!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!drug_name	Tretinoin
!smiles	CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC(=O)O)C)C
!drugbank_id	DB00755
!pubchem_cid	444795
!cell_type	NB4 APL 9 acute promyelocytic leukemia cells -  (TG2-knockdown) 72 Hours
!organism	human
!end_metadata
CYTL1	-0.061286
BPI	0.059225
TGM2	0.055103
ALOX5AP	0.052573
VIM	-0.052311
SNORD41	-0.049171
SELL	0.048689
FGR	0.048534
MIR142	-0.045423
CCL24	0.043849
LHFP	-0.043617
EBF3	-0.042843
MMP9	-0.042002
DHRS3	0.041972
SNORD14E	-0.041654
PADI2	0.041564
CYP1B1	-0.040751
SNORD14C	-0.040413
SNORA23	-0.039629
PSMB8	0.038855
DEFA4	0.038799
SNORA71D	-0.038140
MAP7D3	-0.038111
PSMB9	0.037832
LYZ	-0.037593
PRAM1	0.037570
CD52	0.036008
HDC	-0.035701
PRG2	-0.035383
FBP1	0.035192
SNORA38B	-0.034619
NQO1	-0.034442
GNG2	0.034047
CD300A	0.032666
AAED1	-0.032370
SNORD4A	-0.032240
SNORD4B	-0.032027
GPR97	0.031913
ASS1	-0.031710
PADI4	0.031645
MT1F	-0.031429
CDC42EP3	-0.031078
CTSG	-0.030928
SNORD13	-0.030896
SLC2A5	0.030758
SNORD115-44	0.030736
LAMB3	0.030518
TBL1X	-0.030469
SNORD115-24	0.030332
SERPINB1	0.030301
FAM101B	-0.030248
LRRC37B	-0.030180
FCGR2A	-0.030137
PLCB2	0.030094
ITGB7	0.029944
S100A8	0.029875
RCSD1	0.029737
ZNF675	-0.029650
MORN2	-0.029504
ICAM1	0.029383
C1orf186	-0.029378
PSG8	0.029337
DTD2	-0.029293
RBP4	-0.029289
PEA15	-0.029139
SNORA24	-0.029099
MS4A3	-0.028927
ATP5G1	-0.028578
LRG1	0.028508
IL17RA	-0.028270
IRF1	0.028061
CST7	-0.027809
ECRP	-0.027755
OCR1	-0.027747
PAPD5	-0.027733
RNF125	-0.027576
RNF130	-0.027543
SNORA76A	-0.027443
TNFAIP2	0.027377
DUSP10	-0.027348
CHAC2	-0.027264
FAM46C	-0.027190
MIR202	0.027190
CES1	0.027161
BCL11A	-0.027123
ZNF737	-0.027081
SLC7A11	-0.027060
SNORA45A	-0.026929
NOL7	-0.026900
UBR3	-0.026853
CHST11	-0.026853
COX5B	-0.026769
CCNE2	-0.026767
RNU5D-1	0.026725
FFAR2	0.026685
SNORD58A	-0.026558
MT2A	-0.026362
RPP40	-0.026349
CTSH	-0.026344
VTRNA1-3	-0.026323
NCALD	-0.026252
LGALS1	-0.026225
GINS2	-0.026202
LOC100134822	-0.026040
TNFSF10	-0.026025
PFKFB4	0.026019
ASB2	0.026015
MCEMP1	0.025988
PKN1	0.025967
ANKRD12	-0.025874
FLJ36840	-0.025846
TNF	-0.025840
TULP3	-0.025839
TMEM173	0.025781
TAS2R50	-0.025762
BCL2	-0.025700
RALGAPA1	-0.025555
SLA	0.025507
SLC44A1	0.025443
TMEM254	-0.025441
SACS	-0.025437
RPP38	-0.025416
AMICA1	0.025376
USP17L6P	0.025362
PCGF6	-0.025290
CCL2	0.025103
AHNAK	-0.025077
GNG4	-0.025012
TMEM261	-0.024791
C10orf54	0.024755
RSU1	-0.024646
SNORD115-21	0.024641
NCF2	0.024640
CA8	-0.024606
NSMF	-0.024583
MINOS1	0.024566
SSBP2	-0.024514
NT5DC2	-0.024499
KCNH4	0.024490
MDK	0.024393
MMP2	-0.024361
TAS2R14	-0.024284
SERPINB8	-0.024279
ALAS1	0.024251
CRTC3	-0.024237
MRPS11	-0.024216
CRISP3	0.024182
SNORD42A	-0.024090
FLJ45950	0.024083
ZEB2	-0.023946
PHACTR4	-0.023942
C15orf41	-0.023914
SASS6	-0.023908
JPX	-0.023865
SLC39A14	-0.023753
SDC2	-0.023696
FAM43A	-0.023677
EBAG9	-0.023669
SGOL1	-0.023611
DCAF17	-0.023610
HAUS1	-0.023600
GEMIN5	-0.023576
SMOX	0.023414
FCHSD2	-0.023350
COX16	-0.023327
C12orf75	-0.023300
POP4	-0.023286
MCAM	-0.023227
LFNG	0.023177
ATG2B	-0.023171
MIR181B1	-0.023167
SNORA20	-0.023147
DDIAS	-0.023128
RNU5A-1	-0.023042
DUSP6	0.023008
OSBPL11	-0.022989
TRAM2	-0.022968
ZRANB3	-0.022967
MIR302B	0.022959
ASIC1	-0.022871
DCUN1D4	-0.022752
ALMS1	-0.022715
IFNA10	0.022710
PARP14	0.022682
C11orf24	-0.022676
TMTC2	-0.022637
MRPL40	-0.022613
PVRL1	0.022612
SNORA68	-0.022598
CA2	-0.022564
ARAP1	0.022492
HK3	0.022486
SNORD45A	-0.022458
MT1X	-0.022451
ADI1	-0.022387
CXCR2	0.022373
TMEM160	-0.022371
ASGR2	-0.022321
ZNF138	-0.022311
ZNF593	-0.022300
DPH6	-0.022276
MIR15A	-0.022235
MIR125B1	0.022201
CLOCK	-0.022194
CD38	0.022115
TAF9B	-0.022088
SNORD36B	-0.022083
LRRC8C	-0.022020
ZNF280C	-0.021999
RET	-0.021981
SLC10A5	-0.021978
C1RL	0.021972
NARS2	-0.021966
DNMT3B	-0.021953
MYO1B	-0.021952
ZBTB8OS	-0.021934
PIK3C2A	-0.021893
INSIG2	0.021861
SCRN3	-0.021832
AAK1	-0.021830
ATP1B1	-0.021789
WT1-AS	-0.021775
KIAA1147	-0.021775
CMSS1	-0.021712
ESCO2	-0.021689
OGFR	0.021621
COTL1	0.021562
STRADB	-0.021545
FAM118B	-0.021531
DDIT4	0.021513
BHLHE40	0.021512
HIP1	-0.021510
EPAS1	0.021471
GPR160	0.021469
MRC2	-0.021446
NAT8L	0.021431
ZNF566	-0.021427
TMEM116	-0.021404
HEBP2	-0.021377
RPAP2	-0.021358
SNAP29	-0.021340
TAF4B	-0.021338
FNTB	-0.021331
RNU4ATAC	-0.021319
LINC00266-1	-0.021306
CD44	-0.021286
RBBP9	-0.021272
FSCN1	-0.021256
STS	-0.021232
SLC20A1	-0.021207
VAV2	-0.021194
STAMBPL1	-0.021180
CHIC2	-0.021120
SNORD82	-0.021081
MIR98	0.021069
BEND6	-0.021046
CEP170	-0.021044
CLEC5A	-0.021036
ASB8	-0.021035
CEP83	-0.021031
STAB1	-0.021028
ZBTB16	-0.021010
ANXA2	-0.020972
TAF2	-0.020969
GPR85	-0.020963
PTPLB	-0.020936
ERAP2	0.020916
F3	-0.020876
THBS1	-0.020866
RAB38	-0.020865
PDP1	-0.020831
HLA-B	0.020826
KIAA1551	-0.020824
FBXO16	-0.020816
VLDLR	0.020763
SNORD32A	-0.020747
IFT74	-0.020712
MNAT1	-0.020700
HOMER1	-0.020641
EMR3	0.020639
OSER1	-0.020635
TGIF1	-0.020622
SNORD116-22	0.020607
FLOT1	0.020553
ELOVL3	-0.020543
ABCB10	-0.020518
CTSW	-0.020513
SNORD15A	-0.020448
NDUFB6	-0.020437
HS6ST1	-0.020436
SLC31A1	-0.020389
MGC57346	-0.020380
DTYMK	-0.020371
ZNF480	-0.020367
DOCK10	-0.020316
EPX	-0.020313
CLN5	-0.020297
C15orf61	-0.020293
SNORA74A	-0.020251
E2F5	-0.020230
CKAP2L	-0.020212
MERTK	0.020197
STARD4	0.020194
MTA3	-0.020171
ANPEP	-0.020167
USP3	-0.020166
HLA-C	0.020150
PSMB6	-0.020118
SNORD116-13	0.020116
INPP5A	-0.020104
SPARC	-0.020088
LOC441268	0.020081
MIR100	0.020080
ROPN1L	-0.020080
MSL3P1	-0.020073
TMEM156	0.020069
KMT2C	-0.020048
ERRFI1	-0.020021
MTUS1	-0.020018
CBLL1	-0.020015
SNORD115-31	0.020004
ZNF398	-0.019985
MBIP	-0.019981
POP7	-0.019941
DTWD1	-0.019935
MIR186	-0.019906
EMR2	-0.019886
P2RY2	-0.019865
RPGRIP1L	-0.019863
LMLN	-0.019831
MIR10B	0.019821
MGST1	-0.019816
MND1	-0.019808
SNORD113-4	0.019804
FAM117B	-0.019746
HIST1H4D	-0.019746
INTS4	-0.019735
PACRGL	-0.019733
HEXB	-0.019732
FAM217B	-0.019725
SPRY4	-0.019695
ADA	0.019693
PGBD5	-0.019683
FKBP2	0.019675
NDRG1	0.019672
ATXN7L1	-0.019667
NFAT5	-0.019665
PARGP1	-0.019640
PRDX5	0.019617
NAF1	-0.019609
BBS10	-0.019602
ATMIN	-0.019596
ABI2	-0.019589
SNORA56	-0.019585
SNORD115-15	0.019548
ZNF473	-0.019522
PDXDC2P	-0.019493
PDCD4	0.019493
IFI35	0.019484
DCP1B	-0.019479
TNFRSF21	-0.019445
FASTKD3	-0.019425
BEND3	-0.019410
PIK3R4	-0.019398
FAM210A	-0.019396
ST3GAL6	-0.019366
DCP1A	-0.019362
EIF1AD	-0.019353
SYT11	-0.019347
RDH10	-0.019342
PTAR1	-0.019342
NCS1	-0.019332
SNORD114-2	0.019324
TMEM177	-0.019320
PCBP3	-0.019303
IQGAP2	-0.019291
RPPH1	0.019276
KIAA2026	-0.019265
CD58	-0.019254
SNORD116-16	0.019237
CCDC112	-0.019228
MGST2	0.019219
ZNF706	-0.019192
CTSS	0.019177
GAB2	-0.019168
PCMT1	-0.019165
FARS2	-0.019164
STIL	-0.019163
ZNF429	-0.019160
AFF2	-0.019158
CSPP1	-0.019147
ERP27	-0.019085
SETMAR	-0.019041
C12orf4	-0.019040
SNX2	-0.019022
VTRNA1-1	-0.018974
PTGER4	-0.018947
PTPRE	-0.018936
UFSP2	-0.018914
CYB5D1	-0.018898
B4GALT6	-0.018895
STK17B	-0.018882
TMA7	-0.018875
RASAL2	-0.018865
HEBP1	-0.018835
CCDC66	-0.018820
TUBG1	-0.018819
NAGA	0.018808
LSM5	-0.018794
CTNNAL1	-0.018776
HSPB1	-0.018776
MIR182	0.018746
ZNF271	-0.018744
HLA-A	0.018738
LOC100129033	-0.018730
MRPS2	-0.018729
ETV6	-0.018712
SLC1A4	-0.018703
PSD3	-0.018702
DCAKD	-0.018700
REPS1	-0.018670
BID	-0.018663
GINM1	-0.018663
FAM13B	-0.018638
NUP214	-0.018610
GM2A	0.018590
GDAP2	-0.018589
EXOC6B	-0.018555
ABHD5	-0.018544
ASRGL1	0.018543
ROR2	0.018503
BRPF1	-0.018495
APOO	-0.018484
HCLS1	0.018473
POU2F1	-0.018444
RARRES3	0.018432
WT1	-0.018427
SLPI	-0.018420
HERC5	-0.018410
USP13	-0.018402
LIPK	0.018400
HIST2H4A	-0.018390
HIST2H4B	-0.018390
CEBPE	0.018384
DDHD1	-0.018378
RYBP	-0.018374
ECD	-0.018357
TNIK	-0.018345
FFAR4	-0.018324
CDC34	-0.018319
CAPN2	-0.018298
HVCN1	-0.018295
SNORA4	-0.018262
ARL3	-0.018253
PPP1R12B	-0.018252
C1orf112	-0.018242
CSPG4P5	-0.018241
TAS2R4	-0.018216
PSENEN	-0.018212
UBXN8	-0.018197
ALG13	-0.018193
RRM2B	-0.018189
ZNF597	-0.018181
STX2	-0.018179
CFHR2	0.018177
CENPU	-0.018173
BRCA2	-0.018163
DIAPH2	-0.018159
CCR1	0.018139
UFC1	-0.018133
LOC642947	-0.018090
SNORD57	-0.018087
PPP1R12A	-0.018086
ACSS2	0.018081
RNF26	-0.018077
HIST1H3A	-0.018077
AKR1B1	-0.018067
TULP4	-0.018063
NUDT5	-0.018037
CYP2R1	-0.018020
MIR30C1	0.018002
NPM3	-0.017983
GTF2H1	-0.017976
NDUFA13	0.017964
KPNA3	-0.017941
CPSF4L	0.017940
KANSL1L	-0.017931
HLA-G	0.017916
DTWD2	-0.017910
NPY4R	0.017908
RC3H1	-0.017901
SND1-IT1	-0.017899
ZNF146	-0.017879
SLCO4C1	0.017873
SIPA1L1	-0.017854
SNORD51	-0.017827
TRAK2	-0.017805
CYB5A	-0.017789
DDX52	-0.017787
NFE2L3	-0.017786