ETV6	0.026793
PIM1	0.026781
GUCY1A2	-0.026748
ITGBL1	-0.026747
PKNOX2	0.026720
CHST4	-0.026637
ID2	-0.026612
GPR65	-0.026509
NGFR	0.026306
NSMAF	-0.026283
STAMBPL1	0.026276
SLFN5	-0.026248
LAPTM5	-0.026156
C16orf89	0.025988
MAFB	-0.025951
IGF1	0.025934
RLN1	0.025801
LMCD1	0.025763
GLIS3	0.025682
TCF4	0.025628
FZD2	0.025606
BNIP3	0.025570
TFRC	0.025552
JAM2	0.025427
CSF1R	-0.025396
HPGDS	-0.025389
THSD4	0.025322
SYT9	-0.025309
C1QA	-0.025293
FDFT1	0.025268
MRC1	-0.025266
TMEM47	-0.025230
GADD45G	0.025205
ACSL4	0.025196
CDKN1A	0.025115
TGFB3	-0.025002
PDPN	-0.024982
ZNF705A	-0.024956
FABP4	-0.024949
SDC3	-0.024902
ZNF521	-0.024889
CD93	-0.024874
PRRG3	-0.024811
COL4A1	0.024770
SPINT1	0.024733
G6PD	0.024725
SSFA2	-0.024709
CD82	-0.024707
KCNK1	0.024702
UNC93B1	-0.024696
SLCO2B1	-0.024678
CHRDL2	0.024667
PRKD1	-0.024551
PTPRC	-0.024528
SHROOM3	0.024511
TRIM2	0.024503
ALDOC	0.024486
C15orf26	0.024371
PCOLCE	0.024298
SERTAD4	-0.024286
FAM180A	-0.024214
SEMA3D	-0.024144
CD44	0.024134
SLC4A4	-0.024047
BMP6	0.024031
GRM3	-0.023993
FYB	-0.023954
TLR7	-0.023953
ALAS2	-0.023948
FDX1	0.023946
IL33	-0.023879
PLK2	0.023842
IFI44	-0.023807
ABCA1	-0.023786
FAM49A	-0.023751
TFPI	-0.023738
RGS5	-0.023734
MYO1D	-0.023713
LOXL1	-0.023705
CYTH4	-0.023693
MRO	0.023669
USP3	0.023638
DUSP6	0.023637
MYO1F	-0.023603
EPB41L3	0.023602
IL18	-0.023592
BOC	-0.023532
CRYL1	0.023494
SGK1	0.023490
ELMO1	0.023462
SOS2	0.023462
TM4SF5	-0.023451
RPS6KA6	-0.023406
ADAP2	-0.023347
DOC2B	0.023324
TNNC1	0.023306
CYP26A1	0.023268
COLGALT2	0.023267
AMPD3	0.023227
LHFP	0.023168
FGF9	0.023080
RASGRP1	0.023010
STOM	-0.022985
LDLR	0.022984
NCKAP1L	-0.022953
CLYBL	0.022941
MSMO1	0.022906
SULF1	-0.022868
B4GALT6	-0.022831
CTSS	-0.022814
MYH14	0.022797
PFN2	0.022787
DUSP4	0.022764
MET	-0.022759
FOSL2	0.022724
KCNK5	0.022679
MREG	0.022656
BMP2	0.022565
ISLR	-0.022553
PFKL	0.022537
ST3GAL5	0.022509
TRIB2	0.022483
DPYSL3	0.022464
SEMA4A	0.022463
SMIM1	-0.022459
PM20D1	0.022454
CHRNB1	0.022431
MOB3B	0.022392
SAMD9L	-0.022373
RARRES1	0.022363
PHACTR1	0.022342
COL12A1	-0.022336
SLIT2	-0.022306
IFI44L	-0.022291
CRISPLD2	0.022281
MYRF	-0.022242
P2RY13	-0.022199
GALNT16	0.022172
MYLIP	-0.022141
VCAM1	-0.022128
PLD4	-0.022101
SERPINB5	-0.022064
TRIM63	0.022063
SV2A	-0.022056
IL10RA	-0.021971
BTBD3	0.021966
PCNXL2	-0.021963
RASSF2	-0.021956
RASGRP3	0.021935
KRT17	-0.021933
SCIN	0.021927
SLC35G1	0.021888
CPQ	-0.021875
ADAM12	0.021869
CD200	-0.021854
GAREM	0.021848
ARHGEF3	0.021846
ARRB1	-0.021839
CD72	-0.021815
GPAM	0.021740
CTSK	0.021737
INSIG1	0.021716
DCTN6	-0.021660
SVEP1	-0.021637
ABLIM1	-0.021614
ST6GAL1	0.021594
ELAVL2	-0.021520
BGN	-0.021514
GSTA3	0.021473
LTBP4	-0.021459
ADHFE1	0.021436
PIK3AP1	-0.021436
SSR3	0.021384
FAM189A2	0.021351
LCP1	-0.021313
FAM46C	-0.021251
A4GALT	0.021196
GNB4	-0.021163
PARP1	0.021159
RBPMS2	0.021130
FBLN5	-0.021109
RARS	0.021106
GPC6	-0.021087
SPOCK3	0.021045
RBPMS	0.021031
SLC35F2	0.021009
ERO1L	0.020979
LSS	0.020979
MPZL2	-0.020976
CD36	-0.020965
EFNB1	-0.020947
PRR15L	-0.020916
LHX8	-0.020911
LEPR	0.020901
PAPSS1	0.020897
SLC25A13	0.020894
IER3	0.020893
HAS2	0.020871
TIFA	-0.020830
TSPAN2	-0.020826
LGR6	0.020785
SCG5	0.020777
LGI2	0.020760
IGFBP6	-0.020748
MBOAT2	0.020700
ANKRD46	0.020695
TLCD1	0.020645
BMPER	0.020642
THY1	-0.020622
PGC	-0.020597
EPB41	0.020596
MAN1A1	-0.020592
PDK4	0.020562
LTBP1	0.020557
APP	-0.020538
IQGAP2	-0.020521
TUBG1	0.020478
SLC9A9	-0.020438
HIF1A	0.020432
PPFIBP1	0.020375
SCCPDH	0.020372
CD53	-0.020343
TSPAN8	-0.020231
AMPD1	-0.020196
SPRY2	0.020195
TLR8	-0.020192
STEAP1	0.020179
CCR5	-0.020174
TNFRSF9	0.020171
KCNT2	-0.020158
HMGCS1	0.020149
ANTXR1	-0.020148
FAM162A	0.020146
SOX6	-0.020119
TNFAIP8L3	0.020114
TNFRSF1B	-0.020112
CACHD1	-0.020104
PPM1K	0.020077
DHCR24	0.020069
SGCB	-0.020044
TIMP3	-0.020028
CHRDL1	-0.019999
SEMA4B	0.019948
C8orf4	-0.019942
WWC2	-0.019931
PDGFRA	0.019925
ALDH1A1	0.019922
PKIA	-0.019904
PODN	-0.019858
COL14A1	-0.019849
TNFSF10	-0.019822
GPR64	-0.019821
LPAR1	0.019818