!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!ligand_name	estradiol
!ligand_id	CHEBI:23965
!cell_type	estrogen receptor (ER)-positive MCF7 breast cancer cells
!organism	human
!end_metadata
ID1	-0.195873
S100A7	0.171635
SLC7A5	0.159965
BCAS3	-0.126124
LXN	-0.113981
DKK1	-0.112934
NME1	0.103386
ASS1	0.102814
YBX1	0.097371
RPL26	-0.094770
ADIRF	-0.094747
PPT1	-0.094282
COX7A2	-0.092515
BAMBI	-0.086511
PSMA6	0.086273
GSTM3	-0.081676
COX6C	0.079768
GATA3	-0.079564
PTP4A1	0.077023
SERPINA3	0.075480
BASP1	-0.074963
TPD52L1	0.074919
IER3	-0.073863
FBP1	-0.072404
MAPK6	0.072056
PRDX1	0.070244
HSP90AA1	0.069922
FDFT1	0.069446
SNHG8	-0.068493
RPL39	-0.068378
TCN1	0.068257
CLU	-0.068137
HSPE1	0.067471
PTTG1	0.065786
MRPL36	0.064847
HSPA8	0.064716
TUBB	0.064293
TUBB4B	0.064186
LDHA	0.064149
SLC3A2	0.064075
ID2	-0.064068
IARS	0.063492
SLC9A3R1	0.062773
NPY1R	0.061548
CCT2	0.061540
TUBA1B	0.061519
NPTN	-0.061423
VAMP8	-0.061359
MRPL3	0.061041
NOP10	0.059363
CSTA	-0.059113
PSMB5	0.058827
RPS23	0.058612
ID3	-0.058450
CDIPT	-0.057598
SIAH2	0.057264
ARMCX6	0.057173
ARL6IP1	-0.056276
TXNIP	-0.056002
CERS2	-0.055897
ZNF217	-0.055515
CD24	-0.055434
TFF1	0.055258
CTSD	0.054937
ENO1	-0.054916
GLO1	0.054655
PLEKHF2	-0.054632
UBE2T	0.054052
IRF2BPL	-0.053828
HEBP1	-0.053694
SNRPD2	0.052624
TSPAN13	-0.052330
UBE2S	0.051575
MIF	0.050855
BTG1	-0.050534
ATP1B1	-0.050216
TUBA1A	0.050107
TUBB3	0.049874
RPS13	-0.049572
HSP90AB1	0.049507
S100A9	0.049426
RPS20	0.048792
MT2A	0.048753
PPIB	0.048501
C20orf24	0.047664
TRMT112	0.047652
TSTD1	-0.047606
ISG15	0.047240
PNRC1	-0.047093
DDIT4	-0.047067
REEP5	-0.046898
DYNLT3	0.046587
TMEM64	0.046531
TUBA1C	0.046380
CEBPB	0.045986
NHP2	0.045954
RAN	0.045741
S100A8	0.044877
BANF1	0.044705
UQCRFS1	0.044701
CYC1	0.044220
SLC25A5	0.044090
C6orf211	-0.043798
PSMA1	0.043725
SLC35A1	-0.043605
KPNA2	0.042730
DDX21	0.042538
PSMC1	0.042316
TUBB6	0.042281
CCT7	0.041979
LOC100129361	-0.041601
CMC2	0.041498
NPM1	0.041463
GPR160	-0.041393
ATP5B	0.041172
HSPB8	0.041126
EEF2	0.041029
KARS	0.040875
MYEOV2	0.040713
DYNLL1	0.040143
HIST1H2AC	-0.040006
EMG1	0.039933
HIF1A	0.039767
AHSA1	0.039240
UBE2C	0.038999
FBL	0.038763
CCT5	0.038755
G6PD	0.038597
ERH	-0.038546
TMEM106C	-0.038492
SLIRP	0.038309
BOLA3	0.038143
DNAJC1	-0.037909
VDAC2	0.037868
MB	-0.037811
PSMB3	0.037474
C12orf57	-0.037424
EIF4A1	0.037410
HILPDA	-0.037361
TMA7	-0.037287
SGCG	-0.037207
PSAP	-0.036971
ZFP36L2	-0.036751
PLK2	-0.036660
ITM2B	-0.036602
RPS25	-0.036533
S100A10	-0.036445
AMIGO2	0.036439
SLC38A2	0.036026
CDKN1B	-0.036008
NDUFAB1	0.035998
PKIB	0.035996
PABPC3	-0.035895
UCP2	-0.035873
PRMT1	0.035757
DSP	-0.035599
EGR3	0.035581
SYTL2	-0.035556
TMEM150C	-0.035340
HMGN3	-0.035270
ISOC1	-0.035127
MYO1B	-0.034888
C1QBP	0.034807
SNRPB	0.034731
OAZ1	0.034647
IRX3	-0.034645
RPS14P3	-0.034624
PSMD14	0.034559
MIR21	-0.034513
SEPP1	-0.034480
RPL24	-0.034448
SNRNP25	0.034364
SAT1	-0.034243
ATP5G3	0.034083
SNHG1	0.033975
PSMC3	0.033946
TKT	0.033921
PRELID1	0.033820
ZFAS1	-0.033671
ADIPOR2	-0.033668
BNIP3	0.033595
ANXA2P2	-0.033552
DHRS2	0.033492
CBWD1	0.033454
SYTL5	0.033438
FTL	0.033304
PTGES3	0.033249
CCT4	0.033074
CDK2AP1	0.032984
NMD3	-0.032943
CKS1B	0.032812
ETFA	-0.032800
RBL2	-0.032747
TOMM5	0.032745
EEF1A2	-0.032581
PTRH2	0.032548
ERP29	-0.032524
LAPTM4B	0.032436
NQO1	-0.032144
STIP1	0.032126
ANXA2	-0.032111
H1F0	-0.032072
PNPT1	0.032059
MRPL15	0.032023
RPL36	0.031996
HMCN1	-0.031857
MSMO1	0.031830
SEC61B	0.031814
DSTN	-0.031761
AARS	0.031754
DNAJA1	0.031462
GREB1	0.031454
RBBP7	0.031452
SH3YL1	-0.031425
ATP5G1	0.031072
RAB31	0.030945
USMG5	0.030602
PHB2	0.030590
LDOC1	-0.030584
MRPS23	0.030516
PRDX4	0.030312
SF3B6	0.030114
STUB1	0.030098
POMP	0.029979
UQCRH	0.029904
GABARAP	-0.029884
SEC61G	0.029845
FHL1	-0.029714
NDUFB11	-0.029693
PIK3R3	-0.029617
RPL41	0.029593
NOL11	0.029501
HSPH1	0.029482
DCTPP1	0.029440
RRM2	0.029393
SEC13	0.029334
PPIF	0.029325
FAM96B	0.029133
LINC00052	0.029122
XPOT	0.029038
ZDHHC7	-0.028766
TFRC	0.028697
SF3B5	0.028547
TPBG	0.028390
PSMD12	0.028364
SLC26A2	0.028327
RARS	0.028190
USP32P2	-0.028073
PAICS	0.028004
PKM	0.027967
LYSMD2	0.027843
RAB9A	-0.027731
ILF2	0.027704
PSMD2	0.027616
EFNA1	-0.027356
PHB	0.027322
GRB14	-0.027138
EIF4H	0.027019
GNG10	-0.026846
HSP90B1	0.026843
MTCH1	-0.026697
EPCAM	-0.026527
SMIM14	-0.026521
NUP107	0.026493
NOP58	0.026476
RPS4X	0.026463
CA12	0.026463
CXXC5	0.026353
PGAM1	0.026208
SNRPG	0.026184
SSR4	0.026111
F11R	-0.026011
PGR	0.025990
ABCE1	0.025954
TOB1	0.025926
POLR2G	0.025904
SNRPA1	0.025892
GLA	0.025882
HNRNPAB	0.025789
C6orf48	-0.025677
CELSR2	0.025672
COX1	0.025668
NDUFA1	0.025609
RPL34	-0.025456
TMEM30A	-0.025438
GLRX2	0.025398
PPM1K	0.025301
RPS12	-0.025246
FAM84B	-0.025152
BAG3	-0.025098
HAT1	0.025089
SCD	0.025005
PBK	0.024956
RPL17	0.024705
RPL6	-0.024679
TAGLN2	0.024580
STARD10	0.024544
COX7B	0.024534
MLPH	-0.024514
C14orf2	0.024494
GPI	0.024483
MRPS24	0.024409
EPB41L4A-AS1	-0.024376
NDUFA4	-0.024335
NELFCD	0.024333
PEG10	0.024288
RPL4	0.024243
MDH1	0.024239
GRN	-0.024184
CDKN3	0.024117
SOCS2	-0.024076
MRPL16	0.023999
TMEM59	-0.023907
GPRC5A	-0.023823
RAB25	-0.023799
TOP2B	-0.023638
RPLP1	-0.023588
MANF	0.023544
PMP22	-0.023494
RPN2	0.023457
FKBP4	0.023454
ANXA6	-0.023454
COX3	0.023438
HINT1	0.023314
PPP1R3C	-0.023278
RPS26	0.023219
GLB1	-0.023203
OSBPL9	-0.023197
TXN	0.023192
COX6B1	0.023189
SMIM15	0.023066
PSMD8	0.023047
SRSF2	0.023032
RUVBL1	0.022921
PTTG1IP	-0.022907
MRFAP1	-0.022858
NDUFA9	0.022829
SGK3	0.022728
YPEL5	-0.022626
MRPL18	0.022608
MAL2	-0.022551
KRT8	0.022503
ACTG1	0.022478
C17orf58	-0.022387
ATP5C1	0.022366
CCT3	0.022326
MYO6	-0.022265
EIF3D	0.022232
CD164	-0.022190
UBP1	-0.022176
DPM1	-0.022083
RPS7	0.022019
RNASEH2A	0.022015
NDUFS3	0.021988
PA2G4	0.021902
APPBP2	-0.021860
LASP1	-0.021843
RPL26L1	0.021834
SRM	0.021811
ARNT2	-0.021781
SLC12A2	-0.021779
HIST1H1C	-0.021736
RNF139	-0.021724
SEC11A	-0.021699
PUF60	0.021676
IFITM3	0.021629
CTSA	-0.021613
NPNT	-0.021599
H2AFJ	0.021580
TFAP2C	0.021569
ABHD17C	-0.021524
NDUFB3	0.021498
ZG16B	-0.021486
DHCR7	0.021472
AIMP2	0.021456
GDI2	0.021443
DPY30	0.021442
PPIA	0.021429
NAA20	0.021427
C19orf53	0.021295
RPL9	0.021268
DNAJA3	0.021257
AP3S1	0.021249
UQCRQ	0.021237
TMEM205	-0.021167
COMT	-0.021159
AURKA	0.021152
PDIA6	0.021089
PRKRIR	0.021045
PNP	0.021003
ZWILCH	0.020947
GOLPH3	-0.020773
CYCS	0.020741
CDH3	-0.020712
CCT8	0.020707
HIST1H2BK	-0.020669
C14orf119	0.020667
CCDC53	-0.020593
CREB3L4	-0.020539
DDR1	-0.020515
B4GALT1	0.020512
PSMB6	0.020490
B2M	-0.020458
SRP19	0.020454
WSB2	-0.020418
MRPL51	0.020357
EIF3K	0.020303
HNRNPA1	-0.020303
AGR2	-0.020287
KLHDC2	-0.020250
RPL23A	0.020245
COA4	0.020090
CIRH1A	0.020042
PARK7	0.020011
TM9SF2	-0.019991
SCP2	-0.019970
MANSC1	-0.019950
KIAA1191	-0.019890
SUMF2	-0.019863
TALDO1	0.019857
TCEAL3	-0.019843
TOMM20	-0.019835
EIF4A2	-0.019787
CCNG2	-0.019748
SUSD3	0.019741
ANK3	-0.019717
PTS	0.019711
PRMT5	0.019703
C14orf166	0.019700
ATIC	-0.019673
HSPA9	0.019666
PTPLA	-0.019656
IDI1	0.019592
PSMA7	0.019514
VPS28	-0.019463
DDX39A	0.019431
ALDOA	0.019329
CALB2	0.019323
RPL22L1	0.019282
NCOA4	-0.019221
NGRN	-0.019201
MT1X	0.019200
SNHG19	-0.019183
HIST1H3H	-0.019181
CAPNS1	-0.019158
DARS2	0.019112
LETMD1	-0.019101
DDX47	0.019093
EMC4	0.019068
NDUFB1	-0.019025
PRPF4	0.018984
PRDX6	0.018979
NME7	-0.018969
WRB	0.018956
MRPS2	0.018953
EIF2S1	0.018873
TACSTD2	-0.018837
WDR12	0.018787
PSME1	-0.018784
HDGF	0.018740
ARL6IP5	-0.018713
SNRPA	0.018640
PRDX5	-0.018640
IFIT1	0.018632
EBPL	0.018603
FTH1P5	-0.018596
PPA1	0.018501
JTB	0.018492
DRG1	0.018490
EEF1D	-0.018472
S100A11	-0.018462
NAE1	0.018415
DANCR	0.018372
NDUFA3	0.018361
ATP9A	-0.018359
HIST1H2BG	-0.018297
CDK4	-0.018290
PLBD1	-0.018285
SELENBP1	-0.018280
SYNGR2	-0.018200
HMGN1	-0.018189
HSPA5	0.018149
PRSS23	0.018120
HNRNPH3	0.018104
PSMB7	0.018030
TMBIM6	-0.018017
PIM3	-0.018006
HSPA4	0.017966
ADRM1	0.017961
TMED9	0.017938
UBE2M	0.017930
FAM96A	-0.017913
PTPLAD1	-0.017886
SNRPD3	0.017875
SUMO2	-0.017817
CDH1	-0.017774
CFAP20	0.017760
RAB11A	-0.017713
CRELD2	0.017620
MRPL14	0.017593