!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Rattus norvegicus
!drug_name	rosiglitazone
!smiles	CN(CCOC1=CC=C(C=C1)CC2C(=O)NC(=O)S2)C3=CC=CC=N3
!pubchem_cid	77999
!cell_type	Livers - 48 hours after exposure
!organism	rat
!end_metadata
IGFBP1	-0.120626
LCN2	0.114132
COX8A	-0.109640
SULT2A1	-0.107041
HMGCS1	0.106450
CHCHD10	-0.104692
FGA	0.104400
INSIG1	-0.104013
PCK1	-0.098212
MIF	-0.096095
APOA4	-0.094027
TUBB2A	-0.091524
CTSV	0.083475
COMT	0.079306
EPHX1	0.078451
TSC22D3	-0.078372
ZFP36L1	0.078308
RPL35	-0.077931
ALAS1	-0.077840
SCD	-0.077171
HPX	0.077145
XBP1	0.077136
ADH1C	-0.077093
UPB1	0.076992
A2M	0.076923
SOD1	-0.075625
DDT	-0.075227
CIDEB	-0.075058
ACADM	0.074772
ACLY	-0.074747
DCXR	-0.073035
TSKU	-0.072184
ATP5L	0.071792
ETFB	-0.071005
HAO2	0.070580
FABP7	0.070328
CFH	0.069563
SRD5A1	-0.069291
CEBPB	-0.069163
ACOX2	-0.068930
C3	-0.067826
IRF2BP2	-0.067574
CRP	0.067219
CYP1A2	-0.067099
DECR1	0.066145
C8G	-0.066096
HHEX	-0.064979
ERRFI1	-0.064468
MFSD2A	-0.063158
METTL7B	-0.062888
OAF	0.062367
SERPINF2	0.062335
VKORC1	-0.062315
KRT18	0.061956
POLR2L	-0.060978
AMACR	0.060701
KRT8	0.060447
ANGPTL3	0.059451
UBD	0.059416
C9	0.058919
SAT1	0.057786
ND3	0.057633
RPS28	-0.056782
HMGCS2	0.055966
FAM111A	0.055923
CFHR1	0.055850
ALDOB	-0.055800
AHSG	-0.055402
PHYH	0.055391
INSIG2	-0.055207
LCAT	-0.054867
GOT1	0.054569
ANG	-0.054329
TTR	-0.053158
TTPA	0.052920
COX6A1	-0.052818
CP	0.052314
FGG	0.051639
LDHA	-0.049525
ZNF354A	-0.049072
NDUFB7	-0.049003
ALDH3A2	-0.048999
ETFA	0.048952
COX1	0.048848
RPS23	-0.048517
HSD17B2	0.048329
RPL31	-0.048254
RNASE4	0.048216
ADTRP	-0.048150
AMBP	-0.048077
CHCHD2	-0.047813
NDUFB9	-0.047709
HAL	-0.047466
VTN	-0.047372
SDC4	-0.047190
TMEM176B	0.046920
GSTM5	0.046665
PIGR	0.046363
SRSF4	-0.046096
APOA1	0.045915
GCK	-0.045360
GJB1	0.045296
CYB5A	-0.045052
RPS12	-0.044770
EGR1	-0.044660
ASL	0.044511
RETSAT	0.044448
GLRX5	-0.044107
PPP1R3C	-0.043983
ACAT1	0.043918
RPS16	-0.043354
FAM210B	-0.043347
DDX5	0.043229
NDUFB6	-0.043053
KRTCAP2	-0.042942
HSD17B6	-0.042902
FBP1	-0.042743
NDUFA11	-0.042658
EFNA1	0.042516
ADRA1B	-0.042486
SAA2-SAA4	0.042427
G6PC	-0.042376
IDI1	0.042299
HES6	-0.042204
ATP5G1	-0.042181
MSMO1	0.041800
CSNK2B	-0.041674
ENPP2	0.041359
LAMP2	0.041330
CYP2E1	-0.041175
RPL19	-0.041066
SDS	0.041020
PNKD	-0.040654
HSPA5	0.040245
NDUFB5	-0.039550
FASN	-0.039309
RPL38	-0.039268
AVPR1A	-0.039198
CTSH	-0.039181
EIF4EBP3	0.039052
SERPIND1	0.038900
SUCLG2	0.038728
ZFP36	-0.038706
HERPUD1	-0.038561
NFE2L2	0.038533
LBP	0.038427
UQCR11	-0.038239
FAU	-0.038221
ACADSB	0.038193
SLC38A4	0.037754
BAAT	0.037660
EIF2S2	0.037578
HMGN1	0.037497
RPL10	-0.037496
EIF5A	0.037231
NCL	0.037142
CAPNS1	-0.037121
ARL1	0.037060
ACY1	-0.036939
APOC4	-0.036935
RPS9	-0.036925
HAAO	-0.036742
C5	0.036742
SLC2A2	0.036661
TTYH2	-0.036634
FETUB	-0.036564
GNMT	0.036470
ASPDH	-0.036452
NDUFB4	-0.036434
COX7B	0.036313
TMEM37	-0.036293
DBI	0.036097
HRSP12	0.035964
RPP21	-0.035911
ALDH1A1	0.035545
EPHX2	0.035430
SEC61G	0.035411
RPS15	-0.035362
UGT2B17	-0.035351
PPA1	-0.035241
SLC38A2	-0.035127
TMEM30A	0.035017
PPIA	-0.034985
DAK	-0.034964
DGAT2	-0.034746
FGL1	0.034627
LIPC	-0.034548
RPL8	-0.034501
CD14	-0.034382
MID1IP1	0.034142
KHK	-0.034105
ZFAND6	0.034066
NRBF2	-0.033763
TST	-0.033739
ERGIC3	-0.033644
APOA2	-0.033638
HMOX1	0.033582
CREG1	-0.033519
ATP5H	-0.033518
UQCRQ	-0.033503
TAF10	-0.033325
NDRG2	-0.033063
APCS	0.033024
BNIP3	0.032986
GSTK1	-0.032940
EDEM1	-0.032913
PBLD	0.032887
CLK1	0.032884
AHCY	-0.032864
NQO1	0.032775
ANGPTL4	-0.032535
SDCBP	0.032445
POLG2	-0.032184
GAMT	-0.032125
ALDH1L1	-0.032039
MGP	-0.032038
GUCD1	-0.031986
SLC25A22	-0.031813
RBP4	-0.031803
ALDH6A1	0.031773
ERLIN1	0.031756
MAP1LC3B	0.031755
UQCRC2	0.031735
PAQR9	-0.031660
PRDX1	0.031651
SV2B	0.031615
SPP2	-0.031424
SLC22A8	-0.031419
FAM120A	-0.031403
RPL27A	-0.031389
NDUFB11	-0.031378
ATP6V0C	-0.031353
SERINC1	0.031304
DHRS7	0.031287
ENO1	-0.031220
SLC13A4	-0.031206
PFN1	0.031086
DHCR24	-0.031069
NDUFB10	-0.030995
PPDPF	-0.030982
GLUL	0.030728
HGFAC	-0.030669
NDUFC2	-0.030604
CTBS	0.030589
OSGIN1	0.030558
ALDH9A1	-0.030556
TMEM53	-0.030520
SULT1E1	0.030309
SFR1	0.030088
IGFBP3	-0.029983
RPS27A	0.029931
HSPE1	-0.029856
RARRES2	0.029795
GC	-0.029759
PKLR	-0.029678
HNRNPH2	0.029629
TM4SF4	0.029257
NPM1	0.029244
APOM	-0.029146
CYP7A1	-0.028984
IGFALS	-0.028980
CDC42EP4	-0.028774
PARK7	-0.028534
HPD	-0.028261
MBD2	0.028224
SERF2	0.028142
TXN2	-0.027994
ITIH2	0.027990
SNX3	-0.027840
TARS	0.027685
ECHS1	0.027588
UBC	-0.027345
MAP2K2	-0.027288
CTSB	0.027225
CYTB	0.027197
ABHD14B	0.027165
CDKN1A	-0.027075
PGPEP1	-0.026947
TGFBI	-0.026902
YBX1	0.026885
ADHFE1	0.026837
HGD	-0.026689
ATP6V0D1	-0.026675
UQCRFS1	0.026663
JUND	-0.026626
HACL1	0.026540
ALDH2	-0.026539
ACSL1	-0.026491
SHMT2	0.026422
EIF4A2	0.026343
NIT2	0.026341
TIMM23	-0.026299
MDH1	-0.026284
LONP2	-0.026275
CYP51A1	0.026264
TAX1BP1	0.026190
TPT1	-0.026099
C1QBP	-0.026073
FGB	0.026044
CNDP2	-0.026001
NDUFA1	-0.025877
MCFD2	0.025855
DLD	0.025801
CD74	0.025773
H6PD	-0.025729
THRSP	0.025690
KLKB1	0.025675
TPST2	-0.025636
COL3A1	-0.025553
FMO5	0.025439
NAA38	-0.025376
ASS1	-0.025307
DPT	0.025280
GRHPR	-0.025271
UBE2D3	0.025255
HNRNPK	0.025236
NDUFV3	-0.025188
YIPF5	0.025183
ATP5G3	-0.025165
ATF4	0.025155
ALDH7A1	-0.025147
HINT2	-0.025099
RCAN1	-0.025051
PGRMC1	0.024970
CALR	0.024962
UQCRC1	0.024930
GINM1	0.024882
HAGH	-0.024762
MYC	-0.024717
ITIH4	-0.024716
SEPHS2	0.024665
FAH	-0.024583
GCHFR	-0.024535
CHMP5	0.024507
RPS15A	0.024486
CA8	0.024409
AARS	-0.024405
EHHADH	0.024322
BHMT2	0.024201
RPS2	-0.024114
HSD17B4	0.024106
FURIN	-0.024095
RPL36AL	-0.024077
SULT1B1	0.024002
GSTM2	-0.023999
PAICS	0.023973
PROS1	0.023956
COPE	-0.023944
DSTN	0.023936
TECR	-0.023901
NME2	-0.023846
RPS29	-0.023813
ACSL5	-0.023799
NR1H4	-0.023755
RABGAP1	0.023623
HAO1	-0.023540
SORD	-0.023463
ATF5	-0.023406
SLC41A2	-0.023368
B2M	0.023342
CSTB	0.023332
ALAD	-0.023324
FABP1	0.023284
DNAJB9	0.023215
UBA1	-0.023131
GHITM	0.023106
SLCO1B3	0.023096
UQCRB	-0.023047
COX16	0.022998
SLC22A1	-0.022964
DHTKD1	-0.022948
AGT	-0.022817
RPL17	-0.022793
TMEM248	-0.022766
MATR3	0.022759
TPCN1	-0.022706
HSP90AB1	-0.022681
GAPDH	-0.022592
IGFBP4	-0.022495
FXYD1	-0.022470
HSP90AA1	0.022420
GNL3	0.022413
SEZ6	-0.022303
SH3BGRL	0.022297
ARG1	0.022163
AOX1	-0.022126
EIF3M	0.022073
CLPTM1L	-0.022055
NDFIP2	0.022040
HNRNPU	0.022018
CPT1A	0.021981
RBM47	0.021978
SLC25A25	-0.021953
DHRS3	-0.021952
LAMTOR2	0.021924
DNAJA1	0.021821
RPS10	-0.021816
SPCS3	0.021598
CLU	0.021584
TTC36	-0.021537
FKBP4	-0.021503
CUL1	0.021494
BTG1	-0.021360
F9	0.021342
SLC17A2	0.021261
RPLP0	-0.021249
MORF4L2	0.021244
P4HB	-0.021243
ATOX1	-0.021172
CFL1	-0.021155
RPS14	0.021149
PPP1R3B	-0.021120
MKNK2	-0.021110
TPI1	0.021100
RAB18	0.021093
CXCL12	-0.021052
CUTA	-0.021037
RPS11	-0.021033
NAGS	-0.021025
MAFB	-0.020940
PCBD1	-0.020875
MUT	0.020859
RPL18A	-0.020848
PAH	0.020793
PGM2	-0.020692
HNRNPH1	0.020687
AGPAT2	-0.020681
PRDX4	0.020629
NET1	0.020578
TBRG1	0.020575
TDO2	0.020572
RNASEK	-0.020571
IDH1	0.020558
ACSL4	0.020450
PLA2G16	-0.020441
CDH17	-0.020414
ACADL	0.020390
SRA1	-0.020387
RPS8	-0.020367
NAT8	-0.020251
SEPP1	0.020202
SERP1	0.020184
HSP90B1	0.020151
C6	-0.020148
LAPTM4A	0.020140
CIDEC	-0.020137
CTDSP2	-0.020089
PSMB3	-0.020076
RBM39	0.020051
ACSM1	0.020048
ACO1	-0.020003
GSTA5	0.019999
ACADVL	0.019997
HEBP1	-0.019993
OSTC	0.019952
CMC1	-0.019855
UGP2	0.019814
AGXT2	0.019727
RPL6	-0.019719
RPS13	-0.019718
SLC26A1	-0.019697
AADAT	0.019658
AGMAT	-0.019609
RBM3	0.019609
RBBP7	0.019580
EMC2	0.019417
SURF4	-0.019391
RPL12	-0.019379
PEMT	-0.019335
GBE1	-0.019330
ANKS4B	0.019286
POLD4	0.019157
ECHDC2	0.019154
PAIP2	0.019135
FABP5	-0.019088
MOCS2	-0.019057
MPST	-0.019030
MRPL53	-0.019021
OAT	0.019004
EDF1	-0.018981
MTHFD1	-0.018980
PDK2	-0.018957
PLIN2	-0.018939
ASGR1	-0.018902
CD63	0.018892
STAC3	0.018835
BET1	0.018832
PAPSS2	0.018830
GCDH	0.018825
ETHE1	-0.018809
FN1	-0.018781
CREB3L3	-0.018765
PNRC1	-0.018756
LGALS8	0.018737
SSR2	0.018724
ADCK5	-0.018723
PRELID1	-0.018671
F11R	0.018660
SLC46A1	-0.018655
ACTB	-0.018621