!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Rattus norvegicus
!ligand_name	Interleukin 1β
!ligand_id	3553
!cell_type	insulinoma cell line (Pdx1 overexpression)
!organism	rat
!end_metadata
CXCL2	0.494879
CXCL3	0.297285
SEMA4A	0.188873
SOD2	0.177635
NFKBIA	0.168796
NFKB2	0.142893
PDZK1IP1	0.142698
ALCAM	0.119815
SNRPD3	0.093505
CCND2	-0.087908
STAP2	0.071639
PSMA6	0.071399
UBD	0.067235
F11R	0.065274
S100A5	0.064465
SLC25A4	0.062041
IRF1	0.061934
SDC4	0.060362
RIPK2	0.058426
ARG1	0.056266
CSRP2	-0.055593
HSPA5	0.055525
NFKB1	0.055435
LTB	0.053504
MAPKAPK2	0.053462
GLRX3	0.053193
NKX2-2	-0.053032
PRPH	-0.052475
GAPDH	-0.052069
DYNLL1	-0.051894
RPS13	-0.050706
SLC37A1	0.050564
GBP2	0.050546
COX2	-0.050305
QDPR	-0.050269
PIM2	0.050154
LRRC42	0.049951
RPL7A	-0.049399
HSP90B1	-0.049362
APP	-0.048810
SYNJ1	0.048725
CHCHD10	-0.048654
UBA2	0.047483
B2M	0.047475
RPL35	-0.047394
STX7	0.046974
CHGA	-0.046752
FTL	-0.046501
RRAS2	0.046488
ACTB	-0.046475
UGDH	0.046409
TXNIP	-0.045314
GDE1	-0.045011
RNF115	0.044352
OXR1	-0.043872
GADD45A	0.043840
MAPT	-0.043465
TNIP1	0.043299
AMBP	-0.043182
RPL15	-0.042687
RPL13A	0.042634
RELT	0.042341
H2AFZ	0.041734
SPINT1	0.041625
MIF	-0.041565
EXOC6	0.041484
S100A10	0.041182
MICALL2	0.041087
ARPC5	0.041077
TMEM206	0.040751
BACE2	0.040501
NFKBIZ	0.040491
RPL8	-0.040310
ASNS	-0.040269
ALDOB	-0.040136
CNBP	0.040108
PPIA	-0.039920
RCL1	0.039913
HNRNPH1	0.039795
RPS2	-0.039330
CD164	-0.039111
UBL3	-0.038152
RAPGEF5	0.038117
BSG	-0.038038
CD63	-0.038011
TXNRD1	0.037940
MVP	0.037312
ALDOA	-0.037138
COX7B	-0.036991
FOXA2	-0.036951
EZR	0.036950
LGALS3BP	0.036485
DZIP1L	0.036071
PSMB9	0.035814
RPS15	-0.035742
CXCL16	0.035485
RESP18	-0.035468
HADH	-0.035205
ODC1	0.035091
HMGB2	0.034987
SLC2A2	0.034882
HN1L	0.034841
RPL27A	-0.034788
ATP5B	-0.034745
RPS17	-0.034296
RPL9	-0.034247
VDAC1	0.033707
AP1S2	-0.033564
RBM3	0.033556
BTG1	0.033349
ZNF706	-0.033345
MAPK6	0.033336
KRT8	-0.033308
LRP4	0.033196
PRNP	-0.033179
OPN3	-0.033079
TACC2	0.032944
RPS6KA6	0.032837
SLC39A1	0.032801
ACSL4	0.032751
PSME2	0.032620
CLIC1	0.032612
NCL	0.032569
CXCL10	0.032539
CHUK	0.032526
ENO1	-0.032213
BIRC3	0.032158
IGFBP3	0.032084
RPS15A	-0.031770
TMEM130	-0.031565
IAPP	0.031423
PBX3	-0.031271
TM4SF4	-0.031260
ACO2	-0.031145
ATP5G3	-0.031005
CSTF2T	0.030941
ND2	-0.030690
LRP11	0.030425
ENTPD3	-0.030349
NACA	-0.029966
RPL19	-0.029420
RPS21	-0.029330
PCBD1	-0.029320
PREPL	-0.029021
CCL20	0.028924
MAPRE1	-0.028824
RPL31	-0.028784
SLC25A5	-0.028597
HSPA8	-0.028591
ETNK1	-0.028519
CGRRF1	0.028473
ZC3H12A	0.028344
EEF1E1	0.028209
RPS19	-0.028023
SPTAN1	-0.027771
FOXJ3	-0.027679
PNMAL2	-0.027625
APH1A	0.027550
SEZ6	0.027272
RAB5A	0.027076
PPP4R2	0.027065
COX1	-0.027058
TM2D1	-0.026954
LMBRD1	0.026802
JAK2	0.026691
CST6	-0.026688
MSMO1	-0.026605
TMEM173	0.026507
TMEM56	0.026499
UBE2E3	0.026487
FAM98A	0.026462
RCAN2	-0.026368
STARD10	-0.026338
RPL18A	-0.026313
INSIG1	-0.026198
ERP29	-0.026190
TMEM252	0.026070
COX8A	-0.026013
GRAMD3	0.025940
RPLP0	-0.025908
KIT	-0.025905
CKS2	0.025830
MRPL18	-0.025761
GNAS	-0.025728
CCNI	-0.025635
TMEM109	-0.025611
PPP2R2B	-0.025555
HSP90AB1	-0.025497
SNX11	0.025493
IL13RA1	0.025371
ATP5J	-0.025362
RPS14	-0.025261
CABLES2	0.025167
LSR	0.025105
FAM115C	0.025100
GARS	-0.025083
TPI1	-0.024963
NSG1	-0.024895
FTH1	0.024876
STAT3	0.024781
SPINT2	0.024650
NDUFA4	-0.024552
BNIP3	-0.024549
UBE2H	0.024527
MCM6	-0.024374
UQCRHL	-0.024337
GLUD1	-0.024239
TRIM2	-0.024214
YBX1	-0.024125
FAS	0.024108
GSPT1	0.024063
UBE2QL1	-0.024029
MTCH1	-0.023977
SNCB	-0.023932
G0S2	-0.023922
RPS4Y1	-0.023921
VKORC1	-0.023917
PRDX1	-0.023906
SUN2	0.023877
ND1	-0.023852
TMED2	-0.023667
WRNIP1	0.023604
EIF1AY	0.023560
MID1IP1	-0.023499
SMIM3	0.023433
RPS27A	-0.023347
MTFR1	0.023327
HNRNPU	-0.023174
RBM47	0.023158
RNF14	0.023049
OXCT1	-0.022955
IFI44L	0.022877
PSMA5	0.022862
RPL5	-0.022853
G3BP1	0.022823
FRMD8	0.022817
NFKBIE	0.022735
PAK4	0.022733
ACTG1	-0.022723
EXT2	-0.022709
VWA5B2	-0.022643
RPL10A	-0.022603
PDCD10	0.022574
MKI67	0.022464
SNRPD2	-0.022435
NKX6-1	-0.022420
CCNH	0.022396
RPL6	-0.022343
NDUFV3	-0.022273
ATP11A	0.022222
KPNA4	0.022183
NUCB2	-0.022159
NDUFB6	-0.022142
NDUFB9	-0.022031
MRPL22	0.022013
RPS23	-0.021902
IRS2	-0.021885
HOPX	-0.021874
SND1	0.021847
LDB1	-0.021831
FBL	0.021806
TRIM35	-0.021789
PARP14	0.021771
LASP1	0.021725
IGF1R	0.021616
NPY	-0.021601
SWI5	0.021567
PCBP2	-0.021560
PSMB4	0.021410
RTN3	-0.021390
GSTO1	-0.021384
GNB2	-0.021303
ETV1	-0.021296
NDUFB4	-0.021284
ISG20	0.021281
ATP8B1	0.021149
SEC24D	-0.021029
NT5E	0.020965
TRAFD1	0.020964
NDUFA12	-0.020906
RPS9	-0.020845
CASP4	0.020825
CYTB	-0.020804
PSAP	0.020788
OAZ1	-0.020766
FAM89B	0.020667
ROMO1	-0.020648
CYP51A1	-0.020636
DTX3L	0.020588
CACYBP	0.020518
BTG3	-0.020420
YWHAH	0.020388
RASSF6	0.020385
TES	0.020382
RPS10	-0.020359
RPS5	-0.020356
CSNK2B	-0.020341
CST3	-0.020315
PRKCSH	-0.020315
FAM120A	-0.020289
LITAF	0.020222
SAT1	0.020157
NUP210	0.020120
PLCXD3	-0.020119
KDELR1	0.020104
CTSF	-0.020080
TBCA	-0.020073
SLC11A2	0.020064
HSPE1	-0.020057
SMPD3	0.020018
PMVK	-0.019995
TOMM6	-0.019911
BCL10	0.019904
RPL11	-0.019847
CCT4	0.019790
IDH2	-0.019733
SCG5	-0.019718
ATP6V1F	-0.019691
NDUFC2	-0.019523
WBP5	-0.019472
TMEM258	-0.019435
MCL1	0.019350
CHMP2A	0.019228
EGR1	-0.019210
SUGT1	0.019195
PTBP3	0.019193
TOMM7	-0.019160
PCNA	-0.019136
RPS28	-0.019051
NPDC1	0.019041
TMEM27	-0.019027
CIB1	0.018990
PARP8	0.018915
RPA3	-0.018854
ENC1	0.018849
PPP1R1A	-0.018800
SETD8	-0.018762
CEBPG	0.018608
ATP1A1	-0.018600
HSP90AA1	-0.018497
TMBIM6	-0.018494
VLDLR	-0.018394
NAP1L5	-0.018381
ACSL5	0.018257
AKAP7	-0.018233
GLUL	0.018214
RPL18	-0.018153
HS2ST1	0.018125
RPL26	-0.018111
NEUROD1	-0.018104
PARP1	0.018097
HSPA4	0.018097
TIAL1	0.018062
COX6A1	-0.018058
PSMD12	0.018010
GRB14	0.017959
EMC7	-0.017944
P4HA1	-0.017931
IFI30	0.017921
NR4A2	-0.017885
TNKS1BP1	0.017832
ATP6V1B2	-0.017813
LXN	0.017727
XBP1	0.017719
RIPK4	0.017691
NRP1	0.017677
PSMA7	0.017671
LRRN2	-0.017658
MAGED1	-0.017653
ERH	0.017641
MARK3	-0.017640
DHX9	0.017628
RPS26	-0.017611
DISP2	-0.017592
ZDHHC2	-0.017549
ARF4	0.017464
ATAD1	0.017463
DTX2	0.017436
LY6E	0.017379
FAM135A	-0.017376
GNG10	-0.017346
NDUFB2	-0.017308
SEP15	-0.017274
TSR1	0.017272
SEC61G	-0.017258
REEP3	-0.017251
RHOA	0.017232
TMCO3	-0.017213
FNDC3B	0.017164
TUBB	0.017151
COMT	-0.017137
PRLR	-0.017118
HNRNPA0	-0.017096
HEPACAM2	-0.017080
CDC42EP3	0.016993
PLAC8	0.016930
NNAT	-0.016888
ANXA11	0.016882
NMT1	0.016875
TXNDC15	-0.016814
PDAP1	-0.016812
NDRG1	-0.016788
MICU3	0.016785
SUOX	-0.016770
TMEM45A	-0.016767
RPS16	-0.016741
GOT1	-0.016720
CYB5A	0.016677
GHITM	0.016581
TMEM150C	0.016564
SEMA3C	0.016526
HDAC11	0.016506
GPC4	0.016494
HNRNPAB	0.016450
TMX1	-0.016431
KLHL7	-0.016351
ARRDC1	0.016349
RAB21	0.016331
PSME1	0.016280
DNAJC6	-0.016280
MFN2	0.016267
EIF2AK2	0.016170
RPL12	-0.016144
CPOX	0.016108
RAB3A	-0.016065
MED31	-0.016059
PRPF8	-0.016032
TJP3	0.016026
COPZ1	-0.016022
DDX39B	0.015981
HDAC2	-0.015951
ICAM1	0.015942
ARL3	-0.015886
CASR	-0.015704
LMAN2	-0.015692
RAB5C	0.015680
BEX4	-0.015653
ATP5C1	-0.015647
SSBP3	0.015629
PRKAR2B	-0.015613
RPN1	-0.015600
PPP2R1A	-0.015554
CHCHD2	-0.015552
RPS8	-0.015501
EEF2	-0.015491
SLC3A2	0.015421
KIAA1217	0.015407
GOLGA7	0.015398
FABP5	0.015390
NME3	-0.015385
G3BP2	0.015330
TRIM5	0.015320
TNKS2	0.015311
GPRASP1	-0.015303
MAPK3	0.015264
ATP5H	-0.015264
SEMA4B	0.015251
TRAF4	0.015199
B3GALNT1	0.015196
KPNA2	0.015136
PRKAR1A	-0.015127
PDCD5	-0.015126
AGA	-0.015114
NDUFC1	-0.015112
CDH1	0.015088
ATP5L	-0.015079
RPS20	-0.015076
APPL2	-0.015012
DCTN3	-0.014847
SNX4	0.014835
ADH5	-0.014824
PHTF2	-0.014763
COX7A2	-0.014752
SLC30A7	0.014741
CACNA2D1	-0.014738
CORO1C	-0.014732
TAX1BP1	-0.014720
ND3	-0.014717
TNPO1	0.014677
RPS3	-0.014675
DDIT3	0.014653
PDE3B	-0.014652
WDR6	-0.014648
NRSN1	-0.014645
SKA1	0.014621
MYCBP2	0.014586
DUT	-0.014583
NUP93	-0.014583
ATL2	-0.014578
PCSK2	0.014547
ATP6V0C	-0.014539
SNAP25	-0.014532
DCAF7	-0.014487
RBBP7	-0.014481
USP3	0.014431
RAN	0.014409
PPP1CA	-0.014405
IER3	0.014388
THTPA	0.014387
COX7A2L	-0.014330