!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	mouse
!drug_name	Fasudil
!smiles	C1CNCCN(C1)S(=O)(=O)C2=CC=CC3=C2C=CN=C3
!pubchem_cid	3547
!cell_type	Forebrain astrocytes - 2 Hours
!organism	mouse
!end_metadata
ERRFI1	-0.082386
CHAC1	-0.073512
DNAJB1	-0.068816
SGK1	-0.068752
BTG1	-0.065341
ARNTL	-0.062343
RGS16	-0.061010
RASL11A	-0.059818
MVD	-0.059442
RASL11B	-0.058263
JUN	-0.058050
PHLDA1	-0.057807
SERTAD1	-0.056460
GADD45B	-0.055605
SCG2	-0.054870
CCRN4L	-0.054314
OSGIN1	-0.054093
RND3	-0.053974
PLEKHF1	-0.053750
CEBPB	-0.053672
SPSB1	-0.051148
KLF5	-0.050858
NEDD9	-0.050755
ATF4	-0.050679
GADD45A	-0.050297
CDCA4	-0.050166
CDK5R1	-0.050045
CXCR4	-0.050018
SNIP1	-0.049852
PTX3	-0.049754
STK17B	-0.049274
VGF	-0.049242
BHLHE40	-0.048891
VASN	-0.048147
ZNF655	-0.048053
FZD7	-0.047968
DYRK3	-0.047863
NUP62	-0.047849
MAP2K3	-0.047698
ZNF282	-0.047430
TRMT10C	-0.047334
CMTR2	-0.046923
EGR2	-0.046878
PPP1R3C	-0.046753
BDNF	-0.046673
HR	-0.046251
SRF	-0.045906
TRIB2	-0.045879
IL11	-0.045783
TOB1	-0.045317
FHL2	-0.045246
ZNF597	-0.045139
OTX1	-0.045071
TOPORS	-0.044931
SPHK1	-0.044731
USP2	-0.044711
CDC42EP3	-0.044627
CHST3	-0.044585
SOCS3	-0.044471
IPPK	-0.044356
PHOSPHO2	-0.043555
DDIT4	-0.043410
LIF	-0.042914
ITPKC	-0.042714
CSRNP2	-0.042649
HBEGF	-0.042494
ETS2	-0.042380
HK2	-0.042335
STARD4	-0.042334
XBP1	-0.042322
ARL4C	-0.042150
RHOB	-0.041574
ATF3	-0.041552
GATA2	-0.041508
CISH	-0.041474
ZNF623	-0.041471
KLF3	-0.041436
DUSP1	-0.041238
FOSL1	-0.041171
TNFRSF12A	-0.041074
DUSP7	-0.040705
ZFPM1	-0.040674
SH3BP2	-0.040630
CYP51A1	-0.040557
FEM1B	-0.040266
TEFM	-0.040138
MCL1	-0.040134
SNX16	-0.040133
SKIL	-0.039993
HERPUD1	-0.039979
FHDC1	-0.039928
GBX2	-0.039593
SOCS5	-0.039503
ZSCAN12	-0.039490
NGF	-0.039419
PLEKHF2	-0.039074
PLK2	-0.039073
MAT2A	-0.039009
IER3	-0.038959
SRXN1	-0.038776
HSD17B7	-0.038683
RNMTL1	-0.038435
RNF19A	-0.038344
SOX21	-0.038336
THUMPD1	-0.038253
HPS6	-0.038182
PIM3	-0.037833
EPC1	-0.037787
CHST8	-0.037660
BET1L	-0.037370
PDGFB	-0.037280
ID1	-0.037265
BCL6	-0.037213
TGIF1	-0.037194
IRS2	-0.037193
KLHL21	-0.037074
KLF6	-0.036987
CTGF	-0.036894
SDE2	-0.036785
FAM167A	-0.036737
DOK1	-0.036638
PLAGL2	-0.036622
CLCF1	-0.036519
SLC25A25	-0.036472
STK40	-0.036427
NFKBIZ	-0.036406
PRMT6	-0.036335
PES1	-0.036254
TRIM47	-0.036080
ENC1	-0.036001
IRX3	-0.035989
STAC	-0.035900
C14orf169	-0.035896
RHOU	-0.035734
CDT1	-0.035665
ZNF18	-0.035557
ZNF574	-0.035453
INSIG1	-0.035359
SOX2	-0.035286
MFSD2A	-0.035264
PPP1R15A	-0.035233
FOXC1	-0.035190
ZBTB7C	-0.035171
FOXO1	-0.035077
INTS12	-0.035076
LDLR	-0.034834
LSS	-0.034821
TRMT61A	-0.034724
PELO	-0.034593
ZBTB24	-0.034579
CDR2	-0.034394
KCNK13	-0.034225
MLYCD	-0.034218
WNT7A	-0.034211
VEGFA	-0.034158
MAD2L1BP	-0.033947
MIDN	-0.033917
EVA1C	-0.033883
HILPDA	-0.033809
EGR1	-0.033765
MSMO1	-0.033743
EXO5	-0.033726
ANKRD49	-0.033609
GDF15	-0.033564
PPCS	-0.033546
BCOR	-0.033506
DLX1	-0.033392
NOG	-0.033306
ZNF91	-0.033294
KLF2	-0.033292
KLF9	-0.033287
DBR1	-0.033139
RABGEF1	-0.033129
UBTD1	-0.033076
ZNF436	-0.032962
GLDN	-0.032670
FLRT3	-0.032634
NUPR1	-0.032577
PDCD7	-0.032510
DIRAS2	-0.032474
FBXO34	-0.032473
VPS37B	-0.032373
GSE1	-0.032345
KDM6B	-0.032338
SIAH1	-0.032324
HSPB1	-0.032266
CD3EAP	-0.032231
HEXIM1	-0.032231
ZNF672	-0.032226
FST	-0.032206
KBTBD2	-0.032141
FBXO33	-0.032051
FDPS	-0.031973
RUNX1	-0.031962
ELL	-0.031915
DHCR7	-0.031879
CCDC130	-0.031833
ZNF12	-0.031788
SCX	-0.031764
BAG3	-0.031689
GFPT2	-0.031684
CCDC174	-0.031683
SMAD1	-0.031678
SMARCAD1	-0.031661
ZNF394	-0.031541
CCDC86	-0.031497
LIMK2	-0.031391
RBM48	-0.031376
AHDC1	-0.031358
RIN1	-0.031328
FBXO32	-0.031265
GRWD1	-0.031191
KCTD15	-0.031085
RFXAP	-0.031058
CTTNBP2NL	-0.031017
SEMA4B	-0.030997
SOX8	-0.030991
RASSF1	-0.030888
NUPL2	-0.030885
GSPT2	-0.030814
FAM207A	-0.030792
RGS17	-0.030727
DTX2	-0.030517
GPR123	-0.030516
DDX28	-0.030489
SLC35C1	-0.030418
EDN1	-0.030312
BCL2L1	-0.030310
PPM1D	-0.030268
FOXG1	-0.030226
ZNF639	-0.030168
ACTA1	-0.030166
SNRK	-0.030157
RBAK	-0.030121
ZNF212	-0.030098
NOTCH1	-0.030039
NRBF2	-0.030024
RPP25L	-0.029972
AATK	-0.029905
BCAR1	-0.029865
FAM181B	-0.029850
NR2C2AP	-0.029754
ZNF281	-0.029745
FIZ1	-0.029741
TUT1	-0.029611
DDX20	-0.029565
ZNF585A	-0.029372
PLK3	-0.029306
FBXO30	-0.029169
NFKBIA	-0.029029
DMRTA2	-0.028941
SLC35E4	-0.028932
TIRAP	-0.028880
KTI12	-0.028877
DOK4	-0.028842
NOP58	-0.028836
CCNO	-0.028806
HMGA1	-0.028784
MAPK6	-0.028783
PUS3	-0.028741
ZNF717	-0.028720
HMGXB3	-0.028616
MAK16	-0.028591
TOB2	-0.028567
NFIL3	-0.028523
USP47	-0.028465
GNL3	-0.028387
LARP6	-0.028366
TMEM11	-0.028317
MICALL2	-0.028308
PHC2	-0.028291
CASC3	-0.028251
SERTAD4	-0.028240
BRD2	-0.028189
DLX2	-0.028183
PCGF1	-0.028175
ETAA1	-0.028171
PAPD7	-0.028162
MAFF	-0.028139
MOB3A	-0.028101
PIK3R1	-0.028091
BAHD1	-0.028091
SIRT1	-0.028085
CITED2	-0.028074
NUAK1	-0.028030
FAM222B	-0.028010
NAV1	-0.027997
ITGA5	-0.027862
TMEM185B	-0.027859
MARS2	-0.027837
BRIX1	-0.027780
RPP38	-0.027695
FBXL14	-0.027598
CHCHD4	-0.027570
EVA1A	-0.027538
IDI1	-0.027534
PPTC7	-0.027525
AACS	-0.027458
MTERF	-0.027343
ATG16L1	-0.027331
KCNF1	-0.027272
ZBTB21	-0.027243
NOTUM	-0.027214
FAM110A	-0.027083
RNF219	-0.026943
MKRN3	-0.026941
ZFP64	-0.026931
MED7	-0.026900
NHLRC1	-0.026884
YRDC	-0.026878
PIK3CB	-0.026852
ORAOV1	-0.026837
KCTD5	-0.026756
DENND3	-0.026693
ZNF770	-0.026586
EPC2	-0.026516
PDGFA	-0.026511
KATNBL1	-0.026387
CDCA7	-0.026342
P2RY1	-0.026307
PSMG3	-0.026281
EIF1AX	-0.026244
FAM160B1	-0.026197
CREB3L2	-0.026105
MAP3K11	-0.026104
ETS1	-0.026086
ZXDC	-0.026084
ADAMTS1	-0.026075
DUSP6	-0.026055
C3orf38	-0.026034
CIRH1A	-0.026013
ZFX	-0.025998
TBC1D10A	-0.025917
ZBTB2	-0.025887
SRFBP1	-0.025819
SYVN1	-0.025818
BRF2	-0.025812
CCDC85B	-0.025782
FASTKD5	-0.025776
NMU	-0.025726
NDUFAF4	-0.025699
FAM203A	-0.025678
ELOVL6	-0.025660
MAPKAPK3	-0.025641
RAB3IP	-0.025640
PDCD2	-0.025631
GPR19	-0.025577
MED8	-0.025542
PDLIM7	-0.025523
ID2	-0.025483
PDE12	-0.025462
FASTKD3	-0.025460
TNRC6A	-0.025415
YTHDF2	-0.025399
ZNF644	-0.025391
ADNP	-0.025370
LMNA	-0.025310
IFFO2	-0.025300
RNF113A	-0.025281
ARC	-0.025211
EIF4ENIF1	-0.025180
NDEL1	-0.025149
LPAR6	-0.025134
MLLT11	-0.025009
COQ10B	-0.025003
C1QB	0.024976
ZCCHC14	-0.024907
CYR61	-0.024899
COA4	-0.024855
RCL1	-0.024837
NOP56	-0.024810
MED18	-0.024787
RNF182	-0.024767
ZDHHC13	-0.024740
NMD3	-0.024686
SYT4	-0.024664
TBC1D1	-0.024653
ANKRD54	-0.024634
CXCL10	-0.024608
LYSMD4	-0.024605
MDM2	-0.024592
MED26	-0.024581
RUSC2	-0.024562
MPHOSPH6	-0.024557
KCNC4	-0.024535
PROSER1	-0.024530
HS6ST1	-0.024521
NXT1	-0.024503
FNIP1	-0.024469
FCER1G	0.024464
ZBTB7A	-0.024428
MAP2K4	-0.024415
LENG9	-0.024396
ZYX	-0.024392
SPSB2	-0.024383
LAMC2	-0.024355
KIAA0355	-0.024328
MTSS1	0.024317
BAG5	-0.024226
AFTPH	-0.024192
TPRN	-0.024143
PIAS1	-0.024063
CSRP2BP	-0.024021
ID3	-0.023954
TAF5L	-0.023933
BUD13	-0.023898
AREG	-0.023895
NET1	-0.023814
MCAM	-0.023783
PQLC1	-0.023764
WDR74	-0.023755
C1QC	0.023737
GTPBP4	-0.023737
RAE1	-0.023720
IFRD1	-0.023717
PAPOLG	-0.023702
METAP1	-0.023678
SNX11	-0.023659
LAPTM5	0.023632
KAT5	-0.023615
PYGO2	-0.023596
JUNB	-0.023534
ZNF691	-0.023481
MSX2	-0.023449
VSTM2B	-0.023447
WISP1	-0.023400
ZNF451	-0.023356
NOP2	-0.023341
PHLDA3	-0.023334
PCGF5	-0.023313
ZNF213	-0.023306
CWC22	-0.023266
SOX9	-0.023261
VPS18	-0.023259
RAB40C	-0.023211
RASA2	-0.023210
SMAD6	-0.023189
ARHGAP22	-0.023120
NIFK	-0.023087
NOB1	-0.023085
PQLC2	-0.023082
TIGD2	-0.023056
LUZP1	-0.023027
PLEKHG2	-0.023024
SLX4	-0.023024
NGDN	-0.023019
MORC2	-0.023002
DLK1	-0.022998
CD53	0.022980
SYN2	-0.022946
MAP3K1	-0.022895
SMUG1	-0.022869
HMOX1	-0.022810
RAI14	-0.022734
FLCN	-0.022693
ZC3H10	-0.022685
CSTF1	-0.022666
SQLE	-0.022604
PIAS4	-0.022592
C18orf21	-0.022562
LURAP1L	-0.022547
COL4A2	-0.022539
EXOSC4	-0.022536
PLCD3	-0.022530
ZFP3	-0.022411
DUSP4	-0.022410
ACSL3	-0.022403
SERTAD3	-0.022381
TMEM41B	-0.022354
HS3ST3A1	-0.022308
FAM53C	-0.022262
GUCD1	-0.022211
C17orf80	-0.022211
SERTAD2	-0.022200
ZNF35	-0.022183
C17orf85	-0.022179
DDX27	-0.022160
SLC20A1	-0.022155
LPIN1	-0.022100
ZSWIM1	-0.022077
ZSWIM4	-0.022042
C11orf68	-0.022039
DAB2IP	-0.022021
EGR4	-0.022000
NOL10	-0.021988
MSX1	-0.021958
RNF4	-0.021947
ZNF710	-0.021926
LAMC1	-0.021914
DDIT4L	-0.021907
PHACTR4	-0.021889
NAB2	-0.021863
TATDN2	-0.021840
FAM214B	-0.021837
TBP	-0.021826
VANGL1	-0.021818
ZNF768	-0.021815
NRF1	-0.021798
ZNF32	-0.021787
SEC24B	-0.021752