!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!drug_name	Doxycycline
!smiles	CC1C2C(C3C(C(=O)C(=C(N)O)C(=O)C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)N(C)C)O
!drugbank_id	DB00254
!pubchem_cid	5281011
!cell_type	RT112 cancer cell line (FGFR3 knocked down with shRNA 6-16)
!organism	human
!end_metadata
EPHX4	-0.127780
KDELC2	0.097583
DCP1B	-0.091195
C1RL	-0.089457
CNN3	-0.073354
ARMCX3	-0.071879
TMEM139	-0.069209
PTX3	-0.063990
FABP5	0.059466
IFI44L	-0.058872
AOC1	-0.058808
NID1	-0.058412
GSAP	-0.056308
C16orf54	-0.056249
MMP1	0.055401
ARHGEF6	-0.055086
PCDHB2	-0.054554
QPRT	-0.053790
PADI3	0.052585
EFEMP1	0.051645
MEIS3P1	-0.051609
EPDR1	-0.051215
EPHA7	-0.049810
PROS1	-0.047675
TRIP6	-0.047457
LIPG	0.047150
PLAGL1	-0.046261
CRISP3	-0.045731
LOC728613	-0.045515
ARMCX6	-0.045374
HSD17B2	0.044920
FAM221A	-0.044752
LRRN1	-0.043643
HCLS1	-0.043104
MAGEA6	0.043029
GPX3	-0.042861
PLSCR4	-0.042806
HIST1H2BG	-0.041937
SLC1A6	0.041456
ROBO1	-0.041454
GIMAP2	-0.041103
SCNN1B	-0.040476
CCL26	-0.039352
SORD	0.039092
FUT11	-0.038469
CALB1	-0.038440
GABRP	0.038346
MICALCL	0.038327
SEPP1	-0.038114
MDK	-0.038069
S100A8	0.037709
PVRL3	-0.037358
RBM11	-0.036841
MMP10	0.036824
ANKRD6	-0.036823
FAM198B	-0.036503
NDN	-0.036121
CLIC3	0.035967
TCAM1P	-0.035658
IGFBP6	0.035617
SULF2	0.035107
TP53	-0.035082
FAM129A	-0.034843
RYR1	-0.034597
LOC100507557	-0.034358
PODXL2	-0.034228
PLAU	0.034200
SLC20A1	0.034041
VMP1	0.033945
ZNF415	-0.033669
LOC728819	-0.033036
MUM1L1	0.032665
BDH2	-0.032536
RTP4	0.032488
S100A4	-0.032193
MMP12	-0.032191
TMEM55A	-0.031882
CCZ1B	0.031600
LCN2	0.031277
ANO1	0.031190
NUAK1	0.031025
C9orf64	-0.030993
TMEM27	-0.030992
ERP27	-0.030713
RAB36	0.030713
DEPDC7	-0.030673
LOC729088	-0.030445
SAMD13	-0.029265
LY96	-0.029191
CDH5	0.029161
DPEP2	-0.029090
SPP1	-0.028955
APCDD1	0.028793
LGALS1	-0.028787
MAN1A1	-0.028683
HMGCS1	0.028675
IFI27	-0.028625
S100A9	0.028240
IFI6	-0.028199
DUSP6	0.028140
PCOLCE2	0.028116
MAGEA3	0.027924
GALM	-0.027889
ITLN1	-0.027831
ID4	-0.027754
SUSD5	0.027455
C15orf48	0.027294
CYP1B1	-0.027211
LINC00487	-0.027029
LINC01279	-0.027002
ABCG2	0.026981
TNFRSF1B	0.026919
EEF1A2	-0.026838
GHDC	-0.026820
LBH	-0.026773
ASB9	-0.026757
MSMO1	0.026678
DHX40	-0.026613
WLS	-0.026554
HLA-DMA	-0.026384
PDZK1	-0.026381
SOX9	0.026272
TMEM231	-0.026175
PDGFC	-0.026101
HSPA1A	-0.026052
NGFR	0.026038
SMKR1	-0.025972
MIR21	0.025737
LOC100505728	-0.025484
LOC439938	-0.025444
ZNF229	0.025403
CP	-0.025333
RRAGD	-0.025248
BEX4	-0.025184
XK	-0.025097
KRT5	0.025031
SLC16A7	-0.024782
BAALC	-0.024758
CLCA4	-0.024644
BPIFB1	0.024630
NME1	0.024493
GNG4	0.024460
ANXA10	-0.024450
SECTM1	-0.024388
ZDHHC8P1	-0.024319
LRP8	0.024206
RHOBTB1	-0.024196
SPATA17	-0.024142
HMX2	-0.024098
LOC400541	0.024039
CUX2	0.024003
TM4SF1	0.023934
COL4A4	0.023920
CPLX1	0.023884
RASA4	-0.023860
KRT16	0.023841
HAND2	0.023779
TNFRSF21	0.023688
DUSP9	0.023605
CEACAM6	0.023556
LAMP3	-0.023544
MICAL2	0.023541
CCDC85A	-0.023359
PLBD1	-0.023352
TTC13	0.023308
ECI2	-0.023297
LY6D	0.023279
IFIT1	-0.023249
CCDC69	0.023228
MICB	0.023159
COCH	-0.023059
GADD45A	0.023043
ACLY	0.022961
SPINK4	-0.022952
GAMT	-0.022915
MAP2	-0.022908
SMIM22	-0.022825
SLC2A6	0.022811
SVOPL	-0.022798
NAP1L5	-0.022740
LINC00525	-0.022729
GPCPD1	0.022721
SMAD7	-0.022671
UPK1A	-0.022602
PRICKLE1	-0.022587
F13B	-0.022544
DEPDC1-AS1	-0.022471
GPR34	-0.022380
SCNN1G	-0.022363
SHF	-0.022353
C6orf57	-0.022351
HOXA5	-0.022307
SDR16C5	0.022235
NMNAT2	0.022188
IRS1	-0.022171
LOC100505716	-0.022158
LY6G5C	0.022130
LRRC2-AS1	0.022123
CTPS1	0.022108
NMB	-0.022045
C8orf4	0.021997
DPY19L2P2	-0.021994
SDC2	-0.021907
MCOLN3	-0.021890
HEATR3	0.021819
LINC01106	0.021770
SOX5P	0.021759
ANKRD22	0.021724
UBE2E2	-0.021720
SLC30A10	-0.021711
CYP4X1	0.021690
LINC00669	-0.021663
DEGS2	0.021651
MVD	0.021641
CCDC80	-0.021549
GABRE	0.021510
SLC35G2	-0.021399
NEAT1	0.021393
PKN3	-0.021349
PLEKHS1	0.021325
HIST1H4L	-0.021212
BST2	0.021204
GRHL3	0.021129
SMPD3	0.021109
FGFBP1	0.021103
AK1	0.021094
ST7-OT4	0.021041
FGF13	-0.021038
LINC00305	-0.021033
RGPD1	0.021025
CCDC144B	-0.021018
LOC100505501	-0.021018
PMAIP1	-0.020998
RNF144A	-0.020900
LSS	0.020899
CCDC151	-0.020881
HOXD12	0.020877
LURAP1L	-0.020857
STS	0.020839
EVA1A	-0.020837
JAG1	-0.020756
HCK	-0.020738
F3	0.020727
PLA2G4A	-0.020721
FAM89A	-0.020711
EMR3	-0.020693
ARHGEF3	-0.020672
IL13RA2	-0.020608
SMAD1-AS2	-0.020541
LMNTD2	-0.020534
PHKA1-AS1	0.020527
IFITM1	-0.020518
LOC102724612	0.020473
CELF6	-0.020405
IZUMO1	0.020360
GPR85	-0.020356
SERPINH1	-0.020314
EMB	-0.020314
FDFT1	0.020310
LOC101929645	-0.020306
KLF1	-0.020293
HIST1H2BC	0.020291
TG	-0.020260
OLIG1	0.020223
PAM	-0.020203
TMC4	-0.020176
MCMDC2	-0.020161
SERPINB2	0.020139
HMGCR	0.020107
LOC375196	-0.020099
TMEM132D	-0.020083
MYO5C	-0.020020
TSPAN12	0.019993
C12orf5	0.019973
PRM2	0.019961
TMPO-AS1	-0.019956
ST6GALNAC1	0.019929
SERPINB11	-0.019924
C15orf52	0.019893
LOC100129973	-0.019880
PCLO	-0.019858
XDH	0.019849
CTSD	0.019770
RPS6KB2	0.019750
CCNJL	0.019748
FEZ1	-0.019743
F9	-0.019736
INAFM2	0.019706
LOC101928333	-0.019697
FNDC1	-0.019656
WBSCR28	0.019624
MSRA	0.019545
LINC00567	-0.019514
C15orf56	-0.019508
LOC101929680	-0.019504
ALDH3A1	-0.019494
HDX	-0.019443
TCEAL8	-0.019439
HIST1H4C	-0.019434
LOC100128727	-0.019422
LOC283270	0.019413
MAGED2	-0.019396
ABCG1	0.019392
LINC00543	-0.019381
IRF9	-0.019285
MAGEB18	0.019244
LPAR3	0.019220
CDCA7	-0.019147
CYCS	0.019141
MEIS2	-0.019125
ENPP5	-0.019112
HIST1H2AM	-0.019079
BCAS2	0.019079
KANSL1-AS1	-0.019064
MIR205HG	0.019015
PIWIL4	-0.018999
AIM2	0.018960
IGFBP2	-0.018934
DHCR7	0.018897
INSIG1	0.018893
NCF2	0.018869
GPR116	-0.018858
GGT7	-0.018856
IL7	0.018854
SQLE	0.018845
IL25	-0.018827
PCSK9	0.018825
SLC7A5	0.018821
SRM	0.018820
LOC100130219	-0.018789
DENND5A	0.018768
PDE8B	-0.018734
SMIM1	-0.018733
TCF24	-0.018711
OXGR1	-0.018668
UBE2G2	0.018626
C5orf30	-0.018621
MAP7D2	-0.018611
GPNMB	-0.018610
CHUK	0.018521
WNT5B	-0.018514
ABCD3	0.018497
C1orf64	-0.018467
ACAT2	0.018451
CDH13	0.018389
NT5M	-0.018376
NEK10	0.018357
CERS1	-0.018357
LRRK1	-0.018343
FOXL2	0.018336
C18orf12	-0.018310
LOC152225	0.018308
SEMA3D	-0.018299
SLC25A21-AS1	-0.018298
HCP5	-0.018297
ACSL1	0.018292
PHF5A	0.018285
FOXF1	-0.018248
HMGN5	-0.018184
PAN3-AS1	0.018168
LOC541473	-0.018162
GPR115	0.018155
TFRC	0.018145
TRPC5OS	-0.018131
HTR2C	-0.018130
CASP4	0.018108
UPK2	0.018099
TMEM138	0.018067
PLAT	0.018049
IQGAP2	-0.018041
KBTBD11	0.018015
VSIG2	-0.017986
MYH7B	0.017968
PIWIL1	0.017962
LOXL1	0.017954
TTTY15	-0.017930
RIIAD1	-0.017857
VWDE	0.017832
PSCA	0.017830
ZCCHC12	-0.017830
GPR1-AS	-0.017821
KLRAP1	-0.017819
PYCARD	0.017812
C1orf216	0.017811
C1orf220	-0.017806
C14orf93	-0.017805
SPINK5	0.017796
PARD3-AS1	-0.017777
TMLHE	-0.017773
HCFC1R1	-0.017756
BTBD11	-0.017751
ZNF182	-0.017738
CST6	0.017729
ID2	-0.017722
C20orf141	0.017719
PLA2G16	-0.017715
ZNF624	-0.017663
PLXNB3	-0.017629
H19	-0.017622
LRIT1	-0.017605
MT2A	-0.017596
LOC102800447	0.017553
BIN3-IT1	-0.017549
CCDC84	0.017529
SOX12	-0.017509
ZNF423	0.017483
AGTRAP	-0.017465
PXYLP1	0.017445
STK24-AS1	0.017420
LOC101929144	0.017404
CPS1	-0.017342
GPX8	-0.017311
ZMPSTE24	0.017267
DHCR24	0.017265
GJB6	0.017243
PTPRM	0.017240
PIGW	0.017224
FGFR3	0.017199
SLC48A1	0.017198
AKAP4	0.017178
ST7-AS1	0.017170
CBX3P2	0.017160
ZNF137P	0.017155
THAP9-AS1	0.017133
G6PD	0.017128
HEPACAM2	0.017104
TMEM121	-0.017099
POU6F2-AS2	-0.017097
APOA4	0.017088
PRR15L	0.017087
OVOS2	-0.017082
ALPP	0.017055
SLC9A3R1	0.017049
CNGA1	-0.017046
BTN3A3	-0.017040
RLN2	-0.017037
CBWD1	0.017026
ABCA17P	-0.017014
SLC25A44	0.017005
LRGUK	0.016983
ACOT6	-0.016974
LOC100131262	0.016966
TBC1D28	-0.016959
GDA	0.016941
NRG4	-0.016932
ZSCAN31	-0.016902
NDRG1	-0.016892
MRC1	-0.016874
LINC00935	0.016856
SEMA3A	-0.016836
LOC101928940	-0.016834
CYP24A1	-0.016830
TTC39B	-0.016823
PNRC1	-0.016801
SMCO4	-0.016774
HES4	-0.016751
PSORS1C2	-0.016750
RAB34	-0.016750
NRGN	-0.016745
KCTD6	-0.016709
C7orf31	-0.016660
ORMDL2	0.016651
MARVELD1	-0.016644
LOC284513	0.016601
MARS	0.016598
CHAC2	0.016595
TRIM64EP	0.016586
PRSS16	-0.016569
SLC47A2	-0.016558
LOC100272216	0.016545
MS4A6E	-0.016544
NOP2	0.016540
CD68	-0.016536
GLUL	0.016526
LOC101929229	-0.016504
ARHGEF7-AS2	-0.016496
PRKXP1	-0.016476
C10orf55	0.016475
MALAT1	0.016470
MTMR6	0.016463
CTB-174D11.1	-0.016449
LOC101928161	-0.016434
MATN1-AS1	-0.016423
JPH1	-0.016419
SOX30	-0.016417
CUTC	0.016411
HTN3	0.016388
TOB1-AS1	-0.016364
FAM134B	-0.016355
CTSF	-0.016355
C1R	-0.016355
ETV4	0.016352
NDUFS6	0.016344
VASN	-0.016331
PPP2R2B	-0.016328
TRIM16L	-0.016323
VTCN1	-0.016314
MAPK7	-0.016314
CTSO	-0.016289
CYP2J2	-0.016283