!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	NICKEL
!smiles	[Ni]
!pubchem_cid	935
!cell_type	Skins biopsies from nickel-allergic patients whose skins were exposed to nickel - 7 hours
!organism	human
!end_metadata
SERPINB4	-0.171023
S100A7	-0.165242
S100A9	-0.130812
SERPINB3	-0.118941
SPRR2G	-0.112911
PI3	-0.108899
S100A8	-0.106364
SPRR2B	-0.099132
LCN2	-0.094262
CCL19	-0.078238
MMP12	-0.076911
CHI3L2	-0.062283
SCGB1D2	0.061730
CCL20	-0.061682
LTF	-0.061303
SPRR4	-0.058854
PIP	0.058688
LAMP3	-0.054725
CCR7	-0.054391
PCK1	0.052994
SERPINA3	-0.052341
C15orf48	-0.051343
CD1B	-0.050338
ZC3H12A	-0.050049
PDZK1IP1	-0.049894
LYZ	-0.049686
CIART	-0.048983
ZG16B	-0.046675
CCL22	-0.046567
A2ML1	-0.043297
MSMB	-0.042762
CYR61	-0.042629
MNDA	-0.041445
DEFB4A	-0.041362
MAMDC2	0.041324
KRTAP8-1	-0.040687
PDGFRL	0.040137
TPPP3	0.039533
SPRR1A	-0.038906
COCH	-0.037838
CCL17	-0.037699
FCGR3B	-0.037343
SERTM1	0.037318
IGF1	0.037124
CYP1A1	0.037021
KRTAP19-1	-0.036987
VMP1	-0.036452
MIR181A2HG	0.036219
BIRC3	-0.035346
LOC344887	0.035298
EHF	-0.034916
ATP12A	-0.034759
COL6A6	-0.033765
ZNF750	-0.033696
SPRR3	-0.033175
SLC6A14	-0.033100
IL32	-0.032586
C1QTNF7	0.032510
IL36G	-0.032053
PGBD5	0.032021
SCGB2A1	0.031551
KRTAP3-3	0.031519
MYH3	-0.031389
NOD2	-0.031372
TNFSF13B	-0.031333
SERPINB6	0.031165
SOD2	-0.031134
WFDC12	-0.030956
KRT85	0.030856
SPRR1B	-0.030745
IL7R	-0.030740
FKBP5	-0.030728
ZBTB16	-0.030701
ABRACL	-0.030655
FMO1	-0.030441
LOC284219	0.030399
SCGB2A2	0.030301
DCD	0.030299
LCE3D	-0.030266
PYDC1	-0.030218
G0S2	0.030197
CD1E	-0.030122
LTB	-0.029742
FHL1	0.029545
PRMT6	-0.029364
KRT35	0.029324
PCOLCE2	0.029269
OMD	0.029268
OLFML2B	0.029140
KRT34	-0.029066
CXCR4	-0.028974
ST3GAL5	0.028966
CHRDL1	0.028908
IGFBP6	0.028759
PMAIP1	-0.028631
KRT16	-0.028604
ADA	0.028472
MIR21	-0.028288
SCD	0.028231
CD1A	-0.028152
SLC44A5	0.028092
GALNT15	0.028069
CARD18	-0.027997
NFKBIZ	-0.027941
PI16	0.027911
CEACAM6	0.027807
LCP1	-0.027742
BTC	0.027640
LOX	0.027585
EPHA2	-0.027400
AQPEP	0.027370
PLIN1	0.027307
KRT18	0.027240
TIMP3	0.027234
ADCY8	0.027203
TIMP4	0.026972
CRIP1	0.026955
C14orf132	0.026867
AKR1B10	-0.026861
GFPT2	0.026712
SOX7	-0.026639
KLK6	-0.026603
ZBED8	0.026534
TSPAN8	0.026534
ERP27	-0.026506
LY6G6D	0.026479
COTL1	-0.026423
RELB	-0.026370
AQP5	0.026344
STEAP1	-0.026301
CD83	-0.025957
RGS1	-0.025946
GREM1	-0.025945
VASN	0.025922
MAB21L3	0.025901
THRSP	0.025854
CD24	-0.025805
LINC01305	0.025719
S100A3	0.025619
NID2	-0.025561
KRT6A	-0.025426
CTHRC1	0.025423
MAP1LC3C	0.025097
VCAM1	-0.025052
GABRP	0.025035
APELA	-0.025007
C5orf27	0.024962
MT1M	-0.024889
PAMR1	0.024885
SAMD13	0.024862
FABP4	0.024779
HLA-DQB2	-0.024779
HOXA10	0.024716
IL2RG	-0.024706
RRM2	-0.024669
HLA-DQA1	-0.024599
EGFL6	-0.024557
FAM46B	-0.024398
PLIN4	0.024367
GALNT12	0.024358
PCSK5	0.024227
PER1	-0.024219
CASP7	-0.024212
KRT2	0.024133
ABCA12	-0.024122
CCL27	0.024070
C19orf80	0.024066
MMP9	-0.024060
CCL13	-0.024039
TRBC1	-0.024039
SERHL2	0.023979
LEP	0.023891
HOXC9	0.023888
COPG2IT1	0.023720
HTR2B	0.023675
FOS	-0.023669
WISP2	0.023623
TSNAX	-0.023571
FCGR2B	0.023546
PCP4	0.023525
LOC100130476	0.023502
SIM1	0.023469
GCH1	-0.023468
MMP7	-0.023456
LOC729218	-0.023435
HAO2	0.023359
KRT27	0.023358
ISLR	0.023332
NPIPB15	0.023267
FGFBP2	0.023249
RERGL	0.023225
LGALS2	-0.023170
SELL	-0.023147
C12orf75	-0.023101
ITGBL1	0.023045
KRT74	0.022899
CD52	-0.022766
RASD1	0.022764
C10orf99	-0.022706
KRTAP19-3	-0.022697
SUSD2	-0.022675
ARSF	-0.022653
DONSON	0.022617
CDH3	-0.022522
UAP1	0.022510
GZMK	-0.022506
TEX40	-0.022506
CHRNB1	0.022418
C2orf42	0.022384
CPXM1	0.022302
TMPRSS4	-0.022275
KCNK2	0.022253
CXCR2	-0.022168
NIP7	-0.022140
PTX3	-0.022082
EPHX3	-0.022067
SLC37A3	0.022065
SCGB3A1	0.021997
GSTT2	0.021977
MSX1	0.021923
TNFAIP3	-0.021912
LINC00685	0.021784
FAAH2	-0.021688
ANGPTL1	0.021665
NAMPT	-0.021634
NIPSNAP3A	-0.021617
COMP	0.021448
RXRG	-0.021345
PGM2	-0.021258
ETS2	-0.021220
RAI2	0.021213
IL33	-0.021148
SGPP2	-0.021144
STEAP4	-0.021129
IL17D	0.021103
KRTAP1-5	-0.021031
ITPRIP	-0.020977
C5orf46	0.020907
KRT71	0.020891
ACPP	-0.020858
IER5L	0.020821
RBP4	0.020800
ADIRF-AS1	-0.020751
PROM1	-0.020748
HTRA3	0.020730
SHISA2	-0.020622
FLNC	0.020588
C12orf5	-0.020566
THBD	-0.020532
MYBL2	-0.020508
RASGRP1	-0.020502
ANXA3	-0.020490
MUCL1	0.020476
TMEM123	-0.020468
MARCH2	0.020385
CLCA2	-0.020380
FBLN2	0.020359
CYP4F3	-0.020351
SERPINA5	0.020320
LOC100289026	0.020301
TOLLIP-AS1	0.020254
FBRS	-0.020253
ACKR3	0.020169
MCOLN3	0.020157
ALDH1A2	0.020134
PGLYRP4	-0.020105
CD8A	-0.020072
FDXACB1	-0.020065
GRHL2	-0.020052
IGFL1	-0.020013
CEBPD	-0.019992
ADORA2B	-0.019983
DACT1	0.019957
SLC39A2	-0.019932
ST6GALNAC3	0.019902
PSRC1	0.019891
NOV	0.019860
DOPEY2	-0.019853
APOBEC3B	-0.019754
TENM2	-0.019730
REL	-0.019728
KRT77	0.019700
LOC100506497	0.019679
CFAP36	0.019616
SERPINA12	0.019591
TBCK	-0.019539
TGM5	0.019537
P2RX7	0.019533
LOC157562	0.019488
MARCKS	-0.019459
INHBB	0.019454
KRT31	0.019445
PAK3	0.019416
CILP2	0.019412
LOC100506813	0.019397
SEPT1	-0.019394
RBP5	-0.019344
ACSM3	0.019242
CRLF2	-0.019213
IRX3	-0.019191
C22orf31	0.019172
MIPEP	-0.019166
ELANE	-0.019160
TYMP	-0.019109
C8orf82	-0.019074
KIF28P	0.019067
CD207	-0.019057
CTGF	-0.019022
SNORA28	-0.018995
SLC26A9	-0.018933
MT1F	-0.018911
PSMB10	-0.018902
ZNF354B	0.018900
MFHAS1	-0.018900
CD34	0.018889
GRB14	0.018865
DDIT4	-0.018852
TFF3	0.018831
SGCG	0.018749
TMEM176A	-0.018737
SIM2	0.018732
TRIM78P	0.018729
KCNJ8	0.018719
LOC101928682	-0.018710
KANK3	0.018665
C14orf23	-0.018635
F13A1	-0.018608
PAPSS2	-0.018607
IPO4	-0.018578
PYCR1	-0.018576
SLC28A3	-0.018566
LYVE1	0.018565
PLN	0.018552
NAPSB	-0.018488
PKDREJ	0.018479
CACNG7	0.018441
PAGE5	0.018419
ELOVL3	0.018410
NFKBIA	-0.018387
SLC14A1	0.018383
KLC2	-0.018380
CTSV	-0.018357
CILP	0.018356
ZC3H12C	-0.018344
MMP27	0.018339
SPINK1	0.018325
FAT2	-0.018313
TMEM238	0.018282
KRT6B	-0.018245
MARCKSL1	-0.018235
CES1	0.018229
ISOC1	-0.018227
PKDCC	0.018202
ZNF658	-0.018191
RTP4	-0.018189
CLEC4G	-0.018188
COL6A5	-0.018175
MYADM	0.018171
CMPK2	-0.018156
LINC00959	-0.018123
KCNT2	0.018122
PRSS27	0.018121
TMEM69	-0.018104
ZNF490	0.018097
MN1	0.018049
PPP1R1B	0.018033
GAP43	0.018019
CALB2	0.018003
KRT73	0.017995
AVP	0.017981
TCHH	-0.017974
ACSBG1	0.017961
GBP1	-0.017942
CCL21	0.017924
CLEC3B	0.017915
WFDC3	0.017846
H19	0.017798
EXOC8	-0.017767
KRT75	-0.017764
LOC284014	-0.017740
NRROS	0.017735
CLIC2	-0.017733
SGK1	-0.017678
MTFMT	0.017673
IL27RA	-0.017670
SP5	0.017638
TSPAN10	0.017638
C2orf40	0.017635
FAM19A5	0.017623
CKLF	-0.017611
IGFL2	-0.017602
IFI30	-0.017596
JAKMIP3	0.017590
RRN3P2	0.017572
SUSD4	-0.017551
PLA2G2A	-0.017519
NUSAP1	-0.017502
JUN	-0.017494
ZNF267	-0.017493
CLCA4	0.017459
EML1	0.017450
CCR4	0.017435
ILF3-AS1	0.017433
KBTBD11	0.017429
RENBP	-0.017426
GALR2	-0.017421
PCDHGA4	0.017419
GREB1L	0.017416
MYO1A	-0.017397
MFAP5	0.017395
KRTAP4-1	-0.017389
CHST7	0.017384
DNM3OS	-0.017376
PPAP2C	-0.017358
F10	0.017354
DNER	0.017332
LOC101928201	-0.017325
IFI44L	0.017310
AMOTL2	-0.017233
LOC149401	0.017198
EMR2	-0.017188
IL15	-0.017171
PRRG4	-0.017144
MPZL2	-0.017138
FLJ16734	-0.017106
FLJ44896	0.017105
ELN	0.017104
TMEM140	0.017103
CYP4B1	-0.017101
CKMT2	0.017074
JSRP1	0.017061
SLC22A15	0.017046
PRMT3	-0.017043
TMEM47	0.017020
UHRF1	-0.017006
FSCN1	-0.016987
THAP1	0.016986
CTSC	-0.016975
GPAM	0.016969
VRTN	0.016925
ITGA9-AS1	0.016918
MYO1G	-0.016909
IPCEF1	-0.016906
DDX6	-0.016899
CUX2	0.016887
APLNR	0.016887
AQP9	-0.016880
RHPN2	0.016879
ASIC4	0.016850
CGRRF1	0.016840
ACKR4	-0.016835
SRPX	-0.016828
ITPKC	-0.016815
SDR9C7	-0.016801
STARD9	0.016788
RCOR2	0.016783
FLJ31713	0.016753
DSC2	-0.016744
FAM185A	0.016734
CDC42-IT1	-0.016729
CXADR	-0.016725
LOC285628	-0.016711
DSG3	-0.016665
SNX10	-0.016631
EGR2	-0.016631
UST	0.016532
LMOD1	0.016524
NELL2	-0.016523
VAV3	-0.016522
PHYHIPL	0.016506
LMNB1	-0.016494
LOH12CR1	-0.016434
BLOC1S4	-0.016426
PRR23D2	0.016425
TMEM45B	-0.016389
FIBIN	-0.016387
SH3PXD2A-AS1	-0.016381
EGLN3	-0.016375
GBP3	-0.016368
STGC3	0.016363
HSPA1A	-0.016342
SULT2B1	0.016338
CYTIP	-0.016332
FZD10	0.016321
FLRT1	-0.016274
P2RY8	-0.016226
LCE1B	0.016223
PGM5-AS1	0.016219
LRRC8B	-0.016200
TMEM132C	0.016182
LOC100506827	0.016173
LRRC49	0.016172
OSMR	-0.016169
FCGBP	-0.016142
NPR3	0.016137
SNHG24	0.016131
KCNK5	0.016114
GRIPAP1	0.016113
THBS3	0.016106
GNG10	-0.016101