!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!ligand_name	estradiol
!ligand_id	CHEBI:23965
!cell_type	MCF-7 cells
!organism	human
!end_metadata
TFF1	0.194611
TPD52L1	0.162327
LXN	-0.140864
NQO1	-0.133499
CYP1A1	-0.130861
CCND1	0.125167
BASP1	-0.120348
HSPB1	0.098059
RLN2	0.097755
NME1	0.095645
HSPA8	0.093552
CA2	0.092959
AGR3	0.089478
MIR21	-0.088657
RAN	0.086078
RRS1	0.085336
CD24	-0.084138
FTH1P5	-0.082952
RAB31	0.080563
MREG	0.079170
NOP58	0.077092
DDX21	0.076592
TMEM64	0.075520
ANXA2	-0.074987
HIF1A	0.074079
PCNA	0.073598
IRF2BPL	-0.073422
PLOD2	0.072286
XBP1	0.071887
KRT19	0.071242
PKIB	0.070465
CA12	0.067815
TUBA1A	-0.066702
DKC1	0.066582
PRMT6	0.066169
HNRNPAB	0.065290
STC2	0.065082
NRIP1	0.063790
AGR2	0.063574
MAL2	-0.063439
BCAS3	-0.063436
DDIT4	-0.063350
MRPS23	0.061761
PLK2	-0.060004
UHRF1	0.059725
ABAT	0.058733
PCP4	0.057840
PPIF	0.057743
SLC7A5	0.056860
UGCG	0.053141
TMSB10	-0.052642
DYNLT3	0.052624
TBCA	0.052143
PUS7	0.051844
CCT2	0.051639
ISG15	0.051638
CELSR2	0.051488
UBC	-0.051241
CYP1B1	-0.051205
MCM2	0.050929
SRSF2	0.050642
ANP32B	0.050596
BOD1	0.050057
CKS2	0.049978
MYL12B	-0.049694
SLC25A5	0.049590
PNRC1	-0.049169
PTMA	0.049001
SFXN2	0.048856
RPF2	0.048818
ND2	0.048640
NHP2	0.048447
SET	0.048421
ALYREF	0.048140
NPY1R	0.048077
RND3	-0.047872
FTH1	-0.047688
SRP14	-0.047413
ZDHHC7	-0.047303
PDLIM1	-0.047085
NOP56	0.046572
ELF1	0.046448
CXXC5	0.045476
TRIM16	-0.045453
CAV1	0.045250
SRSF7	0.045101
EMP2	0.044886
SLC35A1	-0.044545
TOP1	0.044519
C1QBP	0.044091
HMOX1	-0.043963
TFPI	-0.043782
EIF4A1	0.043618
ID3	-0.043238
TFRC	0.043189
PLEKHF2	-0.043062
ZNF217	-0.043015
PAPSS2	0.042973
HILPDA	-0.042903
YWHAZ	-0.042861
TMEM164	0.042758
TPBG	0.042746
ISOC1	0.042735
IARS	0.042601
EGR3	0.042362
S100P	-0.042331
RMI2	0.042299
RPS3	0.042279
S100A10	-0.042211
RPL4	0.041899
SMS	0.041750
AHSA1	0.041665
TST	0.041612
ARPC1B	-0.041507
DBI	-0.041269
SH3BGRL	-0.041227
KYNU	-0.041161
TAX1BP3	-0.040827
LDHA	0.040792
MCM3	0.040714
TUFT1	-0.040704
TMBIM6	-0.040257
MLPH	0.039565
MTHFD1	0.039527
SGK3	0.039472
SLC9A3R1	0.039415
DCTPP1	0.039402
HSP90AB1	0.039052
RPL7L1	0.037676
GGCT	0.037653
LPCAT1	0.037432
SRP9	-0.037310
MCM6	0.037278
CBWD1	0.037014
WISP2	0.036967
MCM7	0.036671
COX8A	-0.036582
H2AFZ	0.036568
PRSS23	0.036393
GARS	0.036339
TMEM150C	-0.036336
COX7A2	-0.036239
HSPA1A	-0.036229
GREB1	0.035876
CLIC3	-0.035807
BAMBI	-0.035680
CDH1	0.035570
SEMA3C	0.035482
SYTL5	0.035440
RPL9	0.035019
GINS1	0.034796
FEN1	0.034520
TOMM5	0.034502
NBPF10	0.034497
CSRP1	-0.034410
VAMP8	-0.034404
ZNF367	0.034253
ACTG1	-0.034230
CD55	-0.034148
HSPD1	0.034036
GSTM3	-0.034026
FOXC1	0.033923
TMED8	0.033827
S100A13	-0.033747
MYOF	0.033724
UNG	0.033636
GALNT4	0.033598
CMC2	0.033402
NT5C3A	0.033356
GLA	0.033294
NCL	0.033162
PHLDA1	0.032886
PMAIP1	0.032814
NPM1	0.032782
MGST1	-0.032720
SDCBP	-0.032490
MYL12A	-0.032444
KLF10	0.032362
ERMP1	-0.032353
SNHG1	0.032301
MRPL14	0.032133
ITGAV	-0.032121
CDK4	0.031935
DBF4	0.031880
NOLC1	0.031843
ACTB	-0.031660
CAP1	-0.031556
BRIP1	0.031490
HIST1H4C	0.031352
S100A16	-0.031341
XPOT	0.031306
SRSF1	0.031262
ABCG2	-0.031206
ANXA2P2	-0.031199
ILF2	0.030904
MRPL36	0.030850
MRPL15	0.030762
RAB9A	-0.030680
CCNG1	-0.030610
COA4	0.030571
MICB	0.030545
FBL	0.030544
EFNA1	-0.030103
CSTA	-0.029951
C6orf211	0.029892
SEMA4C	-0.029867
LMNB1	0.029781
FABP5	0.029759
RPSA	0.029552
MRPL3	0.029470
PMEPA1	-0.029465
RASGRP1	0.029344
HSP90AA1	0.029309
SLC38A1	-0.029138
MPHOSPH10	0.029108
IDH1	-0.029014
NRAS	-0.029010
PODXL	0.028986
DUT	0.028981
GMNN	0.028861
SLIRP	0.028857
MYO1B	-0.028854
S100A11	-0.028832
UBE2S	0.028806
GRB14	-0.028701
FTL	-0.028494
JAK1	0.028439
ETFA	-0.028226
YBX1	0.028155
AMOTL2	-0.028133
ATAD2	0.028099
DNMT1	0.027977
AMD1	0.027773
EIF2S1	0.027754
HIST1H2AC	-0.027719
GTF3A	0.027696
UBL3	-0.027614
KLF4	0.027601
SIGLEC15	0.027511
CLIC1	-0.027434
NUP35	0.027320
PTRH2	0.027266
HSPE1	0.027094
TRA2B	0.027067
SLBP	0.027055
PPT1	-0.027013
TALDO1	-0.027013
GFRA1	0.026805
KPNA2	0.026786
PNPT1	0.026774
ID2	-0.026729
TKT	-0.026718
SLC38A2	0.026668
DSTN	-0.026665
NTN4	-0.026642
YPEL5	-0.026586
ANXA5	-0.026567
TIPARP	0.026503
SLC39A6	0.026447
C17orf58	0.026226
ARPC3	-0.026217
HAUS1	0.026183
DYNC1I2	-0.026179
PIK3R1	0.026160
RPS25	0.025951
ATRAID	-0.025876
GPD1L	0.025790
SNRPG	0.025600
LDOC1	-0.025539
CCDC47	0.025537
LYSMD2	0.025508
DEPTOR	0.025479
FAM110C	-0.025359
COX6C	0.025278
SNORD104	0.025252
NIP7	0.025238
RAD51C	0.025219
SRP19	0.025175
STARD7	0.025145
UBA2	0.024877
MKNK2	-0.024856
SLC25A24	0.024829
REEP5	-0.024698
NOL11	0.024685
CYC1	0.024679
RPS26	0.024581
BRI3BP	0.024505
ST8SIA4	-0.024485
S1PR3	-0.024462
NT5C2	0.024452
TP53INP1	-0.024358
ID1	-0.024337
NAA50	0.024297
SETD1B	0.024225
OTUD6B	0.024189
ME1	-0.024112
CEBPB	0.024015
UTP18	0.023912
SSB	0.023862
RAMP3	0.023852
FXYD3	-0.023805
SAC3D1	0.023731
RPL22L1	0.023718
CCNG2	-0.023610
PRKAR1A	-0.023598
NIFK	0.023582
CDH3	-0.023543
AHRR	-0.023498
EEF1B2	0.023455
RHOBTB3	0.023445
SUCO	0.023427
SULF2	0.023381
CTPS1	0.023364
RAB27B	-0.023346
USP1	0.023304
PGAM1	0.023234
ANXA3	-0.023227
CIRH1A	0.023212
MYC	0.023192
CCT6A	0.023189
ZNF703	0.023163
PNPLA8	-0.023117
OAT	-0.023082
NGFRAP1	-0.023051
LYAR	0.022856
MYBL1	0.022852
NDUFAB1	0.022843
TCERG1	0.022826
FKBP4	0.022820
UBB	-0.022763
GABARAPL2	-0.022751
HAT1	0.022731
SCCPDH	-0.022652
NCOA3	-0.022624
PAICS	0.022610
MRFAP1	0.022485
CMSS1	0.022462
HIST2H2BE	-0.022460
CBX3	0.022439
MAD2L1	0.022372
CCT7	0.022312
UGDH	0.022305
GNG10	-0.022265
LGALS1	-0.022207
CALCR	0.022138
KARS	0.022128
POLE3	0.022082
SLC16A6	0.022027
BTG1	-0.022002
SERBP1	0.021942
MORF4L1	-0.021911
RAB13	-0.021809
WWP1	0.021804
AKAP1	0.021722
FREM2	0.021713
RPL35	0.021604
OSR2	-0.021601
TLE1	-0.021594
METRNL	-0.021568
STARD10	0.021556
GPR137B	-0.021540
SNHG16	0.021486
TUBB4B	0.021455
UBE2T	0.021431
MRPL32	0.021423
EPRS	0.021405
PFDN2	0.021397
EPS8	-0.021348
MALAT1	-0.021285
SYNCRIP	0.021257
KIAA1522	-0.021250
PABPC1	-0.021244
SNRPD1	0.021216
FAM214A	-0.021179
ATOX1	-0.021014
RPP40	0.020977
CIB1	-0.020890
SNRPB	0.020871
CORO1B	-0.020865
ACSL3	-0.020832
KIAA0101	0.020783
MED13L	0.020760
TIPIN	0.020749
MYB	0.020723
TXNRD1	-0.020703
ZC3H15	0.020657
PPIC	-0.020649
HDDC2	0.020648
AIM1	-0.020615
CBX6	-0.020611
LITAF	-0.020529
MCEE	0.020527
LOC729680	0.020509
NXT1	0.020465
RRP15	0.020458
DDX24	0.020445
DEK	0.020436
RXRA	-0.020434
GLRX2	0.020383
CCT3	0.020375
C3orf14	-0.020351
WDR12	0.020280
HEBP2	-0.020267
PTGES3	0.020234
FAM216A	0.020219
IFT20	-0.020206
ESRP1	-0.020194
ORC6	0.020187
CHCHD2	0.020163
MAT2A	0.020136
SRSF5	-0.020112
SERPINA3	0.020101
SLC22A5	0.020077
RFC4	0.020071
CDKN2B	-0.020057
B3GALNT1	0.020037
UQCRQ	-0.020025
RPS21	0.020002
DDX39A	0.019974
MAGED1	-0.019944
RPL34	0.019929
GAR1	0.019921
NOTCH2NL	0.019911
BRI3	-0.019899
CD63	-0.019895
RPL27	0.019884
MBOAT1	0.019869
PSAP	-0.019854
TOPBP1	0.019846
SERINC1	-0.019828
CUTA	-0.019744
RPL26	-0.019698
C6orf141	0.019696
HIST1H2BD	-0.019696
EIF1AX	0.019682
SGK1	0.019656
WDR3	0.019648
HIGD1A	0.019622
SRM	0.019610
CDKN1B	-0.019565
KRT80	-0.019555
ENOPH1	0.019524
PSMG1	0.019496
NUP107	0.019470
ZNF185	0.019428
SMIM15	0.019384
RPL8	0.019361
PFDN5	-0.019274
EPAS1	-0.019271
PIGP	-0.019192
RPS6KB1	0.019168
PTP4A2	0.019166
ARF6	0.019165
PTRHD1	-0.019148
GABARAP	-0.019119
ERP29	-0.019092
MSX2	-0.019079
SNHG15	0.019064
CCDC86	0.019050
NOP16	0.019025
PTPLB	0.019004
RAB11A	-0.019004
SLC24A3	0.018974
SLC2A10	-0.018856
GINS2	0.018810
PSMA7	0.018793
EEF1G	-0.018792
HS3ST3A1	0.018792
KPNB1	0.018786
ZMYND19	0.018779
TUBB2A	-0.018714
NDUFB5	-0.018672
CKS1B	0.018671
TUBA1B	0.018641
UCP2	-0.018634
NR2F2	0.018614
IL1R1	-0.018594
CCNI	-0.018593
DNAJA1	0.018590
LASP1	-0.018490
UCK2	0.018486
FAM83B	-0.018451
ITM2B	-0.018449
GTPBP4	0.018408
UQCRFS1	0.018399
SAT1	-0.018396
SERF2	-0.018364
LYPD6B	-0.018339
TOMM20	0.018269
DAP3	0.018243
IMP4	0.018172
SNRPA1	0.018159
E2F6	0.018051
PRIM1	0.018037
FAM102A	0.018019
CCT5	0.018000
ALDH1A3	-0.017979
NDUFB11	-0.017908
CDV3	0.017898
PGR	0.017888