!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Mus musculus
!ligand_name	Interleukin-6
!ligand_id	3569
!cell_type	macrophage (SOCS3 KO)
!organism	mouse
!end_metadata
CCL13	0.326224
PNP	0.187569
IL4R	0.183124
ZFP36	0.169042
FTH1	-0.135579
ZFAND5	0.134954
PTPN1	0.133018
WDR92	0.118820
LGALS3	-0.117595
IRF1	0.116374
KIAA0247	0.115544
IRGM	0.113150
ACTB	-0.113052
EMP1	0.111373
NDRG1	0.111353
GBP7	0.109972
S100A4	-0.109803
IFIT1B	0.106870
GBP2	0.104883
LITAF	0.104264
IFITM3	0.100241
PLIN2	-0.099485
LILRB4	0.099000
CTSD	-0.093582
PLP2	-0.093190
CH25H	0.087308
DAB2	0.086891
MPEG1	-0.085947
PLTP	-0.085421
AKR1A1	-0.081936
CXCL10	0.080756
CXCR4	-0.080730
UBC	-0.078448
GADD45G	0.075420
MYD88	0.075400
GBP4	0.073813
FCGR2B	0.073372
ISG15	0.072328
LAMP1	-0.068974
CD300C	-0.068821
TUBA1B	-0.068782
APOBEC1	-0.066877
PLK3	-0.065127
FCGR1A	0.064888
SGK1	-0.064256
DCK	0.064155
HIF1A	0.062575
LYZ	-0.062481
CD53	0.061296
ARPC3	-0.060699
BACH1	0.060657
BCL3	0.060255
CCL4	0.059426
ID2	0.058758
TGIF1	-0.058728
CHD4	-0.057717
RPS15A	-0.057501
SLC6A6	-0.056770
CD9	-0.056384
MYADM	0.056370
RPS2	-0.055981
CEBPA	-0.055979
SESN1	-0.055572
LDHA	0.055343
IFIT2	0.055191
SEMA4D	-0.054493
TUBA1C	-0.054338
HMOX1	-0.053991
FOLR2	-0.053454
CEBPB	0.051937
LIPA	-0.051756
RPL10	-0.051625
IER3	0.051363
CCR1	0.050223
GBP3	0.049878
PIM1	0.049753
PABPC1	0.049587
TXN	0.049434
CFL1	-0.048979
IRF8	0.048799
USP18	0.047938
RAC1	0.047937
ARHGDIB	-0.047834
CST3	-0.046476
TYROBP	-0.046098
STAT3	0.044924
NAMPT	0.044754
PSMB10	0.044587
ARF1	-0.043447
TRIM25	0.043301
IL1RN	0.043284
TSPO	0.043086
RPL19	-0.042980
ANXA2	-0.042659
LRP1	-0.042419
IL17RA	0.042369
LYL1	-0.041798
MCOLN2	0.041753
RPS5	0.041115
TRAFD1	0.040877
RPL37A	-0.040803
CASP1	0.040438
TXNRD1	0.039677
CEBPD	0.039613
RARS	0.039046
PLSCR1	0.038653
MYL12A	-0.038575
SEP15	-0.038163
RPLP0	-0.038067
PPIA	-0.037998
HLX	0.037190
VMP1	0.037114
BRI3	-0.037033
CCNB2	-0.036681
PGK1	0.036582
MDFIC	0.036536
BASP1	-0.036050
SQSTM1	-0.035893
LY6E	0.035882
CLIC4	0.035574
RPS26	-0.035423
RNF19B	0.035349
IFIT3	0.035339
TNFRSF1A	0.035278
ZFP36L2	-0.035189
ATP6V0C	0.035165
SDC4	0.035162
GNAI2	0.035077
CSF1R	-0.034600
TNFRSF1B	-0.034387
HK1	-0.034142
JUND	0.033961
DAXX	0.033913
SAMHD1	0.033850
LPL	-0.033257
ATP1A1	0.033084
CASP4	0.033083
MAN2B1	-0.032954
RPL18	0.032898
GSN	-0.032502
PRKCD	-0.032288
ITM2B	-0.032247
BTG1	0.032216
RPS7	0.032199
COX6A1	0.031887
PRDX1	-0.031673
SIRPA	-0.031515
SURF4	-0.031409
SNRPB	0.031084
RPS28	0.031027
PSMA2	0.030875
GRN	-0.030700
IFI16	0.030527
RABAC1	-0.030407
GM2A	-0.030382
FERMT3	-0.030372
ZNFX1	0.030211
ABCC3	-0.030122
CD68	-0.030066
SMPDL3A	-0.029910
DR1	0.029778
TPP1	-0.029621
ACTR3	0.029525
GNG5	-0.029312
HMHA1	-0.029264
S100A6	-0.029175
ADCY7	-0.029097
IRF5	-0.028712
MSRB1	-0.028508
SNX2	0.028259
CPT1A	-0.028190
S100A10	0.028104
RPS3	0.028085
C7orf43	0.027864
ID1	0.027863
CCRN4L	0.027792
KLF6	0.027451
PSMB8	0.027419
ITGAM	-0.027327
ARHGDIA	0.027030
RNF10	-0.026952
DHRS3	-0.026940
HNRNPM	0.026908
CBFB	0.026864
CD63	0.026756
SLC27A1	-0.026734
ANPEP	-0.026692
TRA2B	0.026674
CCL2	0.026633
ST3GAL5	-0.026540
SKAP2	0.026420
ADAM9	0.026296
TXNIP	-0.025905
PCYOX1	-0.025772
ANXA5	-0.025758
GNB2L1	-0.025743
RPL28	0.025696
ARFGAP2	-0.025656
TCIRG1	-0.025414
RPL3	-0.025328
C1QA	-0.025305
EVI2A	-0.025227
SLC2A1	0.025087
RNASEK	-0.024934
TLE3	0.024783
HCK	0.024751
ANXA1	-0.024725
CREG1	-0.024706
ESD	-0.024669
GRINA	0.024652
IL10RB	-0.024569
ANXA6	-0.024453
CD14	-0.024450
CTSB	-0.024414
SOCS1	0.024344
IFI35	0.024296
CKB	-0.024207
TPI1	0.023936
C1QC	-0.023780
STAB1	-0.023746
IDH1	-0.023636
TAP1	0.023599
TEC	0.023536
RNH1	0.023416
MXD4	-0.023208
EIF1AX	0.023162
UBE2S	0.022953
CD48	-0.022943
MAFB	0.022942
RGS14	-0.022843
MPP1	0.022819
FAM49B	0.022667
IGF2BP2	0.022555
CTSZ	-0.022503
PSTPIP1	0.022456
C5AR1	-0.022449
PMP22	-0.022387
RNF149	0.022284
CCNG2	-0.022110
GABARAP	-0.022076
ACTG1	0.021967
DAZAP2	-0.021871
LAPTM5	-0.021817
YWHAG	0.021655
RTN4	-0.021639
YPEL3	-0.021621
GAPDH	-0.021595
CCR2	-0.021570
CYBA	-0.021560
AP1S1	-0.021551
MAPK14	-0.021492
MORF4L2	0.021458
TUBA1A	-0.021385
CAPNS1	-0.021171
PSMA7	0.021156
PARK7	-0.021080
RAB5C	0.020960
CYTIP	0.020855
H2AFZ	0.020828
SPTLC2	0.020735
NCF1	-0.020711
GATM	0.020710
TMEM43	-0.020644
SPP1	-0.020615
DNASE1L1	-0.020613
CYB5A	-0.020590
RHOB	-0.020588
TGFBI	0.020582
TAGLN2	0.020549
ZNF281	0.020497
ITGB2	-0.020446
CLTC	-0.020435
MSN	0.020431
PNRC2	-0.020352
RELA	0.020269
FURIN	0.020096
UBA7	0.020077
RMDN3	0.019906
RGS2	-0.019894
EEF2	-0.019765
ATOX1	-0.019704
TPST1	0.019637
SDHB	-0.019635
KRTCAP2	0.019581
LCP1	-0.019558
STX12	0.019548
MKNK2	-0.019534
RSAD2	0.019490
GAS6	-0.019429
HN1	0.019356
CTSA	-0.019337
HNRNPH1	-0.019335
MIDN	0.019289
HERC1	-0.019251
RIN2	0.019182
KCNN4	-0.019093
TCF12	-0.019088
ATP6V0D1	-0.019033
ACTR2	0.019026
PPP1R15B	0.018998
BZW2	0.018969
DEGS1	-0.018850
JUNB	0.018796
CHMP4B	0.018765
JUN	0.018732
INPP5B	0.018709
SLC11A1	-0.018661
BLNK	-0.018485
CDC20	-0.018442
PSMD7	0.018435
SNX10	0.018361
NFE2L2	0.018252
PSMA6	0.018212
PDXK	-0.018203
EMR1	-0.018193
STK10	-0.018184
RTN3	-0.017975
PSMD8	-0.017852
ATP6V0E1	-0.017837
YWHAZ	-0.017807
CORO1A	-0.017797
UNC93B1	-0.017782
LARP1	0.017779
LGALS1	0.017770
PSMB9	0.017698
SMIM14	-0.017687
NPM1	-0.017667
PRDX3	-0.017642
RASA3	-0.017539
SLC31A1	0.017515
PPP1R21	-0.017509
NOP10	-0.017491
MARCH5	0.017489
TRAM1	-0.017472
PSME2	0.017461
GUSB	-0.017458
KDELR1	-0.017449
CCL3L3	0.017421
EPS8	0.017415
C6orf62	-0.017373
CRIP1	-0.017348
ACADM	-0.017318
ARL4C	-0.017297
NUPR1	0.017270
PLD3	-0.017241
BTG2	-0.017193
ARPC1B	-0.017177
LIMS1	0.017110
GORASP2	0.017100
FUCA1	-0.017041
RAC2	-0.016997
DCTN1	-0.016957
NSMCE1	0.016904
TRIM21	0.016886
PNRC1	-0.016780
CD72	-0.016727
MDM2	-0.016703
CDK18	-0.016608
SGTA	-0.016604
SPTSSA	-0.016524
SPATA13	0.016519
HSP90AA1	0.016469
ATP5A1	0.016461
SELT	-0.016451
PSMA3	0.016419
CSTB	-0.016359
OGFR	0.016321
ETNK1	0.016312
TAPBP	0.016308
UQCRC2	-0.016200
SUN2	-0.016063
RPS11	-0.016057
HNRNPA2B1	0.016051
CSF2RB	0.016031
RHOQ	0.016015
PTGER4	0.015922
IL10	0.015871
UQCRQ	0.015849
GPR50	-0.015745
C12orf57	-0.015731
CTSV	-0.015697
RAP1GDS1	0.015658
ICAM1	0.015653
LDLR	0.015651
TUBB6	0.015576
CAPG	-0.015556
RPL5	0.015536
ADAM15	-0.015525
EPN1	-0.015519
NCL	-0.015517
FAM96A	-0.015491
CDC42SE1	0.015489
TUBB3	-0.015488
GCH1	0.015450
NFIL3	0.015445
NDUFS3	-0.015374
ATP6V1B2	-0.015315
PML	0.015252
CAPZA2	0.015039
FOXO3	-0.014997
PTPRO	-0.014985
SLC12A7	0.014973
SERINC3	-0.014956
NCF4	-0.014838
STX4	0.014750
COX7A2	0.014733
SELP	0.014675
ANAPC5	-0.014666
GBA	-0.014656
B4GALT3	0.014628
PSMB6	0.014621
UBA1	-0.014594
KIF22	-0.014580
CCNDBP1	-0.014580
PAQR7	-0.014551
EIF2S3	0.014538
IFIH1	0.014526
TPT1	-0.014500
ADD1	-0.014463
NDUFV1	-0.014425
FLII	0.014397
SNX3	0.014396
INPP4A	-0.014391
VAV1	0.014367
CSDE1	0.014339
SOD1	0.014331
GPI	0.014324
TBL1XR1	-0.014318
MTCH2	0.014222
FLI1	-0.014210
PLEKHO1	-0.014204
SELPLG	-0.014139
EIF4A3	0.014135
B4GALT1	-0.014135
PLCG2	0.014113
FLCN	-0.014096
PPP4C	-0.014024
CYP4V2	-0.014005
APP	0.014002
TKT	-0.013941
COTL1	0.013913
TNFAIP8	-0.013893
BCL6	0.013892
RALBP1	-0.013873
TIPARP	0.013860
UGCG	0.013779
H6PD	-0.013735
YIPF4	-0.013684
GNA12	-0.013638
C15orf39	-0.013614
CLK1	-0.013603
TSC22D4	-0.013549
RGS10	-0.013519
SLC25A11	-0.013448
CFP	0.013429
IFI30	-0.013429
GTF2F1	0.013410
DDX39B	-0.013389
CDT1	-0.013355
GSTO1	-0.013316
CDC37	-0.013307
HSD17B10	0.013303
TOR1AIP2	0.013293
RNF5	-0.013225
NECAP1	-0.013222
LRRC59	0.013217
POLR2F	0.013205
PLEKHB2	-0.013136
NDE1	-0.013077
CSF2RA	-0.013076
BIRC5	0.013020
LGALS9B	0.012995
CCT4	0.012959
NACA	-0.012920
MAPK6	0.012912
NFKBIA	0.012860
RBMS1	0.012849
IL10RA	-0.012819
C14orf2	0.012718
MEF2A	-0.012679
FOS	-0.012638
RPL6	-0.012638
FADS1	-0.012595
SNX9	-0.012571
MYO1F	-0.012551
EIF3D	0.012543
HSPA8	0.012520
ATP1B3	0.012459
ENG	0.012449
LAMP2	0.012407
NSA2	-0.012377
ABCG1	-0.012366
RPL7	0.012360
RPL10A	-0.012327
MAF1	-0.012317
STK38	-0.012286
LRWD1	-0.012268
RBBP4	-0.012268
GNAS	0.012262
TRIM27	-0.012254