!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	rat
!drug_name	Vitamin A
!smiles	OC/C=C(/C=C/C=C(/C=C/C1=C(C)CCCC1(C)C)\C)\C
!drugbank_id	DB00162
!cell_type	NA
!organism	rat
!end_metadata
KRT1	0.372614
MYLPF	0.208135
SPRR1A	0.193682
COL1A2	-0.174547
RPLP2	-0.160399
APOE	-0.160251
COX3	-0.155222
ACTA1	0.144514
ATP2A1	0.139669
ACTG1	0.135469
CKM	0.133687
ALDOA	0.123891
PABPC4	-0.121380
RPL28	0.120087
VIM	-0.116570
ND1	-0.111153
RPS16	-0.110119
KRT14	-0.109482
H19	0.107748
GAPDH	0.106285
RPS12	-0.104959
COL3A1	-0.104284
RPS10	0.100286
KRT34	-0.098162
RPSA	0.096925
RPL23	-0.096063
AHNAK	-0.094752
RPL6	0.093541
ANXA2	-0.092545
COL5A2	-0.092142
COL1A1	-0.089731
RPL9	-0.089469
DBI	0.088836
RPS29	0.087161
S100A4	-0.083709
ND4	0.081873
KRT5	-0.080311
FAU	-0.080197
POMP	-0.077500
ACTB	0.076225
RPS26	-0.075491
RPL27A	-0.075199
RPS21	-0.074859
SERPINH1	-0.073000
MYL1	0.071797
PADI3	0.069611
LUM	-0.069030
RPL22	-0.067820
TNNT3	0.064851
PCOLCE	-0.062709
CYTB	-0.060172
IVD	-0.060019
CST3	-0.059400
RPL19	0.059227
PPP1CB	-0.059074
HSPB1	0.058983
JUP	0.058351
CLU	-0.056367
RPL27	-0.055069
RPL12	0.054956
CALU	-0.054701
PPIA	-0.052806
HNRNPF	-0.052466
COX8A	-0.052145
MORF4L2	0.051149
ATP1B3	-0.047912
RPS3	-0.047880
EDF1	0.047540
RPS25	-0.047175
PRDX2	0.045649
RPL13A	0.044984
RPL10A	-0.044896
COX7A2	-0.044687
PFN1	0.044498
RPS17	-0.044279
TUBA1B	-0.043793
COL5A1	-0.043390
RPL7A	-0.043117
FABP4	0.043051
NDUFB4	-0.043042
SLC25A5	-0.042958
RPS23	-0.042778
BSG	0.042238
NDUFB2	-0.041689
S100A10	-0.041625
MMP14	-0.041512
COX2	0.041332
LGALS1	-0.041085
RPL18	0.040301
PMEPA1	-0.040269
TUBA1A	-0.039831
RPS13	-0.039595
CKB	0.039363
PLIN2	-0.039355
PVALB	0.039000
CD9	0.038524
MDH1	-0.038351
CCBL1	0.037965
TIMP2	-0.037767
ARF1	0.037401
ASS1	0.037169
LDHA	0.037108
LOX	-0.036273
RPL36AL	-0.036269
EEF1G	0.035974
GGH	0.035501
PYGM	0.035453
ATP6	0.034771
COX6A1	-0.034564
CALR	0.034273
ENO1	0.034269
CTSB	0.034055
TECR	0.033968
RPLP0	-0.033636
ATP5D	0.032416
NDUFB3	-0.031421
PTP4A2	-0.031258
PPP1CA	0.031136
ATP5G2	0.030812
ZFP36L1	-0.030485
NDUFV2	-0.030456
DCN	-0.030264
HACL1	-0.029870
NDUFB9	-0.029851
FABP5	0.029770
CAPN1	0.029684
SLC25A3	-0.029676
GJB2	-0.029582
LGALS3	0.029407
MGST1	-0.029236
NPM1	-0.028885
CSNK2B	0.028768
GPX4	0.028694
HNRNPK	0.028548
PTOV1	0.028466
PKM	0.028459
RPL10	-0.028441
BNIP3L	-0.028005
RPS8	0.027495
EIF2B4	0.027491
ARF4	-0.027473
PPP2R5A	0.026680
CBFB	-0.026637
COPZ1	0.026292
ACADM	-0.026008
HNRNPAB	-0.025820
MYL12B	-0.025654
PPIB	-0.025577
CASQ1	0.025352
PCNA	-0.025261
CTSK	-0.025111
PSMD11	0.024883
EGR1	-0.024556
RPS7	0.024386
RPL39	-0.024354
RPS4Y1	-0.024278
ARF5	0.024231
GRINA	0.024092
SPARC	-0.023838
TTC3	-0.023714
PRNP	-0.023506
USE1	-0.023291
KRT31	0.023241
ENTPD1	0.022949
PPP2CA	0.022792
RPS15A	-0.022758
SS18	-0.022730
COX7B	-0.022692
TUBA4A	0.022581
HSPD1	-0.022531
RPL14	0.022459
TUBB	0.022458
DAB2	-0.022107
RPL30	-0.022046
CRP	0.021957
RPS14	0.021823
ACY1	0.021595
NDUFA3	-0.021523
YBX3	0.021501
OAZ1	0.021378
KLF9	-0.021250
CCND2	-0.021231
SRSF11	-0.021077
NME1	0.020775
ACLY	-0.020655
RPL35	-0.020472
RPL37	0.020434
RPL11	-0.020239
EIF3B	0.020186
TPI1	0.020169
MPC1	-0.020149
MSX2	0.020107
ACSL5	-0.019966
METRNL	-0.019910
EEF1A2	0.019870
RPS27L	-0.019862
PHB2	-0.019680
PRDX1	0.019650
SLC25A4	-0.019509
LYPD3	0.019398
CORO1B	0.019342
UBC	-0.019282
MDH2	-0.019265
GABARAP	0.019217
NACA	-0.019184
COMT	-0.019183
AP2M1	0.019181
SDCBP	-0.019179
PDIA6	-0.019134
KLK6	0.019114
RPS6	0.018948
CLPB	0.018931
CABIN1	0.018691
PGAM1	0.018608
ARFGAP2	0.018607
BCAT2	-0.018506
B2M	-0.018471
GPX2	0.018460
LHX2	-0.018453
PSMB5	0.018428
ANAPC5	0.018418
GPC1	0.018299
PMP22	-0.018249
CTSD	0.018218
CD63	-0.018191
ATP5G1	0.018171
FSTL1	-0.017998
BATF3	0.017992
RPL4	0.017987
LYZ	-0.017925
INSIG1	0.017916
LAD1	0.017909
TNNI2	0.017877
IDH1	-0.017610
NDUFB6	-0.017575
ATP5B	0.017444
C1QBP	0.017362
CFL1	0.017356
ITPR3	-0.017297
MAP1LC3A	0.017256
RAB10	-0.017164
DCTN1	0.017163
PSME1	-0.017125
NFIB	-0.017123
RPL24	-0.017065
CRYAB	-0.016986
TKT	0.016930
THOP1	0.016918
TAF10	0.016855
FDPS	0.016708
ATP5H	0.016589
PSAP	-0.016325
ANXA5	-0.016297
PSMA4	-0.016212
SOSTDC1	-0.015905
ATP5A1	0.015801
F2R	-0.015618
KCTD15	0.015607
FBP1	0.015436
VPS4A	0.015403
MINPP1	0.015383
PPP1R2	0.015274
MYCBP2	-0.015266
DDRGK1	0.015081
GPX3	-0.015039
PSMB4	-0.015025
ATP6V1F	0.015006
SNN	0.014997
IFITM3	0.014993
GLOD4	-0.014975
ACTC1	0.014866
JUNB	0.014853
HMGA1	0.014825
DNPEP	0.014776
CSRP1	0.014737
HDLBP	-0.014726
KLK8	0.014694
NDUFS7	0.014677
AKR1A1	-0.014566
TXNIP	-0.014559
PNOC	0.014546
TMA7	-0.014470
BOK	0.014467
EIF4E	0.014446
LSAMP	-0.014429
COPZ2	-0.014370
NDUFA4	-0.014164
GPX1	-0.014136
CYTH2	-0.014129
YWHAZ	0.014071
PAIP1	-0.014032
SOD1	-0.013994
COX1	0.013985
CCNL1	-0.013938
IL1R2	-0.013932
EIF2B2	0.013887
EHD4	0.013866
TPT1	-0.013828
RNH1	0.013818
RNASE1	0.013710
PSMC1	0.013684
CREG1	0.013564
PLEKHA1	-0.013563
MBOAT7	0.013539
CPT2	0.013534
HR	0.013504
CACNA2D1	-0.013394
CCNG1	-0.013328
PDPN	-0.013267
APRT	-0.013240
GNB2	0.013213
YWHAH	-0.013195
NMU	0.013133
PREP	0.013118
COX5A	-0.013092
TUFM	0.013048
RAF1	-0.013044
TXNRD1	0.013025
ARF6	0.012986
FAM32A	0.012982
LBH	0.012899
LPL	-0.012894
HIGD2A	0.012857
RPL15	0.012849
HUWE1	0.012772
SMAD4	-0.012738
NAPA	0.012707
HMGCS1	-0.012683
FARSA	0.012658
LXN	-0.012657
NDUFA8	-0.012641
FIS1	0.012614
COX4I2	-0.012583
HELZ	-0.012557
HNRNPU	-0.012550
CRTAP	-0.012521
CNPY2	-0.012505
GPX7	-0.012504
RPN1	-0.012495
CRABP1	-0.012492
QDPR	0.012475
SH3GL1	0.012443
CRISPLD2	-0.012437
DIS3L2	0.012362
SEPW1	0.012358
SH2B1	0.012347
P4HA1	-0.012248
ACTA2	0.012244
MGST2	-0.012186
UNC119	-0.012135
LOXL1	-0.012132
PSME2	0.012088
BLMH	0.012001
POLR3A	-0.011997
RHOB	0.011965
STMN1	-0.011962
RPL17	-0.011959
CPA3	-0.011943
FUCA1	-0.011802
FAM162A	0.011759
CPD	-0.011755
CYCS	-0.011743
EIF2B5	0.011728
AHCY	-0.011707
PRKCDBP	-0.011679
SNCG	0.011632
ITGA1	-0.011609
HSD17B12	-0.011604
FOXQ1	0.011599
DOCK9	-0.011597
ENO3	0.011582
SYT5	-0.011510
DYNLRB1	-0.011497
EIF5B	-0.011468
CFD	0.011468
FBLN5	-0.011441
ID1	0.011440
ACAA2	0.011396
SRPX	-0.011382
CPT1A	0.011247
PI4KB	0.011241
RPS11	-0.011225
SNRNP70	-0.011192
SHFM1	0.011153
IGF2R	-0.011121
AP2S1	0.011106
ARPC1B	-0.011081
MPHOSPH8	0.011055
MYLK2	0.010958
GDA	-0.010941
PGRMC1	-0.010925
CDC34	0.010910
RPL21	0.010910
STAT5B	0.010904
VAMP3	-0.010868
HIST1H2AJ	0.010847
FAM111A	0.010834
LRRC59	-0.010786
RBBP7	-0.010773
CRABP2	0.010756
BRAP	0.010745
CHMP2A	0.010740
TDO2	-0.010731
CR1L	-0.010720
DDOST	-0.010710
TAF6	-0.010675
GSK3A	-0.010670
SEC31A	-0.010670
GRB10	-0.010665
FLNB	0.010661
SMARCD2	-0.010644
SCAMP2	0.010642
SLC25A11	0.010617
VCAN	-0.010594
UQCC2	0.010569
APOD	0.010530
RAB11A	0.010530
SEC61B	-0.010527
ATP5O	0.010512
RBP1	0.010470
SDHA	-0.010466
HSPB6	-0.010425
ESPN	-0.010418
OAT	-0.010415
NDUFS8	0.010388
TAGLN3	-0.010263
BCKDHB	-0.010238
MXD4	-0.010233
ITM2B	0.010211
SLC7A2	0.010177
SLC35B1	0.010176
AES	0.010134
TTLL5	0.010126
LAMTOR1	0.010042
ORAI1	0.010034
AXIN1	0.010026
ATP9B	0.010013
HMGCS2	-0.010006
PAPSS1	0.010005
SEPP1	-0.009982
SLC40A1	0.009976
PTGR1	0.009968
HSP90B1	-0.009922
NRD1	0.009911
DUSP6	0.009886
CITED1	0.009859
CSDC2	0.009855
DYNLL1	0.009847
SERBP1	-0.009837
CSNK1A1	0.009830
NELL2	-0.009818
PPT2	0.009814
PDLIM2	0.009787
KLF6	-0.009742
EIF4H	0.009700
NOP58	-0.009650
SUB1	-0.009602
NDUFA5	-0.009599
CTSC	0.009570
FCGRT	-0.009532
GNAI2	-0.009505
PDAP1	0.009502
RAB6A	-0.009497
TRAPPC3	-0.009496
URGCP	0.009492
TGM1	0.009489
NINJ1	0.009488
NDUFC1	-0.009467
ACTN2	0.009451
EFTUD2	0.009410
LENEP	0.009398
SDC4	-0.009360
NDUFB10	0.009352
ACADVL	0.009336
TEF	-0.009315
BGN	-0.009303
SMPX	0.009302
FAM229A	-0.009296
H1F0	0.009252
AP1B1	0.009240
MAN2C1	0.009236
ITFG3	0.009230
CAV1	-0.009205
EIF3M	-0.009185
UBE2I	-0.009179
H2AFX	0.009174
GDI2	0.009142
CTDSP1	-0.009127
CD74	-0.009107
SLC22A1	0.009091
C1QB	0.009075
ARL4A	0.009072
SLC6A8	0.009048
TMEM47	-0.009040
MC3R	0.009026
PEBP1	0.009023
GABARAPL2	0.008999
SLC8A1	-0.008967
CS	0.008957
RAB5A	0.008943