!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!ligand_name	17beta-estradiol
!ligand_id	CHEBI:16469
!cell_type	MCF-7 cells
!organism	human
!end_metadata
ARHGAP36	0.099215
PKIB	0.067373
PCP4	0.058428
PLAC1	0.057543
EXO1	0.055520
IL17RB	0.054792
SGK3	0.054353
DTL	0.054034
EGR3	0.052646
ITGB6	-0.052464
MND1	0.051937
CENPK	0.051814
AHRR	-0.051778
GRHL3	-0.050853
CDC45	0.050772
CENPU	0.050480
PBK	0.050361
SPC25	0.050113
MCM10	0.049822
GABBR2	-0.048987
CDC6	0.048775
SHCBP1	0.048252
RAD51AP1	0.047975
RERG	0.046880
KIF15	0.046779
BRCA2	0.045921
FANCI	0.045748
CCNE2	0.045581
TK1	0.045424
UHRF1	0.044998
E2F8	0.044742
RRM2	0.044620
PSCA	-0.044550
HS3ST3A1	0.044427
PGR	0.044361
POLE2	0.044166
UPK1A	-0.044095
MASTL	0.043960
AGR3	0.043580
ZNF367	0.043553
SPC24	0.043413
ATAD2	0.043264
KIF28P	-0.043204
CYP1A1	-0.043096
CXCL12	0.042999
PRIM1	0.042813
LINC01016	0.042677
SFXN2	0.042546
RLN2	0.042273
SNAI2	-0.042138
DDIAS	0.041768
CDCA5	0.041669
MYBL2	0.041604
WDHD1	0.041129
FABP5	0.041037
NCAPG	0.041006
NUF2	0.040811
ASF1B	0.040650
IL1R1	-0.040427
BRCA1	0.040411
CEP55	0.040189
CENPH	0.040181
COL21A1	0.040144
CENPM	0.039818
CDC7	0.039734
MAD2L1	0.039652
MELK	0.039593
GMNN	0.039445
ORC1	0.039422
CDT1	0.039228
ANLN	0.039213
TCF19	0.039181
RBM24	0.039020
BLM	0.038776
NDC80	0.038713
KIF11	0.038624
MME	-0.038497
GINS1	0.038193
OIP5	0.038143
GLA	0.038107
FOXM1	0.037853
NCAPH	0.037818
RAB31	0.037773
HEY2	0.037666
TTK	0.037620
KLK11	0.037514
UGT2B15	0.037429
TNFRSF11B	-0.037057
TYMS	0.037023
FEN1	0.037007
DUT	0.036977
TRIP13	0.036974
RAD54L	0.036969
DHFR	0.036889
CDC25A	0.036868
FHL1	0.036852
BUB1B	0.036637
MCM2	0.036602
MCM5	0.036283
UBE2T	0.036253
HCAR3	-0.036245
CDCA7	0.036159
NEIL3	0.036096
HELLS	0.036026
NCAPG2	0.036026
RFC4	0.036024
DONSON	0.035946
SKA3	0.035764
CDKN3	0.035711
KIAA0101	0.035668
TIPIN	0.035538
CHAC2	0.035186
RNASEH2A	0.035063
ERCC6L	0.035048
KNTC1	0.034946
NUAK1	-0.034871
HSPA2	0.034783
FBXO5	0.034645
RRM1	0.034456
CDK1	0.034453
CSTA	-0.034405
PCNA	0.034402
CCNA2	0.034380
BRIP1	0.034356
PLK4	0.034273
RFC2	0.033980
LMBR1	0.033932
CDCA3	0.033844
APOD	-0.033800
SPIN4	0.033788
DNA2	0.033781
MCM3	0.033730
GINS3	0.033691
CCDC83	-0.033637
GGH	0.033532
PP14571	-0.033517
MKI67	0.033504
RET	0.033448
KIF18B	0.033421
MYBL1	0.033399
PSD3	-0.033376
CENPQ	0.033363
IGSF1	0.033253
HIST2H2BE	-0.033249
CHEK1	0.033183
TMEM194A	0.033031
SMC2	0.032986
CTGF	-0.032905
LMNB1	0.032901
C1orf226	0.032697
POLQ	0.032670
FOS	0.032594
ALDH1A3	-0.032548
KIF23	0.032390
AURKB	0.032374
STIL	0.032276
FIGNL1	0.032026
IGFBP3	-0.031967
BLNK	-0.031954
CENPW	0.031868
TOP2A	0.031868
MYO1B	-0.031845
KIF4A	0.031770
CDCA2	0.031636
NTN4	-0.031605
S1PR3	-0.031529
UNG	0.031517
LIG1	0.031442
DEPDC1	0.031437
TMPO-AS1	0.031385
ESPL1	0.031385
SGK1	0.031251
NUSAP1	0.031239
RAB27B	-0.031205
BRI3BP	0.031181
ITGB3BP	0.031156
E2F7	0.031148
ABHD2	0.030999
CKS1B	0.030960
SALL4	-0.030920
DSCC1	0.030909
CDCA8	0.030837
SYTL4	0.030782
ZWINT	0.030744
NPY1R	0.030613
POLA1	0.030574
TMEM140	-0.030495
C4orf46	0.030351
UBE2QL1	-0.030229
HIST1H4C	0.030178
SPAG5	0.030041
TACC3	0.030000
PRC1	0.029990
SGOL2	0.029908
RGS22	0.029769
LIMA1	-0.029762
DEPDC1B	0.029692
SKA1	0.029635
DHRS3	-0.029590
CHEK2	0.029453
UBE2C	0.029448
VRK1	0.029444
CHRNA5	0.029328
DBF4	0.029129
ZWILCH	0.029106
DSN1	0.029094
CENPN	0.028982
PPIF	0.028979
FANCG	0.028902
CREBRF	-0.028902
GEN1	0.028873
KIF14	0.028861
RFC5	0.028775
RND3	-0.028752
FKBP5	0.028733
CDCA4	0.028718
SLC29A1	0.028710
RMI1	0.028593
RACGAP1	0.028485
HAUS1	0.028474
KIF2C	0.028435
MICB	0.028426
MCM4	0.028417
RASD1	-0.028127
HIST1H2AC	-0.028120
DLGAP5	0.028119
MCM7	0.028113
HOXC13	-0.028050
RAD51	0.028041
CENPL	0.027972
TGFB2	-0.027949
SYCE2	0.027776
RAD54B	0.027755
EZH2	0.027553
IMPA2	0.027490
TNFRSF21	-0.027448
ORC6	0.027447
STON1	-0.027415
TGFBI	-0.027296
ST3GAL1	-0.027291
VTCN1	-0.027286
BIRC5	0.027221
LOC284379	-0.027154
HSPA4L	0.027103
ACAT2	0.027077
TPX2	0.027005
ANXA3	-0.026994
PHF19	0.026978
RFC3	0.026963
APITD1	0.026918
HIST1H2BC	-0.026899
KLHL24	-0.026846
NBEA	-0.026837
C5orf34	0.026787
BAK1	-0.026779
DEPTOR	0.026724
CDH26	0.026707
NCAPD2	0.026408
MGP	0.026351
CDKN2B-AS1	-0.026299
TMSB15A	0.026282
CTPS1	0.026278
TICRR	0.026239
HIST1H3H	-0.026202
NRM	0.026117
GREB1	0.026070
FAM111B	0.026065
ENC1	-0.026046
GPR65	0.026017
MTHFD1	0.025914
EMC3-AS1	0.025892
BTG2	-0.025858
VMP1	-0.025837
CHAF1B	0.025799
MTFP1	0.025796
HIST1H2AG	-0.025721
BMF	-0.025604
CENPI	0.025602
FAM216A	0.025430
TMEM164	0.025330
FAT4	-0.025275
PPARG	-0.025262
BIK	-0.025195
C8orf4	-0.025181
TMPRSS3	0.025154
LONRF2	0.025074
RMI2	0.025030
CTNNAL1	0.024939
POLD1	0.024799
CDCA7L	0.024791
SYTL2	-0.024776
DCK	0.024773
C1orf106	-0.024763
C1orf112	0.024758
DDIT4	-0.024723
ACYP1	0.024701
HADH	0.024614
POC1B	0.024607
SERPINA3	0.024584
ISG20	0.024542
EFNB2	-0.024520
BARD1	0.024507
UGT1A6	-0.024492
WDR76	0.024434
HIST1H2BG	-0.024406
DOK7	0.024355
SLC31A2	-0.024321
CKLF	0.024302
BMP5	0.024288
FAM83D	0.024233
CMC4	0.024202
THBS3	-0.024198
CDKN2C	0.024192
NEK2	0.024185
BEX4	-0.024178
PSMC3IP	0.024156
ASPM	0.024146
FGF13	-0.024021
C8orf46	0.024006
RHNO1	0.023999
WISP2	0.023838
UPK2	-0.023804
CELSR2	0.023801
DHTKD1	0.023798
FZD2	-0.023782
LINC00052	0.023756
NUP155	0.023718
C9orf40	0.023632
AREG	0.023613
CRISP3	-0.023606
MIR22HG	-0.023599
JUNB	-0.023586
RASGRP1	-0.023577
FAM107B	-0.023543
LXN	-0.023542
N4BP3	-0.023524
AASS	-0.023492
KIAA1324	0.023483
NUDT1	0.023472
GAS2L3	0.023452
EFNA1	-0.023441
CDKN2B	-0.023431
SYBU	0.023425
SNRNP25	0.023422
LOC653602	-0.023397
TEX30	0.023371
EP300-AS1	0.023282
MCM6	0.023280
SLC47A1	0.023263
SLC26A2	0.023234
TNS3	-0.023230
PGM2L1	-0.023181
ANP32E	0.023170
HAUS8	0.023151
C5	0.023142
SLC36A4	0.023077
PRIMA1	0.023069
TMPO	0.022996
SPDL1	0.022981
RBBP8	0.022981
SELL	-0.022909
TP53INP2	-0.022903
CYP26B1	0.022883
TUBG1	0.022879
CCDC68	-0.022865
ABCG1	-0.022845
TFPI	-0.022773
HIST1H2BD	-0.022769
AK4	0.022762
FAM110C	-0.022746
GSG2	0.022686
KIF20A	0.022679
FAM64A	0.022669
ZDHHC7	-0.022610
TRIM16	-0.022593
TCF7L1	-0.022550
ARL15	-0.022548
HJURP	0.022510
POLE	0.022499
USP1	0.022492
MTFR2	0.022419
SKP2	0.022416
ZNF610	-0.022393
POLA2	0.022354
ACOT7	0.022330
LINC01341	-0.022322
EPB41L5	-0.022271
EME1	0.022266
CDC20	0.022260
CCNG2	-0.022221
ITPR1-AS1	-0.022220
SLC27A2	0.022162
DSCAM	0.022063
RAP1GAP2	-0.022048
SUV39H2	0.021966
DLEU1	0.021948
HIST1H3E	-0.021869
IRX3	0.021863
CKAP2L	0.021860
ACAA2	-0.021759
RPA3	0.021729
DERA	0.021707
DYNLRB2	-0.021661
GPR19	0.021647
GALNT4	0.021621
PTGER4	-0.021621
ABLIM3	-0.021594
CHTF18	0.021578
RECQL4	0.021516
POLD2	0.021497
XRCC3	0.021479
NDC1	0.021452
CASC5	0.021448
FANCL	0.021432
ATRIP	0.021426
MXD4	-0.021423
GRAMD3	-0.021422
OSCP1	-0.021416
PNRC1	-0.021403
SLC22A4	0.021375
MAP3K14	-0.021375
ELF3	-0.021321
ST8SIA4	-0.021279
CMSS1	0.021257
PKMYT1	0.021236
TMEM38B	0.021203
AMER2	-0.021187
CAMK1D	-0.021159
JAK2	0.021134
PLAT	0.021086
SGOL1	0.021085
TIFA	0.021076
CAMK2N1	-0.021007
DCLRE1B	0.021006
HMMR	0.020989
L1CAM	-0.020946
PRICKLE1	-0.020921
PDZK1	0.020910
FAM57A	0.020836
ZNF559	-0.020755
PLEKHM3	-0.020741
LINC00936	-0.020738
NCAPD3	0.020699
KLF5	-0.020690
YPEL5	-0.020671
FAM214A	-0.020630
ERP27	-0.020619
C6orf165	-0.020601
PLA2G10	-0.020558
LYPD1	-0.020546
SOX3	0.020546
MX1	-0.020543
UBR7	0.020519
CCDC167	0.020500
SUV39H1	0.020489
ARHGAP11A	0.020481
FANCA	0.020463
RAPGEFL1	0.020445
PTTG1	0.020438
DNAJC9	0.020403
GGCT	0.020376
ELOVL2	0.020352
TIMELESS	0.020320
CDK6	-0.020317
YPEL3	-0.020302
DIO1	0.020297
LARP6	-0.020264
CBX5	0.020260
IGDCC3	-0.020238
CTR9	0.020238
PRTFDC1	0.020222
SEMA5A	-0.020222
SLC26A11	-0.020210
CCDC34	0.020209
MIS18A	0.020174
PRSS8	-0.020148
MCEE	0.020142
ARHGAP12	-0.020095
SCCPDH	-0.020094
DZIP3	-0.019994
PAQR4	0.019985
MALL	-0.019968
DNMT1	0.019956
HIST1H2BE	-0.019928
MX2	-0.019921
TAF5	0.019908
H2AFJ	0.019899
PARPBP	0.019885
PREX1	-0.019867
LOC81691	0.019842
PPAP2C	-0.019715
SERPINA5	0.019711
CD47	-0.019695
MSH2	0.019695
GRAMD1A	-0.019691
TIPARP	0.019652
KCNK5	0.019639
TTI1	0.019613
EGR1	-0.019608
TOPBP1	0.019575