!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	Calcitriol
!smiles	O[C@H]1C[C@H](O)C(=C)/C(=C\C=C\2/CCC[C@]3([C@H]2CC[C@@H]3[C@@H](CCCC(O)(C)C)C)C)/C1
!drugbank_id	DB00136
!cell_type	Primary smooth muscle cells
!organism	human
!end_metadata
C15orf48	0.144102
THBD	0.128912
G0S2	0.120012
SULT1C2	0.099076
ATP1B1	0.092156
CDC42EP3	0.088831
CYP24A1	0.083690
HSD11B1	0.077168
ITPR1	0.072849
CYR61	-0.069974
CRIP1	0.067924
EFTUD1	0.067436
OSR1	0.065738
HAS2	0.061489
CCDC102B	0.061431
IDH2	0.058643
KLF5	-0.055549
MFSD6	0.055137
WDSUB1	0.055128
FAM126A	0.054817
ITPRIP	-0.054151
NINJ1	0.053648
GPR37	0.053051
LRRN3	0.053018
SLC25A25	0.050614
DHRS3	-0.050456
TNFAIP6	0.048407
GADD45A	0.048358
COL15A1	0.048211
SHE	0.048084
NME7	0.047059
PRMT9	0.046734
DPT	0.046041
ENDOD1	-0.045969
ADAM12	0.045671
DKK2	0.045645
CYP26B1	0.045613
PLEKHH2	-0.045313
RCAN1	-0.044671
IL6	0.044554
FOS	-0.044500
SRD5A3	0.044297
PLA2G4A	-0.044236
NID2	0.044010
MPP6	0.043933
RGS4	-0.043777
RARRES3	-0.043397
CHST7	0.042937
IFIT1	-0.042866
ID3	0.042585
GPCPD1	0.042230
ZFP36	0.041841
KCNK3	0.041259
NUDT4	0.041170
TMEM164	0.040893
EGR1	-0.040119
PELI2	0.039755
SLMO1	0.039748
NTN4	-0.039539
INSC	-0.039508
AKR1C1	0.039187
OSR2	0.038844
TNFRSF21	0.038821
GRAMD4	0.038749
AKR1C2	0.038748
CEBPB	0.038694
IFNE	0.038316
GALNT12	-0.038316
HMCN1	0.038315
CYP1B1	0.038138
LINC01111	0.038095
LRRTM2	-0.037901
HILPDA	0.037521
SCAI	-0.037512
PIK3R3	0.037195
KCNE4	0.037020
ARL4A	-0.036951
BCAT1	0.036813
PDE3B	0.036783
G6PD	0.036647
TM7SF2	0.036434
GNB4	-0.036379
IER3	-0.036309
FRMD4A	0.036104
LOC643733	-0.035806
INSIG1	0.035723
UGCG	-0.035611
MAP3K8	-0.035436
IFIT3	-0.035394
ZHX2	0.035381
LIMA1	-0.035119
EGFEM1P	-0.035082
CD97	0.035024
NR2F1	-0.034983
IGSF10	-0.034456
WNT2B	0.034377
MAML2	0.034204
PER2	0.034197
FOXC1	-0.034048
KHDRBS3	-0.034043
CRISPLD1	-0.034011
PMAIP1	-0.033828
LINC00968	0.033697
IGFBP3	0.033673
AGPAT5	0.033588
NPR3	-0.033584
HTRA3	0.033503
NNMT	-0.033436
SLPI	0.033410
HLX	-0.033273
SGK223	-0.032926
GPSM2	0.032642
MAFB	-0.032629
SGK1	-0.032590
MIR181A2HG	-0.032427
NFKBIA	0.032365
TLR3	-0.032201
SLC27A3	-0.031994
PIR	0.031739
MALL	0.031728
LGALS3	-0.031571
TLCD2	-0.031551
BAMBI	-0.031150
SLC7A6	0.031069
ATG5	0.031050
HIC1	-0.031021
BTC	0.031004
PPP2R3A	0.030944
CD248	0.030871
NPM3	0.030808
AKR1C3	0.030799
PPIL1	0.030760
NR4A2	-0.030728
TOX2	-0.030590
NEFM	0.030476
LINC00597	-0.030466
EDNRA	0.030430
SLC9A9	-0.030400
C4orf46	0.030315
GBP3	-0.030206
COL16A1	0.030044
SDC4	-0.029968
SLC16A7	-0.029963
PDK4	-0.029923
GREM1	-0.029893
SPATS2L	0.029879
QPCT	0.029865
SCN2A	-0.029678
DPP4	0.029659
LOC100507281	-0.029642
IRF1	-0.029568
TIMP3	0.029541
PTGER4	-0.029530
AVIL	0.029311
ATP8B1	-0.029271
FAM217B	-0.029185
GABRE	-0.029061
CLMN	0.029016
TMEM165	0.028973
FIBIN	-0.028971
TMEM55A	-0.028889
CEBPD	-0.028873
AK5	-0.028636
LEPREL1	-0.028579
EPS8	0.028372
DIRAS3	-0.028236
RASD1	0.028178
AQP3	-0.028165
FAM91A1	0.028131
CNIH3	0.028110
EVA1A	-0.028093
SLC19A2	0.028018
PAPPA	0.027950
MIR31HG	0.027925
MXRA5	0.027904
THBS2	0.027897
APBB1IP	0.027890
EML1	-0.027884
TCF7L2	0.027878
GPR68	0.027853
B3GALNT1	-0.027755
MAN1A1	0.027637
SFRP4	-0.027514
NFYB	-0.027501
SLC2A12	-0.027460
PRELP	-0.027393
VEGFA	0.027262
IGFLR1	0.027189
HLF	-0.027144
NFKBIZ	-0.026974
DOK5	0.026946
ANXA11	-0.026787
SLC39A14	0.026748
FOXD1	-0.026730
RNF175	0.026595
CAP2	-0.026555
SCN7A	-0.026543
CASP1	-0.026436
CXCL12	0.026289
CHN1	-0.026253
EPDR1	-0.026236
GALNT10	-0.026153
PRICKLE1	-0.026003
KLF6	-0.025937
NEFL	0.025887
HIF1A	0.025814
SFRP2	0.025697
GCLC	0.025634
ZFHX4-AS1	0.025603
RCAN2	-0.025512
SLC1A1	0.025496
PDE4DIP	-0.025426
FAM107B	-0.025412
OLFML1	-0.025306
AGO2	0.025227
PRR16	-0.025099
HSPA2	0.025064
GDF5	0.025057
HS3ST3A1	-0.025046
SERTAD4	0.025017
SSX2IP	-0.024984
LOC100134822	-0.024974
SCOC	0.024971
RASL12	0.024927
EEA1	0.024896
GHR	0.024777
SEMA5A	-0.024711
SLC38A2	0.024674
ENPP2	0.024657
SPON2	-0.024602
DOK6	0.024599
ZFPM2	-0.024531
MAGI2-IT1	-0.024499
MAMLD1	-0.024436
TMEM178A	-0.024434
MIR155HG	-0.024353
ETV1	-0.024344
PSTPIP2	-0.024189
ITGA4	-0.024031
ELMOD1	0.024019
HAPLN1	-0.023983
LXN	-0.023960
CLDN11	0.023889
HEG1	-0.023845
TMEM158	0.023821
INMT	0.023813
TIPARP	0.023792
SLC16A9	0.023778
GBP1	-0.023749
SMIM3	0.023674
KIAA1598	0.023623
MEF2C	-0.023578
DSEL	-0.023489
PPP1R3D	-0.023429
CPED1	-0.023426
DCBLD1	0.023417
SHB	0.023371
RNF182	-0.023359
TMOD1	0.023330
PSMB9	-0.023319
SLC35E2	0.023307
MAP2K3	-0.023284
TPD52L1	-0.023263
WDR91	-0.023239
LOX	0.023218
LPAR3	-0.023198
CRY1	0.023109
ERRFI1	-0.023098
USP13	0.023097
ATF3	-0.023067
SMG1P5	-0.023049
PTGER2	0.023038
RGN	-0.022968
CECR5	0.022963
SEMA3B	0.022943
CTPS1	0.022907
RAB9B	0.022905
CSTF2T	0.022896
ST7L	0.022808
SNX30	-0.022769
GEM	0.022625
EGR3	-0.022566
FRMD6-AS1	-0.022355
PRMT6	0.022312
SLC1A5	0.022305
TUBB2A	-0.022300
TAPT1-AS1	-0.022241
HHAT	0.022223
CDC42-IT1	-0.022218
LOC100505501	-0.022138
SH3RF3	-0.022118
SYTL2	-0.022047
FAM83D	0.021976
NSDHL	0.021950
SNORA28	-0.021945
GALNT15	-0.021922
KLHL13	-0.021900
LOC285812	-0.021872
TMEM185A	-0.021835
LIF	-0.021825
PROCR	0.021791
AGPAT4	0.021778
VPS13A	0.021750
PNPLA3	0.021744
IL17RD	-0.021647
NCALD	-0.021600
C12orf5	0.021580
NPTX1	-0.021566
LRAT	-0.021530
CDC42EP2	0.021495
LOC730101	0.021474
TBL1XR1	-0.021459
PAK1	0.021443
WDR5B	0.021368
TGFBR2	0.021306
TMEM159	-0.021278
FAM69A	0.021240
ADAMTS3	0.021180
PDGFC	-0.021145
PPP5D1	0.021144
TGFB3	0.021111
LMO4	-0.021091
HSPA8	0.021073
CTGF	-0.021033
MYO1B	-0.020990
VLDLR	-0.020981
FOXF1	0.020934
TDRD10	0.020922
PLAU	-0.020914
TPX2	0.020905
MYH10	-0.020897
NBL1	0.020880
CMC4	0.020868
TRIB2	-0.020838
INPP1	0.020834
TRIM47	-0.020832
NR3C2	-0.020821
DTX3L	-0.020810
GMDS	-0.020792
TRIM38	0.020788
ADHFE1	0.020761
GAS6-AS1	-0.020757
RHOBTB1	-0.020627
CORO6	0.020614
PLCB1	-0.020607
NOVA1	0.020592
GPR137C	0.020571
LMOD1	0.020564
ITGBL1	-0.020414
TSGA10IP	-0.020398
NTHL1	0.020383
AKIRIN1	0.020370
TXNDC11	0.020350
KAZN	-0.020348
FAM102B	-0.020337
FRMD6	-0.020308
BCL2A1	0.020246
LINC01279	-0.020223
ADAMTS1	0.020211
EIF3J	0.020203
TBC1D4	-0.020195
MLLT3	-0.020180
IFIT2	-0.020138
C1orf198	-0.020118
ZNF559	-0.020117
TSHZ1	-0.020101
LRRC75A	-0.020097
WDR86	-0.020091
C9orf89	0.020076
DDX60	-0.020052
METTL7A	-0.020041
PLBD2	0.020022
PKIB	-0.019968
ZBTB20	0.019945
AGT	-0.019895
ZNF514	-0.019887
FJX1	-0.019828
DDIT4	0.019827
STGC3	-0.019800
FAM86B1	0.019794
F2RL2	-0.019752
ANKRD13A	-0.019683
SACS	0.019658
DOCK11	0.019653
EID3	-0.019651
STIM2	-0.019645
IMPA2	-0.019634
RPS6KA5	0.019586
KCNT2	-0.019536
OLFML2B	-0.019470
PYGL	0.019429
ARL5B	0.019394
PPAPDC1B	0.019394
MX1	-0.019380
LINC00341	0.019312
BCHE	-0.019302
COPG2IT1	0.019300
NIM1K	0.019297
STON1	-0.019283
CHRDL1	0.019277
SLITRK6	-0.019275
ZFAND6	0.019263
SDC1	0.019245
SH2B3	-0.019224
SMA4	-0.019217
SEPT11	-0.019198
FAM57A	0.019197
SGCD	-0.019163
NBEA	0.019162
FBLN5	-0.019138
TM4SF1	0.019090
C10orf10	-0.019086
IRS2	-0.019074
MAPK13	0.019068
RARB	-0.019061
PRKD1	-0.019044
FOXF2	-0.019023
HMGB2	0.019007
CAPNS1	0.019000
SPIRE1	0.018971
ANKRD44	-0.018941
BZW1	0.018850
OAF	0.018825
LOC100505474	0.018819
LOC283588	0.018817
MAN1C1	0.018805
MPV17L2	0.018770
SLIT2	-0.018758
SORBS2	-0.018749
FLRT2	-0.018707
PEAR1	-0.018631
ZSWIM6	-0.018627
NMT2	-0.018624
IRF7	-0.018603
STT3A	-0.018597
PDGFD	-0.018577
PRSS12	-0.018533
TMEM140	-0.018510
EML3	0.018498
ZNF395	-0.018494
ELL2	0.018460
LOC286149	0.018453
TMEM200B	-0.018450
KCNS1	0.018444
S1PR1	-0.018377
AHNAK2	-0.018370
TSLP	0.018333
PSD3	-0.018332
AOC2	0.018330
INPP5A	-0.018293
CACHD1	0.018285
PPM1L	-0.018268
MEST	0.018232
OPTN	-0.018191
FAHD2CP	-0.018181
AAED1	-0.018165
TMTC4	0.018139
FMO1	0.018118
KNSTRN	0.018103
DCAF10	0.018101
GAB1	0.018089
WISP2	-0.018085
WSB2	0.018076
NCOA3	-0.018064
RTN4RL2	0.018030
IER2	-0.018024
KCTD11	-0.018016
COL8A2	-0.017996
PRPSAP1	-0.017954
DKFZP586I1420	0.017941
MORF4L2	-0.017929
NANOS1	0.017925
ACSL3	0.017922
SLC35B1	0.017876
TWIST1	-0.017851
C1RL-AS1	-0.017847
PLEKHA4	-0.017840
RRAS	0.017837
HES4	-0.017819
HECTD3	-0.017805
KIAA0922	-0.017790
PLEKHA2	0.017778
LOC101927027	-0.017775
BTN3A2	-0.017769
SNAPC3	-0.017761
MIR30C2	-0.017748
SLC39A11	0.017725
KPNA2	0.017712
SH3PXD2B	0.017710
EMP1	-0.017678
PDP1	-0.017675
ROBO1	-0.017655
GNA14	0.017644
LOC400756	0.017638
TGM2	0.017521
GORAB	0.017513
CXorf56	-0.017507
RNF146	0.017491
ROM1	0.017480
GUSBP3	-0.017479