!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!organism	Homo sapiens
!cell_type	MCF7cells
!pert_name	estrogen
!pert_id	CHEBI:50114
!organism	human
!pert_type	chemical
!end_metadata
RARA	0.076268
GREB1	0.070620
HEY2	0.070401
MYB	0.069660
PEX11A	0.063079
HSPB8	0.062947
IGFBP4	0.060290
MYC	0.059777
TSKU	0.058871
GPR68	0.058437
RAPGEFL1	0.054576
RASGRP1	0.054549
MYC	0.054493
CA12	0.053221
SLC22A5	0.050095
STC2	0.049568
CCDC88C	0.049015
SFXN2	0.048690
CASP7	0.047027
KCNK6	0.046944
RET	0.045619
TPD52L1	0.045324
NAV2	0.044200
ARID5B	-0.043708
MAP6D1	0.043149
KRT13	0.043029
CA12	0.042035
CASP7	0.041938
TPD52L1	0.041826
FAM102A	0.040280
PKIB	0.039036
FOXC1	0.038884
FAM102A	0.038465
DEPTOR	0.037886
IRX2	0.037825
PHLDA1	0.037119
NOP16	0.036139
GALNT4	0.035030
TP53INP1	-0.034633
SIAH2	0.034568
DDX10	0.034471
GINS3	0.034427
BMF	-0.034160
SLC9A3R1	0.034068
NOP16	0.033984
SIPA1L2	-0.033406
PGR	0.033335
P2RY2	0.032998
SLC7A5	0.032781
CCNG2	-0.032745
DEPTOR	0.032525
SLC25A24	0.032098
FJX1	0.031147
MICB	0.030596
BIRC3	0.030449
CYP1A2	-0.030269
NRIP1	0.030005
CCND1	0.029770
DKK1	0.029242
ALDH1A3	-0.029163
ST3GAL1	-0.028957
KITLG	-0.028761
TP53INP1	-0.028688
B3GALNT1	0.028428
FAIM3	0.028424
TLE1	-0.028275
SLC25A19	0.028265
ADCY9	0.028066
LAMA3	0.027661
ASCL2	0.027553
SOCS2	-0.027352
SNHG15	0.027104
SGK3	0.027023
ST3GAL1	-0.026939
MEGF9	-0.026877
ACKR3	-0.026874
B3GALNT1	0.026869
SALL4	-0.026751
RRS1	0.026737
FAM216A	0.026736
MARCKS	-0.026641
ALDH1A3	-0.026593
ABCC5	-0.026505
IL1R1	-0.026463
DOK7	0.026246
SOCS2	-0.026240
NCOR2	0.026230
ANKRD50	-0.026185
HECW2	-0.026171
ITPK1	0.025832
CXXC5	0.025825
SEC14L2	0.025715
THOC5	0.025642
ADAMTS9	0.025567
EPB41L5	-0.025564
CXXC5	0.025466
NAV2	0.025393
RCL1	0.025307
C10orf2	0.025293
PPFIBP2	-0.025288
SGK1	0.025202
ST8SIA4	-0.025188
FGD3	0.024972
KITLG	-0.024907
MSX2	-0.024903
A4GALT	0.024898
CLDN23	0.024819
WWC1	0.024765
KCNK6	0.024687
ECE2	0.024647
IPPK	0.024565
DAB2	-0.024525
NXT1	0.024413
PMAIP1	0.024296
SLC2A1	0.024264
SVIL	0.024192
SNHG15	0.024180
GRB14	-0.024153
KHNYN	-0.024082
BMF	-0.024060
RPS6KA2	0.023981
NIP7	0.023957
PPAT	0.023914
PAK1IP1	0.023902
NCOR2	0.023869
KIAA0020	0.023840
LYAR	0.023786
KLF10	0.023539
PUS1	0.023489
MBOAT1	0.023354
PDS5B	-0.023345
CARD10	0.023325
HIVEP1	-0.023301
AMD1	0.023244
ST8SIA4	-0.023195
SGK3	0.023168
SOX2	-0.023156
WDR4	0.023133
HCAR1	-0.023078
AP1S2	0.023027
MEIS2	-0.022958
HEY1	-0.022920
ACVR1	-0.022913
ASB13	0.022886
LYAR	0.022831
TNFRSF11B	-0.022772
BANP	0.022762
LRIG1	0.022755
DDX21	0.022748
B3GALNT1	0.022748
DAB2	-0.022713
MPPED2	0.022659
KIAA1211L	-0.022616
GCNT1	-0.022545
CXCL12	0.022443
PDCD2L	0.022362
POLR1C	0.022285
AP1B1	0.022233
CDKN2B	-0.022219
IL17RB	0.022149
SGK223	0.022144
GAB2	0.022135
EPT1	0.022124
PTGER4	-0.022078
PPRC1	0.022057
COA7	0.022030
NOP2	0.022000
KIAA1211L	-0.021991
NRP1	-0.021964
S1PR3	-0.021911
ARL4A	-0.021899
ABCA1	-0.021887
CA2	0.021857
ABAT	0.021839
SGK223	0.021746
BOP1	0.021695
PUS1	0.021597
SYT12	0.021516
RLN2	0.021456
ABCC5	-0.021430
LRIG1	0.021281
PFKFB3	0.021244
MESP1	0.021240
CISH	0.021231
TMEM30A	-0.021189
C1QTNF6	0.021157
TPD52L3	0.021124
SH3BP4	-0.021121
DKC1	0.021110
GADD45B	0.021100
C17orf96	0.021076
TNS3	-0.021029
BRIX1	0.021008
BYSL	0.021007
MAPT	0.020987
PERP	-0.020889
ATP1B1	-0.020872
AKAP1	0.020844
CBFA2T3	0.020826
AUNIP	0.020817
PLOD2	0.020809
IRF2BPL	-0.020763
RAB9A	-0.020727
BMPR1B	-0.020717
UNC45A	-0.020693
C3orf14	-0.020691
SYCP2	-0.020682
TRIM8	0.020680
FAM214A	-0.020631
FOS	0.020455
CXCL12	0.020409
TMEM2	0.020351
PUS7	0.020307
FKBP4	0.020291
PLEKHF2	-0.020278
COBLL1	-0.020239
RAB30	0.020234
CIPC	0.020202
NR5A2	0.020194
TRIM24	-0.020185
NOC3L	0.020180
TMEM156	-0.020148
NOP2	0.020133
GRHL3	-0.020129
C16orf74	0.020105
FAM102A	0.020086
STARD13	0.020061
PALB2	0.020030
CDKN2B	-0.019950
IRX5	-0.019907
PIK3R3	-0.019867
LTV1	0.019839
SHISA2	-0.019774
CAV1	0.019719
RIOK1	0.019692
SLC29A1	0.019692
SPACA7	0.019677
FAM83B	-0.019674
MCCC1	-0.019664
SNX24	0.019651
TFAP2A	-0.019640
RERG	0.019614
PDXP	0.019562
PLK2	-0.019532
PAK1IP1	0.019528
JARID2	0.019517
RBMS1	-0.019391
TIGD5	0.019389
MRTO4	0.019366
NOP56	0.019353
KLF4	0.019265
GEMIN4	0.019260
NDUFAF4	0.019235
BRIX1	0.019233
SNHG9	0.019221
RBM39	0.019182
MREG	0.019163
TFPI	-0.019154
GRAMD3	-0.019138
CA2	0.019133
FLNB	0.019132
KLHL5	-0.018968
MARS2	0.018966
ARHGAP12	-0.018947
GDF15	0.018940
FAM160B1	-0.018904
SNORA60	-0.018891
GPATCH4	0.018824
ATRIP	0.018803
AQP2	0.018759
ZNF239	0.018724
LYPD3	-0.018702
ST8SIA6	0.018631
BTG1	-0.018586
AMZ1	0.018583
NMUR2	-0.018534
RPP40	0.018515
VTCN1	-0.018510
THOC5	0.018495
TRIM47	0.018474
BRI3BP	0.018472
SHB	0.018449
CHAC1	0.018446
ADCY1	0.018437
NOTCH3	-0.018406
CTR9	0.018391
RNF144B	-0.018374
POC1B	0.018362
TGFBR2	-0.018352
TSR1	0.018329
PPAN	0.018307
RET	0.018305
TFF1	0.018277
CCNO	-0.018256
CDC25A	0.018179
POLR1C	0.018172
B3GALNT1	0.018127
PPM1K	0.018111
NOL8	0.018081
UGCG	0.018049
EPB41L5	-0.018045
TGIF2	0.017997
NXNL2	0.017940
HLA-DRB1	0.017926
SLC39A7	-0.017900
PNO1	0.017859
CDT1	0.017848
AEN	0.017827
PDE5A	-0.017821
SNTB2	-0.017814
ZMYND19	0.017783
MED13L	0.017782
DDX55	0.017776
PDE6A	0.017759
ORC6	0.017759
SLC29A1	0.017750
UCK2	0.017678
NUAK1	-0.017669
MTFP1	0.017604
CEMIP	-0.017602
URB2	0.017493
TTF2	0.017470
SYCP2	-0.017439
EPS15L1	0.017396
FRMD8	0.017392
GFOD1	0.017373
TSPAN9	-0.017349
CDC42SE1	-0.017340
PMP22	-0.017337
CREBBP	-0.017304
TGFA	0.017301
AEN	0.017296
WWP1	0.017285
MYOF	0.017277
VPS9D1-AS1	0.017253
MAK16	0.017239
CYP1A1	-0.017229
CCDC86	0.017216
WLS	-0.017214
SNAPC4	0.017156
NOLC1	0.017095
WDR46	0.017081
DPPA2	0.017073
SLC39A14	0.017060
TRMT61A	0.016977
PTGES	0.016975
DIP2B	-0.016917
LAMA3	0.016903
FZD2	-0.016896
WDR12	0.016891
METTL1	0.016879
FGFRL1	0.016877
XBP1	0.016850
PDGFB	0.016849
GINS2	0.016849
C15orf39	0.016848
ROCK2	-0.016810
ABAT	0.016776
GAD1	0.016766
MYBBP1A	0.016760
POLR3K	0.016740
PTMA	-0.016725
MPHOSPH10	0.016719
AHNAK	-0.016706
LCOR	-0.016693
KIAA0226L	0.016683
MAMLD1	0.016675
PNP	0.016672
GART	0.016621
C12orf29	0.016619
TACC1	-0.016615
KIAA1217	-0.016614
TGFB3	-0.016611
PLD6	0.016597
KNOP1	0.016594
KLF4	0.016544
CLDN9	-0.016542
QSOX2	0.016530
SOX3	0.016526
CYP26B1	0.016465
KAZN	0.016464
LYPD6B	-0.016456
KIAA0513	-0.016445
ZNF485	0.016414
ADAMDEC1	-0.016390
INTS8	-0.016386
TEX10	0.016379
PPAP2B	-0.016372
SLC20A1	0.016365
C1orf106	-0.016360
FLRT3	-0.016360
IQGAP1	-0.016318
ADM	0.016315
IZUMO4	0.016312
EGLN2	0.016303
MTFP1	0.016298
NBPF1	0.016279
PTPN13	-0.016275
GRPEL1	0.016222
SLC25A42	0.016217
CCNG2	-0.016185
GPATCH4	0.016180
BOD1	0.016160
ISG20L2	0.016157
GTF2IRD1	-0.016151
FAM86B1	0.016100
GEMIN6	0.016072
AHSA1	0.016068
HS3ST3A1	0.016064
EXOSC5	0.016043
BATF	0.016029
TPBG	0.016025
KCNF1	0.016010
TIFA	0.015976
CTSK	-0.015973
FLJ20021	-0.015963
CTPS1	0.015960
PDCD5	0.015956
FILIP1L	-0.015947
CD44	0.015942
PTPN14	-0.015938
QTRTD1	0.015936
RPRM	-0.015915
GRHL1	-0.015899
PIK3R1	0.015895
NT5C2	0.015893
SHROOM3	0.015893
NAV2	0.015881
FBXL18	-0.015875
ZNF618	-0.015848
COLEC12	0.015846
ZNHIT6	0.015827
ROR2	-0.015822
PRDM12	0.015819
ATF3	0.015785
PPARGC1B	0.015771
HEXA	-0.015734
IGSF11	0.015705
CCNE1	0.015641
CIRH1A	0.015610
CEBPZ	0.015609
RFTN1	-0.015606
PRKCH	-0.015601
SNORA6	0.015578
OGFOD1	0.015559
RBMS1	-0.015545
AXIN1	0.015542
GABRA2	0.015527
FAT1	-0.015501
SLC25A25	0.015469
CITED4	0.015452
MIR450A1	-0.015440
ENC1	-0.015437
TSEN2	0.015430
ERBB3	-0.015427
ASCC3	-0.015412
PRSS58	-0.015412
ALKBH2	0.015378
NEIL2	0.015360
C12orf65	0.015359
OR2A5	0.015353
IER5L	0.015332
MIR611	0.015304
ERN1	0.015296
GAD1	0.015291
PLEKHH2	-0.015234
SNHG17	0.015231
GEMIN5	0.015227
UBE2T	0.015217
IGFL3	0.015215
KCNK15	0.015212
CPEB2-AS1	-0.015196
DHX33	0.015186
NOL6	0.015176
OSMR	0.015158
PKIA	-0.015152
ATG14	-0.015139
PPP6R2	-0.015133
SEH1L	0.015111
TMEM217	-0.015106
SNRNP48	0.015099
TUFT1	-0.015083
PTPN13	-0.015076
CBX6	-0.015067
OTUD6B	0.015067
MGEA5	-0.015065
NR2F1	-0.015051
MAFF	0.015050
GRB14	-0.015031
RPL29	0.015013
ZNF205-AS1	-0.015009
UTP14A	0.015008
ARHGEF28	-0.014994
MYOF	0.014992
MIR221	-0.014990
NUAK1	-0.014986
MYADM	-0.014968
QTRTD1	0.014963
CITED2	-0.014946
MAD2L1	0.014939