!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!drug_name	Nilotinib
!smiles	CC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)N3C=C(N=C3)C)C(F)(F)F)NC4=NC=CC(=N4)C5=CN=CC=C5
!drugbank_id	DB04868
!pubchem_cid	644241
!cell_type	K562 cells
!organism	human
!end_metadata
HBZ	0.175572
BLVRB	0.150527
OAT	0.149011
NMU	-0.137738
GYPB	0.136630
HBD	0.131689
MYC	-0.123566
VIM	-0.123350
GYPA	0.117590
LDHA	-0.115663
APOC1	0.109840
ASNS	-0.104556
HMBS	0.101517
IARS	-0.101242
HBE1	0.097842
TSC22D1	0.097130
ODC1	-0.096526
CHCHD2	-0.096425
CYCS	-0.095138
ALAS2	0.094739
HNRNPA2B1	-0.092340
SOCS2	-0.092176
NCOA4	0.091890
MTHFD2	-0.088239
GARS	-0.083555
H2BFS	-0.082427
ACTG1	-0.080759
ALDOA	-0.075721
RAN	-0.071891
LAPTM4B	-0.070796
TRIB3	-0.070698
FTH1	0.070450
SAMSN1	-0.069610
SAT1	0.068702
ENO1	-0.066181
CCND3	0.066148
DDIT4	-0.065096
HIST1H1C	-0.065033
SMYD3	-0.064693
IFITM2	-0.064607
HBB	0.064430
PPA1	-0.063194
PRDX1	-0.062073
WARS	-0.061539
TXNIP	0.061154
HINT1	-0.061121
NHP2	-0.060505
TMSB10	-0.060242
IFITM1	-0.060117
DDX21	-0.060003
CTSL	0.059982
MIF	-0.059303
UCP2	0.058870
C11orf21	0.058815
NME1	-0.058483
TARS	-0.057869
LMO2	0.057540
CPOX	0.056944
MAT2A	-0.056677
ATF4	-0.056343
XK	0.055418
HSPA5	-0.055095
CTSH	-0.055028
KARS	-0.054495
RPL36A	0.054380
GAPDH	-0.054076
VAPA	-0.053940
RPS27	0.053532
HNRNPAB	-0.053404
PFN1	-0.052602
PTMA	-0.052601
ATP5B	-0.052489
RSL24D1	-0.052190
NCL	-0.051652
MYL4	0.050660
CCT5	-0.050621
TESC	0.050525
SORD	0.050523
NPM1	-0.049229
CNBP	-0.049227
HSPD1	-0.049199
RAP1B	-0.049161
RSRP1	0.049126
VDAC2	-0.048504
RPL39	0.048380
WBP5	0.048018
SLC7A5	-0.047577
YARS	-0.046986
TFRC	0.046847
NDUFAB1	-0.046765
H2AFZ	-0.046513
SNRPD2	-0.046417
XPOT	-0.046393
SARS	-0.046378
ACTB	-0.046266
SH3BGRL	0.046245
EIF4A2	0.046128
SERPINF1	0.045584
BNIP3L	0.045338
SLIRP	-0.044845
NARS	-0.044761
NARF	0.044647
SLC25A37	0.044320
TCEA1	-0.044256
RPLP1	0.043905
MRPL3	-0.043891
NDUFS6	-0.043014
MCTS1	-0.042828
CD24	-0.042281
IFITM3	-0.042245
PPOX	0.041757
DDX5	-0.041651
CEBPB	-0.041472
ASAH1	0.041433
PRDX4	-0.041262
ASH2L	0.041240
GGCT	-0.041121
HIST1H4C	-0.040898
SPTA1	0.040893
CFL1	-0.040887
FTH1P5	0.040592
SLC38A2	-0.040259
CROCCP2	0.039848
DLK1	0.039808
ATP5F1	-0.039462
SNRPG	-0.039116
DDX39A	-0.039044
LDHB	-0.038836
PGAM1	-0.038626
HSPA8	0.038591
SEPP1	0.038226
CMTM6	-0.037874
HSP90AB1	-0.037717
FEZ1	0.037442
HSPA1A	0.037274
CAT	0.037065
PTP4A2	-0.037057
EIF1	-0.036771
DLD	-0.036758
TP53BP2	0.036484
KEL	0.036469
YWHAQ	0.036452
NDUFC2	-0.036401
CYP3A5	0.036142
SET	-0.036059
NACA	0.035956
LYPLA1	-0.035625
LRPPRC	-0.035593
PHB2	-0.035570
C1QBP	-0.035441
CREG1	0.034952
RPL9	0.034625
PIM1	-0.034174
IQGAP2	0.033873
SNRPA1	-0.033849
SLC25A5	-0.033793
S100A11	-0.033620
GHITM	-0.033501
PRKCB	-0.033351
REXO2	-0.033286
CD69	-0.033272
FECH	0.033269
HSPA9	-0.033135
YPEL5	0.032936
HIST1H2BE	-0.032925
COX8A	-0.032914
KLF10	0.032771
POLR2G	-0.032487
MDH2	-0.031957
MDH1	-0.031811
PTGES3	-0.031756
AARS	-0.031732
ANXA1	-0.031596
PARK7	-0.031555
PTBP1	-0.031535
BHLHE40	-0.031381
SNRPD3	-0.031372
HIST1H3H	0.031358
PPP1CC	-0.031223
PODXL	0.031201
EEF1B2	-0.031052
MYB	-0.031021
CAB39	-0.030915
ERH	-0.030887
CARS	-0.030830
LRRC47	-0.030798
SLC4A1	0.030443
EIF2S2	-0.030433
HIST3H2A	0.030357
CTSC	-0.030194
KLF1	0.030119
TSPAN13	0.029952
RANBP1	-0.029835
CCNB1IP1	-0.029777
NOP10	-0.029677
HHEX	-0.029634
EIF4A1	-0.029625
RPS14P3	-0.029621
MRPS30	-0.029561
AMIGO2	-0.029539
UQCRFS1	-0.029507
PSMG1	-0.029482
TRA2B	-0.029297
NFE2L2	-0.029111
CKS1B	-0.029073
SRSF3	-0.029056
TPT1	0.028924
HAX1	-0.028752
RPL37	0.028686
C14orf2	-0.028223
RPS25	0.028141
IDH1	-0.028057
RPL27	0.028034
TMEM14B	0.027998
LASP1	0.027960
CTNNB1	0.027899
GYPE	0.027687
GYPC	0.027662
CLIC1	-0.027618
NQO2	-0.027602
LSM8	-0.027584
FAXDC2	0.027529
SMNDC1	-0.027443
AURKAIP1	-0.027313
DNAJC12	-0.027240
BTG1	0.027150
SEH1L	-0.027116
FAM60A	-0.026880
EIF3G	-0.026671
KIAA1551	0.026543
NDUFAF4	-0.026523
LGR4	0.026468
ZMPSTE24	-0.026249
SNRPF	-0.026063
AHCY	-0.025865
RHAG	0.025858
ARPC5L	-0.025700
HIRA	-0.025562
COX5A	-0.025490
TMOD1	0.025454
YBX1	-0.025413
CCND2	-0.025399
SDCBP	0.025394
PPIA	-0.025315
UFD1L	-0.025242
PRDX6	-0.025160
SSBP1	-0.025156
GAGE3	-0.025112
PGK1	-0.025099
FBL	-0.025015
PTPRO	0.024933
OLA1	-0.024803
ARL4A	-0.024803
EIF4H	-0.024715
CCT4	-0.024679
HIST1H2BF	-0.024657
TUBB4B	-0.024651
CITED2	0.024582
CSNK2B	-0.024460
RAB27A	-0.024367
SRSF2	-0.024351
RPS16	-0.024338
ETFA	-0.024323
RHCE	0.024322
NDUFA13	-0.024182
RBMX	-0.024133
GLRX2	-0.024100
JTB	-0.024075
UBE2E1	-0.023952
MRPL15	-0.023944
RPS18	0.023901
ZNF706	-0.023877
GABARAPL2	0.023706
BPGM	0.023703
UQCR11	-0.023673
RPL30	0.023578
NSA2	-0.023480
TUFM	-0.023469
EEF1A1	0.023451
ATP5E	0.023416
OSBPL9	0.023415
RFC4	-0.023403
TXN	-0.023345
TUBA1A	0.023339
RPL23A	0.023334
EGR1	-0.023299
DBF4	-0.023293
KRT19	0.023277
MAGEA3	-0.023265
PFDN5	0.023249
CCT6A	-0.023127
ADD2	0.023112
ACTN4	-0.023103
FXYD5	-0.022986
UROD	0.022950
RPS3A	0.022914
SHMT2	-0.022895
UQCRQ	-0.022887
HMGB1	-0.022832
EIF4A3	-0.022778
RHD	0.022682
CFAP20	-0.022672
COL18A1	0.022668
DHX15	-0.022650
XIST	0.022635
HSPE1	-0.022605
TUFT1	0.022588
TUBB	-0.022573
SNRPB	-0.022557
AMMECR1	0.022530
FH	-0.022513
EIF3I	-0.022449
PSMA6	-0.022432
STAM	0.022430
EDF1	-0.022427
MRPS35	-0.022341
SCD	-0.022340
RPS10	0.022311
ATIC	-0.022306
SLC25A6	-0.022201
SEC11A	-0.022177
MARS	-0.022176
HSPA14	-0.022169
MGST3	0.022166
PNISR	0.022122
DMXL1	0.022065
TAF9	-0.022062
UQCR10	0.022044
RPS13	0.021995
GTF3A	-0.021871
TPI1	-0.021851
MSN	-0.021840
CCT7	-0.021804
MTIF2	-0.021785
HNRNPA1	0.021756
SCPEP1	0.021618
EIF4EBP1	-0.021599
LBH	0.021570
PRMT1	-0.021499
NAE1	-0.021457
GTF2A2	-0.021392
RELN	0.021374
HSD17B12	-0.021367
RPL26	-0.021336
H3F3B	-0.021313
DNAJC2	-0.021282
RPLP0	0.021274
SPCS1	-0.021220
NHP2L1	-0.021199
VDAC1	-0.021134
TBPL1	-0.021082
RPL21	0.021051
FAM129A	-0.020985
RPS24	0.020982
SDF2L1	-0.020899
DYNLL1	-0.020867
EEF1D	-0.020866
PAICS	-0.020825
UQCRH	-0.020748
SLC30A1	0.020671
HERPUD1	-0.020669
NT5C2	-0.020628
UTP11L	-0.020605
SLC39A14	-0.020599
SLC35E2B	0.020590
RTN4	0.020508
OPHN1	-0.020459
CELF2	-0.020440
CCT8	-0.020414
CENPU	-0.020379
SNRPD1	-0.020278
UTP6	-0.020216
ZNF273	0.020214
NUP107	-0.020180
MAD2L1	-0.020164
EEF2	-0.020097
TRIAP1	-0.020072
RBM15	-0.020070
SERBP1	-0.020012
RPS15A	0.020000
HBQ1	0.019990
CDIPT	0.019988
PSMA3	-0.019951
TMED2	-0.019947
RAC1	-0.019888
RPL31	0.019869
SLC2A1	0.019818
NDUFB4	-0.019768
UGP2	-0.019758
COCH	-0.019749
NOLC1	-0.019725
TNNI3	0.019714
CBFB	-0.019684
TJP2	0.019675
CCT3	-0.019638
TIMM13	-0.019629
PPIB	-0.019600
HIST1H2AC	-0.019559
TBCA	-0.019555
TSPYL4	0.019511
MYL12B	-0.019507
NPL	0.019488
ARMCX6	0.019486
RHOG	-0.019480
KAT2B	0.019463
PHGDH	-0.019451
C14orf166	-0.019398
CTSB	0.019395
SFPQ	-0.019368
CISD1	-0.019356
STRAP	-0.019342
SYNGR3	-0.019342
SAE1	-0.019301
RAB11FIP1	-0.019185
BZW2	-0.019171
CDKN1C	0.019105
TOMM20	-0.019094
TAX1BP3	0.019033
IMPDH2	-0.019032
LRRC59	-0.019009
POLR2H	-0.018991
SUMO2	0.018842
GDF15	-0.018842
UBB	0.018824
FOXO3	0.018796
GPX4	-0.018780
GSTO1	-0.018780
UAP1	-0.018780
KRT18	-0.018761
UBE2N	-0.018734
RPL34	0.018733
CLTC	0.018700
SLC2A3	-0.018668
TM9SF3	0.018660
ANKRD27	0.018641
DKC1	-0.018635
TUBA1C	-0.018498
MAGEA6	-0.018397
PSAP	0.018394
NDUFV1	-0.018392
ATP5L	-0.018369
SLC30A10	0.018323
AGPAT5	-0.018282
UBE2S	-0.018281
RPS27A	0.018254
PPIH	-0.018177
MTHFD1	-0.018165
POP7	-0.018151
FADS1	-0.018136
EPM2AIP1	0.018078
YRDC	-0.018020
RNASE1	0.018020
CUTA	-0.018019
METTL7A	0.017981
FNTA	-0.017963
SERINC1	0.017951
MAPK6	-0.017944
RPL18	0.017890
HADHB	-0.017707
CHPT1	0.017702
CAP1	-0.017686
TMED5	-0.017673
PBK	-0.017667
MXRA7	0.017655
SRSF7	-0.017643
MYH10	0.017629
NAP1L1	-0.017594
EFEMP1	0.017593
TCF4	0.017558
MCM6	-0.017551
MAK16	-0.017545
SRP9	-0.017539
RPS29	-0.017538
AP2S1	-0.017523
PROCR	0.017522
IRAK1	-0.017510
RPS23	0.017499
IMP3	-0.017484
YWHAH	0.017445
EMP3	-0.017418
ECHS1	-0.017417
RPS27L	0.017404
CTSE	0.017387
CCDC59	-0.017366
RPS26	-0.017313
DDIT3	-0.017296
SLC39A8	0.017296
CTH	-0.017239
EIF3D	-0.017195
EZH2	-0.017193
ATP6V0B	-0.017134
NEDD8	-0.017117
RPL13A	0.017084
PRR13	-0.017071
POGK	-0.017046
CD63	0.017015
HIST1H2BK	-0.017012
ALG8	-0.017007
NDUFA1	-0.016984
ICAM4	0.016965