!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	rat
!drug_name	Alitretinoin
!smiles	C/C(=C/C=C/C(=C/C(=O)O)/C)/C=C/C1=C(C)CCCC1(C)C
!drugbank_id	DB00523
!cell_type	lung
!organism	rat
!end_metadata
RPS21	0.250415
RPS16	-0.233232
ACTG1	0.193656
VIM	-0.154796
HSPA8	-0.152478
KDR	-0.149593
LGALS1	0.144300
PABPC4	0.142911
CYTB	-0.130777
B2M	0.123091
MGST1	-0.121592
RPS3	-0.118918
SFTPC	0.118461
ND5	0.106666
RPL8	-0.105833
RPL22	-0.102936
FAU	-0.098788
LCN2	0.091721
RPS13	-0.091061
EEF2	0.088461
FABP5	-0.088405
BSG	0.088019
LTA4H	-0.085076
RPS23	-0.082200
COX7A2	-0.081922
AHNAK	-0.081196
ND1	-0.080609
ACTA2	0.080130
RPS11	0.078120
TUBA1B	0.077383
TPT1	0.077335
RPL23	-0.077150
RPL19	0.076537
PPIA	0.076202
UBC	-0.075583
RPS9	0.075480
ALDH1A1	0.073870
CDO1	-0.073625
RPLP2	-0.073584
ATP5O	-0.073380
MYL12B	-0.072012
RPL17	-0.070817
CCL5	0.069992
SFTPA1	0.069724
ALB	-0.069433
RPL18A	0.068883
SFTPD	-0.068283
MYADM	-0.067841
RPSA	0.067518
HSP90AB1	-0.067311
ANXA2	-0.067080
RPS14	-0.066733
TMBIM6	0.066133
SCNN1A	-0.066117
SDCBP	-0.066070
ARF1	0.065476
ATP6	0.064964
SCD	-0.063957
RPL26	0.063474
RPL28	0.063257
ATP1B3	-0.061494
TAGLN	0.061468
ATP1B1	-0.060838
RPS8	-0.059561
RPL12	0.059490
NDUFB9	-0.059276
COX3	0.059124
IFITM3	0.058196
RPL18	0.058117
HP	-0.058073
SPINT2	-0.057674
COX1	-0.057624
DNAJA1	-0.057559
HSD11B1	0.057263
PDPN	-0.057252
MRFAP1	-0.053685
S100G	-0.053480
HNRNPF	-0.053146
CTSH	-0.053076
PTP4A1	-0.053066
RPL15	0.052458
HSP90AA1	-0.052420
SPARCL1	0.052103
GPX1	-0.052059
CAV1	0.051148
RPS27L	-0.051072
NDUFB3	-0.049460
YWHAB	-0.045660
RPL31	-0.044648
RPL4	-0.044567
APOE	0.044144
NRP1	0.043974
SLC29A1	0.043631
TUBB	0.043276
GPX3	0.043009
LBH	0.042676
CYP2E1	-0.042559
DDX3X	-0.042549
RAB10	-0.042275
SLC25A5	-0.042023
PRDX2	0.041756
RPL37	-0.041392
RGCC	-0.041348
CYB5A	-0.041315
MPC1	-0.041054
CYP26B1	-0.040929
RPS17	-0.040523
MYL12A	-0.040015
GNAS	0.039516
CSRP1	0.039244
CRYAB	-0.039139
ALPL	-0.039086
RPL27	0.039060
GNB2	0.038829
KRT19	-0.038529
ND2	0.038456
GSTA5	-0.038410
NDUFB8	-0.038027
IGFBP6	-0.037917
LGALS3BP	0.037660
GNB2L1	-0.037245
AKR1A1	0.036979
LDHA	0.036947
SFTPB	0.036894
CNBP	-0.036856
ANXA5	-0.036850
GAPDH	0.036741
PSAP	0.035656
NDUFA8	-0.035357
ABCD3	0.035341
TRIM8	-0.035155
ALAS2	0.034915
S100A10	-0.034870
EAF1	0.034709
RPL21	0.034687
IRF1	0.034424
TACSTD2	-0.034335
CTSD	-0.034281
CALR	0.034071
TIMP1	0.033922
CAPNS1	-0.033865
ECH1	0.033699
RPL10	-0.033424
OAZ1	0.033340
TSC22D1	0.033336
LIPA	-0.033161
CD151	-0.033153
YWHAH	-0.032980
RPL7A	0.032875
LOXL1	0.032700
HSPB1	-0.032621
RAB5B	-0.032571
RPL5	0.032350
CAPN2	-0.032313
ICAM1	-0.032299
BGN	0.032152
PLEKHA1	-0.031943
NUCB1	0.031934
PF4	0.031831
PMEPA1	-0.031742
RPL36AL	-0.031675
ACTG2	0.031532
PTTG1IP	-0.031279
CST3	-0.031201
PSMB8	0.030852
DOCK9	-0.030837
COX4I1	-0.030836
TUBA1A	-0.030834
XRCC5	-0.030731
EIF4A2	0.030731
CD9	0.030687
BNIP3L	0.030558
RPS29	0.030378
CXCL14	-0.030165
RPS6	0.030120
HSPD1	-0.030080
FABP6	0.029891
RPS12	0.029399
CTSS	-0.029330
RPS27A	-0.028703
ACAA2	0.028626
NDUFA4	-0.028484
UQCR11	-0.028442
GPX2	0.028123
CALCRL	0.028018
GFRA2	0.027949
MSN	0.027903
SERINC3	-0.027837
CD81	0.027777
GNS	-0.027773
GNB1	-0.027680
NDUFB4	-0.027608
KANK2	-0.027343
HSPE1	-0.027037
ANAPC5	0.027035
PTPRM	-0.026920
TPI1	-0.026845
UBXN1	-0.026829
TXNIP	0.026575
CD48	0.026358
ACKR3	-0.026262
HIBADH	-0.026168
FLOT1	0.026033
PSMB9	0.025873
TNFRSF1A	0.025839
COX2	0.025651
CNN3	-0.025567
CFB	-0.025431
CORO1B	0.025428
DAB2	-0.025357
UBE2J2	0.025304
TC2N	-0.025114
MRPL52	-0.024997
COX7B	-0.024488
DDR1	0.024462
NCKAP1	-0.024456
F3	-0.024398
ECE1	0.024361
COX5A	-0.024347
GNG5	-0.024277
RPL11	-0.024223
GJA4	0.024169
TTR	-0.024037
CORO1A	0.024035
GM2A	0.023993
MYH9	0.023833
PLA2G1B	-0.023736
RPS10	0.023697
CYP4B1	-0.023679
KCNS3	0.023627
BAX	0.023398
NPW	0.023263
TUBA1C	-0.023249
NDUFB10	-0.023147
FASN	-0.023083
PAICS	0.022990
RPS7	-0.022947
TALDO1	-0.022896
RAP1B	-0.022794
RPLP0	0.022728
OAS1	0.022715
TXN2	0.022689
GDI1	0.022659
CCNL1	-0.022638
RPL24	0.022612
CTBP1	-0.022538
VAMP3	-0.022384
RPS25	-0.022215
ALAS1	-0.022168
TAP1	0.022109
SPTAN1	-0.022077
AURKAIP1	-0.022060
PKM	0.022017
ACTN4	0.021917
MATR3	-0.021916
SDC4	-0.021686
TCN2	-0.021657
SLC25A17	0.021612
KLF9	-0.021362
LPL	-0.021354
PSMA6	-0.021289
ATP5F1	-0.021283
GRINA	0.021215
COX6A1	-0.021197
PPT1	-0.021174
MED25	0.021170
SEC62	-0.021158
ESM1	-0.021075
ERP29	-0.021028
SRSF11	-0.020885
PITX3	0.020856
RPS4Y1	-0.020813
NXF1	-0.020719
ACOT7	0.020683
GPX4	-0.020604
NACA	-0.020575
S100A9	0.020436
CDC42EP3	-0.020247
CTSB	-0.020238
PPP2R1A	0.020187
IL33	0.020084
GPC3	-0.019954
RPS15A	-0.019841
BIN1	0.019786
COX4I2	0.019763
IL18	-0.019629
MYL9	-0.019578
PECAM1	0.019577
APRT	-0.019559
NFKBIA	-0.019530
MDH2	-0.019422
CANX	-0.019400
ACTB	0.019347
EIF2B2	0.019332
MGP	0.019278
RPL35	0.019252
YIF1A	0.019218
P4HA1	-0.019189
P4HB	0.018993
TIMP3	0.018991
SLC3A2	-0.018989
CES1	-0.018982
CRP	0.018945
ITGB1	0.018929
PRNP	-0.018921
NDRG2	-0.018845
SDHAF2	0.018836
MAPRE1	0.018827
FGG	-0.018745
COLQ	0.018685
COX8A	-0.018608
YBX1	-0.018603
COPS7A	0.018569
PTTG1	0.018565
ENO1	0.018518
ARFGAP2	0.018503
CD74	0.018470
BMP6	0.018453
FTH1	-0.018172
NDUFA5	-0.018171
PSMB4	-0.018158
GSTM1	0.018135
EIF3D	0.018064
PRKAR1A	0.018054
NME2	-0.018008
PFN1	0.017992
EPCAM	-0.017986
AP2M1	0.017959
SEPP1	-0.017951
STAT1	0.017852
POLA2	0.017842
PPP1R2	0.017828
MFGE8	0.017708
AP2S1	0.017705
HIAT1	-0.017565
HSPA5	-0.017534
IGF2R	-0.017489
TCP11L2	-0.017461
KLF4	-0.017368
PLS3	0.017303
RPL6	0.017248
SOD2	-0.017178
DOCK8	-0.017162
NGFR	0.017080
GPR182	0.017062
AMBP	-0.017024
CFL1	0.017012
MAPK3	0.017010
ECHS1	-0.016993
CRTAP	0.016987
PER2	-0.016974
CCND2	0.016941
LYVE1	-0.016928
TMED2	-0.016824
CAPN1	0.016815
GPX7	0.016757
XPNPEP1	0.016721
SYNGR2	0.016648
ITGA1	-0.016576
EHD4	0.016512
PSMA4	-0.016509
ITFG3	0.016451
GDE1	-0.016451
PPP2CB	-0.016405
STK10	0.016368
ATP6V1B2	0.016322
HMGCS1	0.016315
LYZ	-0.016302
INO80E	0.016299
PPP1CB	-0.016272
PDHA1	-0.016218
NCL	0.016050
PRKAG1	0.016015
SULT2A1	-0.016007
HSD17B4	-0.015965
SLC25A4	0.015949
VCP	0.015943
FAM32A	0.015811
VPS45	0.015737
IRF7	0.015647
DNAJB1	-0.015591
HNRNPK	-0.015537
PRDX6	-0.015515
TKT	0.015508
APH1A	0.015458
TRAPPC3	-0.015443
CBFB	-0.015419
ALDOA	0.015376
MYO1C	0.015359
RPL14	-0.015332
APP	-0.015330
PICALM	0.015313
COA5	0.015295
GNG10	-0.015272
LPHN1	0.015263
ACADM	-0.015234
WDFY3	-0.015210
ZFP36	0.015197
APOA2	-0.015144
RBCK1	0.015117
EPHX1	-0.015102
VPS52	0.015046
AHSG	-0.015037
TSPO	0.014996
SOD1	-0.014991
HIGD2A	-0.014969
NRAS	0.014961
GPD1	0.014955
FBP1	-0.014910
CD63	0.014886
HSPH1	-0.014882
LGALS3	-0.014864
ALOX5AP	-0.014818
CCT3	-0.014774
LEMD2	-0.014738
EEF1A1	0.014702
PPP2R5A	0.014700
GDI2	0.014660
CLTC	-0.014620
CEBPB	-0.014600
ITM2B	-0.014563
KNG1	-0.014558
THBD	0.014527
TNS3	0.014521
ARF6	0.014448
MSMO1	0.014444
CTSC	-0.014418
PADI4	-0.014371
TOMM6	0.014308
RAB11B	0.014287
RPS5	-0.014285
NEDD8	-0.014226
IGBP1	-0.014209
CDK4	0.014183
LAMP2	-0.014172
RABAC1	0.014144
ACE	0.014113
NPY	0.014076
EIF4EBP1	0.014054
SRI	0.014047
LAMA3	-0.014041
SCNN1G	-0.014037
CALU	0.014023
RHOB	-0.014008
RBP4	-0.013952
TMEM47	0.013844
USE1	-0.013837
CYCS	-0.013824
UNC119	0.013804
PAWR	-0.013743
PEBP1	0.013728
BTG1	-0.013719
CSTB	-0.013645
CDC42BPB	0.013630
SCARB1	0.013627
YBX3	0.013606
CSDE1	-0.013557
HMGCS2	0.013503
SDC1	-0.013502
MVP	0.013480
ZFAND6	-0.013393
TIMP2	-0.013385
MGST2	-0.013368
CYBA	0.013364
CASP1	0.013358
CHP1	0.013313
EED	-0.013248
CA3	0.013215
OAT	-0.013134
DCTN4	-0.013122
ACTC1	0.013022
YWHAG	-0.013020
SEPW1	0.013015
STK38	-0.012994
TSPAN3	-0.012948
DYNLL1	-0.012921
GINM1	-0.012839
ATP5J	-0.012805
STMN1	-0.012730
PSME1	0.012716
EFEMP1	-0.012685
TSPAN8	0.012679
NFKB1	-0.012676
RPL27A	-0.012668
MAOB	-0.012668
MYH11	0.012648
TLN1	0.012631
PCNXL3	0.012629
ID2	0.012619
PPT2	0.012615
MARC2	-0.012608
PIK3CD	0.012564
PMP22	-0.012564
DRD3	0.012552
PJA2	-0.012502
VAMP2	0.012490
ATP5H	-0.012334
PDAP1	0.012285
IFT46	0.012269
DNAJA2	-0.012247