!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	PLX4720
!smiles	CCCS(=O)(=O)NC1=C(C(=C(C=C1)F)C(=O)C2=CNC3=NC=C(C=C23)Cl)F
!pubchem_cid	24180719
!cell_type	HT29 and Colo205 parental colorectal cancer (CRC) cell lines
!organism	human
!end_metadata
SPRR1B	0.153070
SPRR1A	0.101214
PROM1	-0.093341
GZMA	-0.089658
CDH17	0.088745
UGT2B4	-0.082941
DHRS9	0.078970
CEACAM6	0.077089
BCAT1	0.069335
S100A2	0.065904
SPRR3	0.061817
FZD10	-0.061479
SPINK1	-0.060741
AGPAT9	0.059214
GEM	0.057485
KRAS	0.055126
AKAP12	0.053585
EPHX4	0.053136
LYRM5	0.052927
SNX10	0.052601
LAMC2	0.051301
PDZK1	-0.051166
DDIT4	-0.050433
FKBP11	-0.050002
POU2AF1	-0.049616
AHNAK2	0.049473
DPYSL2	-0.048759
PRSS1	-0.048497
SDCBP2	0.048010
NFE2	-0.047808
ECI2	0.047338
GPA33	0.047244
SLC23A1	-0.046645
INSIG1	-0.045813
PRPS2	-0.045300
REG4	0.045220
GLUL	-0.044378
ELOVL7	-0.044007
ACSM3	-0.043485
ETNK1	0.043417
COL9A3	-0.043349
SLC22A4	0.043107
C15orf48	-0.043096
IGFL2	0.042727
PCSK9	-0.042468
LINC01207	0.042010
SBSPON	-0.042009
DPEP1	0.041600
MALL	0.041364
LOXL1-AS1	-0.041028
CCL20	-0.040009
CA9	-0.039798
NR2F1	-0.039673
LOXL1	-0.038958
SERPINE2	0.038787
PMEPA1	0.038311
GNAI1	-0.038147
NNMT	-0.037815
CEACAM5	0.037749
CAPN8	0.037639
CXCR4	-0.037629
ARL14	0.037608
FRY	-0.037170
CD99	0.036866
TMPRSS3	-0.036566
LINC00992	-0.035559
UGT2A3	-0.035388
TNC	0.035326
CD55	0.035228
CDKN1B	-0.035152
HOTAIR	-0.034997
C6orf141	0.034885
TCN1	0.034784
MMP1	0.034781
PLA2G4A	-0.034541
MATN2	-0.034492
TLR3	-0.034472
DNAJC12	-0.034356
NHS	-0.034334
SATB2	0.034049
GPX3	0.033815
IL6R	0.033677
CTTNBP2	-0.033628
ACSL1	-0.033416
ITGA2	0.033055
ID2	-0.032952
SLC35G2	0.032779
PLSCR4	-0.032740
NOXO1	-0.031985
CASC1	0.031984
CES1	-0.031722
MUC17	0.031399
IFI27	0.031364
MUCL1	-0.031358
PHGDH	-0.031355
CCDC109B	0.031337
ICAM4	-0.031318
SSUH2	0.031205
TESC	-0.031119
ALDH8A1	0.031076
KIAA1614-AS1	0.030938
CKB	-0.030624
MLLT11	0.030430
CLIC3	-0.030424
LRRC31	-0.030355
LINC01106	-0.030331
ASL	0.030141
ANXA9	-0.030048
GABRP	-0.029854
HEPH	0.029851
UPP1	0.029469
RNASE4	-0.029384
SLC38A11	-0.029342
CALB1	0.029221
ND6	0.029210
HSPA1A	-0.029192
ROR1	-0.029156
MBOAT2	0.028963
C17orf99	-0.028943
GRB10	0.028902
NTSR1	0.028857
S100A3	0.028804
IGFBP6	0.028703
HLA-DMA	-0.028602
BTBD16	-0.028600
AQP1	0.028485
LCN2	-0.028434
MAOB	0.028425
PPP1R14C	0.028308
CAV1	0.028265
CMAS	0.028256
KRT40	0.028214
PLA1A	-0.028181
SLC22A3	0.028170
PHACTR3	0.028088
SCEL	0.028046
KCTD14	-0.028038
LOC101929549	0.028037
MAGEA6	-0.027998
KIT	-0.027973
ITGA1	-0.027934
CST7	-0.027931
MAGEA3	-0.027904
GALNT5	0.027796
ANG	-0.027742
FAM69A	0.027689
LOC285812	-0.027609
SST	0.027584
PKIG	-0.027536
ANTXR2	0.027482
FAM219A	0.027392
CYP4X1	-0.027378
MYH15	0.027278
RHOU	0.027265
LINC00973	0.027245
CPNE2	-0.027240
HOXB9	-0.027143
CAPN12	-0.026905
SLC41A2	0.026898
LINC00460	0.026823
CD109	0.026816
ARL4C	0.026742
PMM1	-0.026687
CHST4	-0.026632
LAMB3	0.026631
SLC22A15	-0.026580
EFNB2	0.026559
TSPAN12	-0.026515
PRSS23	0.026478
FGF9	-0.026468
BTBD11	0.026442
WBP5	-0.026419
IL22RA1	0.026394
KIFAP3	0.026384
SQLE	-0.026374
CPLX1	0.026323
BTN3A3	-0.026322
TNFRSF11A	-0.026294
LGALS1	-0.026191
GPR87	0.026167
VAC14-AS1	0.026140
SEPW1	0.026102
GBP1	-0.025990
SERPIND1	0.025920
EPHB6	0.025816
NPY1R	0.025775
TMC7	0.025712
LOC286191	-0.025646
AQP5	-0.025601
ZNF185	0.025591
S100A11	0.025469
ERP29	-0.025443
TBC1D4	-0.025433
ZBED3	-0.025417
LRRC2	-0.025343
PDLIM1	0.025322
SLC43A1	-0.025307
LINC00263	-0.025297
LETMD1	-0.025277
INSC	0.025267
HEXIM2	-0.025265
TOB1-AS1	-0.025219
CYP51A1	-0.025200
PRKXP1	-0.025198
CFH	-0.025112
ABLIM3	0.025083
SCD	-0.025080
COL17A1	0.025061
TXK	-0.024992
SMOC2	-0.024904
ARNT2	-0.024827
XK	0.024734
MTERF2	-0.024704
LMO4	-0.024668
ALDH6A1	-0.024607
SLC5A1	-0.024604
TCHH	0.024555
TYMSOS	-0.024435
MIR22HG	0.024400
TPPP3	0.024383
PXN-AS1	-0.024356
RAB26	-0.024352
FOSL1	0.024316
SLPI	-0.024283
MSMO1	-0.024271
IGSF9	-0.024257
HAS3	0.024218
EMP1	0.024188
TMEM45B	0.024178
POLD4	0.024031
LINC00525	0.023932
TUBA1A	0.023856
ANXA1	0.023848
F3	0.023804
GAS2	-0.023781
LOC101929719	0.023682
GOLT1A	0.023671
PSTPIP2	-0.023661
NTHL1	-0.023625
TNNT1	-0.023538
AHRR	0.023522
LINC01169	-0.023443
EPHB2	0.023433
LOC102724094	0.023380
TMEM263	-0.023373
CYP3A5	0.023294
MT1F	-0.023282
ZNF320	-0.023121
ETS1	0.023095
OSBPL3	0.023064
ADAM1A	-0.023006
TCEAL3	0.022938
PSAT1	-0.022883
FAM189A1	-0.022853
FAM149A	-0.022817
MGAT4A	0.022797
LOC344887	0.022797
ADAMTS15	0.022735
ST6GALNAC1	-0.022716
LPCAT2	-0.022695
SCG5	0.022675
ACPP	-0.022651
KITLG	-0.022641
HMGN3	-0.022618
LYN	0.022612
MAP3K8	-0.022571
FEM1C	0.022519
SEMA3C	0.022515
SLC35D3	0.022486
GPR115	0.022477
NFIB	-0.022282
CTH	-0.022236
PRSS3	0.022222
JADE1	-0.022193
TP53	-0.022133
DHCR7	-0.022094
C9orf152	-0.022031
EIF4EBP1	-0.022001
TMPRSS4	0.021938
SI	0.021931
ZNF850	-0.021908
SH3BGRL3	0.021885
KIAA0040	0.021868
PHEX	0.021831
PROCR	0.021724
SRI	-0.021698
REN	0.021690
LOC100506325	0.021687
TMEM158	0.021670
NOD2	-0.021669
CRACR2B	-0.021629
SCG2	0.021566
LINC00341	-0.021563
FLJ32255	0.021549
GBP3	0.021488
C12orf57	-0.021486
CDX2	0.021434
PDCD4	-0.021414
GALM	-0.021413
NEO1	-0.021384
PRKACB	0.021351
PARM1	0.021332
GDA	-0.021325
CEL	-0.021284
COLCA2	-0.021277
FREM2	-0.021249
GRB14	-0.021225
LINC00261	-0.021215
ZFPM2	-0.021213
ZNF22	-0.021183
CTSL	0.021161
DHRS2	-0.021141
FXYD5	0.021094
IFI16	-0.021026
VSNL1	0.021004
BNIP3L	-0.020987
C5orf17	0.020986
EEA1	-0.020957
SLC25A45	0.020941
DIAPH2-AS1	0.020934
DSC2	0.020933
APOBEC1	0.020927
MUC3B	0.020898
PNPLA3	-0.020897
HTATSF1P2	0.020896
PFKM	-0.020896
AGBL2	-0.020894
LGALS2	-0.020883
ZNF300	-0.020882
AGR3	0.020855
RNF183	-0.020842
SHMT2	-0.020808
CYB5R2	-0.020774
SGPP1	-0.020741
KIAA1586	-0.020714
AKR1C2	0.020651
RBPMS2	0.020629
PBX1	-0.020594
CPB2	-0.020568
TJP3	-0.020562
LOC286161	-0.020521
DCLK1	0.020515
IL20RB	-0.020500
CNN3	-0.020488
CAPRIN2	0.020475
AKR1C1	0.020460
CCR1	0.020458
DYX1C1	-0.020451
CHEK2	-0.020430
BATF	0.020427
IRAK1BP1	-0.020420
EZR	0.020395
KIAA0226L	-0.020393
PSD3	0.020370
CREB3L4	-0.020368
PTGER4	-0.020328
SLC2A1	0.020258
DET1	-0.020252
MANBA	-0.020248
CTSS	0.020236
DFFB	-0.020221
FGD4	0.020167
FRMD6	-0.020163
KIZ	-0.020152
IFIT1	0.020138
SYNC	-0.020132
SLC44A2	-0.020122
HOXA1	0.020094
ARRDC3	0.020067
MYH4	0.020039
CNKSR3	-0.019988
MMP7	0.019951
H19	-0.019886
ECM1	0.019835
ACAT2	-0.019832
EFHD2	0.019798
COX1	0.019795
SLC19A2	-0.019773
GJB3	0.019768
CAPN2	0.019755
OASL	0.019746
NDRG1	0.019689
KBTBD6	-0.019673
PCK2	-0.019661
PDGFA	0.019641
NR2C1	-0.019640
FDFT1	-0.019622
GMFG	0.019584
STK17A	0.019578
NIPSNAP1	-0.019568
TMED6	-0.019552
LEPREL1	0.019551
PLEKHA7	-0.019522
FAM3D	-0.019497
CXADR	-0.019457
TRIB3	-0.019454
PAPSS2	-0.019328
ENDOD1	0.019324
C7orf55	-0.019309
PITX2	-0.019300
RTP4	-0.019294
PLAU	0.019294
TSFM	-0.019284
MAP3K4	-0.019278
MAP2K6	-0.019270
H2BFS	0.019265
ERCC1	0.019250
SNX9	0.019248
SLC36A4	0.019201
CAV2	0.019186
HIST1H2BC	0.019155
CDCA7	-0.019127
COBL	0.019125
CCDC77	-0.019125
MALRD1	0.019070
TMEM154	0.019063
ST5	-0.019060
NRIP3	0.019046
HCN1	0.019030
GULP1	0.019015
DNAJB9	-0.018999
ELOVL1	0.018989
GRAMD1B	0.018985
LOC283357	-0.018983
SERTAD1	0.018981
CDH13	-0.018978
PIAS3	-0.018962
PRR15L	-0.018951
PMCH	-0.018939
CREB5	0.018902
MYCL	-0.018841
ABCB1	-0.018806
ADRA2A	-0.018783
KHDRBS3	-0.018777
DPM3	-0.018774
FDXR	-0.018747
EIF4B	-0.018700
FXYD2	0.018662
C6orf223	-0.018651
PLD1	-0.018638
CADPS2	-0.018638
SFR1	0.018637
TLR5	0.018634
ZNF766	-0.018631
ST6GAL1	-0.018618
FAM60A	-0.018603
UMODL1	-0.018602
DENND5B	-0.018600
MYOF	0.018591
CEP83	-0.018546
LAMP3	-0.018545
CD97	0.018541
FOXC1	0.018520
LTA4H	-0.018483
RARRES3	-0.018455
KDM5D	0.018452
MTMR11	0.018421
FBXO46	-0.018406
MT1HL1	-0.018380
SLC28A3	-0.018379
MYB	-0.018334
TMEM187	-0.018319
SLC14A1	-0.018288
COLGALT2	-0.018285
PLCD3	0.018270
SDPR	-0.018267
ATP2B4	0.018217
HILPDA	-0.018194
DSG2	0.018189
CKAP4	-0.018184
CORO2A	0.018172
IFI6	-0.018154
PIR	0.018128
ALDH3A1	0.018126
LHFPL2	0.018113
FOXL1	0.018112
PLEK2	0.018106
LAMB1	-0.018090
KLHL24	-0.018084
DCBLD2	0.018081
SULT2B1	0.018073
SERPINB5	0.018066
KIAA1462	0.018037
SGK3	0.018031
LTBP1	0.018019
RPL31	-0.018001
PCGF5	0.017996
FLJ22763	-0.017991
FAM129A	-0.017988
EGFR	0.017978
LOC400684	-0.017943
ALMS1-IT1	-0.017907
ROPN1B	-0.017895
STRIP2	0.017888
LAMTOR4	-0.017883
POC1B	-0.017875
TFAP2A-AS1	-0.017875
SNHG8	-0.017872
ISG20	0.017864
APOBEC3G	-0.017842