!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	BPDE
!smiles	C1=CC2=C3C(=C1)C=CC4=C3C(=CC5=C4C6C(O6)C(C5O)O)C=C2
!pubchem_cid	41322
!cell_type	WI-38  Lung fibroblasts - 0.5uM
!organism	human
!end_metadata
TUBA1C	-0.247736
LDHA	-0.208856
TUBA1B	-0.207257
TUBB	-0.163867
COL1A2	-0.148970
TUBA1A	-0.136993
GADD45A	0.133594
COX2	-0.128631
TUBB6	-0.121965
TUBB4B	-0.117690
SLC38A2	-0.114448
TMSB10	0.108703
LGALS1	0.104714
HSPA8	-0.102395
PMAIP1	0.101251
COX1	-0.101234
FTL	0.100622
RPL39	0.099850
RPS5	0.098611
COL1A1	-0.096112
TUBB3	-0.090392
SAT1	0.082425
MMP1	0.081672
SERPINB2	0.078497
NGFRAP1	0.077415
CFL1	0.073686
LAPTM4A	0.072831
SRP14	0.072753
KPNA2	-0.072421
PTGES3	-0.071423
COL3A1	-0.070569
HEXB	0.070409
PPIB	0.069122
RPL41	0.068141
H2AFZ	-0.066048
TIMP1	-0.065754
SGK1	0.065108
RPS19	0.063629
FTH1P5	0.062900
MEST	0.062410
EIF3E	-0.062120
USMG5	0.061789
GPX1	0.061703
IGFBP3	-0.060234
GREM1	-0.060124
CD63	0.057496
MTCH1	0.057414
RPSA	0.057267
RPL7A	-0.056525
HIST1H2BK	0.056183
TMA7	0.055561
MT2A	-0.054318
SERPINH1	-0.053720
RPL32	0.053405
ATP6	-0.053323
RPS15	0.053133
PARK7	0.053121
PTTG1IP	0.052956
RPS10	0.052941
RPL35	0.052374
MYL6	0.052198
ANP32B	-0.051187
NPTN	0.050554
C12orf75	0.050464
COL6A3	-0.049941
GARS	-0.049911
TMEM158	-0.049886
FN1	-0.049549
SLC25A5	-0.049194
ISCU	0.049084
B2M	0.049037
COTL1	0.048341
UBA52	0.047912
YBX1	0.047877
UBC	-0.047862
COX7A2	0.047756
RNASEK	0.047135
SNRPD2	0.046986
LOX	-0.046652
S100A4	0.046448
FAU	0.045589
RPL12	0.045447
UAP1	-0.045333
UQCRH	0.044856
NDUFA13	0.044767
CD59	0.044556
CD99	0.044523
IER2	0.044378
TAX1BP3	0.044327
SERINC1	0.043979
CTGF	-0.043382
MYL9	0.043240
SERF2	0.042654
PRDX4	0.042322
RPL23A	0.042161
CDK2AP1	0.042112
CDKN1A	0.041884
PEA15	0.041281
NDUFA4	0.041085
RPL30	0.040965
RPS18	0.040962
NPM1	-0.040770
ADM	-0.040745
CYR61	-0.040595
CKS2	-0.040239
EMP3	0.040148
ITM2B	0.040148
RPL9	0.039940
RPS11	0.039770
RND3	-0.039364
DCN	0.039080
MRFAP1	-0.039025
TGFBI	-0.038827
DAD1	0.038737
SNRPG	-0.038651
HINT1	0.038310
NEDD8	0.038251
RPLP0	0.038017
EEF2	-0.037352
RPL22	0.037278
RPS17	0.037259
HLA-A	0.037218
CTSB	0.037193
TM4SF1	0.037046
MRPL3	-0.036982
RPS21	0.036891
OAZ1	0.036732
RPS27	0.036539
RAN	-0.036517
EIF4A1	-0.036378
OST4	0.036309
COX8A	0.036275
HLA-C	0.035059
RPL29	0.034726
RPL8	0.034447
MAFF	0.034046
RPS7	-0.034041
ERH	-0.034020
BNIP3	-0.033753
ERRFI1	-0.033688
VIM	-0.033517
S100A13	0.033483
RPS20	0.033426
TIMP2	0.033360
EIF1	0.033061
STOM	0.032713
HSPB1	0.032518
RAP1B	-0.032438
RPL27	0.032395
ADAMTS1	-0.032349
RPLP1	0.032339
SPARC	0.032258
COX6B1	0.032189
RPS29	0.032055
MYL12B	0.032001
TCEB2	0.031981
PFDN5	0.031887
ARL6IP5	0.031687
TRAM1	0.031626
DYNLT3	0.031511
RPS12	0.031478
APEX1	-0.031333
GNG5	-0.031168
FTH1	0.031086
RCN1	0.030918
SEP15	0.030884
SPCS1	0.030808
CALM2	-0.030773
ATP6V0E1	0.030741
IARS	-0.030584
DDIT4	-0.030534
CCT2	-0.030381
ATP5L	0.030344
MAP1LC3B	0.030277
ACTG1	-0.030196
UBL5	0.030014
FOXD1	-0.030007
DSTN	0.029813
CLIC1	-0.029798
CD81	0.029746
HSBP1	0.029742
EIF2S2	-0.029740
COX6C	0.029623
NDUFA1	0.029621
CUTA	0.029611
ANLN	-0.029513
CSRP1	0.029507
CTSC	0.029399
WFDC1	0.029297
PTP4A2	-0.029194
GAPDH	0.029191
SNHG1	0.029167
TMBIM6	0.029164
FRMD6	-0.029132
H3F3B	-0.029127
PSAT1	-0.029115
SNHG8	0.029112
RPS26	0.029094
HMGN2	-0.029081
UQCRQ	0.028948
HSPD1	-0.028935
SSR4	0.028843
IGFBP7	0.028828
AK3	0.028749
SEC13	-0.028706
PPA1	-0.028633
SOD1	0.028617
GDI2	-0.028440
RPL36AL	-0.028287
C12orf57	0.028082
RPN2	0.027891
PTTG1	-0.027880
LAPTM4B	0.027721
UBB	0.027639
PSMB1	-0.027409
ATP5A1	-0.027340
ATP5J	0.027178
PSMD14	-0.027078
HSPE1	-0.027073
GSTO1	-0.027024
RPS2	0.026920
GNG10	0.026892
RPL17	-0.026831
CNN1	0.026747
SRPX	0.026721
SERPINE1	-0.026631
SERPINE2	0.026595
RABAC1	0.026530
EEF1G	0.026517
COX4I1	0.026497
NPC2	0.026444
FZD7	-0.026389
RPS25	0.026324
TMEM123	0.026216
LAMP1	0.026200
RPL21	0.026154
DKK3	0.025961
PRDX5	0.025927
ATP5C1	-0.025899
ATP6V0C	0.025848
GPX4	0.025755
RPL4	-0.025662
PPIA	0.025610
RGMB	-0.025605
TRIAP1	0.025572
PSAP	0.025512
C19orf10	0.025485
NDUFA11	0.025433
BDNF	-0.025416
SLC25A6	-0.025357
RPS3A	0.025317
POLR2L	0.025302
IFITM3	0.025178
NCOA4	0.024942
CCNB1	-0.024913
THY1	0.024899
ACTA2	0.024873
ITGAE	0.024831
MGST1	0.024786
TUBB2A	-0.024784
PRNP	0.024662
CLTC	-0.024593
RPL5	-0.024495
HSPA5	-0.024407
RPL28	0.024373
NSA2	-0.024246
EFEMP2	0.024246
GLIPR1	0.024213
PLAT	-0.024121
RPS9	0.024102
FBL	-0.024094
LDHB	-0.024021
MYL12A	0.024015
RCN2	0.024013
HERPUD1	-0.023845
RPL22L1	-0.023831
CAPNS1	0.023764
PRC1	-0.023709
TPX2	-0.023708
ND2	-0.023683
SERPINB7	0.023550
SH3BGRL3	0.023462
PITPNB	-0.023424
DCTN3	0.023373
GNG11	0.023268
HIGD1A	0.023210
ARPC1A	-0.023196
GLRX	-0.023116
H2BFS	0.023106
FST	-0.023053
TWSG1	0.023034
RASA1	-0.023023
CEMIP	-0.023005
NNMT	-0.022979
DBI	0.022817
EDIL3	0.022796
MFSD1	0.022785
IER5	0.022784
ATP6V1F	0.022768
GNB2L1	-0.022752
HMGB2	-0.022735
DDOST	0.022726
CD164	0.022705
TMEM59	0.022638
HMGB1	-0.022638
HSP90AA1	-0.022589
SNHG6	0.022522
IFITM2	0.022512
CHAC1	-0.022465
ENO1	-0.022442
TPT1	0.022422
RPL3	-0.022391
RPL11	0.022365
CLU	0.022342
WRB	0.022314
SKP1	0.022294
COL4A2	-0.022287
HLA-B	0.022239
NDUFS6	0.022231
TOB1	0.022217
ADI1	0.022134
MORF4L1	0.022104
RPS16	0.022095
RPL36A	-0.022071
DKK1	-0.022043
HSP90AB1	-0.021883
PRDX1	0.021843
CLDN11	0.021795
TSPO	0.021777
PSMB3	0.021692
ARPC3	-0.021684
PDCD10	-0.021574
AXL	0.021572
MT1HL1	-0.021513
GABARAPL2	0.021442
GPRC5A	0.021433
DYNLRB1	0.021420
ATRAID	0.021415
TNFRSF10D	0.021397
SDC4	0.021268
HNRNPK	-0.021234
CDC20	-0.021211
ATP5J2	0.021198
SH3BGRL	0.021196
LOXL1	-0.021156
PDIA6	0.021062
UBE2C	-0.021044
ATP5E	0.020989
PTMA	-0.020980
EEF1A1	-0.020910
FSTL1	0.020788
S100A10	0.020649
CHCHD2	0.020629
CYB5R3	0.020558
RPL36	0.020535
HIST1H2BD	0.020438
LPAR1	-0.020429
VEGFC	-0.020408
TAGLN	0.020389
RPS6	0.020387
MMP3	0.020334
COX7C	0.020282
RPL13	0.020261
S100A11	0.020144
VCAM1	-0.020123
RFK	0.020113
DHX15	-0.020094
GABARAP	0.020088
COX6A1	0.020064
TMEM230	0.019959
C14orf166	-0.019902
RRM2	-0.019822
HBEGF	0.019810
CDIPT	0.019793
PSMG2	-0.019723
TMEM14C	0.019654
UQCR11	0.019645
MAGED1	0.019498
S100A6	0.019403
UQCRFS1	-0.019285
CTSA	0.019183
SCP2	0.019147
TNC	-0.019047
GGH	0.019043
CKAP4	0.019026
SDCBP	0.019013
RPS24	0.018968
PRDX6	0.018900
ATP6V1G1	0.018895
ATP5B	0.018878
RNF11	0.018762
MYL6B	0.018690
VOPP1	0.018672
ATP6AP1	0.018620
ZMPSTE24	0.018543
ATF3	0.018486
IER3	0.018485
LRP11	0.018430
RPS3	-0.018421
EMC4	0.018364
SPPL2A	0.018336
MT1X	-0.018284
RPL37	0.018278
ATP6V0D1	0.018247
ACTG2	0.018078
ACTB	0.018059
ATP6V0B	0.018018
RPS13	0.017869
CCL2	-0.017809
PFN2	-0.017797
RTN4	0.017723
ECM1	0.017671
HNRNPA1	-0.017633
ZNHIT1	0.017606
VAT1	0.017591
MDH2	0.017584
CTSK	0.017547
CHMP5	0.017546
CD151	0.017533
NDUFB11	0.017518
SNHG19	0.017498
NACA	-0.017492
BCAP31	0.017475
SMURF2	-0.017452
LOXL2	-0.017439
UGCG	-0.017316
TMEM35	0.017275
TXNIP	-0.017253
GADD45B	0.017232
COX5B	0.017175
TMEM126A	-0.017156
PRSS23	0.017108
ATP6AP2	0.017080
PAM	0.017018
SARAF	0.017009
NEAT1	0.016996
SELM	0.016941
PGRMC1	0.016933
VKORC1	0.016868
PSMD2	0.016865
SNX3	0.016837
PCBP1	-0.016790
RPL24	0.016708
TIMP3	-0.016695
TMED2	0.016676
RPN1	0.016643
BDKRB1	-0.016611
PERP	0.016602
SCAMP3	0.016569
RAB1A	-0.016538
ASNS	-0.016482
ISG15	0.016475
KIAA1191	0.016457
SRP9	0.016449
AP1S2	0.016348
CAMK2N1	0.016298
MRPL36	-0.016285
GRN	0.016260
FAM96B	0.016198
PSMA6	-0.016161
RHOC	0.016149
TALDO1	0.016149
WLS	0.016144
SNRPB	-0.016123
RPL10A	0.016113
TMX1	0.016109
FOSL1	-0.016099
DAP	0.016088
MXRA7	0.016083
CETN2	0.016075
RBM24	0.016071
BRK1	0.016047
BUB3	-0.016018
SNRPD1	-0.015997
HIST1H1C	0.015982
SCOC	0.015932
TMCO1	0.015926
AKR1B1	0.015918
EIF4H	-0.015915
SNHG5	0.015912
SACS	-0.015906
FAM177A1	0.015887
ARMCX2	-0.015886
OPN3	0.015881
TAF7	0.015877
RPL13A	0.015860
CAV1	-0.015856
MRPL18	-0.015831
ARPC2	0.015814
CENPW	-0.015797
PGK1	-0.015746
ANXA4	0.015716
RPL26	0.015681
YWHAQ	-0.015676
PRDX2	0.015636
SRI	-0.015608
QSOX1	-0.015602
RARS	-0.015602
BCAT1	-0.015576
MELK	-0.015563