!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	mouse
!drug_name	quercetin
!smiles	Oc1cc(O)c2c(c1)oc(c(c2=O)O)c1ccc(c(c1)O)O
!drugbank_id	DB04216
!cell_type	liver (Western diet)
!organism	mouse
!end_metadata
SAA1	-0.250714
G0S2	-0.239406
INMT	-0.170624
TAT	0.164750
CPS1	0.163098
UBC	0.139525
APOA2	-0.136841
CAT	0.127178
PLIN2	-0.125997
ME1	-0.121632
IGFBP1	0.121318
METTL7B	-0.108062
GOT1	0.103499
ITIH4	-0.098906
SDS	0.097510
DIO1	-0.091777
BHMT	0.090705
FGL1	-0.084910
C19orf80	-0.083608
LCN2	-0.082344
TDO2	0.081330
AHSG	0.080271
SCD	0.079692
ASL	0.079519
CDO1	0.078225
CES1	-0.078009
CTH	0.077298
CIDEA	-0.076990
AKR1C4	-0.075213
OAT	0.075078
PCK1	0.074498
ELOVL5	-0.073474
ARG1	0.073304
G6PC	-0.071021
PPP1R3B	-0.070608
DUSP1	-0.067817
PEX11A	-0.067365
APOA5	0.067275
LPIN1	0.065233
GNMT	0.064734
HRSP12	0.064404
ATF5	0.063248
CYP8B1	-0.063000
BHLHE40	-0.062421
SAR1B	-0.061923
VTN	0.061000
AQP8	-0.060797
NNMT	0.060365
IFITM3	-0.059870
GLS2	0.059677
AHCY	0.059614
GLUL	-0.059439
ATP5B	0.059226
ABCB11	0.058636
ISCU	-0.057951
ABCD3	-0.057502
HSPA5	0.057279
ALAS1	-0.057031
ASS1	0.056973
FMO5	0.056693
HP	-0.056593
SERPINA1	0.055779
UQCRB	-0.055689
OAZ1	0.055674
SORD	-0.055660
CHCHD2	0.055531
RARRES1	-0.055515
HSD3B7	-0.055223
USMG5	-0.054151
ACSL1	-0.053540
ITIH3	-0.053268
LAMP1	-0.053170
THRSP	-0.053128
SLC38A3	0.052842
PPA1	0.052771
RBP4	-0.052547
FASN	-0.051246
APOE	-0.051164
CYP2E1	0.050635
AGXT	0.050348
EEF1A1	0.050141
HMGCS1	-0.049950
GSTP1	0.049899
HADH	-0.048867
SLC10A1	0.047169
ATP5G3	-0.046991
FDX1	-0.046232
CALR	0.045861
SLC38A4	0.045515
LRG1	-0.044827
ANGPTL3	0.044349
SUCLG1	-0.044345
SLC22A1	-0.044265
C3	-0.043703
FGG	0.043666
ZFP36	0.043511
RPS26	-0.043484
RPS5	0.042998
EPHX2	-0.042720
ACOX2	0.042699
C1S	-0.042613
ACSL5	-0.042572
IGFBP2	0.042545
ALDH1A1	-0.042429
GSTZ1	0.042001
SERPIND1	0.041871
HSPD1	-0.041641
TTPA	-0.041605
GSTA5	0.041158
HSP90B1	0.041112
PAQR9	-0.041049
SERPINF2	0.040913
SPP1	-0.040662
ANG	0.040567
CYP4A22	-0.040331
PNPLA7	0.040307
UGT2B17	0.040176
ITIH2	0.039964
LDHA	0.039628
FAU	0.039152
C10orf10	0.038959
ACTG1	0.038884
LYZ	0.038811
IDH1	-0.038772
RPL38	0.038680
PCBP1	0.038638
UPB1	0.038517
VKORC1	-0.038324
P4HB	-0.038004
APOC2	0.037972
CD1D	-0.037747
RGN	-0.037651
ACAD11	-0.037588
GCDH	0.037338
PGRMC1	0.037256
UPP2	0.037250
ACOX1	-0.036380
PPAP2B	-0.036339
LPCAT3	-0.036102
GPX4	-0.035966
STARD10	0.035814
FBP1	-0.035620
PAH	0.035374
RPL21	0.035317
KRT8	0.035016
ACAT2	-0.034266
SSR3	-0.034247
HSD17B6	0.034204
TKT	-0.033735
ALDOB	-0.033484
CYB5A	-0.033195
PDIA3	0.032962
ALDH6A1	0.032902
B2M	-0.032833
TMEM150A	-0.032777
F5	-0.032626
HACL1	-0.032623
RPS28	0.032530
COMT	-0.032428
ETNK2	0.032424
RPS10	0.032209
ACLY	-0.031913
IFITM2	0.031651
APOF	0.031445
RCL1	0.031235
SEC14L2	-0.031042
BNIP3	-0.031001
RPS11	0.030769
TPI1	0.030606
PANK1	-0.030049
SERPING1	-0.030017
C1QC	0.029862
GSTM5	-0.029800
LAMP2	-0.029679
GPAM	-0.029651
SLC25A39	-0.028822
SREBF1	0.028773
RPL13A	0.028734
ACADM	0.028655
RPL36AL	0.028612
RPS8	0.028515
HAL	0.028427
GPT2	0.028342
ABHD14B	-0.028251
CHCHD10	-0.028109
FGB	0.028045
RPL10A	0.028012
C8G	0.027837
TP53INP1	0.027796
SQSTM1	0.027785
HAO1	0.027775
LGALS1	-0.027725
HSD17B4	-0.027646
RETSAT	-0.027268
C9	0.027212
RPL27A	0.027178
EIF4A1	0.026964
EDF1	0.026955
ABCG5	0.026778
NIPSNAP3A	-0.026756
PYGL	-0.026624
C11orf54	-0.026605
RNASE4	-0.026506
RPS27A	0.026501
LEAP2	0.026347
PSMB4	0.026247
AASS	0.026224
FABP1	0.026016
AP3S1	-0.025968
HAGH	0.025914
CIDEB	-0.025910
EI24	0.025870
PPA2	-0.025838
ATP5H	0.025836
TFPI2	0.025782
ALDH9A1	-0.025638
AADAC	-0.025634
SLC7A2	0.025577
GLDC	0.025566
ERRFI1	-0.025548
TTR	0.025464
MPEG1	-0.025359
PLG	-0.025237
RPS24	0.024703
TUBA4A	0.024700
DBT	0.024608
CLU	0.024390
COX6B1	-0.024314
RPL18A	0.024250
SLC37A4	0.024205
NDUFA1	-0.024189
ZFAND6	-0.023862
LPIN2	0.023801
CFH	-0.023752
BGN	-0.023673
CISD1	-0.023656
ID3	-0.023476
UGT3A1	-0.023308
SLC25A5	-0.023263
MARC2	-0.023242
EIF5A	0.023239
CYP7A1	0.023111
CPT1A	-0.023104
PRDX1	0.023101
SLC27A2	-0.023035
AMACR	0.022968
CANX	0.022930
DAP	-0.022917
ADK	0.022907
SLC27A5	-0.022834
PXDC1	-0.022815
CYP1A2	0.022760
GABARAP	0.022670
GLO1	0.022559
PEBP1	-0.022530
DDX3Y	0.022514
PIGP	-0.022498
RAB5C	0.022457
IFI30	0.022448
SERPINA6	-0.022444
ALDH3A2	-0.022425
TXN	-0.022389
AKR1A1	-0.022309
RPS15A	0.022233
GSTK1	0.022159
EBPL	-0.022145
PSMB7	-0.022086
SKP1	-0.022051
GNB2	-0.021870
VSIG4	0.021814
NSFL1C	0.021812
AMY2A	0.021785
RPS23	0.021707
PEX7	-0.021651
GOLGA7	0.021536
EMR1	0.021531
APOA4	-0.021527
PIPOX	0.021517
RPL3	0.021463
SLC6A13	0.021413
LGMN	0.021266
RPL19	0.021238
SERPINA12	-0.021235
NDRG2	0.021145
MID1IP1	-0.021132
DAK	-0.021123
GJB1	0.021092
INSIG1	0.021072
SARAF	-0.021066
PPIA	0.020992
TMCO1	0.020968
ETNPPL	0.020910
NADK	-0.020899
ACAA2	0.020775
SGK2	0.020753
OPLAH	-0.020715
TF	-0.020699
EHHADH	-0.020519
NOP10	0.020478
GRINA	-0.020469
MBL2	-0.020468
GLRX5	-0.020427
CMPK1	-0.020427
PAICS	0.020376
TM4SF4	0.020360
PPARA	-0.020344
GC	-0.020246
HSD17B13	0.020210
NCKAP1	-0.020203
ABCC2	-0.020184
PLIN4	-0.020114
OTC	0.020097
PNPO	-0.020081
LIPA	-0.020076
ECI2	0.020072
VMP1	0.020062
ETFB	-0.019989
APCS	-0.019981
HINT2	0.019960
FTCD	0.019955
CCBL2	0.019910
C6orf62	-0.019891
S100A10	0.019862
GDF15	0.019815
ACSS2	-0.019809
CYP4F8	0.019797
YPEL3	-0.019717
SCPEP1	-0.019598
SUCLG2	-0.019574
GCHFR	0.019563
MAGED1	0.019557
PPIB	0.019484
APOC4	0.019438
METTL7A	-0.019410
POR	-0.019404
COX6A1	-0.019380
ALDH1B1	0.019337
HLA-DRB5	0.019279
SNX2	0.019170
EIF3F	0.019134
CSRP3	-0.019120
GJB2	0.019078
COX7A2	-0.019065
FN1	-0.019059
PIGR	0.019058
MMD	-0.019019
ABCB4	-0.019005
LGALS9B	0.018834
MPC1	-0.018770
RPL7A	-0.018731
ABCC3	-0.018728
ETHE1	0.018726
NUDT12	0.018718
SLC2A2	0.018687
HAX1	-0.018685
VNN1	-0.018591
QDPR	-0.018567
SLC16A7	-0.018525
KLF15	0.018518
GCH1	-0.018493
HGD	0.018488
NDUFB6	-0.018472
CYP4V2	-0.018330
MASP2	-0.018280
AMDHD1	0.018256
DEGS1	0.018245
NME2	-0.018136
VDAC2	0.018118
C5	-0.018110
ZADH2	-0.018104
ACOT13	-0.017948
HSD17B10	0.017883
YWHAE	-0.017881
HAAO	0.017879
SNRPD2	0.017835
RPL8	0.017773
ASPDH	0.017749
HIGD2A	-0.017712
RHEB	-0.017638
RPS21	0.017614
DDT	0.017532
KNG1	0.017507
MPND	0.017457
PHLDA1	-0.017411
TMEM176B	-0.017367
AOX1	-0.017362
ACAT1	-0.017347
HNMT	-0.017312
CBR1	-0.017263
DMGDH	-0.017263
CEBPB	-0.017220
RPLP0	0.017211
ALDH2	-0.017198
ADIPOR2	-0.017179
SLC25A15	0.017161
MORF4L2	0.017159
MANF	0.016965
HSP90AA1	-0.016895
FCGRT	-0.016827
PCTP	-0.016809
HSPB1	-0.016693
ENPEP	-0.016685
F10	0.016674
DAD1	-0.016662
GPI	-0.016638
PTTG1	-0.016609
GABARAPL1	-0.016602
NDUFS8	0.016600
RPS14	0.016593
NUCB1	-0.016540
GLUD1	0.016484
ADI1	-0.016440
ACBD5	-0.016406
SAA2-SAA4	0.016349
TMBIM6	-0.016280
AKAP1	-0.016271
IGF1	-0.016265
GBE1	-0.016229
FAM195A	-0.016179
C8orf4	-0.016148
MKNK2	-0.016080
CYP17A1	0.016080
PTPLAD1	-0.016074
PECR	0.016071
REXO2	-0.016050
ADH5	-0.015977
CLEC7A	-0.015951
EPAS1	-0.015866
PDE3B	-0.015855
PICALM	-0.015845
RAB1B	0.015837
MFSD2A	-0.015817
SLC47A1	-0.015776
C14orf1	-0.015762
RPL6	0.015724
ABCG2	-0.015694
MRPL16	-0.015677
HSD17B2	0.015663
SNX3	-0.015622
ACSM1	-0.015612
NR0B2	0.015500
LRRC58	-0.015435
CIDEC	-0.015309
RPL12	0.015304
CYP2C8	0.015250
ABHD16A	-0.015249
RPS19	0.015209
HIST1H1C	-0.015151
IQGAP2	-0.015146
NDUFS3	0.015125
SUCNR1	0.015123
AGT	0.015103
CSF1R	0.015099
PMPCB	-0.015093
GTF2A2	0.015080
SLC25A20	-0.015052
PRODH2	0.015051
CS	-0.015048
RPL24	0.015015
LECT2	-0.014904
SDC1	0.014891
TIMM13	0.014844
SLCO1B3	-0.014843
CYP7B1	0.014837
SEMA4G	-0.014804
SDHA	-0.014788
FAM120A	-0.014784
AK2	-0.014762
HERPUD1	0.014760
PXMP2	0.014751
HPN	-0.014731
ACADL	-0.014675
SERPINA7	0.014617
SDHB	0.014598
RPL4	0.014589
ACADVL	-0.014580
GLYAT	-0.014569
UCK1	-0.014457
MRPS33	0.014432
CERS2	-0.014425
NSUN2	0.014394
HIPK3	-0.014385
PAPSS2	-0.014382
TMEM50A	-0.014379
PSMC5	0.014371
BBOX1	-0.014333
RPL13	0.014331
FABP5	-0.014293
GCLC	-0.014282
TLCD2	-0.014200
DECR1	-0.014185
CXCL12	-0.014144
RPS29	0.014134
NAA38	-0.014121
HNRNPUL1	0.014072
CA14	0.014028
TP53INP2	-0.014019
AES	0.013997
TMEM256	0.013971
ABCC6	-0.013954