!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	Cisplatin
!smiles	N.N.Cl[Pt+2]Cl
!drugbank_id	DB00515
!pubchem_cid	441203
!cell_type	MCF-7 cell line
!organism	human
!end_metadata
MT1F	-0.138408
MT1X	-0.128848
GATA3	-0.116406
MT1H	-0.113250
GADD45A	0.112690
IER5	0.112061
MT2A	-0.106150
MT1HL1	-0.103187
HSPA1A	0.099229
USP32P2	-0.091475
HIST1H4C	-0.091339
COX1	0.090553
TRIAP1	0.084270
IRS1	-0.077820
LMNB1	-0.075895
SFN	0.070890
KPNA2	-0.070218
BCAS3	-0.067886
PMAIP1	0.066925
MIR663AHG	0.065674
AMIGO2	-0.062303
NPTN	-0.061858
FAM102B	-0.061811
SERTAD1	0.060944
PTGES3	-0.060813
AURKA	-0.059803
SULF2	-0.058797
TUBA1A	0.058556
EMC2	-0.057602
C12orf57	0.057497
SRSF2	0.057145
BASP1	-0.056285
PRR11	-0.056271
IER2	0.055924
MAPK6	-0.055306
MIR22HG	0.055105
HSPA5	-0.054730
DYNLL1	0.054470
GOLPH3	-0.053982
DKK1	-0.053739
LXN	-0.053641
CXXC5	-0.053509
WWP1	-0.053117
SERINC5	-0.052829
UGDH	-0.052534
MAL2	-0.052055
USP32	-0.051911
SEMA3C	-0.051898
GRB2	-0.050410
RAP1B	-0.050000
SLC25A5	-0.049585
SLC38A2	-0.048879
CDKN1A	0.048784
LPCAT1	-0.048657
SAT1	0.048354
EMP2	-0.048251
BRIP1	-0.047831
SLC6A14	-0.047799
PDCD10	-0.047681
APPBP2	-0.047631
GRHL2	-0.047438
BZW2	-0.047189
UBE2C	-0.047054
CYP1B1	-0.047038
NEK7	-0.046989
MRPL32	0.046988
TPD52L1	-0.046481
RSRP1	0.046177
TRIM37	-0.045921
CTBP2	-0.045300
CLIC1	-0.044959
DPM1	-0.044919
NMD3	-0.044909
RPS6KB1	-0.044852
LRP11	-0.044704
RACGAP1	-0.044696
PPP1CC	-0.044410
MARCKSL1	0.044358
TXNRD1	-0.043792
PRR15L	-0.043577
UBA2	-0.043438
SYTL2	-0.043087
ARRDC4	0.042822
LDHA	-0.042485
RXRA	-0.042225
DEK	-0.041492
KYNU	-0.041384
CYP1A1	-0.041225
MORF4L1	-0.041192
ANP32B	-0.041145
IRF2BPL	-0.041090
TOB1	0.040912
RNF13	-0.040785
NRIP1	-0.040718
YWHAQ	-0.040659
MT1G	-0.040594
CDH1	-0.040535
INSIG1	-0.040212
TUBB2A	0.040201
SF3B4	0.040114
TERF2IP	0.039981
VIMP	0.039892
ZNF217	-0.039626
PLK2	-0.039523
CTDSP2	-0.039411
TSG101	-0.039292
CD24	-0.039291
SMIM14	-0.039222
PTMA	-0.039147
NCOA3	-0.039047
C6orf211	-0.038969
TUBB	-0.038811
ADRM1	0.038809
ISOC1	-0.038689
MREG	-0.038388
PPP3CA	-0.038074
HK1	-0.038068
METRNL	-0.037933
CACNG5	0.037730
CMC2	-0.037273
TPX2	-0.037191
ARL8B	-0.036825
NDUFAB1	-0.036711
ZFP36L2	-0.036200
KRT18	-0.036156
GDF15	0.036088
YWHAZ	-0.036081
PUM1	-0.035895
RAB10	-0.035838
PRC1	-0.035823
FUT8	-0.035756
CA2	-0.035654
HIF1A	-0.035621
CAV1	-0.035453
FAM83D	-0.035316
RAB1A	-0.035238
GPBP1	-0.035229
DCXR	0.034961
AARS	-0.034938
DYNLT1	0.034884
HSPA2	0.034846
CTCF	-0.034812
KLHDC2	-0.034727
ERH	-0.034655
ND2	0.034540
SLC7A2	-0.034449
EIF4A1	-0.034318
SRRT	0.034159
MELK	-0.034058
ZFAND2A	0.034052
GNAI3	-0.034047
PFN1	0.034009
ANLN	-0.033943
CSDE1	-0.033842
ID2	0.033791
STAU1	-0.033622
LINC01003	0.033610
SDCBP	0.033453
YEATS4	-0.033369
PSMB1	-0.033349
MESDC1	0.033341
TUBA1C	-0.033106
CENPA	-0.033091
MTCH1	0.033079
NET1	-0.033007
HILPDA	-0.032954
NIF3L1	-0.032945
TRIQK	-0.032935
DLGAP5	-0.032876
ANXA2P2	-0.032876
ASAP2	-0.032851
EIF3E	-0.032787
PSMC6	-0.032708
NSMCE2	-0.032681
MIR21	-0.032680
KRT8	-0.032570
HAT1	-0.032491
TOP2B	-0.032456
UBE2S	-0.032398
PTPRK	-0.032341
SRP19	-0.032239
SLC7A5	-0.032208
CCNB1	-0.032201
NR2F2	-0.031964
TRIM16	-0.031845
RAN	-0.031713
MRFAP1	-0.031672
JARID2	-0.031632
FAM53C	0.031577
KANSL1	-0.031541
PSMG2	-0.031443
PRDX1	-0.031423
ANKRD27	-0.031396
RBMS1	-0.031207
TUBD1	-0.031144
DHRS2	-0.031094
CHCHD3	-0.031029
NUP35	-0.030956
NUSAP1	-0.030857
SLC38A1	-0.030820
RPA3OS	-0.030679
SPIN1	-0.030554
SRSF6	0.030547
TBCA	-0.030512
MRPL49	0.030503
NXF1	0.030438
PCBP1	-0.030257
ERMP1	-0.030199
ESRP1	-0.030168
DNAJB11	-0.030165
CDKN3	-0.030026
PLEKHF2	-0.029957
TTK	-0.029910
TMEM14B	-0.029865
SEC24B	-0.029814
MRPS28	-0.029539
TRIM33	-0.029408
SLC25A6	-0.029368
MLPH	-0.029281
HMGB2	-0.029004
SLC25A3	-0.028966
BAMBI	-0.028958
CCDC115	0.028921
PIM3	-0.028895
EPC2	-0.028755
RPL7L1	0.028670
ISG15	0.028637
RPA3	-0.028630
ETFA	-0.028286
ANXA2	-0.028283
SELK	0.028248
PSMA6	-0.028184
APP	-0.028153
ELOVL7	-0.028061
UBE2E3	-0.028051
KRT19	-0.028035
NRARP	0.028019
LOC100129361	0.028018
CDKN1B	-0.028009
TMBIM4	-0.027993
SH3BP5	-0.027991
SEC13	-0.027963
H3F3B	-0.027961
NRAS	-0.027799
FTH1	-0.027755
ANKRA2	0.027750
OSBPL9	-0.027739
TXNIP	-0.027726
ATP9A	-0.027680
C1QBP	-0.027636
CHST15	-0.027623
RAD51C	-0.027614
LSR	0.027585
HEATR6	-0.027553
XPO6	-0.027546
POTEKP	-0.027439
COX2	0.027390
NDUFB11	0.027375
TPD52	-0.027278
SPINT2	-0.027253
TMEM14A	0.027220
RTN4	-0.027184
ADNP	-0.027120
AKR1C2	-0.027084
NDC80	-0.026998
ACTB	-0.026900
NUCKS1	-0.026844
FDFT1	-0.026741
FAM83B	-0.026741
RNF149	-0.026737
MRPS23	-0.026705
KLF10	0.026666
SRSF3	-0.026663
TRMT112	-0.026660
FOXO3	-0.026641
FNBP1L	-0.026507
COX8A	-0.026381
MAEA	-0.026278
RPL3	-0.026269
PNRC1	-0.026256
BUB1B	-0.026244
ATP8B1	-0.026232
GAPDH	-0.026212
SMG8	0.026135
NR3C1	-0.026071
SNRPF	-0.026023
C14orf119	0.025996
TEX2	-0.025914
HMMR	-0.025804
STAG2	-0.025772
XPOT	-0.025754
DSCAM	-0.025750
XBP1	-0.025627
RAD23B	-0.025623
IER5L	0.025619
GDI2	-0.025526
MB21D2	-0.025482
HAUS3	0.025451
SPATA20	0.025448
IER3	-0.025419
ISCU	0.025366
COX7A2	0.025365
ACTR3	-0.025336
GBE1	-0.025233
VPS37C	-0.025139
NUP37	-0.025068
PAPOLA	-0.025037
HES6	0.025007
S100A13	0.024980
KRT10	0.024914
PKD1P1	0.024909
PPP2R5E	-0.024899
CD9	-0.024886
AGR3	-0.024874
GPR160	-0.024843
PPA1	-0.024821
CBX4	0.024800
NMB	0.024744
RAB8A	-0.024740
TBC1D9	-0.024603
ARMCX6	0.024562
HIST1H2BF	-0.024532
CCNG1	0.024423
ARPC1A	-0.024397
SLC10A3	0.024362
RPL8	-0.024352
UBQLN2	0.024345
RARS	-0.024343
HSPH1	0.024325
HJURP	-0.024312
MAP4K3	-0.024270
TUBA1B	-0.024208
RPL36	0.024188
MBTPS1	-0.024181
PTTG1	-0.024114
HNRNPDL	-0.024018
ZDHHC7	-0.024005
DHX15	-0.023901
NIPSNAP3A	0.023858
CDCA3	-0.023846
MOAP1	0.023796
SLC35A1	-0.023727
UBE2G1	-0.023723
NOL11	-0.023674
CSE1L	-0.023658
SHOC2	-0.023608
SLC39A6	-0.023602
WAC	-0.023571
SGMS1	-0.023571
NPIPA1	0.023568
MTDH	-0.023563
ZNF263	0.023512
SPTSSA	-0.023497
PPDPF	0.023493
H2BFS	-0.023407
RCC2	-0.023388
PHLDA2	0.023357
PTRHD1	0.023318
G6PD	0.023278
PSMD14	-0.023262
MICU2	-0.023228
SYT1	-0.023228
BOD1	-0.023207
CALM2	-0.023198
CETN3	-0.023164
SUMO2	-0.023096
HIST1H2BK	-0.023072
CKS2	-0.023068
FAM103A1	0.023046
MOB4	-0.023023
ZNRF1	-0.022877
TOP1	-0.022867
PMEPA1	-0.022811
PTBP1	-0.022809
TRIM24	-0.022771
MAP2K1	-0.022758
DDIT4	-0.022752
SND1	-0.022614
IRF7	0.022607
PNRC2	-0.022591
VAV3	-0.022517
KIAA0247	-0.022498
NOP58	0.022484
TSPAN13	-0.022470
IGF1R	-0.022467
SNRPD1	-0.022451
DNAJA1	0.022445
ATP6V0D1	-0.022378
SNX10	-0.022374
PSMC4	0.022373
RUSC1	0.022362
SEPW1	0.022268
TM9SF2	-0.022265
GTF2IRD1	-0.022210
MAD2L1	-0.022200
MYD88	0.022180
BLOC1S2	0.022135
IDI1	-0.022110
RAB9A	-0.022083
SYAP1	-0.022044
SCAF8	-0.021988
ALYREF	-0.021981
SPOPL	-0.021898
GDI1	0.021896
AMOTL2	-0.021892
CAMLG	0.021892
FOS	0.021861
CBX1	-0.021815
BRD2	0.021809
DDX41	0.021801
SNHG15	0.021800
PARN	-0.021747
RBM18	0.021745
CNOT6	-0.021716
C1orf109	0.021663
TBCC	0.021609
RPS8	0.021528
ABL1	-0.021521
LYPD6B	-0.021467
C9orf78	0.021436
STRA13	0.021435
C1orf122	0.021430
ZC3H4	-0.021415
UBE2E1	-0.021405
H2AFZ	-0.021389
COX14	-0.021366
DHX40	-0.021339
STK24	-0.021311
LINC00052	-0.021275
SMAP1	-0.021219
SNRPA1	-0.021156
MED13	-0.021146
HIST1H2BD	-0.021091
SRSF9	-0.021071
HMCN1	-0.021029
WBP1L	-0.020993
PDIA6	-0.020920
INAFM1	0.020900
UBE2D2	-0.020900
CBX3	-0.020852
HLA-A	0.020828
C14orf2	0.020809
ZDHHC20	-0.020802
CXorf40A	-0.020760
NEAT1	-0.020758
EFR3A	-0.020744
FAM89B	0.020741
BTG2	0.020740
EEF1G	-0.020740
TMEM128	0.020710
STK39	-0.020666
PPP6R3	-0.020650
UGP2	-0.020649
EPS8	-0.020641
PPP3R1	-0.020611
ASNSD1	0.020606
ISCA2	-0.020560
SIRT7	0.020538
INTS8	-0.020525
RDX	-0.020480
UBE2R2	-0.020459
ATP6V1E1	-0.020458
EI24	0.020451
SKA2	-0.020451
SASH1	-0.020387
KCNJ3	-0.020373
ODC1	0.020369
UBE2T	-0.020368
PICALM	-0.020366
RPS3	-0.020303
PDRG1	0.020285
SRPK2	-0.020226
FGF13	-0.020213
MRPL27	-0.020161
EFNA1	-0.020156
SEC11A	-0.020147
GFRA1	-0.020130
TLE1	-0.020089
CAPNS1	0.020078
ARFIP1	-0.020073
SDF2L1	-0.020049
ATG5	-0.020006
THAP10	0.019989
ADK	-0.019970
C14orf166	-0.019954
SLC2A1	-0.019941
PKM	0.019932
HERPUD1	-0.019927
SRP14	0.019921
S100A11	0.019868
LCMT1	-0.019845
RPL11	-0.019836
LCLAT1	-0.019834
ZNF706	-0.019834
FBP1	-0.019811
PCNA	0.019805
TKT	-0.019788
RBBP7	-0.019780
LAP3	0.019750
PAN3	-0.019724