!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	neocarzinostatin
!smiles	CC1C(C(C(C(O1)OC2C3CC#CC4C(O4)(C#CC3=CC2OC(=O)C5=C(C=CC6=C(C=C(C=C65)OC)C)O)C7COC(=O)O7)NC)O)O
!pubchem_cid	5282473
!cell_type	HEK293
!organism	human
!end_metadata
ATF3	0.247757
RPS5	0.184015
TNFAIP3	0.178898
NFKBIA	0.170206
RPL19	0.155266
IER2	0.155186
IER3	0.148803
DUSP1	0.142792
CFL1	0.138186
RPS27A	-0.137613
RPS10	0.132192
JUND	0.130628
RPL7	-0.125434
VIM	0.123634
HLA-C	0.103449
RPL41	0.100453
RPL36	0.099683
ATF4	0.094878
UBE2C	-0.094833
EIF1	0.090975
RPL34	-0.088038
MIF	-0.087730
NGFRAP1	-0.087583
HNRNPA1	0.086814
UBE2S	-0.078733
HSPA8	-0.075703
XIST	-0.073788
RPRM	-0.072667
RPS7	0.072563
PTTG1	-0.071141
RPS18	-0.071140
RPS27	-0.069298
HLA-B	0.069240
DDX5	0.068912
ZNF207	0.067977
GSTP1	-0.067633
YWHAE	0.067392
HSP90B1	-0.066237
NONO	0.065779
CD83	0.064449
RPL13A	-0.063665
DHCR24	-0.063603
COX7A2	-0.063387
HMGB1	0.062222
GADD45A	0.060301
GADD45B	0.060089
RPL35	-0.059574
RBM39	0.057196
UQCRFS1	0.057014
RPL11	-0.056305
SLIT2	-0.055966
PPIA	-0.055846
ID2	-0.055726
RPL21	-0.055324
NUP153	0.055272
CCL20	0.054376
RPL32	0.054140
SOX3	-0.052121
RPS29	0.052011
SEC61B	-0.051570
CXCL8	0.051130
H3F3B	0.051024
TYMS	0.050512
LDHA	-0.049747
PSMC5	0.049619
MYBL2	0.049580
DBI	-0.049046
CDKN1A	0.048584
RPS24	0.048342
HMGN2	0.047894
ATP5J2	-0.047680
ERH	0.047495
UBA1	-0.047231
PRC1	-0.047063
AURKA	-0.047030
TPR	0.046624
TMEM258	-0.046581
HEY1	-0.046056
MCM3	0.046024
GNG5	-0.045679
TUBB	-0.045609
PBX2	-0.044955
RPL23	0.044934
PABPC3	0.044932
PFDN5	0.044418
BASP1	-0.044325
U2AF1	0.044306
GNG10	0.044033
CCT4	0.043435
RRM2	-0.043371
EIF2S2	0.043167
RHOB	0.042951
RPS16	0.042479
PPP1R15A	0.041979
XRCC6	-0.041725
ACTB	-0.041471
KPNA2	-0.041465
RPS15A	0.041010
HNRNPAB	0.040932
ELOVL5	0.040858
GPX4	0.040705
YWHAZ	-0.040310
SLC25A3	0.040102
RPL7A	-0.039921
PKM	-0.039710
NOP56	0.039705
IDI1	0.039644
GLO1	0.039611
ANXA2	0.039607
ENO1	0.039342
DSP	-0.038603
PITPNB	0.038368
HSP90AA1	-0.038163
SRSF6	0.038104
SLC25A5	-0.038055
EGR1	0.038035
CYCS	0.038018
COX4I1	0.038010
FEN1	0.037568
MCL1	0.037521
ACLY	-0.037293
ZFAND5	0.037075
RPS8	0.036743
ATP6V1F	-0.036609
DYNLL1	-0.036293
NDUFA3	-0.035874
PSMB1	0.035775
RPL36A	0.035246
SDC4	0.035216
RAB9A	0.035149
CALM3	-0.035104
SRSF2	0.034918
RELB	0.034880
CKS2	-0.034495
LMO4	-0.034380
EIF4A2	0.034317
RPL18	-0.034167
MAPRE1	0.034005
UBB	0.033966
RRM1	0.033816
RPS3	-0.033781
TP53	0.033730
CDC20	-0.033600
PGK1	0.033412
TPT1	-0.033296
MCAM	0.033233
LSM4	-0.033063
PFN1	-0.032999
BTG3	0.032950
RPL39	0.032750
SRP9	-0.032492
MORF4L1	0.032207
RPS28	0.032151
RPL13	-0.032141
CD63	-0.031671
TAGLN2	-0.031534
RPS15	0.031443
PEBP1	-0.031343
PSMA2	-0.031125
EIF4H	-0.031014
RPL8	0.030951
COX8A	-0.030759
ARPC5L	0.030625
SNRPB2	-0.030391
GLTSCR2	0.030219
H2AFZ	0.030154
TARS	0.030097
CDC25B	-0.030091
FADS2	-0.029883
SNRPG	-0.029849
TOP2A	-0.029706
MCM5	0.029695
TAPBP	0.029669
HEBP2	-0.029624
IFNGR2	0.029562
SET	0.029520
SAT1	0.029445
HLA-A	0.029333
ATP5G2	-0.028887
GAPDH	-0.028860
AGPAT1	-0.028800
RPL28	0.028780
PLK1	-0.028778
ENSA	0.028420
USP1	0.028414
STARD7	0.028393
FAM53C	0.028292
TMSB10	-0.028218
SLC38A2	0.028164
PSMC1	0.027882
VAT1	-0.027744
MCM2	0.027579
GABARAP	-0.027404
RHOA	-0.027330
PAPD7	0.027300
CST3	-0.027256
RFC3	0.027172
HMGCS1	0.027170
SDCBP	0.027129
RPL27A	-0.026952
ARL6IP5	-0.026940
CDK16	-0.026879
CUTA	0.026795
BTF3	0.026758
MT2A	-0.026751
SQLE	-0.026665
TUBB4B	0.026611
PABPC1	0.026558
RPS21	-0.026503
XPO1	-0.026208
TNFRSF9	0.026095
NME1	-0.026087
SF3A1	0.026016
BCAP31	-0.025867
SRSF9	0.025718
YBX1	0.025576
EIF2AK1	0.025234
TTK	-0.025086
ZWINT	-0.025020
JTB	-0.024988
TSEN34	-0.024978
MGST3	-0.024832
IARS	-0.024757
USP14	0.024743
ZNF580	0.024563
RPL27	-0.024420
MARCKSL1	0.024357
TIMM8B	-0.024273
CTPS1	0.024258
CDK1	-0.024177
HSPA9	0.024054
MSX1	0.023998
TMBIM6	0.023913
CD81	0.023755
DDX21	0.023733
MARCKS	-0.023726
CXADR	-0.023719
EEF1A1	-0.023613
SRRM1	0.023544
CCNC	0.023537
KIF20A	-0.023508
TNFRSF12A	0.023451
POLR2G	-0.023429
DUSP8	0.023386
UBE2D3	0.023370
CAPRIN1	-0.023324
PPP2R2A	0.023268
TRIM28	0.023211
KLF10	0.023195
CDKN2C	-0.023122
CSNK2B	0.022978
ANP32A	-0.022973
FAU	-0.022931
FDFT1	-0.022828
LBR	0.022821
COX7B	-0.022815
PIN4	-0.022791
IRS2	-0.022635
VDAC3	-0.022626
EIF1AX	0.022580
EID1	0.022394
SEPT9	-0.022356
YY1	0.022298
DDX24	0.022286
CSTB	-0.022178
ELAVL1	-0.022174
AP3S1	-0.022078
BRD2	0.022035
POLE3	0.021878
NDUFB3	-0.021708
SERP1	-0.021686
RPS27L	-0.021666
PRDX1	-0.021663
UQCR11	-0.021657
LAGE3	-0.021561
EIF5	0.021518
PPP2R1A	0.021483
SFPQ	-0.021445
CANX	-0.021374
NDUFAB1	-0.021368
TMEM59	-0.021292
ACTN1	-0.021275
CCNL1	0.021244
GALNT2	-0.021225
MYL12B	0.021139
DYRK1A	0.021077
CSRP2	0.021032
CCNB2	-0.021007
MAZ	-0.020962
HOXA5	-0.020944
PSMD14	0.020850
GTF2H5	-0.020825
RBBP8	0.020817
ATP6AP2	-0.020779
ATP1B3	0.020769
LAMP1	0.020756
IRAK1	0.020733
ZMPSTE24	-0.020691
RPL6	0.020616
TFAP2A	-0.020449
TUBB3	0.020435
RANBP1	0.020424
RAE1	0.020410
PSMD11	0.020388
GMPS	0.020378
PPP1R11	-0.020255
HNRNPA0	-0.020097
NIPSNAP1	-0.020083
C14orf2	-0.020039
ARL2	-0.020039
FUS	0.020034
ATP1A1	-0.020011
CNBP	0.019984
ACP1	0.019947
NEFL	-0.019931
DIABLO	0.019832
C11orf58	-0.019821
ECI2	-0.019762
DNPH1	-0.019736
P4HB	-0.019727
ID4	-0.019611
CDC5L	0.019606
LSM2	-0.019592
RPL15	0.019567
MDH2	-0.019503
NDUFB4	-0.019498
BAG6	0.019474
UQCR10	-0.019442
CARS	0.019441
HMMR	-0.019372
COPB1	-0.019334
NGRN	0.019252
SRP19	0.019211
ATP6V1G1	0.019210
FAM60A	0.019207
RPL5	-0.019142
CSE1L	-0.019068
PPP2CA	0.019064
PEA15	0.019056
CTBP2	-0.019053
CCT8	0.019007
EIF1B	0.018917
TPX2	-0.018894
PSMD12	0.018881
CALM2	0.018773
RPS14	-0.018753
SKAP2	-0.018716
CCNI	-0.018711
SLC20A1	0.018687
RSRC2	0.018649
MAPK6	0.018634
ATP1B1	-0.018538
USP9X	0.018523
CNN3	0.018518
PSMC2	0.018423
LAPTM4B	-0.018361
LMNB1	-0.018347
PSMA1	0.018265
ABCD3	-0.018261
VPS26A	-0.018233
CENPA	-0.018182
DDOST	0.018093
RNASEH2A	-0.018058
ARPC5	-0.017906
FAM50A	-0.017820
RAB1A	-0.017798
MAGED1	0.017757
WRB	-0.017719
MEA1	0.017719
SUB1	0.017658
HLA-G	0.017598
SNHG17	0.017548
NXF1	0.017544
POLR2E	-0.017481
ABLIM1	-0.017475
RFC4	-0.017430
IMPDH2	0.017423
SLC6A8	0.017369
MTHFD2	0.017358
DSTN	-0.017344
ID3	-0.017300
KLC2	-0.017282
RPL24	-0.017277
EIF2S3	0.017192
KPNB1	-0.017179
UBE2I	-0.017145
ATP5G3	-0.017145
RPL23A	0.017127
PGRMC1	-0.017096
VCAN	-0.017049
GOLPH3	0.017031
NAE1	0.017004
ZNF146	0.016982
SRP14	0.016974
RPS4X	0.016952
GARS	0.016904
FAM8A1	-0.016899
SNRPD3	-0.016891
RNF103	0.016888
NHP2L1	-0.016883
CYR61	0.016882
RING1	-0.016879
HSPH1	-0.016806
SRSF5	0.016781
ACAT1	-0.016737
FOXC1	-0.016733
NCKAP1	0.016728
HSD17B10	-0.016686
CCNA2	-0.016656
NDUFB1	-0.016654
RPL22	-0.016422
BARD1	0.016407
GTF2B	0.016397
UQCRH	-0.016382
BTBD2	-0.016337
RAD23A	-0.016313
HOXA10	-0.016270
PSMD2	0.016244
RAN	0.016233
GMNN	0.016189
SSR4	-0.016184
C20orf24	0.016103
ATP5B	0.016093
RPS11	0.016089
EWSR1	0.016077
BRD4	0.016008
PHB2	0.015977
RANGAP1	-0.015956
SEPT2	-0.015923
BMP2	0.015886
CDC42SE1	0.015883
TBCA	0.015868
HNRNPDL	0.015845
LDOC1	-0.015818
H1FX	-0.015809
CYC1	0.015803
TNFAIP1	0.015801
SLC25A11	-0.015789
EEF2	-0.015768
HNRNPF	-0.015753
ITM2C	-0.015735
PUM1	0.015731
GOT2	0.015729
SMARCE1	0.015719
SRI	-0.015637
TOMM20	0.015628
ACACA	-0.015610
RELA	0.015600
EIF4G2	0.015591
RPS12	-0.015576
NFKB1	0.015529
RPS26	-0.015479
EIF3E	0.015452
TRMT11	0.015383
BTG2	0.015307
WBP5	0.015185
CDK2	-0.015150
NKRF	0.015138
TLE1	-0.015126
CTDNEP1	0.015095
SRPR	0.015063
ORC6	0.015033
GNL2	0.015019
BCAS2	0.015005
PPM1A	0.014908
DDB1	-0.014906
NCAM1	-0.014864
PPP1CC	0.014858
MACF1	-0.014816
ATP6V0E2	-0.014788
NFIB	-0.014782
B2M	0.014772
SDF2L1	-0.014751
EIF2S1	0.014667
EIF4ENIF1	0.014646
PTCH1	-0.014639
HDGF	-0.014626
NDUFA9	0.014624
TARDBP	-0.014620
KMT2A	0.014618
POLD1	-0.014603
SESN1	-0.014582
EFNB2	0.014564
SNRNP70	0.014563
RPP30	0.014528
BCL11A	-0.014516
SCD	-0.014506
HSPD1	0.014480
DPYSL2	-0.014451
HYOU1	-0.014447
BUB1B	-0.014445
EIF3F	0.014418
PPIB	0.014404
BHLHE40	0.014336
VPS41	-0.014331
POLR2F	-0.014319
CHAF1B	0.014297
ETF1	0.014273
HIST1H4C	-0.014270
PICALM	-0.014256