!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Mus musculus
!cell_type	Liver
!drug_id	CID 90470904
!drug_name	Leptin
!organism	Mouse
!end_metadata
CYP4A11	-0.126978
SCD	0.109243
CA3	0.106561
DBP	0.097242
PPP1R3G	0.089278
AMICA1	0.085064
INSIG2	-0.084856
MFSD2A	-0.082417
TFF3	0.081719
RGS16	0.080736
TIMMDC1	0.080116
GSTA5	-0.074690
FOXQ1	0.074176
HLA-DRB5	0.073613
CELA2A	0.071259
GLDC	-0.070423
HLA-DQB1	0.068881
CD74	0.068089
ILDR2	-0.065020
CTGF	-0.061461
ACOT1	-0.060426
CHI3L1	-0.060262
SERPINA12	0.059875
LCN2	-0.059703
GADD45G	0.058926
SUOX	-0.058751
HLA-DQA1	0.058391
APCS	0.057785
ASL	-0.057724
CXCL13	-0.057035
HGFAC	0.056740
NUDT7	0.056514
ND4L	-0.056128
OAT	-0.055225
BHMT	-0.054756
FKBP11	0.054141
CES3	0.054016
C8A	0.053760
ABCC3	-0.053657
RETSAT	-0.053414
HSD17B6	0.052826
SERPINA6	0.052686
CD1D	-0.052499
SLC16A5	-0.052204
RBP1	0.051882
PRTN3	0.051736
MLXIPL	0.051626
PLIN5	-0.050586
EGR1	0.050290
CHPT1	-0.050065
TMEM120A	-0.049976
STBD1	0.049900
RND2	-0.049762
FMO3	-0.049681
MGST1	-0.049384
CHAC1	0.049257
ORMDL3	-0.048537
PSMB9	0.046827
ISG15	0.046190
TREH	-0.046161
ND5	0.046077
BMPER	-0.045953
AACS	0.045893
ALDOB	-0.045668
SGK1	0.045372
C8B	0.045255
DNAI1	0.044867
GAMT	0.044703
FOLR2	0.044700
TAT	-0.044659
IGFBP2	0.044635
SLC45A3	-0.044019
CREG1	-0.043834
HSD17B2	0.043665
TMEM51	0.043587
KLF2	0.043053
CSRNP1	0.043002
TTPA	-0.042506
USP18	0.042079
HSBP1L1	0.042049
SLC25A15	-0.041936
CYP3A7	-0.041837
AFM	0.041627
HLA-DMA	0.041545
SLC41A2	-0.041495
LGALS3	0.041029
GYS2	0.040728
CYP8B1	-0.040705
DCLK3	0.040508
GSTM1	-0.040504
ACOX2	-0.040483
CCND1	0.040411
NAT8B	0.039794
SLC25A10	-0.039469
ALDH1A1	-0.039392
CYP2B6	-0.039207
UBA7	0.039039
HIST1H2AM	0.039038
INMT	0.039008
NRN1	0.038912
PPARGC1B	0.038899
CPT2	-0.038782
C19orf67	-0.038267
DUSP1	0.038253
LRTM1	-0.038249
PCK1	-0.038174
PRSS8	0.038095
CYP7A1	0.037751
CYP17A1	-0.037688
DCT	-0.037622
EMP1	0.037564
FAM73B	-0.037226
DDC	-0.037050
ACTN1	0.037041
FABP5	0.036826
TIMP1	0.036628
TMPRSS2	-0.036456
PHLDA1	0.036335
AGPAT2	-0.035928
BCL6	0.035788
NUDT6	-0.035690
TMEM30A	0.035682
PDE6H	0.035534
CENPL	0.035192
TYROBP	0.035191
GBP3	0.035153
ENHO	0.035073
RPL13A	0.034938
CCL5	0.034895
LHPP	-0.034876
GLRX	-0.034875
ARHGEF19	-0.034772
ETNK2	0.034760
EMP3	0.034728
UPP2	0.034700
HIST1H2AA	0.034525
ST3GAL5	-0.034473
LPGAT1	-0.034414
SLC22A5	-0.034380
HAPLN4	-0.034291
CDA	-0.034211
TMEM39A	0.034181
PPIB	0.034116
XBP1	0.034085
CISH	0.034055
ACOT4	-0.033996
C10orf10	0.033641
NREP	0.033554
SOCS3	0.033470
IFIT3	0.033459
RPL12	0.033225
TMIE	-0.033187
EFNA1	0.033170
NAT8	-0.033110
RPL18A	0.032875
CIRBP	-0.032834
APOBEC1	0.032736
GLS2	-0.032702
ARL5A	-0.032683
TDO2	-0.032673
GBP4	0.032638
AQP8	0.032536
PLIN2	-0.032528
RNF145	0.032441
HIST1H2AE	0.032224
TPST1	0.032177
AASS	-0.032084
ENTPD5	-0.032067
MMD2	-0.032026
CAMK2N2	-0.032016
FOS	0.031946
HIST1H2AH	0.031921
TSKU	-0.031920
HIST1H2AG	0.031798
SULT1E1	-0.031752
CASP1	0.031699
F11	0.031449
NNMT	-0.031334
PTGIS	0.031275
PLEKHB2	-0.031162
OPLAH	-0.031159
FST	0.031116
KCTD2	0.031043
CKB	0.030971
WFDC2	-0.030927
MGP	0.030926
CMBL	-0.030916
LBP	-0.030877
IRF2	0.030826
PLAC8	0.030793
HLA-E	0.030775
ETHE1	-0.030724
TTC38	-0.030667
MCM10	0.030645
CREB3L3	-0.030640
CYBA	0.030604
KLKB1	0.030396
FAM195A	-0.030375
SDS	-0.030189
GCHFR	-0.030164
IRF7	0.030022
RND3	-0.029964
ANXA5	-0.029945
PPA1	-0.029868
JUNB	0.029763
TMED3	0.029718
SCAMP1	0.029597
IGFBP1	-0.029579
SDF2L1	0.029528
ACADM	-0.029413
FKBP5	-0.029379
FBXO36	-0.029176
SNTG2	0.029174
SLC25A20	-0.029170
SH3BGRL3	0.029036
FCHSD2	0.029023
EPHX1	-0.028976
PID1	-0.028946
CXCL2	0.028928
SUV420H2	0.028917
BAX	0.028857
FFAR3	-0.028543
ODF3B	-0.028515
TMEM200B	-0.028483
IGFBP5	-0.028453
ALAD	0.028418
PARP16	0.028369
ATP6V0A1	-0.028353
C17orf96	-0.028324
HAO1	0.028310
BHLHE40	0.028230
ACAA1	-0.028198
CTH	-0.028143
FOXA3	0.028101
C19orf80	0.028002
IRF5	0.027994
ECH1	-0.027930
SLC25A33	0.027928
C1QA	0.027911
MZB1	0.027784
BCAP29	-0.027760
CLDN5	0.027741
SPATA2L	0.027687
APOA5	-0.027663
FAM210B	-0.027608
SERPINA1	0.027575
HLA-DMB	0.027514
EIF4EBP1	0.027490
PARVA	-0.027260
DPP7	0.027224
NIPAL1	0.027024
CLDN3	0.026983
DDIT4	0.026922
PIM3	0.026909
SLC38A4	-0.026854
PDK4	-0.026768
HTATIP2	-0.026689
TMEM86A	0.026558
GPR146	0.026541
CLEC4F	0.026485
ALDH16A1	-0.026473
DDAH1	-0.026379
SDC1	-0.026377
RPL39	0.026320
FXYD5	0.026305
RASSF3	0.026244
RPS21	0.026206
FH	-0.026190
DCTPP1	0.026162
ALDH1L1	-0.026129
ACSF2	-0.026125
CYP4A22	-0.026100
GNG10	0.026087
TMEM141	-0.025991
MPV17L2	-0.025986
TFRC	-0.025984
MRAP	-0.025914
DPYD	-0.025844
CCDC120	-0.025840
RPL26	0.025836
RPS16	0.025682
IRAK3	-0.025668
C1QC	0.025577
C8orf82	-0.025568
MARCH6	-0.025551
WNT5B	-0.025538
FAM13B	-0.025524
RCL1	0.025482
UGT3A1	-0.025436
ABHD17A	-0.025340
P2RY6	0.025337
CCR5	0.025314
AQP1	0.025233
AVPR1A	0.025202
SYVN1	0.025167
SLC38A2	0.025146
ALDH4A1	-0.025080
TM4SF4	-0.025043
ASS1	-0.025012
KISS1	-0.024896
COLGALT1	-0.024894
SELK	0.024857
GC	-0.024711
ASNS	-0.024663
CLPX	-0.024605
UBE2E2	-0.024577
HIST1H2AJ	0.024547
NENF	0.024528
SAMD9L	0.024376
COTL1	0.024285
CD14	-0.024277
LY86	0.024276
ABCA6	-0.024136
C8orf88	-0.024119
ABCB4	-0.024019
SERINC3	-0.023987
RPL22	0.023948
PLEKHB1	-0.023947
FMO5	-0.023899
BAG3	-0.023882
APOA4	-0.023849
NRG4	-0.023848
ABAT	-0.023829
GPR182	0.023818
CD86	0.023815
SDSL	-0.023771
LY6E	0.023766
ECI1	-0.023765
SMPD3	-0.023672
HMGCS2	-0.023647
RAMP2	0.023550
ANGPTL4	-0.023462
BCL7A	0.023436
LEPROT	0.023403
DUSP28	-0.023381
GDE1	-0.023349
SPINK1	0.023219
RPS12	0.023204
C1QB	0.023181
GLTSCR2	0.023169
FAM26F	0.023123
TFR2	-0.023120
TMEM134	-0.023071
CDHR5	-0.023068
MUM1	0.023065
HSD17B7	-0.023053
FPGS	-0.023025
ELOVL6	0.022968
KIAA1467	-0.022949
TAP1	0.022940
ARL8A	0.022920
PLD4	0.022872
ACMSD	-0.022858
CENPM	-0.022856
FCGR2A	0.022846
LDHA	-0.022831
ETNPPL	-0.022807
POLR1C	0.022780
NFE2L1	-0.022690
S100A10	-0.022663
S100A6	0.022661
PEX16	-0.022656
CENPA	0.022625
COX7B	-0.022600
SGK2	-0.022593
GRN	-0.022511
ALDOA	0.022486
WSB1	0.022480
DNAJC12	0.022476
SELENBP1	0.022443
FAM3C	0.022414
LBH	0.022395
BLCAP	-0.022368
WBP5	0.022333
ICAM2	0.022332
SLC8B1	0.022332
CLTB	-0.022329
CA14	-0.022316
PDILT	0.022306
RPS5	0.022242
CD63	0.022231
ACAT1	-0.022211
HEXIM1	-0.022193
HPGD	0.022191
SUGCT	-0.022148
ODC1	-0.022137
CTNNBIP1	-0.022135
GJA4	0.022096
AGXT2	-0.022083
EI24	-0.022078
RIPK4	-0.022068
SLC30A1	-0.022043
SPG7	-0.021993
CYP4F8	-0.021961
TOMM40L	0.021956
KRT23	-0.021952
PARK7	-0.021940
ARNTL	-0.021938
NUDT8	-0.021922
PTTG1IP	-0.021898
LAPTM5	0.021898
COMT	0.021861
SRD5A1	0.021804
CRCP	-0.021787
PHLDA3	0.021780
MED16	-0.021779
SPARC	0.021771
CSRP3	0.021736
C7orf50	0.021715
CRAT	-0.021678
HOGA1	-0.021656
GSTK1	-0.021655
GCGR	0.021651
PPP1R3C	-0.021642
LTC4S	0.021600
GUCA1A	0.021595
ELOVL2	0.021584
DNAJB9	0.021559
HK3	0.021551
NT5C3A	0.021525
PLIN4	-0.021507
MRPL50	0.021482
AHCY	-0.021480
LPAR6	0.021467
UGT1A6	-0.021459
FAM134A	0.021393
AP2A2	-0.021391
HBB	-0.021382
ARL6IP1	-0.021374
ST5	-0.021371
IGFBP3	-0.021333
SEC23A	-0.021307
C6	0.021250
LAMB3	-0.021219
VEGFA	0.021211
SEMA4A	0.021205
OLFML1	0.021185
PLEKHF1	0.021174
HIST1H1C	-0.021170
GIMAP6	0.021128
ERLIN1	0.021121
SLC6A13	-0.021116
OXCT1	0.021112
MACROD1	-0.021102
MYADM	0.021085
MOGS	0.021082
KLHDC10	-0.021075
MOCS2	-0.021055
ATOX1	-0.021038
ZFP36	0.021007
ITFG3	-0.020994
ZNF574	-0.020989
MAN2A1	-0.020988
ADAP2	-0.020961
CTSV	-0.020950
SQSTM1	-0.020923
ACTN4	-0.020920
HPD	-0.020879
DCPS	0.020795
EXTL1	-0.020783
PYGL	0.020775
MAF1	0.020699
ACOX1	-0.020698
C9orf16	-0.020692
SLC1A2	-0.020683
TTC39C	0.020665
CNPY2	0.020625
VEGFB	0.020613
MRPS6	0.020588
LSM6	0.020588
RPL3	0.020575
TRA2A	0.020565
DECR1	-0.020509
HSD17B4	-0.020494
VSIG4	0.020486
SPSB2	0.020440
ACAD10	-0.020439
ARRB2	0.020416
LENG9	0.020406
TK2	0.020354
SFXN1	-0.020343
AIF1	0.020328
TMEM150A	0.020322
TMEM11	0.020237
FTCD	-0.020215
GPT2	-0.020191
DDOST	0.020151
DEDD2	0.020137
KMO	-0.020127
EEF1B2	0.020115
NGEF	0.020108
IP6K2	-0.020104
SCIMP	0.020095
MAST3	0.020085
SULT1C2	0.020068
PNPLA7	0.020057
STARD4	0.020056
SLC22A25	0.020052
NRP1	0.020042
DOK2	0.020029