!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!organism	Homo sapiens
!cell_type	MCF7cells
!pert_name	estradiol
!pert_id	PubChemCID:5757
!organism	human
!pert_type	chemical
!end_metadata
AMZ1	0.072172
KRT13	0.070008
PGR	0.066499
GREB1	0.065178
RET	0.064217
PGR	0.061814
GREB1	0.060027
RBM24	0.056278
SGK3	0.055411
HEY2	0.053788
MYB	0.053155
PSCA	-0.052185
CXCL12	0.052036
AREG	0.049780
AREG	0.049101
MYBL1	0.049069
CA12	0.049060
GRHL3	-0.048037
ALDH1A3	-0.046215
SLC1A1	0.046202
PKIB	0.045829
RAPGEFL1	0.045560
COL12A1	0.045157
HSPB8	0.043982
IGFBP4	0.043642
TP53INP1	-0.043551
XBP1	0.043491
CDCA7	0.043096
CISH	0.042559
NPY1R	0.041648
SLITRK4	0.041559
NXNL2	0.041077
SYNDIG1	0.039889
ANKRD35	-0.039155
CFL1	-0.039083
BMF	-0.039025
AGR3	0.038972
SGK1	0.038881
CXCL12	0.038878
TP53INP1	-0.038622
SALL4	-0.037931
RASGRP1	0.037760
SEC14L2	0.037260
SFXN2	0.037098
MYC	0.037038
ADCY1	0.036962
LIPH	-0.036353
TMEM164	0.036025
FMN1	0.036018
DHRS3	-0.035880
KIAA0226L	0.035872
PPIF	0.035809
SLC47A1	0.035801
DEPTOR	0.035027
GPR68	0.034730
STON1	-0.034603
MAMLD1	0.034367
NXNL2	0.034347
DDX10	0.033892
METTL1	0.033846
NOP16	0.033304
HCAR3	-0.033261
RERG	0.033236
RET	0.033191
BTG2	-0.033110
HCAR1	-0.032973
TSC22D3	-0.032954
ADAMTS9	0.032944
LAMA3	0.032918
SLC7A5	0.032828
KCNK6	0.032682
RRS1	0.032680
METTL1	0.032606
SYTL4	0.032386
LOXL3	0.032358
FAM84A	-0.032068
RNF43	-0.031792
RAB31	0.031541
WNT11	-0.031314
MAPT	0.031203
NR5A2	0.031141
FABP5	0.030966
FJX1	0.030952
DTL	0.030861
SIDT1	-0.030724
STC2	0.030659
ABCA1	-0.030653
IL17RB	0.030616
KCNK5	0.030512
ECE2	0.030459
SYTL5	0.030453
MYBL1	0.030400
RAB27B	-0.030342
CALCR	0.030251
PLAC1	0.030242
CDK6	-0.030084
DDX21	0.030057
TMEM120B	0.029993
FABP5	0.029991
BMP6	0.029877
DOK1	0.029787
CA5B	-0.029722
NRP1	-0.029655
GPATCH4	0.029432
NR4A3	0.029351
NAT8L	0.029215
CA2	0.029129
TGM2	0.029028
C1orf226	0.028932
FABP5	0.028850
KIAA1467	0.028770
MBOAT1	0.028751
C6orf141	0.028732
CCDC86	0.028697
HCK	0.028663
DDIT4	-0.028657
IFITM10	0.028643
RIT1	-0.028596
TMPRSS2	-0.028556
TIAM1	0.028497
ADRB1	0.028399
RRP9	0.028101
CHEK2	0.028086
LHX4	0.028070
KIAA0513	-0.028026
RPP40	0.028000
KRT15	0.027965
RPRM	-0.027942
TPD52L1	0.027926
DMRTA1	-0.027855
SYBU	0.027849
DRAM1	-0.027807
BYSL	0.027615
S1PR3	-0.027613
ABCC5	-0.027409
TMEM120B	0.027323
GABARAPL1	-0.027315
LYAR	0.027305
KCNF1	0.027209
PUS1	0.027132
RRP12	0.027112
GPATCH4	0.027059
RLN2	0.026955
TMEM45B	-0.026949
CELSR2	0.026882
CDC25A	0.026871
ARHGEF37	-0.026861
FAM174B	-0.026832
ZNF485	0.026773
PMAIP1	0.026736
TFF1	0.026734
ELOVL2	0.026730
NOL6	0.026727
NOC3L	0.026700
MANEAL	0.026692
KHK	0.026647
TRERF1	-0.026561
PNRC1	-0.026462
NUAK1	-0.026414
PNRC1	-0.026392
TAF4B	0.026375
MYO3A	0.026364
MPPED2	0.026311
SLC37A3	0.026298
SLC22A5	0.026100
RARA	0.026023
CCDC82	-0.025837
FKBP4	0.025827
FAM57A	0.025780
MTFP1	0.025737
WDR3	0.025607
MXD4	-0.025595
CHST8	0.025542
CCNG2	-0.025509
DPH2	0.025500
UTP20	0.025477
WDR12	0.025413
TCF7L1	-0.025411
CARD10	0.025396
NBPF22P	0.025379
C10orf10	-0.025364
KIAA0020	0.025328
TIPIN	0.025287
TMEM201	0.025268
ABCC5	-0.025214
NTN4	-0.025213
WDR74	0.025188
CDKL1	0.025183
TCP11L2	-0.025175
TGFB3	-0.025094
SOX3	0.025083
LIMA1	-0.025080
RDX	-0.025052
TNS3	-0.025009
LMO7	-0.025004
TRERF1	-0.025000
RNF144B	-0.024993
TPD52L1	0.024975
MYBBP1A	0.024941
ADCY3	0.024880
KLHL24	-0.024810
POLR1B	0.024770
CITED4	0.024724
MTHFD1L	0.024650
FAM84A	-0.024646
ERBB2	-0.024624
SLC9A3R1	0.024520
MLKL	0.024485
IFIT1	-0.024476
RPF2	0.024452
PIGW	0.024388
C10orf2	0.024375
CDH26	0.024313
PPRC1	0.024291
ST8SIA4	-0.024282
KCNJ3	-0.024258
COL12A1	0.024171
NKAIN1	0.024155
FKBP4	0.024118
PTGES	0.024109
CDC42EP2	0.024083
BEND3	0.023915
PCOLCE2	0.023905
UCK2	0.023900
SRSF7	0.023885
PPARGC1B	0.023843
FLNB	0.023840
AEN	0.023792
FAM171B	-0.023754
BOP1	0.023736
TFF2	0.023691
CCDC88C	0.023663
RIBC2	0.023572
MCM10	0.023521
SYT12	0.023498
LOC400768	0.023491
CDKL5	-0.023484
MYO1B	-0.023476
RARG	-0.023451
DOK7	0.023426
MYO1B	-0.023390
PPARGC1B	0.023352
TMTC2	-0.023351
MTHFD1L	0.023333
KALRN	0.023330
DKC1	0.023310
SLC16A6	0.023201
RRP15	0.023196
SPRY1	-0.023194
HEY1	-0.023193
DHODH	0.023147
CYP1A1	-0.023046
ZNF239	0.023016
SLC24A3	0.022990
DDX10	0.022936
PYCRL	0.022906
GEMIN4	0.022818
TRIM14	0.022775
TRMT1	0.022740
AMPD2	0.022720
MAP6D1	0.022696
NOP2	0.022692
SRSF7	0.022677
EXOSC2	0.022672
URB2	0.022665
PPA2	-0.022657
LRFN1	0.022624
KDM2B	0.022596
SLC19A1	0.022587
FBXO32	-0.022544
PNPT1	0.022530
PDCD2L	0.022512
SLC25A24	0.022504
RAB30	0.022500
ABCE1	0.022482
ALKBH2	0.022470
B3GNT5	-0.022452
EFNA1	-0.022445
WDR3	0.022434
TSPAN12	-0.022433
ADAT2	0.022433
DBP	-0.022422
SLC7A1	0.022402
RAI14	0.022394
NR2C2AP	0.022338
YPEL3	-0.022334
C1orf95	-0.022333
ATP11A	0.022239
MLLT10	-0.022223
ELF3	-0.022218
SEH1L	0.022212
FAM171B	-0.022207
RASD1	-0.022174
NDRG1	-0.022145
MMS22L	0.022144
ANK3	-0.022131
SPIRE2	-0.022128
TSEN2	0.022116
ZNRF3	0.022113
CCNG2	-0.022086
KDR	-0.022077
TNRC18	-0.022076
TMEM150C	-0.022070
BIK	-0.021954
PALM3	-0.021916
ACAA2	-0.021904
UHRF1	0.021888
COBLL1	-0.021808
MOCOS	0.021763
MAGEA6	0.021746
ANK3	-0.021673
ANKH	0.021672
NDUFAF4	0.021619
CDKL1	0.021608
HR	0.021554
TMEM164	0.021545
FAM84A	-0.021403
CDYL2	-0.021389
FUT4	0.021365
NOP56	0.021363
CD3EAP	0.021351
LYZL1	0.021338
PUS7	0.021327
PIK3R3	-0.021318
SLCO4A1	0.021314
ABHD2	0.021301
ARID5B	-0.021268
SLC29A1	0.021248
STAU2	-0.021232
UHRF1	0.021220
AMD1	0.021193
RUVBL1	0.021168
ETV6	-0.021093
TTC27	0.021059
POLR3H	0.021057
BRIX1	0.021032
AMIGO2	-0.021013
DHX37	0.020994
MARCKS	-0.020958
AEN	0.020949
KLF12	-0.020941
CHDH	0.020895
QSOX2	0.020885
FOXC1	0.020819
ATAD3A	0.020816
HBP1	-0.020800
TRMT61A	0.020792
DHX33	0.020769
PAK1IP1	0.020748
RAMP3	0.020732
ST8SIA6	0.020726
PLK2	-0.020696
TIPARP	0.020651
SYTL2	-0.020639
F12	0.020637
RRP1	0.020630
GAB2	0.020628
SEMA5A	-0.020627
SRSF1	0.020576
GADD45B	0.020554
PLEKHH2	-0.020520
CTU2	0.020486
E2F2	0.020475
MREG	0.020468
EXOSC2	0.020449
IGDCC3	-0.020422
MYADM	-0.020416
SIK1	-0.020401
FAM83B	-0.020359
TARP	-0.020341
BAHCC1	-0.020339
SHH	0.020321
WDR81	0.020318
MPZL2	-0.020308
SLC26A2	0.020303
FAM110C	-0.020292
ST3GAL1	-0.020288
MRTO4	0.020284
PDSS1	0.020283
CAB39	-0.020279
DCAF13	0.020275
ZNF703	0.020264
AKAP1	0.020259
AKAP1	0.020238
NLE1	0.020225
CLIP1	-0.020224
GINS3	0.020219
RRP15	0.020201
HEATR1	0.020127
RCL1	0.020111
CD244	0.020099
POLR3G	0.020096
TIMM8A	0.020074
RNF207	-0.020060
PPP1R3C	-0.020059
FBXL18	-0.020009
LNX1	-0.019974
PRSS23	0.019945
UTP18	0.019942
HES1	-0.019931
OVOL2	0.019901
MXD4	-0.019898
SCFD2	0.019887
PDSS1	0.019887
NLE1	0.019825
SLC2A8	0.019802
STON1-GTF2A1L	-0.019792
WDR46	0.019786
PALM3	-0.019760
CHEK2	0.019756
MRM1	0.019752
LHFPL2	-0.019741
NOTCH3	-0.019713
BASP1	-0.019697
ABHD4	-0.019696
CCNG2	-0.019691
TBC1D21	-0.019649
HPDL	0.019628
CDT1	0.019601
PCDH9	-0.019580
MON1A	0.019565
B3GALT4	-0.019501
STK32C	0.019495
IGFBP3	-0.019471
NOLC1	0.019467
HEG1	0.019452
ZNF367	0.019433
EPB41L4A	-0.019418
NXT1	0.019397
RCL1	0.019352
NAT10	0.019346
DSCC1	0.019343
ALDH1B1	0.019314
ORC1	0.019259
POLR1A	0.019257
FBXL17	-0.019254
C1orf226	0.019240
PP14571	-0.019239
CAST	-0.019224
ARHGAP20	-0.019201
SLC47A1	0.019169
LGALS8	-0.019168
NUDCD1	0.019164
CCDC120	-0.019160
SERPINB1	-0.019150
PSD3	-0.019134
RIOK1	0.019117
FAM161B	-0.019090
ANKH	0.019081
PDCD11	0.019070
TMPRSS6	-0.019032
PLD6	0.019016
TRIM14	0.018986
GREB1	0.018971
VEGFC	-0.018962
TMEM151B	-0.018909
MRVI1	-0.018909
RASSF2	-0.018845
CHD6	-0.018818
ATAD3B	0.018802
SYCN	-0.018799
PODXL	0.018796
RASEF	-0.018795
PCYOX1L	0.018758
ASB13	0.018747
AMOT	-0.018739
NUDT7	-0.018730
ATAD3C	0.018671
JAK2	0.018654
KAZN	0.018643
SACS	0.018625
PARP8	-0.018616
THNSL1	0.018581
ABCE1	0.018579
DCLRE1B	0.018572
BEGAIN	0.018571
NOP56	0.018553
ATAD3B	0.018537
IKZF2	-0.018513
ZNF552	0.018507
POC1B	0.018498
LYSMD2	0.018470
IL1R1	-0.018448
NUP35	0.018446
PRIM1	0.018444
TMEM164	0.018433
TOX2	0.018424
NOM1	0.018403
MICB	0.018394
NRIP1	0.018389
INPP4B	-0.018364
FARSA	0.018356
IRX2	0.018353
FRY	-0.018345
LOC729680	0.018342
QTRTD1	0.018329
UTP14A	0.018328
B3GNT3	0.018326
NCOA3	-0.018288
TMEM139	-0.018285