!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	mouse
!drug_name	Cyclosporine
!smiles	C/C=C/CC(C(C1C(=NC(CC)C(=O)N(C)CC(=O)N(C)C(CC(C)C)C(=NC(C(C)C)C(=O)N(C)C(CC(C)C)C(=NC(C(=NC(C(=O)N(C(C(=O)N(C(C(=O)N(C(C(=O)N1C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)O)C)O)O)O)O)C
!drugbank_id	DB00091
!cell_type	No Data
!organism	mouse
!end_metadata
BPIFA2	-0.322611
GPX3	-0.275525
ACTA1	-0.206815
DNASE1	-0.152885
SPRR1A	0.137599
MYL1	-0.128915
ATP5G1	-0.122320
SQSTM1	0.119368
AMY2A	-0.110609
MYL3	0.106386
IGJ	0.102741
CHIA	-0.100029
NDUFA1	-0.099857
FABP3	-0.096749
CSRP3	-0.095637
ESD	0.089501
IDH2	0.086001
HP	-0.084157
NDRG4	-0.084123
BGN	-0.082087
MYH6	0.075106
CLU	0.073388
EEF2	-0.072897
ACTG1	-0.071637
RPS13	0.070520
COL1A2	-0.070108
CXCL10	0.070021
GRN	-0.067599
PPIA	-0.066067
BAIAP2L1	-0.065859
FHL1	-0.062640
CD74	-0.062275
RPL4	0.062028
RPL3	-0.061958
RPL23	-0.061158
LDHA	-0.060982
POSTN	0.060887
ENO3	-0.060450
PKM	-0.059976
B2M	0.058107
RPS28	-0.057874
FAU	-0.057280
SH3BGRL3	-0.056550
CST5	-0.055554
LPL	0.055043
ECH1	0.054758
SLC38A2	0.054582
CHCHD2	-0.054214
PTGDS	0.053899
CCL13	0.052927
ITGB2	-0.052712
CYBA	-0.051246
IFI30	-0.050878
EEF1A2	0.050478
TPI1	-0.049776
C1QA	-0.049705
PSAP	-0.049648
DES	-0.049525
PSMD2	0.049372
LYZ	-0.049230
MYL2	0.049046
TYROBP	-0.048440
GBP2	0.047475
CST3	0.047053
S100A8	-0.046087
COX8A	-0.046077
TNNT2	0.045335
TNC	0.044484
SARAF	-0.044211
TNNC1	-0.043877
CLIC4	-0.043742
TTN	-0.043638
RPL22	0.043351
ATP1B3	-0.043187
PLA2G7	-0.043160
SERPING1	-0.043079
PSMB8	-0.043054
ARPC2	-0.042262
UQCRFS1	-0.042106
RPLP0	0.042098
DCN	0.041733
TUBA1A	-0.041657
SMDT1	-0.041507
ANKRD1	0.041476
TCAP	-0.041171
S100A10	-0.040891
RPS8	-0.040493
LAMP1	-0.040363
FOS	0.040239
RPL13	0.040182
NPC2	-0.040091
PSMB5	-0.039998
ALPK3	0.039994
NDUFA12	0.039941
MPC1	0.039710
RPLP2	0.039693
MFAP5	0.039693
IFIT3	0.039596
RRAS2	-0.039576
SGCA	-0.039339
RHOC	-0.039060
IFITM2	-0.038958
LGALS3	0.038337
COL6A2	0.037896
PLK2	0.037499
KPNA2	-0.037446
ATP5B	0.037123
PRDX5	-0.036896
GPX1	-0.036125
CTSC	-0.036117
FPR2	-0.036030
CTSB	-0.035892
CNN2	-0.035745
BSG	-0.035663
GBP3	-0.035409
PARP3	0.035380
NDUFB7	-0.035354
SYNPO2	-0.035285
GPI	-0.035205
LCN2	-0.035092
TPT1	0.035047
ATP6V0C	-0.034837
PIP	-0.034778
TMEM147	-0.034588
HK1	-0.034401
PFN1	-0.034376
EIF3K	0.034253
CTSD	0.034139
ATP5C1	0.033959
RPS17	-0.033955
PINK1	0.033944
MEOX1	0.033942
SPTAN1	-0.033907
CALU	-0.033715
NDUFB11	0.033624
ATP5F1	-0.033416
RTN4	0.033077
COL1A1	-0.033006
LIMS2	-0.032548
BRI3	0.032504
LOXL1	0.032491
RPS3	-0.032153
SNX3	-0.032099
ACTR2	-0.032036
U2AF2	-0.031547
ARL6IP5	0.031386
MPEG1	-0.031384
MS4A8	-0.031228
ISCU	0.030808
RPS5	0.030786
ATP5O	0.030671
CYC1	0.030664
HEXA	-0.030647
GBP6	0.030565
NDUFA11	-0.030454
PGAM2	-0.030375
PARM1	-0.030291
RAC2	-0.030273
CCL5	-0.029992
RPL12	0.029837
EHD4	-0.029831
PLEC	-0.029753
UCP2	-0.029682
PSMB10	-0.029595
DDB1	-0.029370
NDUFB9	0.029203
RPS2	-0.028992
MYOM1	-0.028916
VDAC2	-0.028854
CKMT2	0.028721
TUBA1B	-0.028557
HOPX	0.028469
CCL2	0.028331
TGFBI	-0.028297
P4HB	-0.028166
ACADL	-0.028127
FAM134B	0.028115
UQCRB	0.028033
SAR1B	0.028032
FCGR2A	-0.027917
PLA2G16	-0.027839
MYOZ2	0.027825
HSP90AA1	0.027679
ARPC4	-0.027653
F2R	-0.027535
EFHD2	-0.027510
ACTC1	0.027453
CALR	0.027435
S100A9	-0.027419
BICC1	0.027262
ARHGDIA	-0.027161
SERPINE1	-0.027109
ATP1B1	-0.027071
NACA	0.027042
JUND	-0.026980
UBD	-0.026954
IFIT1B	0.026670
TNNI3	0.026560
HSPH1	0.026550
PICALM	0.026524
PSMB7	0.026438
DPT	0.026274
COL6A3	0.026159
GSTP1	-0.026151
RPL10A	0.026032
RNF149	-0.026011
RPL7	-0.025846
FHOD3	0.025727
SOD2	-0.025722
ATP1A2	0.025672
GLO1	-0.025643
GIMAP4	-0.025641
MGST3	0.025596
LDHB	-0.025562
GGH	-0.025546
GYG1	-0.025445
PF4	0.025378
MB	0.025358
CNDP2	-0.025354
RPS25	-0.025332
TAPBP	-0.025331
FLNC	-0.025223
SERPINH1	0.025084
GLRX	-0.024982
SNRPD2	0.024813
VCP	-0.024777
TECR	0.024726
C1QC	-0.024705
YIPF7	0.024606
RPS11	0.024593
ANXA5	0.024408
POMP	-0.024331
HSP90AB1	0.024309
SERPINB1	-0.024140
PDLIM5	-0.024127
NFE2L1	-0.024080
COL6A1	0.023887
RPL36AL	-0.023858
OAZ1	-0.023759
RPSA	-0.023729
SSPN	0.023658
CAV1	-0.023462
GORASP2	-0.023455
NDUFV3	0.023448
GAPDH	-0.023399
EEF1G	-0.023236
HSP90B1	0.023193
AP3S1	0.023064
TMEM234	0.023015
PRNP	-0.023009
DRAP1	0.023004
UPP1	-0.022979
MYH7	-0.022937
OXCT1	-0.022926
CHCHD10	-0.022925
GNS	-0.022913
MKNK2	-0.022909
GZMA	-0.022874
PARK7	0.022861
FBN1	0.022806
LIMCH1	-0.022749
PTN	0.022700
DENND5A	0.022691
NME2	0.022558
MGAT1	-0.022510
SLC11A1	-0.022481
ENO1	-0.022456
RPL13A	0.022411
PRKAR1A	-0.022283
RPS27L	-0.022196
UCHL1	0.022190
IRX3	0.022098
RASL11B	-0.022075
TFG	-0.022049
NDUFA7	0.022014
LSM4	-0.021998
NDUFA4	0.021904
RTP4	0.021900
NDRG2	-0.021827
IMMP1L	0.021819
CD14	-0.021785
CA6	-0.021761
SIDT2	-0.021681
SMYD1	-0.021630
LAPTM4A	0.021581
ALDH1A2	0.021518
APOBEC2	-0.021515
ADSSL1	-0.021376
PLIN2	-0.021319
CAPZA2	-0.021292
ARF1	-0.021268
FAM198B	-0.021216
IL18BP	-0.021195
JTB	-0.021140
GSN	0.021078
HSPB8	-0.020894
RHOA	-0.020884
UBE2V1	-0.020855
CCT6A	0.020853
COMT	-0.020827
CACYBP	0.020718
CORO1B	-0.020688
VIM	0.020673
CLIP4	0.020584
TIMM17A	0.020501
EMC3	-0.020346
UNC93B1	-0.020338
RNF181	-0.020323
MYL12B	0.020322
COX7A2L	-0.020247
PSMB9	-0.020220
TGM2	-0.020207
POLR2M	-0.020188
CTSZ	-0.020120
GRINA	-0.020085
SDHA	0.020056
DYNLL2	-0.020038
RPL27A	-0.020027
HSPA5	0.020006
SHISA5	-0.019975
SLC16A1	0.019950
IL2RG	-0.019849
SELT	-0.019817
PIGP	0.019801
HLA-A	0.019744
BHLHE40	0.019734
PLVAP	-0.019708
AIF1	-0.019683
MYADM	-0.019673
SPARC	-0.019590
MBNL1	-0.019518
MYZAP	0.019500
WASF2	-0.019498
COX17	-0.019485
NDUFC2	0.019464
RHOB	0.019456
ALDOA	-0.019430
MS4A7	0.019416
ZMPSTE24	-0.019392
RGS5	0.019324
HSPG2	0.019321
RPL37A	0.019315
SEPP1	-0.019279
HAX1	-0.019097
METTL22	0.018981
ART3	0.018929
CTPS1	0.018909
TMEM126A	0.018893
NKG7	-0.018892
CAT	0.018861
RELA	-0.018765
MCFD2	0.018739
SNRNP27	-0.018693
GNG11	0.018666
GLUL	-0.018618
PRDX3	0.018604
CLUH	-0.018600
LGALS9B	0.018575
TACC2	-0.018556
PABPC4	-0.018544
IER3	0.018537
SHFM1	-0.018528
MID1IP1	-0.018518
ACOT9	-0.018488
THBS4	0.018437
NDUFS7	0.018429
NDUFB3	-0.018410
MAPKAPK2	-0.018400
GDF15	0.018388
LUM	0.018360
IRG1	-0.018347
FEZ2	0.018332
PEA15	0.018327
SKP1	-0.018304
DYNLRB1	0.018284
UQCRHL	0.018231
IRF1	0.018200
OGN	0.018156
PKIA	0.018131
RPS7	0.018127
CYTH3	0.018076
CSF1R	-0.017973
MYBPC3	-0.017925
TMEM144	0.017916
CTSS	-0.017895
GPX4	0.017881
EP400	0.017834
COX6A2	0.017815
TIMM23	-0.017811
TMEM173	0.017787
EGLN1	0.017774
GRPEL1	-0.017763
MRPS34	-0.017758
BDH1	-0.017707
ATP5A1	-0.017701
GOT1	0.017687
DAD1	-0.017590
ARL3	0.017575
SMPDL3A	-0.017530
LGALS1	-0.017501
LITAF	-0.017496
DMPK	-0.017482
COX19	-0.017426
EIF5A	0.017411
C3	-0.017402
ARG1	-0.017386
NSFL1C	0.017361
S100A1	-0.017319
COX7A2	0.017315
PDCD6	-0.017304
UCK2	-0.017282
C1orf131	0.017272
CCDC80	-0.017250
COX6A1	-0.017207
BAG2	-0.017183
P4HA2	-0.017178
MYL9	-0.017141
IFIT2	0.017137
ADAM9	-0.017110
CH25H	0.017088
MRPL30	0.017087
G6PD	-0.016967
IFRD1	0.016960
CFP	-0.016945
ATOX1	-0.016927
DNAJA1	0.016824
BTG2	0.016800
LRRC2	0.016780
ALPK2	0.016773
AMD1	0.016750
MANF	0.016739
PLIN4	-0.016682
HECTD1	-0.016676
DNAJB1	0.016676
DYNLL1	0.016654
RNASE4	0.016596
FLOT1	-0.016564
FRMD5	0.016561
EIF4H	-0.016547
TAP2	-0.016487
ABLIM1	-0.016481
SGTA	0.016479
PARP14	0.016469
TMEM14C	-0.016447
PFKM	-0.016405
UBAP2	-0.016377
TUBA4A	-0.016261
RSAD2	0.016260
INPP5A	-0.016206
SLAMF9	0.016163
PMP22	0.016118
SLC25A3	0.016113
C14orf2	-0.016015
ATP5J	-0.015996
TUBA8	0.015987
AMFR	-0.015935
RABGGTB	-0.015912
AP4S1	0.015823
CEPT1	-0.015779
SUCLA2	-0.015760
MRPL20	0.015708
MINOS1	-0.015642
RPS15A	0.015637
CCT2	-0.015628
FYCO1	0.015615
MPC2	0.015603
PGLS	-0.015562
TOMM20	0.015547
PPP1R14C	0.015547
M6PR	-0.015407
CORIN	0.015376
FERMT2	0.015374
ALOX5AP	-0.015357
TMA7	-0.015334
DNAJC8	-0.015296
RPN1	-0.015231
ACTB	-0.015218
JOSD2	0.015210
SFR1	0.015191
PLEKHB2	-0.015172
PEBP1	-0.015118
LCK	-0.015112
LAPTM5	-0.015105
C19orf53	-0.015103
FTH1	0.015065
CTSA	-0.015059
RHOJ	0.015058
LMOD2	-0.015052
ATP1A1	-0.015044
WDR83OS	-0.014958
UQCC2	0.014939
PFKL	-0.014911
TPRG1L	0.014888
PSMA3	0.014880
HADH	0.014847
ICAM1	0.014810
COL5A2	-0.014772
ACO2	-0.014760
LAMTOR3	-0.014755
PRRC2A	-0.014720