!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Mus musculus
!ligand_name	17beta-estradiol
!ligand_id	CHEBI:16469
!cell_type	prostate gland
!organism	mouse
!end_metadata
CA12	0.066490
SPOCK3	0.064486
ZBTB8B	0.060896
PGR	0.058623
FAM213A	0.057997
RXFP2	0.056568
TRPC6	0.055836
SPRR1A	0.050996
FGF7	0.049890
CCL13	0.049535
ANGPT2	0.045024
KCNJ14	-0.044294
EGLN3	0.044200
POU5F1	0.044126
C4orf29	0.042294
LRRC55	0.042123
BNIP3	0.040585
CENPP	0.038670
NR3C2	0.038630
OR5B17	-0.038454
SLC24A1	-0.038269
SELENBP1	0.037748
DKK2	0.037690
CADPS2	0.037679
TMEM130	-0.037576
KRT16	0.037166
GREB1	0.037165
GLP1R	0.036846
TREH	0.036431
PI15	0.036376
OR5K1	0.036325
ELMO1	-0.036297
MEIOB	-0.035354
DGKK	-0.035303
ROBO3	-0.035257
SPINK5	-0.034881
FGF18	-0.034470
C21orf62	-0.034109
KIF15	0.034029
RETNLB	0.033864
CKAP2	0.033764
BMP15	0.033664
PAMR1	-0.033619
CYTIP	-0.033592
SLC34A2	-0.033498
IFNB1	0.033193
HIST1H2AD	0.032738
NFKBIA	0.032163
HPGDS	-0.031850
OR52A5	0.031816
SPAG5	0.031795
MATN1	0.031686
RGS4	0.031626
OR4D11	0.031336
NDRG2	0.031324
TAAR5	0.031317
PROP1	-0.031291
CHRNB2	0.031025
PLIN4	0.030996
FPR1	0.030991
GMNC	-0.030986
HAND2	0.030948
CIB3	0.030801
TMEM45A	0.030787
CNTFR	-0.030735
RASD2	-0.030560
DDX25	0.030523
SERPINB1	0.030037
HIST1H2AK	-0.029937
CCIN	0.029935
NPY1R	0.029869
GRPR	0.029722
OR8G1	-0.029686
BTBD3	0.029548
FAM229B	0.029515
GPR82	-0.029416
OCM	-0.029368
LRRC4C	-0.029306
GRP	0.029233
RAD51B	0.029182
IRAK1BP1	-0.029152
EXD1	-0.029095
CRYBA1	-0.029078
OR7A5	-0.028964
SPHKAP	0.028932
SRD5A2	0.028784
OR10G2	0.028752
GC	0.028680
LRRC25	0.028635
SFTPC	-0.028618
RNF133	0.028552
LY86	-0.028517
KCTD7	0.028441
EPX	-0.028434
DAND5	0.028379
PAH	0.028009
RAG2	0.027993
ALOX15B	0.027936
HIST1H2BI	0.027930
KL	0.027794
GJD4	-0.027739
GLRX3	-0.027680
DEPDC1	0.027625
KBTBD8	0.027593
SLC6A15	0.027481
GAL	0.027452
GPR111	-0.027364
MYO16	0.027208
ACSM1	-0.027185
MGARP	0.026950
STK19	-0.026933
CEACAM18	0.026919
NMS	0.026912
ADTRP	0.026888
TAGLN3	-0.026862
ARHGEF6	0.026843
CCKBR	0.026713
SEC11C	-0.026702
CYP27B1	0.026684
VCAM1	0.026551
OR1A1	-0.026469
APOE	-0.026446
CCNB1	0.026329
MOGAT1	-0.026273
CCDC81	0.026263
BSPRY	-0.026139
LGALS2	0.026127
MME	0.026122
STEAP1	0.026056
GPHB5	-0.025936
FAM162A	0.025903
FIGF	0.025863
AADACL2	0.025855
ATP8B4	0.025832
SIM1	-0.025789
LGI2	-0.025766
KLK14	0.025719
C14orf39	-0.025629
P4HA2	0.025591
ALOX12	-0.025521
CH25H	0.025352
MRGPRE	-0.025343
KIF2C	0.025233
HIST1H2BA	0.025226
C8orf59	0.025225
KHDC1L	-0.025142
ARHGEF3	0.025133
OR13C8	0.025085
C10orf82	-0.025074
MEST	-0.024880
MMP3	0.024844
TPRG1	-0.024813
EPYC	0.024756
ATP1A4	0.024749
SH2D1B	0.024717
LRG1	0.024664
METTL21C	-0.024644
ZDHHC23	-0.024606
TAS2R40	0.024564
SLC2A1	0.024544
TF	-0.024523
NPHS1	-0.024459
WFDC8	0.024418
KLHL3	-0.024359
CRYZ	0.024346
SPATA45	0.024307
ENO1	0.024244
ZSCAN29	0.024227
OR56A3	-0.024226
PNMT	0.024223
PROCR	0.024214
KIAA1024L	-0.024209
SLC2A5	0.024173
NUDT11	-0.024162
MS4A6A	-0.024102
RTP2	0.024010
EFCAB11	0.023983
KCNA4	0.023880
C1QC	-0.023867
ITGA9	-0.023830
C9orf135	0.023787
NCR1	0.023728
HIGD1A	0.023718
ERICH3	-0.023703
SLC26A7	-0.023651
INHBC	-0.023613
PIFO	-0.023598
RAD51C	-0.023598
CRYGC	0.023594
CCDC27	0.023571
SAP30L	0.023536
OR5P3	-0.023522
WDR17	-0.023449
S100A14	0.023438
ST6GAL2	0.023426
ATP5SL	0.023401
SLC5A7	0.023390
CCNB2	0.023330
MANSC1	0.023321
DACH2	0.023317
OR2K2	-0.023299
ASIP	0.023284
TMEM178B	-0.023265
PROKR2	0.023231
CDCA7	-0.023224
CCDC157	-0.023199
C1QB	-0.023193
TDO2	0.023157
C14orf37	0.023078
CEACAM19	0.023072
ZNF438	0.023060
ZSCAN22	-0.023042
DNAH7	0.022997
FREM1	0.022992
ASZ1	0.022967
FRMD3	0.022961
CD34	0.022949
CASR	-0.022934
MMP9	0.022891
ZNF780B	0.022863
VN1R4	-0.022849
GAL3ST4	0.022847
OR5L1	0.022832
HAPLN1	0.022802
ZSCAN30	-0.022794
ZMAT4	0.022742
APCS	0.022741
TFEC	-0.022692
GNAT2	0.022692
KCNJ10	0.022683
HPD	0.022677
GIPR	0.022652
CSF1R	-0.022648
PCDHB2	-0.022621
KRTAP24-1	-0.022615
AMPH	-0.022582
ZSWIM5	-0.022559
SNRNP27	0.022550
EMR1	-0.022516
OR4B1	0.022509
KLRC1	-0.022503
LPAR1	0.022502
IER3	0.022499
MPEG1	-0.022496
IMPG1	0.022446
C14orf105	0.022428
KCNJ15	0.022400
THBS2	0.022395
OR10AD1	-0.022390
PPFIA2	0.022381
CELA3B	0.022379
CHRND	0.022370
HIST2H3A	0.022348
TMEM107	-0.022340
CAPN6	-0.022301
POU4F1	0.022300
GRIA4	-0.022297
RWDD2B	0.022279
GATM	-0.022267
OR51G1	-0.022237
TAC3	-0.022221
SDPR	0.022218
DNAJC5G	0.022203
ENTHD1	-0.022189
NUP43	0.022172
EPPIN	-0.022170
ECSCR	0.022168
MYOC	-0.022146
SPRY2	0.022115
NDUFS6	0.022097
TMEM79	0.022077
SLC51B	-0.022055
OR2AP1	0.022044
OR10Q1	-0.022034
GPR50	-0.022020
GDAP1	-0.021989
PPP1R3D	0.021983
TMEM211	-0.021980
SHROOM1	0.021976
SNRPF	0.021965
PCDHB5	-0.021962
PRELID2	0.021958
OR52M1	0.021937
OR52N2	-0.021895
FGF14	-0.021892
CXorf21	0.021886
EMCN	0.021880
CENPQ	0.021879
P2RX5	-0.021850
TEX13B	0.021847
GPR12	0.021836
TMPRSS4	0.021823
GLTSCR1	-0.021817
OR8D1	0.021774
MAGIX	0.021760
CDH10	-0.021722
VSNL1	0.021705
SLC5A1	-0.021701
TNNT3	-0.021680
OR5AK2	-0.021644
CTSG	0.021639
C1S	0.021618
IQCD	-0.021479
SPINT4	0.021454
PARVG	-0.021442
ARMC4	-0.021441
LCMT2	0.021433
IL33	-0.021432
TKTL1	-0.021429
TIGD3	-0.021401
ABCB11	-0.021396
ZNF804B	-0.021395
LPPR1	-0.021384
C6orf163	0.021374
PHYH	0.021370
WDR19	0.021339
LPL	0.021334
HEYL	-0.021313
KRTAP4-9	0.021303
GALNTL5	0.021275
MUC15	0.021257
MRPL20	-0.021256
PRM3	-0.021218
LYZ	-0.021217
ATF3	-0.021207
GPR83	0.021207
OSTN	-0.021146
IMMP1L	-0.021099
OR5H6	0.021086
SGK494	-0.021069
DOK2	-0.021066
FKBP1B	0.021023
SMIM20	0.021021
MIF	0.021015
MTERF2	0.021010
OR4A16	0.020982
CXCL16	0.020963
SP5	0.020956
OR10A3	0.020953
TTK	0.020932
VSIG4	-0.020931
C12orf73	-0.020923
CHODL	-0.020914
MYL1	0.020904
VGLL1	-0.020893
STARD6	-0.020889
TSC1	-0.020865
C2orf88	-0.020851
PFKL	0.020850
ARNTL2	-0.020846
S100G	0.020828
NANOS1	-0.020812
HCK	0.020812
STARD8	0.020808
ZNF248	0.020792
GLYATL3	0.020764
ISX	0.020757
PLSCR4	0.020749
GJA1	0.020733
ZNF286A	-0.020705
HIC2	-0.020692
KLRD1	0.020687
FUT2	0.020656
HERC6	0.020643
GABRG2	-0.020616
AQP8	-0.020615
ENPP2	0.020599
OR4C45	0.020565
DKK4	0.020560
OR52B4	-0.020551
AKAP3	0.020549
MAPK10	0.020548
ACTRT3	0.020547
PGK1	0.020537
GUCY2F	-0.020530
B3GALT6	0.020511
ALDOC	0.020417
TDRD9	0.020384
PGM1	0.020383
RWDD2A	-0.020370
C10orf107	0.020352
BHLHE22	0.020345
GRK4	-0.020339
CXCR5	-0.020338
CNNM1	0.020282
NCAPG	0.020253
C11orf86	-0.020245
ASAP3	0.020216
HOXB13	-0.020214
CNTNAP5	0.020211
HS3ST3A1	-0.020209
CORIN	0.020205
EID3	-0.020193
RXRG	0.020192
IL4R	0.020149
DKK1	0.020142
BGLAP	0.020126
LCN2	0.020101
C2orf54	-0.020093
SUSD3	-0.020088
DLGAP5	0.020086
NEURL3	0.020079
RHCG	-0.020073
OXGR1	0.020059
PRMT8	-0.020058
CARNS1	0.020051
RNASE12	0.020042
DRD2	-0.020041
BPIFA2	-0.020033
HESX1	0.020032
RIPPLY2	-0.020028
CCDC43	-0.020022
TMEM239	0.020000
GBX1	0.019994
TPPP3	-0.019992
FABP5	0.019980
PKDREJ	0.019980
ZNF804A	0.019974
SMARCA5	0.019955
POLR2K	-0.019946
TAS1R1	-0.019944
KLHDC9	-0.019931
LIX1	0.019921
UBXN10	0.019899
KRTAP4-3	0.019897
TMEM52	-0.019895
KIAA1324L	0.019880
ADORA1	0.019861
CCDC108	-0.019853
EGLN1	0.019827
DPEP1	0.019826
NCCRP1	0.019821
FABP4	0.019816
ATF7IP2	0.019802
VSX2	-0.019784
OR8B4	0.019765
EDIL3	0.019746
OR5P2	-0.019741
EDNRB	-0.019726
CEP19	0.019723
CENPW	0.019697
NKD1	-0.019680
TLR7	-0.019677
TBC1D22A	-0.019654
C9orf85	0.019628
FUT11	-0.019623
MAMDC2	-0.019617
PTPN14	-0.019613
TMEM232	0.019598
ZGLP1	0.019587
TEKT3	-0.019586
PLLP	0.019580
PRC1	0.019542
LRRTM3	0.019510
CUEDC1	-0.019509
SAMD12	-0.019503
ERO1L	0.019503
NXPH3	-0.019495
CYP1A1	-0.019487
DPP4	0.019480
OPN5	0.019468
CD14	0.019461
TMEM182	0.019461
SPOCK2	-0.019453
UGT3A1	0.019446
KRT18	-0.019437
EMC9	0.019409
CXCL3	0.019388
RBP3	0.019386
CORO6	-0.019362
SLC16A3	0.019356
ZNF3	-0.019353
TPI1	0.019343
SEPT12	-0.019328
STARD4	0.019306
SCNN1B	0.019299
FAM47E	0.019287
PM20D2	-0.019279
ZBTB8OS	0.019266
SIX3	0.019263
SERTM1	-0.019254
PPM1E	0.019246
SQRDL	0.019234
CENPE	0.019234
CCR4	0.019229
FGFR4	0.019226
IL34	0.019189
GP2	0.019182
NTN5	0.019147
INSL5	-0.019147
PIWIL2	-0.019133
OR13F1	0.019131
ST6GALNAC5	0.019117
GJA4	0.019089
BIRC5	0.019074
ARHGEF26	-0.019073
LRTOMT	-0.019065
LSM5	0.019060
CYP3A7	-0.019057
TSPO	0.019045