!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!drug_name	EPZ004777
!smiles	CC(C)N(CCCNC(=O)NC1=CC=C(C=C1)C(C)(C)C)CC2C(C(C(O2)N3C=CC4=C3N=CN=C4N)O)O
!pubchem_cid	56962336
!cell_type	MV4 -11 leukemia cell line - Day 4
!organism	human
!end_metadata
CFD	0.241397
CTSG	0.185570
LYZ	0.163597
LDHA	-0.134991
BEX1	0.120054
HLA-DRB1	0.113229
ELANE	0.110839
RPL36A	0.105725
SNRPG	-0.101006
HLA-DRA	0.087924
MSN	-0.085662
RPS8	0.085038
PRTN3	0.084735
RPS25	0.079398
ACTB	-0.078992
FTH1	-0.078326
SNHG5	0.077957
PGAM1	-0.077414
MFSD1	0.076916
RPS4Y1	0.076172
CEBPB	-0.075954
EEF1B2	0.075806
INSIG1	-0.075556
ERP29	0.075256
PPIB	-0.075103
RPL30	0.074714
AZU1	0.073865
MIF	-0.071524
PDLIM1	0.071185
IER2	-0.071079
GARS	-0.070850
NCOA4	0.069690
EIF3E	0.069603
SLC25A6	0.069475
RPS13	0.069262
ALDOA	-0.068889
SNHG6	0.068769
RPL9	0.067882
ZFAS1	0.066946
S100A4	0.066904
MAN2B1	0.066410
DDIT4	-0.066126
PLAC8	0.066031
LAMP5	0.064806
CLIC1	-0.064546
RPL12	0.063662
RPL11	0.063264
HLA-B	0.063039
IDI1	-0.062897
LGALS1	-0.061392
ATF4	-0.061376
SNHG8	0.061315
TYROBP	0.061171
LAPTM5	0.060792
HSPB1	-0.060474
CST3	0.060465
RPL24	0.060418
CHSY1	-0.059911
GPI	-0.059634
CCL5	-0.059187
HERPUD1	-0.058615
DDX39A	-0.057343
HSPA5	-0.056888
VIM	0.056828
LMNB1	-0.056816
RPL19	0.056736
PTPN6	-0.056488
RPS4X	0.056240
RRM2	-0.055579
PTMA	-0.055374
HSP90AA1	-0.054958
MS4A3	0.054856
NOP10	-0.054025
SLIRP	-0.053865
EIF3H	0.053524
TUBA1C	-0.052998
GBE1	-0.052361
FTH1P5	-0.052272
MSMO1	-0.052247
TFRC	-0.052140
QARS	0.051715
IRX3	0.051063
ISG15	-0.050572
IGF1	0.050363
TARP	-0.050026
ITGAL	-0.050021
RPS14P3	0.049847
UBE2S	-0.049616
EEF2	0.049525
LMO2	-0.049203
ITM2C	0.049188
GLTSCR2	0.048399
RPL15	0.048231
SLC7A5	-0.048226
RPL29	0.047832
SLC38A2	-0.047639
PFDN5	0.047548
HLA-C	0.047174
RPS5	0.047097
SEC61G	-0.046906
GNB2L1	0.046460
TXNIP	0.046264
APEX1	0.046172
SRP14	0.046007
EMB	-0.045779
FDFT1	-0.045744
RPS7	0.045712
OAZ1	-0.045346
RPL32	0.044683
CD74	0.044567
HSPA8	-0.044545
UBL5	-0.044544
PSME2	-0.044374
SERPINF1	0.044342
PFN1	-0.044110
RNASE2	0.044106
CDC42EP3	-0.044066
FDPS	-0.043939
ATP5J	-0.043567
GPR160	0.043452
HLA-A	0.043316
GOLGA8H	-0.043299
RPL22L1	0.043123
RPS27	0.043079
CCT8	-0.043046
ENPP2	0.042997
UGCG	-0.042971
GAPDH	-0.042960
RPL6	0.042682
TUBA1B	-0.042272
COX1	-0.042173
FAU	0.042009
RPL26	0.041942
RPL34	0.041931
MS4A6A	0.041185
ENO1	-0.041139
EIF3L	0.041040
NDUFB9	-0.040997
FADS1	-0.040835
ADA	0.040806
VAMP8	0.040637
RPSA	0.040618
OPN3	0.040381
NDUFB5	0.039833
RPL7A	0.039758
AARS	-0.039544
B2M	0.039540
PPIA	-0.039388
NAP1L1	0.038746
EMP3	-0.038693
NSA2	0.038487
RAN	-0.038316
FGL2	0.038149
UBC	-0.038128
RPL4	0.037912
RPL31	0.037726
RPL22	0.037120
EPB41L4A-AS1	0.036930
FCGR1B	-0.036856
NACA	0.036851
ACSL1	-0.036662
CES1	0.036632
ATF5	-0.036629
RPL10A	0.036626
RPL14	0.036541
JUND	-0.036453
HSPE1	-0.036412
NME1	-0.036350
TMEM14C	0.036184
EIF1	-0.035969
FAM46A	0.035958
H2AFZ	-0.035952
CD37	0.035897
DHCR24	-0.035302
RPL5	0.035215
CBWD1	-0.035146
HLA-DPA1	0.034928
PSAT1	-0.034876
TIMP1	0.034614
IARS	-0.034288
PPT1	0.034168
CXCR4	0.034023
RPS20	0.033812
RPS29	0.033521
RPL36	0.033515
YBX1	-0.033452
EIF3K	0.033322
SH3BGRL	0.033308
EIF3G	0.033230
LONP1	-0.033155
SCD	-0.033123
C6orf48	0.033024
XPOT	-0.033022
FLT3	-0.032982
CLEC11A	0.032954
BASP1	0.032905
PGK1	-0.032747
UFC1	0.032529
SAMHD1	0.032491
PABPC4	0.032327
GABARAP	0.032289
FTL	-0.032159
TUBB6	-0.031801
SNRPD2	-0.031779
RPL17	0.031753
ARHGEF18	0.031731
GRN	0.031677
EIF4A2	0.031617
CDC123	-0.031608
PPA1	0.031454
RPL36AL	-0.031447
ALOX12	-0.031330
ARPC3	0.031250
RPS27L	-0.031178
CHCHD2	-0.031163
CCNG1	0.031137
CAP1	-0.031086
WARS	-0.031009
MYO1G	0.030991
USMG5	-0.030977
COMMD6	0.030958
MXI1	-0.030941
RPS11	0.030930
CD302	0.030905
IMPDH2	0.030878
CSTA	0.030816
C12orf57	0.030671
SRGN	-0.030504
LAPTM4A	0.030445
ACAT2	-0.029844
HINT1	0.029819
CAT	0.029816
ZBTB33	0.029587
C14orf166	0.029503
RILPL2	-0.029439
CD97	-0.029431
LBR	-0.029386
UBA52	0.029294
EEF1D	0.029281
EIF4EBP1	-0.029076
SNHG19	0.029066
EEF1G	0.028792
IFITM2	0.028648
RPS12	0.028530
PSAP	0.028134
GAS5	0.027962
PCNA	-0.027782
RPL35	0.027618
DTX4	0.027552
CLNS1A	0.027536
PTRHD1	0.027535
ATP5G2	0.027252
GSTP1	0.027234
BNIP3	-0.026967
NDUFA12	0.026872
EIF2S3	0.026836
LCP1	-0.026734
HADHB	0.026680
AIF1	0.026600
GLO1	-0.026589
OXA1L	0.026568
LY86	0.026348
UQCRC1	-0.026330
TSPO	0.026294
MANF	-0.026147
TUBB4B	-0.026108
NDRG1	-0.025992
PYGL	-0.025956
MT1E	0.025833
HMGCR	-0.025771
POMP	-0.025768
MT2A	0.025759
SPCS1	0.025743
HPCAL1	-0.025650
PLP2	-0.025605
CDK2AP2	-0.025527
ACLY	-0.025459
BTF3	0.025449
RPS26	0.025388
LST1	-0.025376
RPL28	0.025096
TOMM20	0.025090
DNAJB11	-0.024900
RPS21	0.024877
CACNA2D3	0.024736
RPS6	0.024689
TMEM230	0.024681
NOP58	-0.024610
RPL21	0.024531
SELK	-0.024505
PEBP1	0.024491
TPT1	0.024349
RPN1	-0.024335
SLC39A4	-0.024307
EGR1	-0.024266
TRIB3	-0.024258
SQLE	-0.024125
SRSF9	-0.024081
TPI1	-0.024054
RPL7	0.024005
TMEM258	-0.023994
RPS24	0.023877
TBL2	-0.023868
BIK	0.023838
RPL37	0.023831
RPLP2	0.023750
VASP	-0.023721
HLA-DMA	0.023535
EXOSC8	-0.023520
ALAS1	-0.023517
RPL23	0.023397
ARL6IP5	0.023293
ITM2B	0.023256
SURF4	-0.023145
MCM7	-0.023121
RPN2	-0.023110
MTDH	-0.023022
VRK1	-0.023002
GABARAPL2	0.022996
RPL3	0.022983
MCM2	-0.022845
CDK5RAP3	0.022808
CSDE1	0.022771
ITGB2	-0.022762
EIF3D	0.022752
PRDX5	-0.022742
COTL1	0.022738
RPS16	0.022690
LAP3	-0.022670
RNASET2	0.022620
RPS17	0.022600
EIF3F	0.022556
SUSD1	-0.022335
RPA3	-0.022296
MT1F	0.022294
RPL27	0.022291
ALYREF	-0.022281
RPS2	0.022245
FABP5	-0.022223
ATP5L	0.022176
PSMD8	-0.022115
CCR2	0.022089
HSPD1	-0.022082
PAG1	-0.021953
RAB27A	-0.021919
UHRF1	-0.021893
ATP5G3	-0.021866
CDCA7L	-0.021699
FBL	0.021676
KYNU	0.021516
ARHGEF6	0.021491
ERH	-0.021483
RNASEH2A	-0.021460
AHCY	0.021434
KCNN2	-0.021419
RPL8	0.021410
CAPG	-0.021358
MIR155HG	-0.021315
EVI2B	0.021305
RNASEK	0.021226
ND2	0.021217
PRC1	-0.021198
DUT	-0.021176
NREP	0.021128
MRFAP1	0.021108
HMGN2	-0.021105
TMEM97	-0.021090
HSD17B11	0.021041
CEBPA	0.021006
H3F3B	-0.020986
PSMB1	-0.020939
RPS15A	0.020897
FEN1	-0.020893
HMGCS1	-0.020857
UQCRC2	0.020772
TCEB1	-0.020750
CCND3	-0.020617
HEXB	0.020530
HMMR	-0.020523
XBP1	-0.020516
LINC00493	0.020513
DPYSL2	-0.020508
NCF1C	-0.020349
TAGLN2	-0.020318
C19orf10	-0.020216
RPS9	0.020180
VPS51	0.020165
PPP1CC	0.020086
PSMB4	0.020080
LPCAT1	-0.020028
F13A1	0.020000
EBPL	0.019962
SDF2L1	-0.019920
TGFBI	0.019863
TIMM10	-0.019861
SRP9	0.019779
NCKAP1L	0.019772
NDUFS3	0.019733
ARCN1	-0.019732
UBE2T	-0.019620
STAR	0.019611
FAM101B	-0.019576
PPP1R27	-0.019394
GMFG	-0.019386
DAD1	-0.019355
AKR7A2	0.019339
RSRP1	0.019334
IFI6	-0.019279
RPL18	0.019157
PDIA6	-0.019122
BIN2	-0.019111
COMMD8	0.019108
MCUR1	-0.019057
HLA-DPB1	0.018977
HAT1	-0.018965
GNG5	-0.018964
HNRNPA2B1	-0.018906
CDIPT	0.018875
SLC35E2B	0.018872
CCT7	-0.018866
PTBP1	-0.018855
CYP51A1	-0.018832
ZFR	-0.018816
FASN	-0.018713
ARF4	-0.018637
PKM	-0.018627
VDAC1	-0.018597
LRRC75A-AS1	0.018594
HCLS1	0.018587
PAICS	-0.018573
SLC20A1	-0.018512
TRPM4	0.018480
PRELID1	-0.018464
ACAA1	0.018404
SRRT	-0.018370
SLC2A5	-0.018350
CRELD2	-0.018326
MARS	-0.018305
UBE2C	-0.018270
VKORC1	0.018263
AP2M1	0.018244
COX7C	0.018230
TMBIM4	0.018140
EBP	-0.018129
PTTG1IP	-0.018102
WDR83OS	0.018098
ESYT2	-0.018098
HNRNPA0	0.018094
ZWINT	-0.017993
C20orf24	-0.017986
BUB1B	-0.017976
UQCRB	0.017968
RPL13	0.017931
YARS	-0.017922
NDUFB11	0.017916
IL17RA	-0.017880
SLC3A2	-0.017851
GOLPH3	-0.017836
PTDSS1	0.017803
TNFSF13B	0.017752
EID1	0.017746
UXT	0.017702
TUBA4A	-0.017686
GINS1	-0.017578
HLA-E	0.017557
TARS	-0.017555
SMC4	-0.017550
SATB1	-0.017543
CCNB1IP1	0.017532
LSM4	-0.017529
CMPK2	-0.017500
UBE2M	-0.017499
TGFBR1	-0.017443
CUTA	0.017403
CHCHD10	-0.017359
HYOU1	-0.017355
EIF2S2	-0.017329
COPG1	-0.017281
AP1S2	-0.017265
MRPL51	-0.017175
HAUS4	0.017162
LPXN	0.017147
IL4I1	-0.017147
CECR5	-0.017130
LY75	0.017088
MCEMP1	-0.017087
ALDOC	-0.017064
TGM5	0.017037
RAB8A	0.016994
MAPK6	-0.016990
PSMA4	-0.016978
BUB3	0.016934
LDHB	-0.016878
BLVRB	0.016828
NCL	-0.016783
PLEK	-0.016713
RPS18	0.016696
BCAP31	-0.016626
UBA2	-0.016620
DBI	-0.016600