!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!ligand_name	estrogen
!ligand_id	CHEBI:50114
!cell_type	MCF-7 cells
!organism	human
!end_metadata
AGR3	0.087557
SGK3	0.073901
PKIB	0.064656
PLOD2	0.062041
HCK	0.060349
SGK1	0.056272
RERG	0.051760
NPY1R	0.050248
NRIP1	0.049015
RAB31	0.048044
AMD1	0.047648
IGFBP4	0.047517
RAMP3	0.046238
RLN2	0.044420
CA2	0.044203
CXCL12	0.044192
DDX21	0.043864
ABCE1	0.043420
NOP58	0.042454
RASGRP1	0.041543
PUS7	0.040563
OTUD6B	0.040484
NOC3L	0.039905
PGR	0.039649
STC2	0.039263
HIF1A	0.039089
GREB1	0.038976
PSCA	-0.038785
ELOVL2	0.038582
SFXN2	0.038346
PPIF	0.037537
CA12	0.036889
SEMA3C	0.036799
FAM216A	0.036311
PMAIP1	0.035852
KLK11	0.035671
PAK1IP1	0.035072
HSP90AA1	0.035065
TPD52L1	0.034852
MREG	0.034847
GALNT4	0.034823
ABHD2	0.034744
NUP35	0.034646
RET	0.034595
CMPK2	-0.034328
NMD3	0.034234
THAP9-AS1	0.034161
FABP5	0.033761
POC1B	0.033737
DTL	0.033647
TRMT10C	0.033569
KIAA0226L	0.033546
B3GALNT1	0.033303
KIF21A	0.032855
SLC26A2	0.032828
SLC38A2	0.032730
ZNF367	0.032524
MAP4K3	0.032437
HCAR3	-0.032135
GLA	0.031984
GRHL3	-0.031773
CEBPZ	0.031686
WDR3	0.031665
AHRR	-0.031553
FREM2	0.031533
RAPGEFL1	0.031523
CCT2	0.031419
HEY2	0.031277
SIGLEC15	0.031216
SYBU	0.031198
HLTF	0.030515
CEP55	0.030447
DKC1	0.030255
C6orf211	0.030075
EIF1AX	0.030030
ASNSD1	0.030004
SLC39A6	0.029848
IFI27	-0.029603
TMEM64	0.029554
TFF1	0.029483
DDX18	0.029418
TTK	0.029411
NUP107	0.029403
WDR43	0.029400
SLC6A14	0.029363
ZNF566	0.029341
BLNK	-0.029312
DNAJB14	0.029210
TMED8	0.029197
PNPT1	0.029159
USP1	0.029090
CDC6	0.029086
TMEM164	0.029051
BRIP1	0.028880
C1orf226	0.028864
SOX9	-0.028817
RPS24	0.028803
ZBTB41	0.028734
PRSS23	0.028665
ATAD2	0.028640
DBF4	0.028636
DEK	0.028611
NDC80	0.028349
SMIM5	-0.028343
HILPDA	-0.028213
KIAA1033	0.028115
ZWILCH	0.028105
CSE1L	0.028056
AGR2	0.028007
NOLC1	0.027995
HSPH1	0.027938
OAS1	-0.027878
CHD1	0.027740
LMBR1	0.027723
EIF2A	0.027719
WDR12	0.027579
SUCO	0.027354
LRP8	0.027287
MAPK6	0.027269
CALCR	0.027226
GNL2	0.027146
GNL3	0.027069
SSB	0.027059
CYP1A1	-0.026957
XPOT	0.026879
LOC400099	-0.026840
APOBEC3B	-0.026814
MSH2	0.026614
RAB30	0.026613
LRRC58	0.026533
NARS	0.026480
SPOPL	0.026464
SYTL5	0.026415
RND1	-0.026409
LYAR	0.026387
OLFML3	0.026371
C2orf54	-0.026336
GDI2	0.026323
RRM2B	0.026219
BST2	-0.026207
CCNE2	0.026180
MYBL1	0.026121
C6orf141	0.026074
BZW1	0.026032
POT1	0.025923
TCERG1	0.025913
ANG	-0.025840
WDR36	0.025809
TCF7L1	-0.025786
FZD6	0.025761
DYNLT3	0.025689
NOL11	0.025603
ZNF146	0.025570
TIPARP	0.025545
HOOK1	0.025512
MTERF3	0.025346
TIFA	0.025289
BRIX1	0.025271
SLC22A5	0.025166
FAM198B	0.025150
GMNN	0.025028
RPF2	0.024933
LRIF1	0.024916
ANLN	0.024890
STAG2	0.024818
SELL	-0.024771
CHRNA5	0.024729
KIF11	0.024698
ARHGEF26	0.024695
SHOC2	0.024652
BDKRB2	-0.024480
CDC7	0.024445
PAICS	0.024435
ZUFSP	0.024356
IPO7	0.024279
ABAT	0.024257
SLC47A1	0.024212
SLC31A2	-0.024205
DNAJA1	0.024143
TIPIN	0.024124
NDUFAF4	0.024124
BMF	-0.024115
ARRDC4	0.024069
CCDC47	0.024031
TMEM140	-0.023920
PDZK1	0.023845
DCTN6	0.023805
SUPT16H	0.023803
MYB	0.023781
EIF2S1	0.023697
GSKIP	0.023643
EDEM3	0.023614
VRK1	0.023553
ZNF516	0.023502
FOS	0.023481
SRFBP1	0.023465
TMEM45A	-0.023428
SLMO2	0.023380
EFCAB10	0.023337
EFNA1	-0.023321
C10orf10	-0.023302
AMMECR1	0.023262
KRT13	0.023221
PPAT	0.023192
ARRDC3	0.023168
BMI1	0.023150
RHOBTB1	0.023097
TMTC3	0.023065
CBX3	0.023055
RINT1	0.023037
NBN	0.023012
TFRC	0.023008
VAMP7	0.022968
HS3ST3A1	0.022944
RBBP8	0.022935
CTPS1	0.022881
PIK3R1	0.022869
ELF3	-0.022844
NAA50	0.022825
ZBTB6	0.022794
FYTTD1	0.022784
LOC100506325	0.022777
IFI35	-0.022726
ZRANB2	0.022682
WWP1	0.022676
ZNF239	0.022614
KRT15	0.022596
RRP15	0.022562
ZNF14	0.022553
APOBEC3A	-0.022511
B3GALT4	-0.022452
IRF7	-0.022449
UGDH	0.022448
CRNKL1	0.022363
PTRH2	0.022312
ARL13B	0.022299
POLE2	0.022298
BAZ1A	0.022294
GNPNAT1	0.022269
NEK7	0.022223
UCK2	0.022211
KPNA3	0.022205
MASTL	0.022194
ZDHHC23	0.022075
ZNF12	0.022063
SRM	0.022057
CDCA7	0.022047
DHRS3	-0.021988
UGCG	0.021979
RIOK1	0.021916
AHSA1	0.021874
GPBP1	0.021871
USP16	0.021864
LOC101928940	0.021853
RPS6KB1	0.021843
SGOL2	0.021834
ZFYVE19	-0.021823
EIF3J	0.021812
SYNDIG1	0.021740
BRCC3	0.021693
ATP13A3	0.021692
SRSF10	0.021642
SLC16A6	0.021607
RECQL	0.021606
BAK1	-0.021597
CAV1	0.021549
SRSF7	0.021547
TAX1BP1	0.021535
PPL	-0.021530
ORC3	0.021518
ZMPSTE24	0.021502
FAM222A-AS1	0.021490
SNHG15	0.021462
SRP72	0.021453
POGLUT1	0.021444
DNAJC10	0.021440
SACS	0.021431
RPE	0.021412
LYPD3	-0.021395
NOL8	0.021391
SCYL2	0.021383
FFAR2	-0.021378
EMC2	0.021355
RMI1	0.021348
SELT	0.021335
ASUN	0.021328
NUPR1	-0.021327
RAD51AP1	0.021327
PRKRIR	0.021304
GEMIN5	0.021281
SLC38A1	0.021201
RANBP2	0.021173
GPR133	-0.021166
METTL8	0.021133
BTAF1	0.021131
PIGW	0.021106
SLC44A3	-0.021090
LINC01087	0.021085
PTPLB	0.021058
RARS	0.021003
C1orf85	-0.020984
MRPL3	0.020974
CAND1	0.020966
HEXIM2	-0.020891
ZNF354A	0.020864
C2orf69	0.020837
MAK16	0.020829
SLC25A32	0.020818
KISS1R	-0.020794
GPD1L	0.020786
HAT1	0.020769
SEH1L	0.020760
PRRT3	-0.020705
UHRF1	0.020686
ASB9	-0.020681
ELF1	0.020678
TRPS1	0.020671
CLDN9	-0.020650
IFITM1	-0.020646
VPS9D1	-0.020605
LOC653602	-0.020548
RFC3	0.020535
INTS2	0.020528
ETF1	0.020498
IL1R1	-0.020494
TRMT11	0.020491
PNPLA8	0.020410
C6orf120	0.020409
CHAC2	0.020381
TRAPPC8	0.020341
IL10RB	-0.020339
SRSF1	0.020338
EXOC5	0.020318
TAF9	0.020274
SIAH2	0.020238
ID1	-0.020209
SLC39A10	0.020171
ZNF267	0.020148
CPNE3	0.020138
HMMR	0.020126
ATF1	0.020104
ISG15	-0.020087
HAUS1	0.020063
TIAM1	0.020029
TPTE	0.020022
DDX1	0.019983
DEPTOR	0.019970
DCUN1D4	0.019970
UBE2Q2	0.019969
TBC1D23	0.019954
CSRNP1	-0.019949
SP6	-0.019941
SCAMP1	0.019853
FAM46B	-0.019838
KIF5B	0.019823
ARMC1	0.019770
PALM3	-0.019767
PRMT3	0.019754
ARFGEF1	0.019740
FKBP5	0.019727
EGLN3	-0.019678
SRP19	0.019647
CMTR2	0.019639
PPM1K	0.019625
NT5C3A	0.019614
IGDCC3	-0.019593
CTR9	0.019589
LARP4	0.019563
MOB1B	0.019560
SLC9A3R1	0.019546
DHX40	0.019544
G2E3	0.019522
DKFZP434I0714	0.019517
NCBP1	0.019513
HIST2H2AA3	-0.019499
RRN3	0.019497
TP53INP2	-0.019471
SNAPC1	0.019467
GALNT7	0.019458
ZNF195	0.019415
TPBG	0.019412
ZBTB2	0.019337
WFDC21P	-0.019330
MTR	0.019316
SMARCA5	0.019315
PLS1	0.019315
EIF5B	0.019284
RNF43	-0.019279
IFIT1	-0.019274
SNRPD1	0.019256
DNAJC2	0.019241
TBK1	0.019231
SOCS2-AS1	-0.019225
CRIP1	-0.019206
ATP6V1C1	0.019190
SPAST	0.019174
TXLNG	0.019156
MKNK2	-0.019104
GLIS2	-0.019081
SMC4	0.019075
RANBP6	0.019047
TTC37	0.019042
USP31	0.019036
KCTD3	0.019020
GMFB	0.019002
TOX2	-0.019002
CIPC	0.018983
GRB7	-0.018972
PCDH8	-0.018959
GNA13	0.018950
PRPF40A	0.018936
MYC	0.018906
FBXO5	0.018864
HMGB1	0.018857
MSL2	0.018854
PTK6	-0.018830
PANK3	0.018823
PCP4	0.018818
BIK	-0.018815
DFNB31	0.018801
RPP40	0.018765
RGS22	0.018762
GTF2F2	0.018759
VTA1	0.018707
CNOT8	0.018692
COPS5	0.018652
PRPF4B	0.018651
SLC7A5	0.018645
EPS15	0.018640
ZBTB11	0.018611
ANKRD35	-0.018605
SERBP1	0.018601
TMEM181	0.018594
CERS4	-0.018580
IRF9	-0.018580
C1orf106	-0.018572
C12orf66	0.018556
AMOTL2	-0.018547
ICE1	0.018530
FKBP4	0.018524
SF3B1	0.018492
ZNF296	-0.018492
LONRF2	0.018474
RAD50	0.018461
SHISA2	-0.018456
FAM174B	-0.018456
ZMYND11	0.018452
SLC19A2	0.018448
EIF4A2	0.018441
MRPL1	0.018435
SIL1	-0.018426
ZC3H14	0.018423
EPN3	-0.018423
ALDH1A3	-0.018404
PRKG1-AS1	-0.018401
FZD2	-0.018397
TRIM59	0.018392
MTIF2	0.018388
PALB2	0.018376
SPSB2	-0.018361
C9orf91	0.018357
HNRNPA3	0.018345
LYSMD4	-0.018335
RB1CC1	0.018256
GTPBP4	0.018247
FIGNL1	0.018183
MRPS35	0.018171
EIF2S2	0.018169
EMB	0.018148
METTL1	0.018142
FAM217B	0.018127
CCDC59	0.018119
ZC3H15	0.018109
WDR75	0.018107
TTC3	0.018095
GIN1	0.018091
IGFBP3	-0.018072
STC1	0.018069
BCAS2	0.018047
LOC100129129	-0.018035
LMCD1	-0.018014
RABEP1	0.017994
QSER1	0.017981
GOLT1B	0.017936
DARS	0.017929
CTGF	-0.017912
RNASE4	-0.017905
CHST7	-0.017887
MIF-AS1	-0.017871
BIRC2	0.017871
SAT2	-0.017869
CENPK	0.017854
DRD1	-0.017851
SVIP	0.017848
NCOA4	0.017823
BIRC6	0.017818
CBWD1	0.017805
PALM	-0.017798
NUDCD1	0.017771
SMC3	0.017767