!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!organism	Homo sapiens
!old	81-82
!young	72-79
!cell_type	CD4+Tlyphocytes
!age_unit	year
!organism	human
!end_metadata
GZMH	-0.109102
NKG7	-0.098059
FGFBP2	-0.091324
GNLY	-0.090904
GNLY	-0.090715
GPR56	-0.081345
GPR56	-0.079969
HLA-DRB5	-0.069480
GZMB	-0.065527
GSTM1	0.064874
S1PR5	-0.063823
GSTM2	0.063767
HLA-DRB1	0.063625
GZMA	-0.055670
NFS1	-0.055556
KLRG1	-0.054286
CCL5	-0.053721
PRF1	-0.052105
HLA-C	-0.052049
GSTM1	0.051371
HOPX	-0.049804
IL18RAP	-0.049235
CCL3L3	0.047867
DEFA1	-0.047271
CCL5	-0.046584
CCL3L1	0.045179
ERAP2	0.043815
CCL3L1	0.043651
CX3CR1	-0.043396
GSTM1	0.043304
PROK2	-0.043161
DEFA3	-0.042723
RPS4Y1	-0.041342
LGALS2	0.040443
NPSR1	-0.040277
CTSW	-0.039520
FCGBP	0.039255
PRSS23	-0.038945
DEFA1B	-0.038550
DEFA1B	-0.038238
CST7	-0.037553
HLA-A	0.036358
EOMES	-0.035973
SNHG5	0.035715
TARP	-0.035656
CCL3L1	0.035168
DEFA1B	-0.033849
CDK5R1	-0.033760
CMTM8	0.033486
CCL3	0.033421
LYAR	-0.033217
MATK	-0.033026
CD8A	-0.032700
AKR1C3	-0.032585
ADRB2	-0.032377
KRT1	0.031721
SLC15A4	-0.031298
ZNF683	-0.030976
LILRA3	0.030862
DDIT3	0.030666
COL18A1	-0.030488
AGAP1	-0.030378
GPR114	-0.030112
STOM	-0.029924
MFF	-0.029257
PRR5L	-0.029026
PLEKHG3	-0.028008
APOBEC3G	-0.027887
RPS26P11	0.027708
IER3	0.027615
GABARAPL1	0.027191
SLC7A5	0.027161
EIF1AY	-0.027006
PPP2R2B	-0.026964
CLIC3	-0.026327
ITGA4	-0.026208
MVB12B	-0.026090
CD163	0.025991
RPS4Y2	-0.025959
CENPK	-0.025952
CD8A	-0.025794
GBP1	-0.025720
JUP	0.025519
FOSB	0.025515
SCARNA9	0.025466
ITGAM	-0.025382
STOM	-0.025304
RPL9	0.025188
GNLY	-0.025004
DBH	0.024982
RPL36AL	0.024979
SNHG5	0.024899
GSTM3	0.024891
PLP2	0.024833
PRKCQ-AS1	0.024674
NINJ2	0.024647
AUTS2	-0.024628
SLC25A20	-0.024542
B4GALT5	-0.024539
RPL36AL	0.024458
KDM5D	-0.024355
TGFBR3	-0.024189
EFHD2	-0.023952
RNF113A	-0.023812
GALNT4	-0.023769
SYNE2	-0.023468
RNU11	0.023243
RNASE6	0.023238
GPR65	-0.023203
RPL38	0.023162
PTGDS	-0.023155
CITED2	-0.023096
PPP1R15A	0.023037
SLC2A3	0.022995
DPYSL4	0.022813
CCL4L1	-0.022794
HIST1H4C	0.022757
CXCL16	0.022590
GPR65	-0.022510
COX7C	0.022487
RPS29	0.022443
SOX13	-0.022418
ADAM7	-0.022374
CDKN1A	0.022355
SAMD3	-0.022314
RHOC	-0.022282
GBP5	-0.022276
MYC	-0.022266
SGK1	0.022201
LYAR	-0.022178
RPS26	0.022163
GFI1	-0.022156
RPL14	0.022133
TTC38	-0.022113
TCEAL2	-0.022044
ADA	-0.022037
SPATS2L	-0.021934
ZKSCAN2	-0.021882
TTC38	-0.021838
EPS15	-0.021756
PTGER2	-0.021732
VNN2	0.021709
RAP2A	-0.021707
SAMD3	-0.021702
SCGB3A1	-0.021653
RBM3	-0.021644
RAB22A	-0.021532
SH3TC1	0.021523
APOBEC3F	-0.021474
ATP5EP2	0.021419
CSNK1G2	-0.021384
PPFIBP2	-0.021368
PTGDR	-0.021353
TIAL1	-0.021340
HIST1H4A	0.021340
CLEC4D	0.021303
HIST2H2AA3	0.021275
CD163	0.021272
PELO	-0.021265
SAP30L	-0.021178
G0S2	0.021088
STAT1	-0.021055
ITGB1BP1	-0.021036
IFIT2	-0.021001
TMEM261	-0.020993
BTG2	0.020987
LRCH4	0.020972
RPPH1	0.020942
RPL17	0.020885
AFTPH	-0.020831
SMEK2	-0.020744
SLC15A4	-0.020736
MBP	-0.020730
ENC1	-0.020709
RPS29	0.020579
ASCL2	-0.020542
ZNF75D	0.020519
SP4	-0.020504
RPS9	0.020428
SIK1	0.020349
RSBN1L	-0.020289
PLAUR	0.020167
KCNT1	-0.020135
NDUFA1	0.020102
NMRK1	-0.020023
PADI4	0.019857
LINC00936	0.019829
SNX11	-0.019794
MATK	-0.019787
ING2	-0.019773
PRR5	-0.019759
RPL9	0.019734
FAM13A	0.019703
TOMM7	0.019688
CD14	0.019563
DYNLRB2	-0.019530
RPL30	0.019526
ATP5L	0.019516
PCF11	-0.019423
XYLT1	-0.019303
TIPRL	-0.019293
ATP5G2	0.019266
TRIM5	-0.019247
ANGPTL3	0.019172
HIST1H2BG	0.019165
NAPB	-0.019159
ATM	-0.019110
SC5D	0.019077
GBP4	-0.019059
RPS27	0.019031
ARID5B	-0.019030
FARSB	0.019015
GYG1	-0.019015
LOC729603	0.019006
KRT72	-0.018994
PIK3IP1	0.018987
SSBP4	-0.018978
LRRN3	-0.018957
S100A8	0.018953
IFNG	-0.018934
G3BP1	-0.018914
FNTA	-0.018902
WSB2	-0.018866
CDK5R1	-0.018788
HIST1H4B	0.018787
AVPI1	0.018738
CLDND2	-0.018702
CD3D	-0.018677
VEGFA	0.018671
ITIH5	0.018659
SLK	-0.018657
MBP	-0.018653
RPS27	0.018627
CD3E	-0.018625
DPY19L1	-0.018608
VAV3	0.018579
SAP30	-0.018575
HIST2H2AC	0.018566
TPST2	-0.018562
LAG3	-0.018559
ZNF486	0.018551
ZNF365	-0.018526
MIS18BP1	-0.018497
THEMIS	-0.018496
RPL32	0.018482
XIST	0.018468
CFD	0.018458
PLEK	-0.018452
RECQL	-0.018450
APOBEC3G	-0.018448
RPS6KA2	0.018440
CST3	0.018412
AIRE	0.018409
SLC2A14	0.018401
TAP2	-0.018389
LRP10	-0.018346
MYL6	0.018317
NEK7	-0.018312
DNAJC15	-0.018311
PIGA	-0.018254
RPL39	0.018161
RPL38	0.018155
RPL18	0.018149
COMMD8	-0.018148
LILRA5	0.018145
PROSER1	-0.018118
YWHAZ	-0.018105
NCALD	-0.018097
CRYZ	-0.018079
AKR1C2	0.018064
DLAT	-0.018061
SLC9B1	-0.018060
RORC	-0.018051
HIVEP3	-0.018047
F2R	0.018009
CTSB	0.017999
PI4K2B	-0.017985
ABCB1	-0.017975
GZMK	-0.017975
RPL35A	0.017966
PPP1R18	-0.017915
JUND	0.017876
TBK1	-0.017837
OSBPL5	-0.017834
FCGRT	0.017827
IGJ	-0.017803
IRS2	0.017788
ZFAND6	-0.017788
RPS9	0.017732
PTPN22	-0.017726
CD58	-0.017718
PAICS	-0.017708
BMI1	-0.017692
RPL11	0.017663
SERF2	0.017643
CHMP1B	0.017601
RPL27A	0.017601
CASP8	-0.017595
SMARCC2	-0.017584
GNG2	-0.017581
SP4	-0.017567
RPL18A	0.017564
TMSB4X	0.017538
NCALD	-0.017491
RPS25	0.017482
TRIM8	0.017473
APMAP	-0.017444
UCKL1	-0.017434
SCYL1	-0.017431
SOCS2	-0.017363
PTPN22	-0.017341
MXRA7	-0.017338
CBX4	-0.017330
GDPD5	-0.017314
RPL6	0.017311
RPA2	-0.017308
GOLGA6B	-0.017289
PRDM1	-0.017253
EEF1B2	0.017228
NIPSNAP1	-0.017220
SMAD5	-0.017216
ARL5A	-0.017172
RPL10A	0.017136
PRRC1	-0.017120
COX6C	0.017080
PSME3	-0.017041
LMO4	-0.017025
RPSA	0.017019
PLAUR	0.017015
TUBE1	-0.016996
TANK	-0.016990
NDFIP1	-0.016982
RPS24	0.016977
MRPL33	0.016940
CSRNP1	0.016938
HIST1H2BE	0.016904
CD1C	0.016873
BCL2L1	-0.016873
ICA1	-0.016866
RNASE2	0.016852
SYTL2	-0.016826
RAB11FIP5	-0.016813
METTL21B	-0.016804
GPR183	0.016800
S100P	0.016782
TGFBR2	0.016771
KLRD1	-0.016757
MMP23B	-0.016755
PRKAR1A	0.016754
CDK6	-0.016750
CBL	-0.016745
IL32	-0.016738
HPS3	-0.016724
ACTN4	-0.016722
FHIT	0.016667
C12orf29	-0.016665
COG6	-0.016638
SLC39A8	-0.016632
PFDN5	0.016628
LILRA3	0.016627
ABCA2	-0.016604
CHP1	-0.016604
SEC11C	-0.016584
RNF19B	-0.016580
HDGFRP3	-0.016577
SNRPD2	0.016575
DGKQ	-0.016567
STK40	-0.016560
VCL	-0.016537
VPS4B	-0.016535
GABPB2	0.016524
MDGA1	-0.016522
RBM34	-0.016503
DCK	-0.016481
EEF1A1	0.016479
BOLA2	0.016451
MGST2	0.016439
GSTT1	0.016439
TRIB1	0.016437
LXN	-0.016431
CSGALNACT1	-0.016420
TPST2	-0.016419
SFXN1	-0.016359
CLUAP1	-0.016354
CPEB2	-0.016345
KCNK10	-0.016331
JUN	0.016331
ABCB1	-0.016325
PDE4C	0.016323
ETV3	0.016313
RASSF1	-0.016307
ATP1B1	-0.016271
ATXN1	-0.016236
VHL	-0.016231
RPS14	0.016227
LPIN1	-0.016210
FGFR1OP2	-0.016203
NGFR	0.016193
CDA	0.016185
ERLEC1	-0.016185
YME1L1	-0.016181
UBE3C	-0.016172
TFG	-0.016163
PURA	-0.016147
ISG15	-0.016146
GPR183	0.016141
RPL21	0.016138
RPL41	0.016114
MCM8	0.016103
SUB1	-0.016089
GJC1	0.016086
NDUFS5	0.016084
SLIRP	0.016080
GPKOW	-0.016048
LPIN2	-0.016038
GNB2L1	0.016028
TMA7	0.016026
TIMM10	-0.016025
AXIN1	-0.016025
TMEM200A	-0.016017
GPX1	0.016011
FLI1	-0.015989
SOCS2	-0.015987
RPS29	0.015960
MAP3K8	-0.015950
C15orf48	0.015946
ZBTB11	-0.015927
DR1	-0.015923
RPS4X	0.015921
STXBP3	-0.015914
RCN2	-0.015903
FAM20B	-0.015900
HN1	-0.015900
SPAST	-0.015896
ZEB2	-0.015887
FYN	-0.015882
TMEM258	0.015879
CD14	0.015878
CTBP1	-0.015875
CDK4	-0.015865
NDUFAF6	-0.015863
IL17RB	0.015860
RPL6	0.015836
WIPF1	-0.015826
RPL18A	0.015823
RPL27	0.015805
ANPEP	0.015801
LILRB1	0.015797
ASB7	-0.015790
MYL6	0.015789
MORN3	-0.015780
CSF3R	0.015778
GBP1	-0.015758
MARCO	0.015743
OSBPL7	-0.015727
ACAP2	-0.015720
CASD1	-0.015701
STAT1	-0.015695
GNPDA2	-0.015691
ADAM10	-0.015686
LAIR1	0.015673
GOLT1B	-0.015673
GABPA	-0.015665
G3BP2	-0.015663
ATP1B1	-0.015655
GRASP	0.015654
IFNAR1	-0.015654
ING5	0.015653
RPL18A	0.015650
PLAUR	0.015643
VCPIP1	-0.015638
CES1	-0.015620
C1GALT1	-0.015594
TOMM7	0.015592
CAPRIN1	-0.015584
KIF21B	-0.015577
KIAA1468	-0.015559
FTH1P3	0.015551
OSBPL5	-0.015551
MKKS	-0.015548
DUSP1	0.015546
ADHFE1	-0.015541
GTDC1	-0.015541
RPLP2	0.015536
IL2RG	-0.015525
RAB10	-0.015516
RAB29	-0.015510
KIF21A	-0.015490
DDX60	-0.015487
CTSG	-0.015480
ATP2B4	-0.015480
TMEM107	0.015455
SEPT11	-0.015411
ARL5A	-0.015411
LILRB3	0.015406
BIRC2	0.015402
SNX5	-0.015393
PRKCB	-0.015391
STAMBPL1	-0.015378
MBIP	-0.015376