!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!organism	Homo sapiens
!cell_type	MCF7cells
!pert_name	leucine
!pert_id	PubChemCID:6106
!organism	human
!pert_type	chemical
!end_metadata
INHBE	0.078129
CLGN	0.074864
SLC7A11	0.063568
SLC7A11	0.062586
ASNS	0.060166
DDIT3	0.057335
VEGFA	0.051304
MCM5	-0.051289
FEN1	-0.050878
MCM10	-0.050392
CHAC1	0.049646
FAM129A	0.048748
NUPR1	0.047444
TK1	-0.047246
SLC7A5	0.047210
ASCL1	-0.046128
FEN1	-0.045984
ASS1	0.045389
SPC25	-0.045365
LHX2	-0.044500
ASCL1	-0.043292
CCNE2	-0.043120
VEGFA	0.042693
MCM5	-0.042460
CCNE2	-0.042267
VEGFA	0.041291
MICB	-0.041029
CDC6	-0.040932
SLC3A2	0.040838
SCD	-0.040783
RAD51	-0.040604
PHGDH	0.040576
MCM4	-0.040401
SKP2	-0.040261
RPS6KA2	0.040150
MCM6	-0.039538
CDC45	-0.039509
DTL	-0.038858
ASF1B	-0.038846
GINS2	-0.038678
DDIT4	0.038607
WARS	0.038415
HSPA2	-0.038320
LRP8	-0.038304
SCD	-0.037871
ATF3	0.037638
MAP1B	0.037402
CDT1	-0.037286
DCLK1	0.037256
CDC6	-0.037125
CSRP2	-0.037094
ORC1	-0.036988
MCM4	-0.036866
MCM4	-0.036825
RNASEH2A	-0.036469
MCM3	-0.036069
MCM2	-0.036041
MARS	0.035849
LRP8	-0.035694
TXNIP	0.035323
SCD	-0.035021
WARS	0.034975
RFC3	-0.034885
TNFAIP3	0.034814
CEBPG	0.034471
HAUS5	-0.034304
MCM4	-0.034240
AGA	0.034073
GRB10	0.033976
FAM129A	0.033743
HIST1H4H	0.033728
LIG1	-0.033657
RFC3	-0.033579
CDK2	-0.033564
COMMD4	-0.033513
TIMP3	0.033412
BLM	-0.033387
INSIG1	-0.033375
DSN1	-0.033060
FANCI	-0.032925
INSIG1	-0.032810
LDLR	-0.032745
DHFR	-0.032710
GARS	0.032708
INSIG1	-0.032597
TYMS	-0.032571
RAD54L	-0.032466
DSCC1	-0.032258
CCL20	0.032049
CENPI	-0.031882
TUBG1	-0.031828
POLD1	-0.031777
FANCI	-0.031774
SKP2	-0.031759
DHFR	-0.031752
RFC2	-0.031725
PCNA	-0.031702
VEGFA	0.031684
LINC00341	0.031390
RIMS3	-0.031351
KCNS3	-0.031090
EIF4EBP1	0.030982
MCM7	-0.030955
LAMP3	0.030936
DHFR	-0.030855
CENPQ	-0.030846
BIRC3	0.030749
ICAM1	0.030733
SHMT2	0.030659
AGA	0.030482
MARS	0.030377
TSC22D3	0.030266
TRIB3	0.030208
GLRA3	0.030052
KIAA0101	-0.030022
RFC2	-0.029990
NES	-0.029892
TIMP3	0.029886
TXNIP	0.029869
HELLS	-0.029790
RIBC2	-0.029704
GDF15	0.029654
TXNIP	0.029569
CALR	-0.029539
N4BP3	0.029344
LDLR	-0.029339
C6orf48	0.029271
XPOT	0.029197
POLE2	-0.029141
MSH6	-0.029132
STC2	0.029125
ACD	-0.029103
GADD45A	0.029097
RFC5	-0.029073
COMMD4	-0.029017
CD55	0.028967
POLA2	-0.028897
RRM2	-0.028780
SFN	-0.028772
EBP	-0.028670
SCD	-0.028467
MSH2	-0.028342
MARS	0.028339
SLC1A4	0.028316
NFIL3	0.028303
RCN1	0.028301
CTNNAL1	-0.028294
FANCA	-0.028086
KCNE4	0.027950
SARS	0.027948
TMSB15A	-0.027934
BTG2	0.027852
PSMB3	-0.027748
PSPH	0.027674
DHRS3	0.027662
TNFAIP3	0.027613
KLHL24	0.027487
ALDOC	-0.027468
SLC7A1	0.027290
YARS	0.027224
MCM7	-0.027194
CENPU	-0.026956
PCK2	0.026882
S100P	0.026856
PRIM2	-0.026812
MSH6	-0.026792
KIAA0101	-0.026742
OVOL2	0.026721
IER5	0.026625
CDC25A	-0.026569
RND3	0.026550
CDK2	-0.026500
ABCA12	0.026489
SLC7A1	0.026469
SULF1	0.026348
CARS	0.026336
CHAF1A	-0.026319
POLA1	-0.026314
CAP2	0.026300
FADS1	-0.026260
IDI1	-0.026225
TGFA	0.026204
ATF4	0.026134
PCDH7	-0.026072
TIMP3	0.026047
E2F1	-0.025926
HAUS7	-0.025887
KCTD15	0.025777
SGCG	0.025730
MYCL	0.025700
AGA	0.025664
SLC7A11	0.025554
BRINP3	-0.025531
AOX1	-0.025520
JUN	0.025516
TSC22D3	0.025440
MYBL2	-0.025432
BDH1	-0.025426
RRM2	-0.025404
FANCG	-0.025381
HAT1	-0.025359
CAP2	0.025336
C1orf112	-0.025333
APOBEC3B	-0.025265
CORO1A	-0.025248
DLX2	0.025238
PIP5K1B	0.025232
CDKN2C	-0.025217
COCH	-0.025199
SFN	-0.025198
RFC5	-0.025186
NASP	-0.025108
SFN	-0.025104
MNS1	-0.025061
GLA	-0.025048
EFNA1	0.025029
RBM14	-0.025022
CD55	0.025000
WDHD1	-0.024985
SULF1	0.024983
GTPBP2	0.024978
NUP93	-0.024889
C9orf3	0.024844
CHRNA5	-0.024826
PHTF2	-0.024821
TUBB	-0.024803
RBCK1	0.024740
GMNN	-0.024648
SHMT2	0.024574
DHCR7	-0.024574
NCAPD3	-0.024567
FADS1	-0.024434
CARS	0.024417
CLIC3	-0.024366
RELB	0.024325
BPGM	-0.024314
DHCR7	-0.024256
CEBPB	0.024130
FADS1	-0.024124
TRIP13	-0.024117
ASCL1	-0.024085
MTHFD2	0.024084
FDPS	-0.024077
KLHL24	0.024048
STC2	0.024039
EBP	-0.024030
BRIP1	-0.024017
CASP8AP2	-0.023987
ATAD2	-0.023930
LDLR	-0.023925
RECQL4	-0.023905
CSPG5	-0.023849
PRIM2	-0.023849
CALR	-0.023841
DONSON	-0.023819
RNF187	0.023779
CHAF1A	-0.023769
GOT1	0.023747
BEST1	0.023727
BRCA1	-0.023688
NFATC2IP	-0.023665
SLC1A4	0.023649
HPGD	0.023592
FGF13	0.023583
SAMD4A	0.023515
GINS3	-0.023476
TUBB6	-0.023475
ESRP1	0.023473
IDI1	-0.023456
HPGD	0.023437
ICAM1	0.023419
HERPUD1	0.023329
CPM	-0.023288
API5	-0.023268
C8orf33	0.023245
EIF1	0.023231
NASP	-0.023206
CENPI	-0.023153
ERCC6L	-0.023119
KDELR3	-0.023115
STEAP1	0.023099
DCLK1	0.023057
EAF2	-0.023033
KLF5	0.023000
AARS	0.022946
GINS4	-0.022944
F7	0.022869
GINS1	-0.022831
HRK	0.022824
SALL2	-0.022797
CALR	-0.022789
CLK4	0.022754
DOCK10	-0.022748
ACAT2	-0.022744
AKR1C1	0.022703
EIF1	0.022674
LCN2	0.022645
EIF1	0.022642
RRM1	-0.022626
SHMT2	0.022576
TARS	0.022516
NR3C1	0.022514
SNRPA1	-0.022510
RPL37A	0.022497
PSME3	-0.022479
DET1	0.022472
PSMD12	-0.022443
CD44	0.022426
BTG1	0.022398
DHX9	-0.022371
CYP1A1	0.022370
SH3BGR	0.022368
ADPRM	0.022367
CLPB	-0.022351
S100A8	0.022344
SFPQ	0.022322
N4BP2L2	0.022298
DHRS1	-0.022284
SULF1	0.022277
HPRT1	-0.022239
IARS	0.022239
DUT	-0.022202
DHFR	-0.022198
TIPIN	-0.022197
NUP85	-0.022167
PHTF1	-0.022160
SGPP1	0.022157
CCNB1IP1	0.022153
BTG1	0.022070
SNRPA1	-0.022065
OGT	0.022035
CHAF1A	-0.021999
TIMELESS	-0.021996
SLC1A4	0.021948
SNRPA1	-0.021939
KDELR3	-0.021861
KDELR3	-0.021818
FAM69A	-0.021786
WDHD1	-0.021708
SAT1	0.021620
SNHG17	0.021583
FLRT3	0.021565
CFB	0.021553
CBS	0.021544
CSTA	-0.021541
FASN	-0.021531
FBXO11	-0.021523
FGFR4	-0.021514
HSPB11	-0.021477
NUP160	-0.021471
KMO	0.021433
RBL1	-0.021418
PKMYT1	-0.021405
NXN	-0.021377
NCAPG2	-0.021361
CAMTA1	-0.021312
DNA2	-0.021302
WDR76	-0.021263
DHX9	-0.021257
RFC4	-0.021252
E2F5	0.021251
RPA1	-0.021246
WIPF1	0.021245
DLEU1	0.021240
MGLL	0.021187
SAT1	0.021125
NUDC	-0.021112
CDK7	0.021105
PCBP2	0.021100
DPYSL4	-0.021077
NRGN	-0.020982
HN1L	-0.020957
PSMD3	-0.020953
SLC1A5	0.020948
RRM1	-0.020901
TAF1D	0.020896
CLIC4	0.020870
NFE2L1	0.020851
PPM1E	0.020841
RSL24D1	0.020811
ABHD3	-0.020795
DNAJB9	0.020762
NFE2L1	0.020753
HMGCS1	-0.020744
IL6ST	0.020740
PNP	-0.020728
DHRS2	0.020709
HPGD	0.020665
OAS1	0.020644
GINS3	-0.020628
NUDC	-0.020628
JUN	0.020616
PDK3	-0.020575
LMO4	0.020571
PAFAH1B3	-0.020542
RAD54B	-0.020536
CSE1L	-0.020533
ASMTL	-0.020521
F2RL1	-0.020473
ZNF322P1	0.020438
EHD1	-0.020419
SAT1	0.020411
LSS	-0.020402
MICA	-0.020399
TUBB3	-0.020363
CSE1L	-0.020363
UPF3B	0.020315
FIP1L1	0.020308
QPRT	-0.020284
TRMT1L	0.020274
RNF41	0.020262
LHFPL2	0.020245
POLE	-0.020223
MAP3K6	-0.020218
IRF3	-0.020196
HSPA14	-0.020186
CSE1L	-0.020153
TUBB3	-0.020152
AKR7A2	-0.020120
CCND3	-0.020094
TUBB4B	-0.020081
SLPI	0.020073
C4orf27	-0.020064
RAD54B	-0.020061
SNRNP25	-0.020057
EXO1	-0.020029
PKM	-0.020024
PSPH	0.020023
TIMM9	0.020002
VAMP4	0.019981
PAQR4	-0.019939
WIPF1	0.019928
SRSF7	0.019927
KRCC1	0.019920
C5orf28	0.019906
GNG4	-0.019893
C9orf91	0.019883
RPA1	-0.019881
MEX3C	0.019859
NFE2L1	0.019852
FN3KRP	-0.019838
UGT2B17	-0.019826
PODXL	-0.019815
MAP1LC3B	0.019799
BRCA1	-0.019785
CD44	0.019769
CARD10	-0.019752
YWHAH	-0.019719
S100A9	0.019712
NUP160	-0.019703
ABCA1	0.019655
IL6ST	0.019645
PRNP	0.019602
CCHCR1	-0.019596
PPP1R15A	0.019595
TAF1D	0.019582
CD44	0.019547
N4BP2L2	0.019544
GJA1	-0.019541
BDKRB2	0.019538
DCAF17	0.019496
PSMD1	-0.019480
C16orf59	-0.019431
TUBB4B	-0.019412
POLQ	-0.019390
NDRG1	-0.019335
FAM60A	0.019318
R3HDM2	0.019317
GLRA3	0.019299
MVK	-0.019277
SLC29A1	-0.019266
GAD1	-0.019261
POLQ	-0.019233
SHCBP1	-0.019208
RBM12	-0.019199
NAV2	0.019148
IFRD1	0.019143
ASMTL	-0.019136
RAD51AP1	-0.019130
EIF5	-0.019123
CHEK1	-0.019114
SGPL1	0.019106
KLHL7	-0.019088
CHEK1	-0.019083
C2orf49	0.019083
CD44	0.018998
EPAS1	0.018987
MB	0.018956
MSMO1	-0.018929
NFATC2IP	-0.018925
MYBL1	0.018918
MCMBP	-0.018913
PRPH	0.018905
MCAM	-0.018863
RET	-0.018851
PSMB9	0.018839
PASK	-0.018827
PQBP1	0.018825
DSCAM	0.018809
REEP1	-0.018807