!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	Anastrozole
!smiles	CC(C)(C#N)C1=CC(=CC(=C1)CN2C=NC=N2)C(C)(C)C#N
!drugbank_id	DB01217
!pubchem_cid	2187
!cell_type	Breast Cancer tumor core biopsies
!organism	human
!end_metadata
CYP2B7P	-0.147157
SCGB2A2	-0.113708
CPB1	-0.109518
SERPINA3	-0.096363
TFF1	-0.093902
STC2	-0.085046
AGR3	-0.080694
GGH	-0.077832
SCGB1D2	-0.073794
DHRS2	-0.070694
EPHX4	0.069236
AGR2	-0.068253
GABRP	-0.066211
CPA3	0.065127
KRT15	-0.062709
MELK	-0.062667
CXCL11	-0.062476
KRT18	-0.062133
EPCAM	-0.061442
IGDCC4	0.060797
SCGB2A1	-0.059866
TFPI2	-0.059259
EGR3	-0.057299
CDC20	-0.056946
PMAIP1	-0.055201
SERPINA6	-0.053155
PTTG1	-0.052603
SLITRK6	-0.052591
IDO1	-0.052515
COMP	-0.052385
PGR	-0.051745
PIP	-0.050278
FGFBP2	-0.049999
RRM2	-0.049806
CETP	0.049147
COL6A6	0.048862
TNMD	-0.048810
PDZK1	-0.048264
TPRG1	-0.048143
TPSB2	0.048136
SYNGR3	-0.047654
FAM83D	-0.047125
MUCL1	-0.046139
CRISP3	-0.046138
DSP	-0.045633
ISG20	-0.045603
ARHGAP36	-0.045537
TSPAN1	0.045261
DLGAP5	-0.044740
PTGDS	0.044449
S100P	-0.044433
MMRN1	0.044086
CEACAM6	-0.044019
MMP7	-0.043726
CCL8	-0.043501
LAMP3	-0.043378
HMMR	-0.043373
TFF3	-0.043120
TUBB2B	-0.043048
RARRES1	-0.042802
CEP55	-0.042417
ECM1	0.042097
PRC1	-0.041880
UHRF1	-0.041876
CP	-0.041361
APOD	0.040919
TPX2	-0.040511
CHIA	0.040120
ANKRD30A	-0.039925
IL17RB	-0.039745
BUB1B	-0.038805
CCDC3	-0.038621
WIF1	-0.038411
PFKFB3	-0.038250
IRS2	-0.038221
BRINP3	0.038164
COL21A1	0.038015
LBP	-0.037587
TOP2A	-0.037547
RAMP3	-0.037377
EPHX1	0.037273
TRIP13	-0.037200
SAA4	-0.036836
EPYC	-0.036836
CCNB1	-0.036801
NKAIN1	-0.036743
GOLT1A	0.036635
NDP	0.036608
SPINT2	-0.036551
ANXA3	-0.036343
AQP11	0.036250
VTCN1	-0.035896
CENPK	-0.035852
CPXM1	0.035730
PBK	-0.035672
CXCL10	-0.035633
RIIAD1	0.035597
SERPINA5	-0.035545
CES1	-0.035402
PREX1	-0.035111
CCND1	-0.035032
KIF4A	-0.034876
COL11A1	-0.034664
MBOAT1	-0.034572
SLC39A6	-0.034526
SGK3	-0.034478
UBE2C	-0.034401
INPP4B	-0.034182
SHISA2	-0.034144
PLOD2	-0.033985
PRSS23	-0.033925
RMI2	-0.033675
FAM89A	-0.033509
OXTR	-0.033367
CDH1	-0.033244
COLEC12	0.032752
SHCBP1	-0.032730
ASS1	-0.032715
MGP	-0.032618
KIF20A	-0.032584
P2RY2	0.032574
VSIG10L	0.032320
EP300-AS1	0.032107
GPR143	0.032070
FAM60A	-0.031796
GINS1	-0.031634
RBM20	-0.031590
NNMT	-0.031501
C6orf141	-0.031229
MCM3	-0.031139
CTSK	0.031099
ELOVL7	0.031023
E2F8	-0.030912
CCL2	-0.030785
OAS1	-0.030730
ABCG1	0.030658
WNT2	-0.030648
LAMB3	-0.030411
ISG15	-0.030403
FMO2	-0.030145
TFAP2B	-0.030063
IGFBP2	0.029850
PI15	-0.029840
OASL	-0.029786
G0S2	-0.029760
RGS22	-0.029740
GATA3	-0.029691
HBB	0.029549
ZYG11A	-0.029518
PCAT6	0.029435
SCGB3A1	-0.029431
DUSP4	-0.029421
NUSAP1	-0.029392
CX3CL1	-0.029252
PCOLCE2	-0.029218
IGJ	-0.029033
STEAP4	-0.028885
FGD3	-0.028877
TLR1	-0.028831
CYP4X1	-0.028678
KRT19	-0.028628
OSR2	0.028576
KIF15	-0.028406
ZWINT	-0.028369
IRS1	-0.028275
APELA	-0.028268
C6	0.028255
ELF1	-0.027904
BCHE	0.027776
SLC28A3	-0.027624
PNP	-0.027529
TRAM1L1	0.027503
ANGPTL1	0.027492
CRYAB	-0.027376
ZNF750	0.027336
IFI35	-0.027192
SLC23A1	0.027129
CCL18	0.027080
CIDEA	-0.027055
RERGL	0.027006
MREG	-0.026992
ADRA2A	-0.026984
LIPF	-0.026881
IQGAP1	-0.026807
ALYREF	-0.026764
TLR3	-0.026709
CRISPLD1	-0.026668
NUAK1	-0.026625
S100A14	-0.026600
OTOR	0.026585
AREG	-0.026567
IFIT3	-0.026540
ANLN	-0.026491
SLC12A2	-0.026490
MMP10	-0.026346
HES6	0.026254
ELOVL2	-0.026203
CORO1A	-0.026202
IFI44L	-0.026196
S100A7	-0.026130
TK1	-0.026120
SFRP1	-0.025867
STK32B	0.025798
PPP1R1B	0.025795
USP18	-0.025789
AMPH	-0.025728
BPIFB1	-0.025667
FST	-0.025664
CD38	-0.025586
NR2F1	0.025564
MX1	-0.025536
SLC16A6	-0.025513
HSD11B1	-0.025480
NUF2	-0.025471
RPS16P5	-0.025408
MFAP5	-0.025367
APOBEC3B	-0.025361
CYP1A1	-0.025350
BBOX1	-0.025345
C4BPB	0.025334
NUP93	-0.025334
CTGF	-0.025304
IL4I1	-0.025239
HOXB13	0.025216
GBP5	-0.025198
EVL	-0.025120
MAOA	-0.025117
DTL	-0.025092
ERVMER34-1	0.024997
DPP4	0.024994
LMNB2	-0.024943
MAN1C1	0.024817
IFI6	-0.024816
XAF1	-0.024799
BAMBI	-0.024788
HSD3B1	0.024712
C1QTNF7	0.024649
KRT6B	-0.024574
TNFSF4	-0.024537
C1orf226	-0.024477
GALNT7	-0.024449
CLEC3A	0.024443
WARS	-0.024381
LYN	-0.024356
DGAT2	-0.024280
CLIC6	-0.024210
KIAA0101	-0.024155
KIF11	-0.024120
WIPI1	-0.024110
CSTA	0.024103
C10orf10	-0.024079
TLR2	-0.024029
KIAA1107	0.023972
LYPD3	0.023938
MMP3	-0.023918
SAPCD2	-0.023827
TMEM2	-0.023701
CYP4Z2P	0.023698
RSAD2	-0.023641
RTN1	-0.023586
HPGD	0.023518
FCGR1B	-0.023488
SNX10	-0.023425
LMCD1	-0.023424
RPS6KA1	-0.023410
UCHL3	-0.023335
FOXD1	0.023310
ZNF423	0.023184
UTP20	-0.023150
HMGB3	-0.023109
TIMP3	-0.023104
ST6GALNAC1	0.023062
LINC00052	0.023058
RNF128	-0.023044
MYBPC1	-0.022930
CD2	-0.022918
CD83	-0.022917
LINC00959	0.022898
PSCA	0.022878
PIM1	-0.022868
PEG10	-0.022839
ZNF610	0.022807
KRT14	-0.022801
IGSF10	0.022787
MAFF	-0.022735
HERC5	-0.022715
FLT3	0.022680
HPS5	-0.022679
SOX2-OT	0.022664
BCAR4	0.022616
TUSC5	-0.022600
HTR1F	0.022580
SLC7A13	0.022572
QPRT	-0.022501
LRRN3	0.022493
WBSCR17	0.022491
CENPU	-0.022488
RBBP8	-0.022479
TTC9	0.022446
TTK	-0.022444
IGF1R	-0.022427
FAM46B	0.022419
ASPH	-0.022402
SLC25A20	-0.022399
LINC01094	-0.022365
MX2	-0.022345
RASSF10	-0.022343
C1orf116	0.022333
TUBB6	-0.022304
KIF18B	-0.022280
LINC00968	-0.022280
NEXN	-0.022253
CYP4B1	0.022226
FAM198B	-0.022182
MFAP4	0.022114
CSN1S1	0.022068
CFD	-0.022066
RACGAP1	-0.021992
LOC727820	-0.021991
LINC00622	0.021979
TSPAN12	0.021901
S100A9	-0.021898
GNG12	-0.021892
C1orf186	0.021829
FGF1	-0.021815
CMPK2	-0.021800
SLITRK4	0.021797
GLDC	-0.021759
MIA	-0.021674
MAGEA3	-0.021664
INPP5J	0.021661
PCDH19	0.021647
HIST2H2BE	-0.021624
AIFM2	-0.021515
ASH1L-AS1	0.021512
GCOM1	-0.021507
DUSP5	-0.021470
S100G	0.021449
ZNF542P	0.021443
INAFM1	0.021418
KLK11	-0.021413
IGSF6	-0.021402
CEL	0.021396
LOC729680	0.021294
NRCAM	-0.021268
RAB38	-0.021241
LINC01420	0.021235
PPBP	0.021150
TDRKH	0.021137
MGLL	-0.021131
LRRCC1	0.021116
GATA3-AS1	0.021109
RGS17	-0.021031
IGFBP4	-0.021004
ALDOC	-0.020994
CNTN3	-0.020965
GRP	-0.020964
SLC7A5	-0.020941
WFS1	0.020863
RGN	-0.020814
DHX58	-0.020800
GREB1	-0.020786
GLRB	-0.020777
LINC01002	0.020765
CDK1	-0.020759
ABAT	-0.020720
SPP1	-0.020720
HSH2D	-0.020679
PRRG4	-0.020643
EPPK1	-0.020627
MSMB	-0.020580
ESPL1	-0.020567
RDH16	0.020556
RBMS1	-0.020549
SCARA5	0.020513
CHMP4C	-0.020459
HIST1H4C	-0.020446
MON1A	-0.020427
TUBB2A	-0.020383
PNPT1	-0.020372
PLTP	0.020367
PLS1	-0.020356
ECHDC1	-0.020332
ALDH6A1	0.020331
PROM1	-0.020317
ATP8B4	0.020302
STC1	-0.020256
SPON2	0.020254
KIAA1429	0.020248
TMEM216	0.020246
HEBP1	0.020237
COLEC11	0.020234
CHI3L2	0.020195
TMEM47	-0.020151
PDK3	0.020139
CTPS1	-0.020133
FHL2	-0.020127
MUM1L1	-0.020089
HN1	-0.020080
EGFL6	-0.020072
KISS1R	-0.020066
GPR133	0.020020
UBE2S	0.020011
ZNF415	0.020004
ZNF615	0.019995
ZG16B	-0.019993
UBE2T	-0.019984
TPBG	-0.019978
AKR7A3	-0.019946
LOC100131541	-0.019925
CD24	-0.019914
FADD	-0.019858
NELL2	0.019832
CLCA2	0.019810
TPSAB1	0.019802
FOXA1	-0.019800
SMCO4	-0.019792
LPPR4	0.019790
CENPF	-0.019771
GRAMD3	-0.019760
NFKBIZ	-0.019753
PXDN	-0.019749
RHOBTB1	-0.019723
GBP1	-0.019650
GBP2	-0.019648
TCEAL7	0.019622
LINC00893	0.019620
OLFM4	-0.019606
KIF2C	-0.019565
SGMS1	0.019520
PLEKHA8P1	-0.019517
CITED1	-0.019509
AMIGO2	-0.019472
BMP5	0.019430
UNC5D	0.019412
HMCN1	0.019397
LRRTM2	0.019389
CYSLTR1	0.019359
PLP1	0.019345
PVALB	0.019312
AKR1B10	0.019292
PON3	0.019215
LRTOMT	0.019207
PGM5-AS1	0.019189
LOC100287896	0.019174
MID1IP1	0.019168
ZNF818P	0.019156
NFAT5	-0.019138
GPNMB	0.019112
ITGBL1	-0.019085
GZMB	-0.019083
KRT5	-0.019081
NME1	-0.019044
LRRC17	0.019042
ECI2	0.019012
PLIN1	-0.019008
SIAH2	-0.019007
PLD6	-0.018959
IGLV1-40	0.018941
IGLL3P	-0.018926
CA2	-0.018911
RERG	-0.018891
SELP	0.018880
EPSTI1	-0.018876
KLF10	-0.018841
LINC01003	0.018817
IRF1	-0.018776
PCP4	0.018774
COQ6	0.018746
HIST1H2AM	0.018728
IFIT2	-0.018726
C2orf76	0.018707
DNAJC3	-0.018687
RFX6	0.018675
BAZ1A	-0.018672
ODC1	-0.018669
FAM71E1	0.018642
ZNF850	0.018615
SGCE	-0.018614
THBS4	-0.018610
PEAR1	0.018601
ZNF22	-0.018591
SFRP2	0.018577
LRRN1	0.018574
NOD2	-0.018572
FAR2	-0.018550
CEBPA	-0.018544
DDIT4	-0.018531
NEUROD1	0.018515
RAB25	-0.018515
SPANXB1	-0.018513
KPNA2	-0.018486
RIMS1	0.018485
AZGP1	-0.018485
GCH1	-0.018464
CENPA	-0.018445
TBC1D4	-0.018438
KBTBD8	-0.018436
EZH2	-0.018409
ELMO3	0.018390