!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!drug_name	FGFR-specific PD173074 inhibitor
!smiles	CCN(CC)CCCCNC1=NC2=NC(=C(C=C2C=N1)C3=CC(=CC(=C3)OC)OC)NC(=O)NC(C)(C)C
!pubchem_cid	1401
!cell_type	human multiple myeloma cell line
!organism	human
!end_metadata
KAL1	0.060789
SLC2A12	0.057125
AHNAK2	0.051541
MAP3K7	-0.050844
CDH6	0.050473
PTX3	-0.048826
SLC14A1	-0.048057
TMCO1	0.047883
TMPRSS2	-0.047205
SNORD116-21	0.046208
AMTN	0.046076
STRADB	0.045409
PTHLH	0.044185
KLHL24	0.043966
GK	-0.043077
TCP11L2	0.042703
FRMD6	0.041445
CEACAM7	-0.041134
IL18	0.040607
PMEPA1	0.039941
BMF	0.039429
CYP3A5	-0.039271
RASA4	0.039142
PPFIBP2	-0.038594
CEACAM5	-0.038329
GDF15	-0.038036
ACSM6	-0.037828
ITPR1	-0.037551
CYBRD1	0.037402
CCDC80	0.037192
IKBIP	0.037127
HBEGF	-0.037073
CYP4Z2P	-0.036186
ANKRD22	-0.035978
SULT1E1	0.035965
CALD1	0.035730
PADI1	-0.035596
CEACAM6	-0.035439
HEG1	0.035340
CACNG4	0.035274
PLA2G10	0.035209
STC2	-0.034903
MPPED2	0.034885
EVA1C	0.034801
ALAS1	-0.034323
PCDHB11	0.034176
SATB1	0.033896
CPA6	0.033856
PIK3IP1	0.033785
B3GALT5	-0.033655
SLC9A4	-0.033580
SPRR1A	-0.033539
FAM198B	0.033535
GABRQ	0.033445
ANKH	0.033111
ALDH1A1	-0.032509
ODC1	-0.032330
CEP170	0.032323
GBP4	-0.032137
APP	0.031948
BCAM	0.031870
TSPAN2	-0.031825
FOXP2	0.031779
SEPP1	0.031772
CYP4Z1	-0.031633
MARVELD1	0.031623
RRAS	0.031603
C12orf36	-0.031591
MMP2	0.031570
EGR1	0.031308
UTRN	0.031295
OAS1	-0.031279
NCEH1	-0.031076
RPS6KA5	0.030909
OCR1	-0.030838
SERTAD4	0.030563
PDPN	0.030537
PRKAR2B	-0.030475
ERI1	-0.030298
PPP2R1B	-0.030204
TIMM17A	-0.030151
RAP2A	0.030124
STS	-0.030013
JAG2	0.029918
SNORD14E	-0.029797
PKIB	-0.029674
TIMM8A	-0.029631
RAVER2	0.029620
ABCA12	-0.029552
TNNT3	0.029391
NAV2	0.029324
HMGCS2	0.029281
SLC39A10	0.029235
MT2A	0.029215
TMEM45B	-0.029022
RBBP9	0.028956
CD59	0.028898
GPX8	0.028850
MT1F	0.028811
MICAL2	-0.028791
GABARAPL1	0.028677
MFGE8	0.028523
CCNA1	-0.028465
ACER2	-0.028387
DHRS3	0.028333
ANTXR1	0.028238
DUSP6	-0.028214
CD86	0.028194
ELK3	0.028117
ZNF32	0.028019
VANGL1	0.027920
SNORD116-14	0.027670
SLC9A2	-0.027660
N4BP2	0.027580
BMP3	-0.027577
FERMT2	0.027524
APOL1	-0.027493
IRS1	0.027421
REN	-0.027288
NRXN3	-0.027258
SNORD116-18	0.027232
SLC35D1	0.027172
CDH26	-0.027130
NMRK1	0.027031
BCAS3	0.026895
MDK	0.026813
SKIL	0.026704
TBL1X	-0.026699
AOC2	-0.026615
RAB3B	-0.026577
NFKBIZ	-0.026567
CYP1B1	-0.026558
SLC1A4	0.026533
MFAP3	0.026516
ZNF615	0.026488
SCARNA9	0.026410
GOLGA7B	-0.026299
KCTD5	-0.026289
PRKCB	-0.026281
ANKRD36B	0.026266
ABCB1	-0.026231
ZNF585B	0.026217
CPA4	0.026216
ABCG2	-0.026209
MIR181A2	0.026157
STARD4	-0.026100
CA2	-0.026072
CYR61	0.026040
ADAMTS15	0.026030
HK2	-0.026027
CTGF	0.026024
CLCA2	0.025939
FAM171B	0.025872
MGAT4A	-0.025855
ZNF204P	0.025827
NID1	0.025806
CYSTM1	-0.025799
SH3TC2	-0.025797
STK32A	0.025770
ADTRP	-0.025714
TRIM31	-0.025671
LRP8	-0.025669
WIPI1	0.025641
GALE	-0.025639
FGFR2	0.025637
ZNF260	0.025590
SYT16	-0.025569
BIRC3	-0.025433
PHLDB2	0.025387
SCNN1G	-0.025345
TP53INP1	0.025313
UCP2	0.025242
CYP4F12	-0.025220
SCARA3	0.025220
MEGF9	0.025213
GTDC1	-0.025199
FHOD3	0.025183
FRAS1	0.025108
SCFD2	-0.025055
TGFB1	0.024933
TFDP2	0.024923
TMEM237	0.024902
DFNA5	0.024871
HMGCS1	-0.024831
OTUD7B	-0.024752
EMB	0.024702
CDH7	-0.024702
MIR21	0.024698
LXN	-0.024675
DLAT	-0.024642
JMY	0.024630
SCD	-0.024623
MATN2	0.024589
FRY	-0.024553
HSPB11	-0.024536
DLX5	0.024525
MMP13	0.024519
EGFR	0.024494
VTRNA1-3	-0.024486
MIR181B1	0.024484
MX1	-0.024419
TSPAN5	-0.024401
PROC	0.024395
PHLDB1	0.024355
RRS1	-0.024308
HOXD10	0.024209
LRP12	0.024178
DSE	0.024131
CLNS1A	0.024110
COX8C	0.024098
MIR181B2	0.024022
RFX5	0.023998
INSIG1	-0.023936
TNFAIP3	-0.023934
SLAMF7	-0.023911
PNPT1	-0.023864
APOO	-0.023847
PDE10A	-0.023817
SCD5	0.023772
SLC5A7	-0.023722
FOS	0.023650
SLC29A1	0.023643
CCNG1	0.023609
CD44	0.023599
ACOXL	-0.023593
HBP1	0.023577
C16orf45	0.023567
DDX26B	-0.023509
ST6GALNAC2	0.023505
TDG	-0.023475
SCEL	-0.023474
IRF1	-0.023469
SLCO1A2	0.023450
NOTCH1	0.023347
GNL3	-0.023337
GSTA1	-0.023322
FAP	0.023289
GDPD3	-0.023222
SPTSSB	-0.023216
HGSNAT	0.023155
ZDHHC2	0.023106
KCND2	-0.023099
OAS3	-0.023094
NUAK1	0.023054
CFL2	0.023035
FYB	0.023034
MICALCL	-0.022986
SDC2	-0.022935
TGFBR1	0.022933
RIMKLB	0.022927
RNF135	0.022892
PAG1	-0.022860
BHLHE41	-0.022860
ZNF33B	0.022851
LSS	-0.022843
SLC9A7	-0.022840
LIPK	-0.022819
PWAR6	0.022813
NRARP	0.022806
YPEL2	0.022797
S100A12	-0.022784
TUBA1A	0.022719
MRPL36	0.022618
GCLC	-0.022608
CAV1	0.022580
FLJ45825	0.022535
SREBF1	-0.022515
PRR15	-0.022471
CYP4F3	-0.022468
CXCL8	-0.022456
PFKFB2	-0.022451
IL1RN	-0.022417
AIM2	-0.022413
APOL4	-0.022397
DDX21	-0.022396
GSTA2	-0.022390
GTF2B	-0.022339
TJP2	-0.022302
C5	0.022300
MYADM	0.022274
MAF	0.022265
BCAT2	-0.022262
LFNG	0.022258
DYNLT3	0.022212
CHRM3	0.022201
C20orf194	0.022196
XDH	-0.022174
ITGA6	0.022156
PDE7B	-0.022135
ABCD3	-0.022108
GPR160	-0.022106
NANS	-0.022105
WDR3	-0.022099
SLAIN2	0.022043
FERMT1	0.021956
ZNF354A	0.021951
FOXN3	0.021919
STAMBPL1	-0.021895
TGFB1I1	0.021893
RUVBL1	-0.021891
DOCK8	-0.021859
EHD4	-0.021832
ZBED8	0.021829
SNORA21	-0.021828
SNORD116-20	0.021799
BCL11A	0.021764
PCDHB12	0.021762
PRSS22	-0.021757
FREM1	-0.021753
TMEM45A	0.021735
NOP2	-0.021712
MPDZ	0.021704
NPAT	0.021609
VAV2	0.021580
ACAA1	-0.021576
USP31	0.021509
GCN1L1	-0.021508
FAM162A	-0.021507
ATG10	0.021470
GOT1	-0.021459
UTP15	-0.021376
HOXA2	0.021347
LGALS3	-0.021328
PCYOX1	0.021317
AMOTL1	0.021294
HTR7	0.021291
UTP20	-0.021275
LOC283588	0.021273
LINC00324	0.021262
ZNF704	0.021252
BAMBI	-0.021223
SRPX2	-0.021222
SYTL5	-0.021209
GSDMB	-0.021201
ATP2B1	-0.021185
CCND2	0.021182
MBOAT2	-0.021182
UNC79	0.021175
RAET1E	0.021165
IFIT3	-0.021136
DLL1	0.021133
SNORD116-22	0.021119
EDN2	0.021092
ATP10D	0.021074
SEMA7A	-0.021069
PCDHB14	0.021039
LCN2	-0.021032
EBNA1BP2	-0.020988
ZNF429	0.020975
VGLL3	0.020970
GALNT4	-0.020947
SLC26A2	0.020938
PEX19	-0.020880
GRPEL1	-0.020858
KIAA0020	-0.020855
TMEM194A	0.020851
ACSL5	-0.020839
PRR15L	-0.020820
LOC100287869	-0.020813
ZNF717	0.020810
MYLIP	-0.020808
VTRNA1-1	-0.020800
AMPH	0.020715
INHBA	-0.020700
PNPLA2	-0.020685
C2orf15	-0.020683
LINC00885	0.020672
CSRP1	0.020653
UQCRQ	-0.020596
KAT2B	-0.020595
TBC1D30	-0.020591
GNE	-0.020580
AKTIP	-0.020570
SNORD30	-0.020534
TMPRSS11E	0.020508
GALNT12	-0.020492
AJUBA	0.020483
TSPYL2	0.020480
PPP2R3C	-0.020473
CITED2	-0.020455
EYA1	0.020454
PAK1IP1	-0.020427
MRPL46	-0.020383
IGF1R	0.020343
NUCB2	0.020335
SLC36A4	0.020311
CYP2B7P	0.020291
GRHL1	-0.020280
NDUFAB1	-0.020252
SLC30A4	0.020244
COX10	-0.020218
ZPR1	-0.020213
ACAA2	0.020209
YARS	-0.020193
VGLL1	-0.020164
KCNK5	-0.020159
FASN	-0.020155
ARRB1	-0.020153
CDK14	0.020153
FLNA	0.020123
CYP4F11	-0.020118
RALGAPA2	-0.020098
GABARAP	0.020085
RASEF	-0.020039
GXYLT2	0.020005
APLP2	0.019994
HCCS	-0.019991
MPHOSPH9	0.019988
MLEC	0.019980
FNDC3A	0.019919
RHOQ	0.019870
SEPN1	0.019860
DPP3	-0.019854
TARS	-0.019849
MRTO4	-0.019826
PPP1R12B	-0.019798
PS1TP4	0.019795
FAM8A1	0.019794
E2F5	-0.019781
GCA	-0.019773
DSC2	0.019747
NEO1	0.019743
SNORD116-6	0.019723
TYRO3	0.019717
METTL7A	0.019713
NDUFS3	-0.019655
PTPRK	0.019651
NALCN	-0.019633
PCDHB5	0.019602
GBP3	-0.019600
LRP1	0.019574
SDC4	-0.019490
PDSS1	-0.019482
MALL	0.019478
CSGALNACT2	0.019470
ATP1B3	0.019455
SERPINB3	0.019447
TMEM136	0.019441
VARS	-0.019434
CYC1	-0.019429
ALG1L	0.019396
SCARNA17	0.019370
KIF13A	0.019369
LBH	0.019368
EPHA2	-0.019342
CCDC92	0.019329
FZD4	-0.019311
CCL20	-0.019285
FDPS	-0.019279
C1orf21	0.019268
ATP9A	0.019265
FBXL2	0.019238
PCDHB13	0.019234
SFXN4	-0.019225
NFE2L3	-0.019180
TENM3	0.019138
COG2	-0.019133
SULF2	0.019127
EOGT	0.019121
TENM2	0.019120
OXNAD1	-0.019094
PTPRB	-0.019086
HEPACAM2	-0.019086
KLHL5	0.019083
LYN	-0.019078
OVOL1	-0.019066
NDST1	0.019055
TRIB2	-0.019043
SGK1	-0.019033
SOAT1	0.019028
TNS4	0.018986
FAM63A	-0.018982
POP1	-0.018979
TNNC1	-0.018971
SNORD116-12	0.018966
EMX2	0.018945
LGMN	-0.018935
NLGN1	0.018930
GPRIN3	-0.018916
GTPBP4	-0.018915
FASTKD2	-0.018895
BNIP3L	0.018881
LPCAT4	-0.018861
PPAT	-0.018851
POLR1B	-0.018847
TNFSF10	0.018808
MT1X	0.018791
TFRC	-0.018789
CCDC58	-0.018763
GPR87	0.018743
RASSF5	-0.018713
GATS	0.018711
PARP8	0.018700
CYCS	-0.018663
PPM1L	-0.018651
ZDHHC17	0.018648
ZNF711	0.018614
SYTL2	-0.018607
LACC1	-0.018589
WASF1	0.018582