!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!cell	A375 16R6 (A375 derived GSK2118436 resistance clone)
!perturbation	GSK2118436
!disease	Melanoma - 24hrs - 1uM
!end_metadata
ATF4	0.253482
FTH1P5	0.188349
PSAT1	0.135931
GARS	0.124188
HMGN2	0.122133
RPS20	0.120938
NGFRAP1	0.113646
SLC7A5	0.112899
MT1H	-0.112036
TUBB4B	-0.108527
IARS	0.105708
RPS5	0.103097
RPL26	-0.103020
MT2A	-0.102952
ACTB	-0.099266
CTGF	-0.096733
KRTAP2-3	-0.095584
CFL1	-0.094442
RPS9	-0.092865
HIST1H4C	-0.092692
RPL19	-0.090131
TMA7	0.089725
SNHG6	0.088206
UBE2S	-0.087701
ND2	-0.086412
NOP58	-0.083881
ASNS	0.082279
TPT1	0.079791
MT1X	-0.078476
EEF1B2	0.077492
DDIT4	0.076828
S100A6	-0.076024
RPS14P3	0.074625
SNRPG	-0.074145
ANXA2P2	-0.072678
NARS	0.071534
NNMT	0.070449
MTHFD2	0.069671
ANXA2	-0.069641
NDUFAB1	0.069321
RAN	-0.067775
RPL39	0.066603
CEBPB	0.065681
KRT81	0.065285
PTMA	-0.065250
RPL21	-0.064873
PDCD10	0.063586
CDIPT	-0.063359
RPS25	-0.062678
DYNLL1	-0.062518
LGALS1	-0.061863
ERH	-0.061699
PFN1	-0.060957
SRP9	0.060216
TUBB3	-0.059672
RPL34	0.059083
SNHG5	0.059023
RPS4X	0.058685
UCA1	-0.058502
PHGDH	0.058407
XPOT	0.056995
AMIGO2	0.055596
RPS13	0.055390
HMGB2	0.054393
KRT18	-0.053745
EPRS	0.053663
ATP6	-0.053520
CCT8	-0.053399
HSPE1	-0.053067
PTX3	-0.052911
AARS	0.052003
TUBB6	-0.051572
TMEM258	-0.051488
SRSF9	-0.051073
MIF	-0.050663
RPS6	0.050054
BNIP3	-0.049723
ID1	0.049370
PPP1CC	-0.049344
NOP10	-0.048848
PTDSS1	-0.048716
RPS2	-0.048667
FTL	0.047226
RPL7A	0.046964
MT1HL1	-0.046689
RPS19	0.046425
SLC25A3	0.046317
PARK7	0.046310
MAGEA4	0.045791
CALM2	0.045628
ARPC2	-0.045525
RPL37A	0.045292
HSPH1	-0.045069
MSN	-0.044775
RPL22L1	0.044753
SLC38A2	0.044630
HERPUD1	0.044479
FKBP9	0.043973
NCL	-0.043604
C20orf24	-0.043505
RPL10A	0.042702
CAV1	-0.042452
CCND1	-0.042414
HSPA8	-0.042268
MARS	0.042152
RPL30	-0.042149
TPI1	-0.042085
S100A16	-0.041757
NAA50	-0.041690
H3F3B	-0.041431
ALDOA	-0.041421
EIF2S2	0.040333
RPLP0	0.040308
C14orf166	0.040306
FOSL1	-0.040193
RPL35	-0.040189
RPS8	-0.040135
RPL8	0.039994
TFRC	-0.039948
TMEM158	-0.039948
UQCR10	-0.039897
ERRFI1	-0.039531
ATP6V0B	-0.039457
DUSP6	-0.039311
COTL1	-0.039310
SNAPC1	-0.039255
RPS18	-0.039046
PSMD2	-0.039034
CLIC1	-0.038958
RCN1	0.038891
PLK2	-0.038714
SNRPF	-0.038707
PSMB3	-0.038662
TUBA1B	0.038593
YARS	0.037984
LDHA	-0.037762
RPS23	0.037295
CYR61	-0.037113
RPL6	0.037042
RPL11	-0.036990
RPL12	0.036987
SSR2	-0.036746
UQCRH	-0.036386
RBPJ	-0.036281
LASP1	-0.036061
ATP1B3	0.036049
MTCH1	-0.036003
DUSP5	-0.035945
IRAK1	-0.035803
FTH1	0.035527
EIF1	0.035494
SNRPB	-0.035484
HSPA1A	-0.034832
LINC00973	-0.034815
TRMT112	-0.034764
UAP1	-0.034528
ANKRD1	-0.033948
ID3	0.033741
RPL13A	-0.033459
AUP1	-0.033432
PGAM1	-0.033407
SRM	-0.033207
GPX1	-0.033006
DDX5	0.032805
FBL	-0.032739
SHMT2	0.032719
ADRM1	-0.032706
EPHA2	-0.032463
WBP5	0.032394
RPS15	-0.032354
RPL3	0.032198
FAM32A	-0.032120
DHX15	-0.032041
RPL28	0.032031
BCAT1	0.032014
TMED2	-0.031667
GTF3C6	-0.031466
TOMM20	0.031263
SSR3	-0.031258
HDGF	-0.031251
PHB	-0.031241
KISS1	-0.031127
JTB	-0.031110
SERPINE2	0.031105
CCT3	-0.031058
EIF3G	-0.030992
GAPDH	0.030944
AP2S1	-0.030909
RAP1B	-0.030892
B2M	0.030859
PPIA	0.030829
RPL24	0.030698
IL7R	0.030418
CDK4	-0.030174
TOMM5	-0.030118
MRFAP1	-0.029963
RPL9	0.029943
MCM2	0.029866
DPM1	0.029858
PSMC6	-0.029670
LDHB	0.029644
NSA2	0.029605
NUPR1	0.029592
TARS	0.029484
EIF4A3	-0.029468
ADM	-0.029453
CTNNAL1	-0.029391
LAPTM4A	-0.029349
COX1	-0.029279
HSP90B1	-0.029269
PNP	-0.029094
UBC	-0.028998
FAM136A	-0.028918
ATP5B	0.028883
ECI2	-0.028859
CTSC	-0.028731
GNG10	-0.028584
NAE1	0.028527
USMG5	0.028518
RPSA	0.028511
MMADHC	-0.028488
STIP1	-0.028440
COX8A	0.028382
HIST1H2BK	-0.028327
PPT1	-0.028271
RAI14	-0.028261
NME1	-0.028091
EEF1A1	0.027864
RPL4	-0.027759
GLRX	-0.027215
PABPC1	0.027195
CCDC86	-0.026988
TIMP1	-0.026981
PTTG1	-0.026888
WARS	0.026726
FAM96A	-0.026700
ENO1	-0.026574
SNRPC	-0.026563
UBB	0.026536
RPS24	0.026296
SLC38A1	0.026231
TRMT5	0.026093
UHRF1	0.026048
CAPN2	-0.026006
SARS	0.025956
PGK1	-0.025909
CARS	0.025877
RPL23	-0.025771
COX6B1	-0.025655
MAGEA12	0.025641
TNFRSF12A	-0.025522
RPS12	0.025500
ESM1	-0.025497
NOL11	-0.025458
SLC20A1	-0.025324
EEF2	0.025200
EBNA1BP2	0.025000
UBA2	-0.024916
RNF11	-0.024883
RPL14	0.024860
ACTG1	-0.024844
MDH2	0.024724
ARF4	-0.024685
GNG5	-0.024670
ELOF1	-0.024561
GRPEL1	-0.024394
KIAA0101	0.024225
CD59	-0.024156
EIF3D	-0.024122
CDC37	-0.024038
ADAMTS6	-0.024032
RPA3	0.023872
MRPL49	-0.023829
CRNDE	0.023689
HSP90AB1	-0.023487
RPL41	-0.023437
TSPO	-0.023385
HMGA1	-0.023376
NUCKS1	0.023373
RPL36AL	-0.023165
TAGLN2	-0.023000
NDUFS6	-0.022995
YARS2	-0.022960
TOP1	-0.022955
HSP90AA1	-0.022885
HNRNPR	0.022812
ATP5I	-0.022756
ITPA	-0.022624
PHLDA2	-0.022619
SLC25A6	-0.022521
GPI	-0.022511
RUVBL1	-0.022464
RPN2	-0.022362
PEA15	-0.022355
EDF1	-0.022080
DNAJA1	-0.021992
FOXD1	-0.021899
CIRH1A	-0.021889
COX7A2	-0.021835
PKM	-0.021806
CLTA	-0.021683
ATP5G1	-0.021664
CKS2	-0.021661
FEZ2	-0.021609
NAA38	-0.021588
PSMA7	-0.021579
RPL13	-0.021520
CD274	-0.021492
CNBP	0.021434
POLR2J	-0.021411
DDX21	0.021381
SLC7A11	0.021300
GBE1	-0.021272
RPL36	-0.021198
TXNDC17	-0.021065
CLPTM1L	-0.021001
FST	0.020912
PLAUR	-0.020906
PABPC3	-0.020886
ERP29	0.020879
AKAP12	-0.020875
RAD51AP1	-0.020849
SHC1	-0.020840
S100A10	-0.020791
KHSRP	-0.020729
MAP1B	0.020720
FAM162A	-0.020711
RPL27A	0.020710
CCT2	-0.020703
PTBP1	-0.020638
CDC26	-0.020636
MAGEC2	0.020628
VIM	0.020612
FAM129A	0.020571
ACTN1	-0.020488
PSMB5	-0.020465
MAP2K3	-0.020368
MXI1	0.020354
MELK	0.020278
ILF2	-0.020245
M6PR	-0.020240
DKK1	-0.020185
ANKRD27	-0.020089
GEM	-0.020062
RPS26	-0.020056
STOM	-0.020006
PPIB	-0.019946
PDIA6	-0.019910
PPIF	-0.019793
VOPP1	-0.019777
CDC123	-0.019743
PSMD3	-0.019702
TMEM147	-0.019678
IER5	-0.019657
FXYD5	-0.019581
NDUFB8	-0.019567
TXNRD1	0.019557
LARP1	0.019521
RPS27	0.019338
RNPS1	-0.019219
MRPL3	0.019208
RBM3	0.019207
BASP1	0.019137
PFN2	0.019108
MARCKSL1	-0.018974
WWTR1	-0.018967
CTDNEP1	-0.018965
NDUFB11	-0.018939
SLC25A32	-0.018885
CAP1	-0.018702
CNN3	-0.018671
UBE2M	-0.018624
FTSJ3	-0.018614
BZW1	-0.018588
CAPNS1	-0.018520
SNHG16	-0.018517
SRGN	-0.018484
CCT4	-0.018482
VBP1	-0.018375
MFSD1	-0.018356
HMGN1	0.018294
KARS	0.018282
DUT	0.018270
MLF2	-0.018241
CEBPG	0.018226
PALLD	0.018183
LIMA1	0.018174
RSL24D1	0.018173
TUBA1C	0.018156
DDX1	-0.018144
GPRC5A	-0.018121
SH3BGRL3	-0.018060
MAGEA3	0.018058
CEBPZ	-0.018056
MRPS35	-0.018030
SEC61B	-0.017965
RPS3A	0.017955
HSPA9	0.017927
EEF1D	-0.017898
SERBP1	-0.017892
PSMD8	-0.017878
ELOVL1	-0.017847
IER2	-0.017808
TMEM138	-0.017806
MRPS24	-0.017695
PTGES3	0.017686
EIF4EBP1	0.017631
RPL22	0.017586
RPS28	-0.017545
RBM28	0.017540
UQCRC1	-0.017535
SLC35G2	0.017530
ZMPSTE24	-0.017466
COMMD8	0.017460
HDAC1	-0.017444
SLC3A2	0.017432
PA2G4	-0.017418
ROMO1	-0.017411
RPL35A	-0.017409
DNAJB1	-0.017394
PSMA6	0.017354
XPO1	0.017333
SNRPD2	-0.017320
HEXB	-0.017280
CSRP1	-0.017266
LSM10	-0.017264
KRT80	0.017242
TMSB10	0.017158
VEGFC	-0.017131
BOLA3	0.017118
RPL36A	-0.017083
MLH1	0.017036
TXNDC12	-0.017034
EXOSC4	-0.017031
ZNF367	-0.017019
ATP5H	0.017015
KPNA2	0.016976
STAU1	-0.016972
ATP5E	-0.016905
ATP6V1F	-0.016877
CHAC2	-0.016857
UQCRQ	0.016830
LAPTM4B	-0.016815
MORF4L1	0.016738
UBE2E3	-0.016718
HUWE1	0.016710
PRELID1	-0.016661
NEDD8	-0.016620
MT1G	-0.016602
GTSF1	0.016494
SLC25A19	-0.016477
MRPL54	-0.016430
VDAC2	-0.016389
PABPC4	-0.016340
PCLO	-0.016325
NAA10	-0.016314
RPL23A	-0.016308
GBAS	0.016260
NDUFA3	-0.016252
GDI2	-0.016249
CCT5	-0.016236
WDR12	0.016177
TMX2	-0.016176
RPLP2	-0.016175
RPF2	-0.016171
TFPI2	-0.016123
GNPDA1	-0.016098
NEAT1	0.016085
PRMT5	-0.016065
LSM7	0.016014
PITPNB	-0.015979
MIR21	0.015953
SMIM20	0.015933
SPANXC	-0.015932
SPANXB1	-0.015903
EIF3E	0.015894
PSME1	0.015894
RGS4	-0.015865
TIMM17A	-0.015827
FARSA	-0.015791
NDUFA11	-0.015781
DDX3X	-0.015728
STOML2	-0.015695
MRPL27	-0.015686
RPL29	-0.015617
LGALS3BP	0.015595
DYNC1LI1	-0.015588
GNL3	-0.015539
CLIC4	0.015536
VKORC1	-0.015526
TOMM22	-0.015522
INHBE	0.015497
PLP2	-0.015435
SERP1	-0.015433
TMEM261	-0.015421
UBL5	-0.015275
TRIAP1	-0.015255
PSMA1	0.015250
HSD17B10	-0.015212
OLA1	-0.015210