!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!drug_name	EPZ004777
!smiles	CC(C)N(CCCNC(=O)NC1=CC=C(C=C1)C(C)(C)C)CC2C(C(C(O2)N3C=CC4=C3N=CN=C4N)O)O
!pubchem_cid	56962336
!cell_type	MV4 -11 leukemia cell line - Day 6
!organism	human
!end_metadata
CFD	0.229631
LYZ	0.197933
CTSG	0.196705
ELANE	0.125179
LDHA	-0.125058
HLA-DRB1	0.122445
SNRPG	-0.114650
TYROBP	0.114171
HLA-DRA	0.113256
AZU1	0.099507
RAN	-0.098412
SNHG5	0.092374
PRTN3	0.091830
FABP5	-0.088368
BEX1	0.088175
MAN2B1	0.085367
RPL36	0.084143
LGALS1	-0.083932
H2AFZ	-0.081195
YBX1	-0.080114
RPS4Y1	0.079040
LMNB1	-0.076062
HSP90AA1	-0.073308
ACTB	-0.072612
PTMA	-0.070972
SERPINF1	0.069474
SLIRP	-0.069412
PGAM1	-0.067390
PCNA	-0.066493
EMB	-0.066349
ZFAS1	0.064972
SLC25A6	0.063477
RPS4X	0.063084
RPL36A	0.063041
RPS8	0.062862
OAZ1	-0.061365
PTGES3	-0.060290
FTH1P5	0.059115
RPL24	0.058823
HSPE1	-0.058692
NME1	-0.058606
HLA-A	0.058468
NCOA4	0.058371
GLTSCR2	0.058014
CBWD1	-0.057866
RRM2	-0.057291
RPS27L	-0.057058
HLA-DPA1	0.057043
HLA-B	0.056332
LAPTM5	0.056316
PSME2	-0.056054
DDX39A	-0.055978
TUBB	-0.055190
RPL12	0.055020
PFN1	-0.054879
C1QBP	-0.054781
ATP5J	-0.054484
MFSD1	0.053935
MIF	-0.053884
RPL26	0.053735
IGF1	0.053639
RPS25	0.053284
GOLGA8H	-0.053003
TIMP1	0.052401
EEF1G	0.052188
EIF3E	0.052168
CST3	0.051656
FTH1	0.051134
RPL29	0.050878
EEF1B2	0.050069
CES1	0.049895
MSN	-0.049731
SNHG6	0.049392
USMG5	-0.048134
RPL36AL	-0.048080
PSAP	0.047717
FTL	0.047196
ITM2C	0.046967
UBE2S	-0.046873
ATP5G3	-0.046805
GPR160	0.046727
NOP10	-0.046513
PFDN5	0.046372
UBE2C	-0.046367
TARP	-0.046195
TXNIP	0.045984
HMGB1	-0.045951
HSPA8	-0.045883
UQCRFS1	-0.045872
HAT1	-0.045835
CLIC1	-0.045824
QARS	0.045795
INSIG1	-0.044979
GRN	0.044896
GARS	-0.044558
ZWINT	-0.044551
CHSY1	-0.044509
UBL5	-0.044296
SNRPD2	-0.044269
SNHG8	0.044239
ERP29	0.044197
RPL34	0.044185
CD74	0.044051
COX6C	-0.043563
HSPB1	-0.043170
SNRPD3	-0.043139
TUBA1C	-0.043085
C12orf57	0.042972
MCM2	-0.042851
HLA-C	0.042827
EEF2	0.042419
RPSA	0.042295
RPL19	0.042247
EIF3H	0.042230
TUBA1B	-0.042214
RPS20	0.041913
TFRC	-0.041649
TPT1	0.041614
RPL27	0.041451
NAP1L1	0.041420
CDC123	-0.041365
RPL4	0.041327
CFL1	-0.041161
ACADVL	0.041127
UGCG	-0.040990
GAPDH	-0.040872
MS4A3	0.040660
RPS13	0.040162
RPL30	0.040053
HLA-DPB1	0.039975
CHCHD2	-0.039967
RPS10	0.039943
PABPC3	0.039822
DEK	-0.039698
ATF4	-0.039499
GNB2L1	0.039300
RPL39	0.039091
RPL7A	0.038773
DDX21	-0.038725
LMO2	-0.038697
SAMHD1	0.038674
RPL13	0.038608
ERH	-0.038373
RPS27	0.038324
RPL22	0.038271
RPL32	0.038247
C6orf48	0.038216
MYO1G	0.038048
IDI1	-0.037874
PDLIM1	0.037872
PGK1	-0.037598
ENO1	-0.037531
PSAT1	-0.037467
RPL31	0.037399
RPL11	0.037290
RPL21	0.037282
RPL35	0.037275
GABARAP	0.037257
NPM1	-0.037198
CCT2	-0.037022
CLEC11A	0.036931
RPL3	0.036925
ALDOA	-0.036891
BASP1	0.036549
EEF1D	0.036166
HCST	0.036016
TMEM14C	0.035928
PYGL	-0.035806
UHRF1	-0.035597
ADA	0.035453
RPS29	0.035184
NDUFB9	-0.034974
RHOA	-0.034953
EIF4H	-0.034940
FLT3	-0.034843
SRSF2	-0.034757
VIM	0.034665
HSP90AB1	-0.034632
MCM7	-0.034547
FDFT1	-0.034220
SLBP	-0.033925
IARS	-0.033902
NDUFV2	-0.033849
SNRPD1	-0.033748
PSMA4	-0.033746
EIF4EBP1	-0.033360
EPB41L4A-AS1	0.033254
FAM46A	0.033181
HSPD1	-0.033095
VDAC1	-0.032849
GBE1	-0.032803
CSTA	0.032801
RPL14	0.032764
SOD1	-0.032663
COMMD6	0.032631
LAPTM4A	0.032401
UFC1	0.032302
EIF3K	0.032300
TCEB1	-0.032272
CDCA7L	-0.032161
CCT8	-0.032128
EIF3G	0.032053
PLAC8	0.032015
ARHGDIB	-0.031847
KPNA2	-0.031820
TYMS	-0.031792
RPL15	0.031776
SRSF9	-0.031772
MRPL33	-0.031710
CHI3L1	0.031579
RPL22L1	0.031458
PRC1	-0.031446
CEBPA	0.031428
RPL10A	0.031369
NDUFB5	0.031062
RPA3	-0.030908
NCL	-0.030861
ALYREF	-0.030810
LDHB	-0.030745
SLC25A3	-0.030504
DBI	-0.030487
HMGN2	-0.030385
IRX3	0.030310
BUB1B	-0.030233
SLC38A2	-0.029990
RPL9	0.029988
DUT	-0.029807
SSR4	0.029771
TAGLN2	-0.029691
LCP1	-0.029688
HNRNPA2B1	-0.029598
SNRNP25	-0.029382
HLA-DMA	0.029339
SLC7A5	-0.029321
TUBB6	-0.029288
APOC2	0.029259
H3F3B	-0.029166
SNRPB	-0.029161
EIF3D	0.029009
RPL17	0.028973
RNASEH2A	-0.028944
TUBB4B	-0.028469
B2M	0.028390
SEC61G	-0.028361
PAICS	-0.028352
RPS7	0.028266
F13A1	0.028189
CKS2	-0.028107
RPL5	0.028087
PTPN6	-0.028042
GPI	-0.027861
RPL6	0.027643
EIF4A1	-0.027533
UQCRH	-0.027530
HNRNPF	-0.027443
PSMB3	-0.027356
TRPM4	0.027328
MRPL51	-0.027254
PSMA6	-0.027169
ATP5G2	0.026849
RPL23	0.026801
MRPL3	-0.026759
DHX15	-0.026721
PLP2	-0.026646
RPLP0	0.026474
MSMO1	-0.026338
MYO1F	0.026295
CD302	0.026265
CKS1B	-0.026185
UQCRC1	-0.026180
CD37	0.026114
RPLP1	0.026074
FEN1	-0.025904
PPT1	0.025813
TIMM10	-0.025787
CENPW	-0.025748
HMMR	-0.025664
PSMC3	-0.025541
PPIA	-0.025518
SMC4	-0.025466
EIF3L	0.025410
CDC42EP3	-0.025365
RPS9	0.025301
FAU	0.025274
GMFG	-0.025210
PRMT1	-0.025135
POMP	-0.025084
RPS21	0.025069
FLNA	0.025002
MRPL36	-0.024917
FDPS	-0.024807
RPS14P3	0.024790
GAS5	0.024779
FGL2	0.024779
ATP5F1	-0.024759
LSM4	-0.024678
FADS1	-0.024653
MAD2L1	-0.024647
ANP32B	-0.024591
GLO1	-0.024543
TGFBI	0.024494
UQCRQ	-0.024486
MS4A6A	0.024447
YWHAQ	-0.024427
BAX	-0.024409
MCM4	-0.024370
CREG1	0.024311
LY86	0.024268
TMED2	-0.024249
TOMM5	-0.024242
CXCR4	0.024119
RPL28	0.024102
RPS3	0.023821
GNG5	-0.023769
UBA52	0.023686
PKD1P1	0.023682
CCT7	-0.023595
GMNN	-0.023569
SLC25A5	-0.023411
RPS3A	0.023356
MRPL13	-0.023328
RPL10	0.023324
ARHGEF18	0.023314
NSA2	0.023309
TMSB10	0.023262
HNRNPAB	-0.023241
GOLPH3	-0.023224
PSMD8	-0.022996
TRA2B	-0.022936
MCM6	-0.022916
PHB2	-0.022911
SRGN	-0.022908
RPS17	0.022862
AARS	-0.022834
GSTP1	0.022815
DDIT4	-0.022722
EIF2S2	-0.022706
ACAT2	-0.022685
HEXB	0.022634
NUDT5	-0.022618
FCGR1B	-0.022605
SUSD1	-0.022567
SCD	-0.022509
RPL37	0.022479
PDIA6	-0.022457
CCNB1	-0.022456
RAD21	-0.022446
RPS16	0.022416
HNRNPC	-0.022400
SHFM1	-0.022164
VPS51	0.022116
ZFR	-0.022059
RILPL2	-0.022044
CCL5	-0.022033
CDC20	-0.021931
DHCR24	-0.021893
GINS1	-0.021825
RPS12	0.021741
CCR2	0.021684
BOLA3	-0.021667
COX8A	-0.021662
EXOC3	0.021650
SSB	-0.021648
YWHAE	-0.021629
PSMD14	-0.021578
HADHB	0.021574
RPS26	0.021558
GPX1	0.021503
NOP58	-0.021485
MRPS28	-0.021467
PTTG1	-0.021421
CDK5RAP3	0.021378
GTF3C6	-0.021333
HMGB2	-0.021316
PPP1CA	-0.021291
CYP1B1	0.021256
ITM2B	0.021240
VPS28	0.021161
NDUFAB1	-0.021157
LAMP5	0.021032
MORF4L1	-0.020979
CCT3	-0.020934
BIK	0.020881
YWHAG	-0.020866
HINT1	0.020836
ACLY	-0.020796
MIR155HG	-0.020700
CAP1	-0.020617
JUND	-0.020594
SERBP1	-0.020567
CALM2	-0.020556
SH3BGRL	0.020517
NHP2	-0.020512
UBA2	-0.020506
STAR	0.020496
VRK1	-0.020444
RAB27A	-0.020362
SNHG16	-0.020335
NGFRAP1	-0.020325
UBE2T	-0.020245
PARK7	-0.020228
RPS28	0.020217
ACAA1	0.020194
RNASEK	0.020179
STIP1	-0.020154
FCGRT	0.020147
EXOSC8	-0.020134
MCM3	-0.020107
VKORC1	0.020066
ETFA	-0.020065
PPP1CC	-0.020022
PRDX1	-0.019948
DNAJA1	-0.019836
MRFAP1	0.019797
BANF1	-0.019737
UBE2E1	-0.019713
RPL18	0.019675
IGFLR1	0.019670
UBE2M	-0.019661
SURF4	-0.019656
PGLS	0.019586
KIAA0101	-0.019575
SNRPF	-0.019547
RPN1	-0.019537
CCT5	-0.019500
S100A4	0.019488
PABPC4	0.019476
EIF4A2	0.019443
ACTR2	-0.019437
EMP3	-0.019432
SRP9	-0.019357
COX5A	-0.019343
RBX1	-0.019289
HNRNPR	-0.019279
RRM1	-0.019246
NAA38	-0.019104
TCP1	-0.018979
RPLP2	0.018923
HNRNPDL	-0.018878
BLVRB	0.018862
ZBTB33	0.018826
SUB1	-0.018803
SKA2	-0.018774
KLF10	0.018770
RNASET2	0.018770
RPS5	0.018711
ATP6	-0.018697
SLC39A4	-0.018609
UCHL3	-0.018589
CDK1	-0.018546
RFC4	-0.018532
CSE1L	-0.018500
POLD4	0.018486
IER2	-0.018456
CHMP2A	-0.018444
CACNA2D3	0.018433
RNASE2	0.018433
CACYBP	-0.018429
HIST1H2BK	0.018411
XPOT	-0.018279
TXN	-0.018271
CEBPB	-0.018270
ANP32E	-0.018251
P2RY8	0.018240
EIF3F	0.018231
PSMB1	-0.018224
ACSL1	-0.018206
HSD17B11	0.018186
LBR	-0.018046
PPIB	-0.018024
C14orf142	-0.018014
RPS11	0.018002
PSMB4	0.017999
KCNN2	-0.017938
MRPL18	-0.017932
DNAJB11	-0.017925
TNFSF13B	0.017882
PSMB6	-0.017865
RSRP1	0.017853
SQLE	-0.017851
SRSF1	-0.017831
CSF1R	0.017765
RPL13A	0.017735
MTHFD1	-0.017722
TPX2	-0.017709
GLRX5	-0.017707
UNG	-0.017684
DKC1	-0.017617
NUSAP1	-0.017497
UCK2	-0.017486
BRI3BP	0.017447
H2AFY	-0.017441
NUCKS1	-0.017420
LY75	0.017407
RPS18	0.017397
ACTG1	0.017370
MCM5	-0.017313
RABAC1	0.017272
HSPA4	-0.017189
HMGCR	-0.017171