!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	4-Hydroxynonenal
!smiles	CCCCCC(C=CC=O)O
!pubchem_cid	5283344
!cell_type	RKO colorectal carcinoma cell line (24 Hours after exposure to 5uM)
!organism	human
!end_metadata
MT1HL1	-0.164910
RPL34	0.150187
SOD1	-0.121975
MT2A	-0.120532
MT1H	-0.116924
ANP32B	-0.096539
ATF4	-0.095363
ANXA2P2	-0.090312
RPL32	-0.089975
NGFRAP1	0.088298
RPL36	-0.087315
UQCRQ	-0.086513
SNHG5	-0.086467
RPLP0	-0.086314
RPL19	-0.080438
ATP5B	0.072571
PABPC3	-0.071402
UBE2S	-0.070933
NEDD8	0.070599
ATP1B3	-0.069090
TSPO	-0.066271
NDUFA4	-0.065904
S100A6	-0.065449
LSM7	-0.065281
RPS15	-0.064891
TXN	0.062893
PFN1	-0.062023
ODC1	0.061445
MT1X	-0.060623
RPL13A	-0.058009
CEBPB	-0.057425
NACAP1	0.057327
IER2	-0.056952
RAN	-0.056373
PTGES3	0.054779
RPS3	0.054510
MRPL10	-0.054316
STIP1	0.054133
TCEB2	-0.054005
ATP6V0B	0.053808
HMGN2	0.053238
MRPL33	-0.052630
FUCA2	0.052488
TMEM123	0.052303
RPL27	-0.052135
GARS	-0.052010
CDC37	0.051721
DDX5	0.051693
RPL14	0.051681
IARS	0.050940
SSR4	-0.050849
RPL4	0.050816
PRDX1	0.050644
ERH	-0.050482
DYNLL1	-0.050328
ISOC1	-0.049546
EEF1B2	0.049339
ACOT9	-0.049232
FXYD5	-0.049026
CCNG1	-0.049023
KPNA2	0.048778
ATP5D	-0.048430
DDOST	-0.047956
RPS2	-0.047677
TMA7	-0.047615
COX8A	-0.047414
GPX1	-0.047211
LAPTM4A	0.047202
PSMG2	-0.046949
MYC	-0.046856
NEAT1	0.046711
RPL8	-0.046667
NCOA4	0.046611
HSPA5	0.046482
EIF1	-0.046348
SFN	0.046307
S100A2	0.046213
FHL2	-0.045691
CYR61	-0.045388
PRDX6	0.045277
H2AFZ	0.045268
RPS10	-0.045170
WHAMMP2	-0.044910
PLOD3	-0.044655
ZWINT	0.044645
KARS	0.044152
PSMB3	-0.043990
GDI2	0.043689
GNG5	-0.043671
CUTA	-0.043308
RPS21	-0.043299
TNFRSF12A	-0.043069
NQO1	0.042970
NDUFB9	-0.042839
RPL26L1	-0.042263
CFL1	-0.042219
SMNDC1	-0.042137
SUMO4	0.041828
NAE1	0.041720
BAG3	0.041399
FTL	-0.041383
HMGA1	-0.041166
RPS13	-0.041018
CSNK2B	-0.040729
RPL9	-0.040602
LDHB	-0.040550
PPP2R1A	0.039867
CCT3	0.039635
SLC25A3	-0.039380
NDUFA1	-0.039380
BAG6	-0.039179
MT1F	-0.039163
PSMD8	-0.038989
PSMA4	-0.038982
SF3B6	0.038959
RPL18	-0.038818
TUBA4A	0.038612
SSNA1	0.038291
NAA50	0.038084
POLR2G	-0.037807
LSM1	0.037676
RPS5	-0.037425
EIF2S2	-0.037166
MRPL37	-0.037161
ABRACL	0.037135
RPL41	-0.037019
BMI1	0.037008
GLTSCR2	-0.036734
SSR2	0.036687
GAPDH	-0.036682
MESDC1	-0.036417
RPS8	-0.036352
APOBEC3B	-0.036321
IL32	-0.036138
CS	-0.035748
YWHAZ	0.035645
AP2S1	-0.035635
SUMO2	0.035575
PSMA1	-0.035440
HSPA8	0.035405
BZW2	-0.035183
PTTG1	-0.035160
RPL10A	0.035082
RPS3A	-0.034974
CAMLG	0.034948
NSA2	0.034661
CFAP20	-0.034539
ATP5J	0.034287
PPP1CC	-0.034203
DARS	-0.034193
DEK	-0.034183
DDX39A	0.034113
NPIPA1	0.033989
COASY	0.033785
MCM7	-0.033737
NME1	0.033736
GOT2	-0.033704
SLC35B1	-0.033551
RHOA	-0.033319
H2AFY2	0.033275
CALM2	-0.033203
PSMC5	0.033178
GNB2L1	-0.033164
PA2G4	0.033155
EBPL	0.032952
FKBP11	0.032949
FAM83D	0.032947
APEX1	0.032790
ACTG1	-0.032705
SNRPD1	0.032546
HNRNPK	0.032420
GPI	-0.032402
SLC39A1	-0.032376
CHCHD1	0.031981
MRPL3	-0.031907
HDAC1	-0.031848
PTMA	-0.031817
HAUS1	-0.031687
EPB41L4A-AS1	0.031663
BCL2A1	-0.031492
RPLP2	-0.031438
KANSL1	-0.031426
SLIRP	0.030859
RPL36AL	0.030762
SLC38A2	-0.030700
HSP90AB1	-0.030661
SLC38A5	0.030434
TPX2	-0.030407
CCT2	-0.030349
RPL23A	-0.030279
RPL39	-0.029964
PGAM1	0.029931
RPL30	-0.029930
YWHAQ	-0.029866
FBL	0.029752
NCKAP1	0.029727
GLRX	-0.029696
RPL3	-0.029608
THOC1	-0.029468
ITPR3	-0.029378
OAZ1	0.029252
UQCRH	0.029115
TMED2	0.029087
GNL3	0.029011
RAB1B	-0.028984
EIF3E	-0.028920
ALDH9A1	-0.028879
SMIM15	-0.028853
RPL35A	-0.028798
CCDC28A	-0.028768
AP1S1	-0.028721
RPS19	-0.028711
YWHAB	-0.028704
LONP1	-0.028672
UPP1	0.028503
ATP5F1	-0.028441
VPS28	-0.028435
BANF1	-0.028400
SRP14	0.028358
PPA1	0.028324
ZCRB1	-0.028318
NT5C3B	0.028184
IFI27L2	-0.028161
S100A11	-0.028094
SET	-0.028086
SNRPA	-0.028060
EPRS	-0.028060
TMEM258	-0.027947
C6orf48	0.027937
RPL26	-0.027858
NDUFAF2	0.027827
UBC	-0.027785
ALDOA	-0.027741
CDK2AP1	-0.027597
TUBB	-0.027526
TRMT5	0.027443
CTSL	0.027400
HERPUD1	-0.027200
NMB	-0.027198
PARG	-0.027190
AARS	-0.026828
OCIAD2	0.026808
TMBIM1	0.026807
AMD1	0.026804
TRAPPC1	-0.026714
NAP1L1	0.026639
KIAA0101	-0.026627
PNRC1	0.026576
RPS29	-0.026538
RARS	0.026220
PCK2	-0.026205
RAP1B	-0.026178
EPHA2	-0.026077
PHF5A	-0.026069
HDGF	-0.026036
ACO1	0.026027
ACTB	-0.025974
PSENEN	-0.025845
RNASEK	-0.025843
TALDO1	0.025812
USP32P2	0.025772
PHC2	-0.025689
GSR	0.025667
VDAC2	0.025653
BMS1	-0.025566
SHCBP1	0.025553
NDUFV3	-0.025528
BSG	-0.025506
WDR12	-0.025471
CPSF7	-0.025374
NMU	-0.025323
NDUFV2	-0.025316
XPOT	-0.025299
CLPP	-0.025294
POLB	-0.025081
SLC26A11	0.025076
IER3IP1	-0.025031
COX1	0.025009
NDUFA9	-0.024955
RPL12	-0.024863
PUS7	0.024849
SNRPD2	-0.024843
LSM14A	0.024820
TOP2B	-0.024812
CCNH	-0.024799
OR7E104P	0.024790
HSPE1	0.024785
SLC4A2	-0.024783
CD81	-0.024770
CCT5	-0.024739
WDR83OS	0.024713
CTR9	0.024701
FTH1P5	0.024678
XPC	0.024614
UFD1L	0.024556
CCDC51	0.024534
MRPL24	0.024403
NARS	-0.024380
SEPN1	-0.024352
PSMB7	0.024250
TXNDC12	-0.024239
MAP2K1	0.024182
CETN3	-0.024169
KLF10	-0.024149
FOSL1	-0.024129
CHTF8	-0.024111
SURF4	0.024104
COX2	-0.024050
RPS20	-0.024040
EIF3H	-0.023985
MYL12B	-0.023838
FUBP3	0.023773
TSEN34	-0.023754
NCAPD3	-0.023741
SEC61B	0.023711
MRPL13	-0.023657
CECR5	0.023653
NDUFC2	0.023637
LAMTOR1	-0.023557
HIATL2	0.023525
IFNGR2	0.023505
ETF1	-0.023482
SRSF1	0.023425
ZFAS1	0.023408
ERCC1	-0.023377
ADIPOR1	0.023361
AIDA	0.023320
AXL	-0.023272
CCDC58	0.023266
PMPCB	0.023240
PRPF8	-0.023224
RPS11	-0.023026
POLR2H	0.022999
ARMC1	0.022971
PHYH	0.022942
MFAP1	0.022818
RPS17	-0.022752
C1QBP	0.022680
ATP5G1	-0.022655
TCEAL4	0.022618
CBFB	0.022581
TMEM38B	0.022547
CKS2	0.022516
C2CD2	-0.022444
ARL6IP1	0.022411
GPX8	-0.022315
CCT8	0.022304
GMNN	0.022288
RPL21	-0.022220
NFKBIZ	0.022134
RRM1	0.022130
UBE2R2	-0.022114
FABP5	-0.022104
NUSAP1	-0.022016
UBP1	0.021994
MICB	0.021974
UBE2T	-0.021971
HGS	-0.021927
MYO1C	-0.021901
ID3	0.021876
DECR1	-0.021793
HSBP1	0.021786
SNRPB2	0.021775
LITAF	-0.021742
ANXA5	0.021737
COPZ1	0.021686
RPS23	-0.021536
EIF3M	0.021467
HADHB	-0.021413
EIF3D	-0.021371
CTNNAL1	0.021350
LACTB2	-0.021334
IER5	0.021317
GOLGA8H	0.021276
PLAUR	-0.021204
HLA-C	0.021162
VIMP	0.021143
ARPC1A	-0.021118
GPN3	-0.021064
PHB2	-0.021017
RUSC2	-0.020966
SNRPF	0.020899
UBL3	-0.020884
PPIB	-0.020812
ZWILCH	0.020787
UQCRB	0.020776
LGALS1	-0.020773
CERS2	-0.020757
MDH2	0.020757
UQCRC1	-0.020729
SF3B5	-0.020726
RABGGTB	0.020720
SMIM19	-0.020685
PARK7	0.020659
MED30	-0.020654
PANK3	-0.020552
CREG1	-0.020551
TRAPPC3	0.020441
VPS4A	-0.020412
UQCRFS1	-0.020392
UNG	0.020328
KIAA1191	0.020320
SNRPG	0.020315
DNAJB1	0.020303
TUFM	-0.020289
ANXA1	-0.020268
KDELR1	-0.020212
COX7B	-0.020204
ATP6V1G1	-0.020180
GNG10	0.020163
TPD52L1	0.020160
RPSA	-0.020143
STIL	0.020125
LDHA	-0.020088
MKNK2	-0.020032
RACGAP1	0.020006
POLE3	0.019994
EIF3L	-0.019961
RPLP1	-0.019893
GBAP1	0.019828
TXNDC11	-0.019820
SNHG17	0.019803
MALAT1	0.019760
STX18	-0.019760
MRPS24	0.019747
PTTG1IP	0.019745
COX14	0.019716
ATP5L	0.019714
CHUK	0.019700
FBXO30	0.019627
ATPIF1	0.019580
DCXR	0.019580
TMEM241	0.019545
ASNA1	-0.019521
ACTL6A	0.019434
VKORC1	0.019423
SLC25A6	0.019335
LSM6	-0.019306
DUT	0.019288
SMURF2	0.019243
SSR3	-0.019242
ZCCHC8	-0.019234
ND2	-0.019229
SPSB1	-0.019217
RPL31	-0.019206
PDHA1	-0.019206
SF3B4	-0.019186
GSTA4	-0.019180
UHRF1	0.019153
SLC39A10	0.019052
CHCHD2	-0.018927
HEATR2	-0.018925
WBP5	0.018895
LMNB2	-0.018894
RBM23	0.018883
PABPC4	0.018862
NAF1	-0.018855
PFDN1	-0.018840
EXOSC8	-0.018826
DBNL	0.018778
NPM1	0.018776
VAMP7	-0.018736
GPR89A	0.018735
PDCD6IP	-0.018703
ALG8	0.018686
DUSP5	-0.018655
PNP	-0.018639
TMBIM4	-0.018634
BET1	0.018631
MLF2	-0.018611
PLSCR3	-0.018587
MIF	-0.018516
TSR1	0.018469
DYNC1LI1	-0.018455
PRPF19	0.018440
HES4	-0.018416
GPN1	0.018405
ISCA2	0.018396
EIF4EBP1	-0.018385
LASP1	-0.018377
NSMCE2	-0.018352
MEAF6	0.018318
C1orf43	-0.018286
CENPW	-0.018270
CISD1	-0.018243
CWC15	-0.018201
CTH	-0.018173
ACOT13	-0.018166
ACAD8	0.018126
WWP1	0.018121
NSUN2	-0.018063
SPCS1	-0.018039
FAM206A	-0.018034
MDH1	-0.018026
H3F3B	-0.018011
CALR	0.017985
SUCLA2	-0.017973
KCTD9	0.017965
DENND4B	-0.017893
DDIT4	-0.017886