!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	rat
!drug_name	Methylprednisolone
!smiles	CC1CC2C3CCC(C3(CC(C2C4(C1=CC(=O)C=C4)C)O)C)(C(=O)CO)O
!drugbank_id	DB00959
!pubchem_cid	6741
!cell_type	Skeletal muscle - 30 minutes
!organism	rat
!end_metadata
HSPB6	-0.211489
ATP2A1	0.194512
CRYAB	-0.184152
COX2	-0.177968
RHOB	0.174504
ZFP36	0.170342
NDUFB9	-0.147992
ACTN2	0.137129
PABPC4	0.134865
MYL2	-0.133906
ASB2	0.129515
NFKBIA	0.127724
UBC	0.119997
PPP2R5A	0.119437
MYH7	0.114031
LGALS1	-0.106266
TECR	-0.105624
MGP	0.100246
TCAP	-0.098532
RRAD	0.098318
MYBPC2	0.097398
TXNIP	0.096333
ND2	-0.087440
ACTG1	-0.085726
COX3	-0.083311
NDRG2	0.081602
IFITM3	0.081357
RPS13	-0.080919
CEBPB	0.080828
ATP5B	0.080446
H19	-0.079409
TNNC2	0.079092
CKM	0.077961
RPL9	-0.076577
MGST3	-0.074852
SPRY1	0.074687
JUNB	0.070991
CASQ1	0.069735
VDAC1	-0.069589
CLU	0.068958
CA3	0.068583
FAU	-0.068183
PYGM	0.067806
TUBA1A	-0.067034
TUBA4A	-0.066880
RPLP2	-0.066624
MYL3	0.065633
FTH1	0.065227
RPL39	-0.064886
NDUFS7	0.064308
MDH2	0.064270
COX6A2	0.064179
ACTC1	-0.063794
RPL37	-0.063352
CHRNA1	-0.062738
ALDH1A1	0.062691
LDHB	-0.061578
ATP6	0.059473
CXCL2	0.059173
CYC1	-0.058969
MYL12B	-0.058313
RPL22	-0.057952
NDUFC1	-0.057314
IDH2	-0.056587
LITAF	0.055717
CYCS	-0.055354
NDUFB6	-0.054691
CSRP3	-0.054673
NDUFA4	-0.054645
FXYD1	-0.053602
POSTN	-0.053379
FTL	-0.053112
LDHA	0.053098
ATP5F1	-0.053067
NR4A1	-0.052592
GNAS	0.052498
CEBPD	0.052075
TNNT3	-0.051314
ACADL	-0.051241
VIM	-0.050903
ACTB	-0.050586
ENO3	-0.050396
AUH	0.050372
RPS3	-0.049476
RPS27L	-0.049376
PTP4A2	0.049371
PSMB5	-0.048929
RPS16	-0.048500
RPS8	-0.047966
UCP3	0.047910
MYH6	0.047721
TXN2	0.047714
LDB3	-0.047496
SLC25A4	0.047304
MYH1	-0.047005
HSPA8	-0.046941
GOT1	-0.046810
RPS23	-0.046576
MORF4L2	-0.046355
PKM	0.045506
PAICS	0.045254
RPSA	-0.044973
PPP1CB	0.044915
MRFAP1	0.044867
RPS15A	-0.044781
CKMT2	-0.044308
IRF1	0.044305
CACNG1	-0.044208
ATP5H	-0.043886
ANKRD1	-0.043241
ERRFI1	0.043173
RPS25	-0.042836
ATP5G1	-0.042806
FABP3	-0.042625
SLC2A4	-0.042091
RPL11	-0.041855
CBFB	0.041400
TSC22D1	0.040780
NDUFB3	-0.040686
ALDOA	0.040683
JUN	-0.040546
SGK1	0.040517
COX4I1	0.040035
ENO1	-0.039994
MYLPF	0.039536
KLHL41	-0.039476
DES	0.039449
TNNI1	-0.038880
TFRC	-0.038749
PVALB	0.038393
GNB2L1	-0.037883
AK1	-0.037857
RPS27A	-0.037814
RPL15	0.037593
TRIM54	-0.037310
RPL4	-0.037309
MYCBP2	0.037034
LUM	-0.036924
RPS9	-0.036636
SDHA	0.036035
ATP5C1	0.035731
TUBA1B	-0.035284
SELP	0.035235
DOCK9	0.035216
SVIL	0.035103
SPARC	-0.035060
MYL4	-0.034997
EEF1G	-0.034929
GSTP1	-0.034614
H1F0	-0.034294
NDUFA9	-0.034109
PARK7	-0.034087
CNBP	-0.033449
RPS17	-0.033393
TUBA1C	0.033361
PFKFB3	0.033238
DLST	-0.033180
HP	0.033129
PTOV1	0.033023
ARL4A	0.032831
GRINA	-0.032770
GADD45A	0.032642
HSPB1	-0.032542
PPP3CA	0.032487
RPL3L	-0.032470
MYL9	-0.032422
PPIA	-0.032393
ATF3	-0.032317
RPS10	-0.032291
PTP4A1	-0.032078
RPS5	-0.031996
DBP	-0.031947
ID3	-0.031852
MYH2	-0.031829
RPS21	-0.031779
PDE4B	0.031732
TIMM17A	-0.031629
CAP2	-0.031071
UQCRC2	0.030883
MYL12A	-0.030716
DYNLRB1	0.030534
BTG1	0.030464
SOCS3	0.030349
COL1A2	0.030134
SDCBP	0.030043
DCN	0.029762
ACTA1	0.029744
FOS	-0.029452
ATP1B1	-0.029278
RPL13A	-0.029194
GLUL	0.029068
RPL10A	0.029067
PSME1	0.028991
FABP4	-0.028940
F2R	0.028645
MFGE8	-0.027639
MAPK6	-0.027527
LAMTOR1	-0.027508
GSTM1	-0.027498
RPL3	-0.027364
UQCRFS1	0.027349
YWHAE	-0.026978
YBX3	-0.026945
MRPL3	0.026884
MYF6	-0.026854
KLF4	-0.026776
CD63	-0.026680
SLC41A3	0.026639
PSMD2	-0.026580
NME2	-0.026390
NR1D1	-0.026390
RAB10	-0.026276
CTSD	-0.026209
CYTB	-0.026033
ARF1	-0.026003
CHRNB1	-0.025849
RPL27A	-0.025848
SLC6A8	0.025459
PITPNA	0.025403
GPX1	-0.025359
RPS4Y1	-0.025315
ID1	-0.025228
CALU	-0.025156
CXCL14	0.025145
DNAJA1	0.025101
RPL7A	-0.024866
EMP1	-0.024635
AQP1	0.024358
COX7B	0.024311
CPT1B	-0.024291
ALDH2	0.024237
TCP11L2	0.024220
PSMC3	-0.024208
RPLP0	-0.024094
CST3	0.024019
SLC16A3	-0.023975
RPL18	-0.023954
RPL27	-0.023840
HSP90AA1	0.023676
COX6A1	-0.023547
RPL28	-0.023445
FSTL1	-0.023371
HSPD1	-0.023289
ACTA2	-0.023175
VPS4A	0.023156
COX7A2	-0.023146
CTSV	-0.022874
YWHAG	-0.022718
PPP2CA	-0.022662
ANXA5	-0.022643
DNAJB5	-0.022555
USP19	0.022492
ZNRF1	0.022420
ATP5G2	0.022280
TPI1	-0.022183
NFKB1	0.022160
TMA7	-0.022146
NFIX	0.021957
RPL17	0.021956
S100A8	0.021823
ADM	0.021773
SNRNP70	0.021710
EEF1A2	0.021709
COX7A2L	-0.021683
NDUFA5	-0.021625
FABP6	0.021546
PSMA7	0.021511
TUBB	-0.021507
SNRPB	-0.021466
RPL19	-0.021450
ITGB1	-0.021404
IGFBP3	0.021374
RPL36AL	-0.021276
S100A4	-0.021188
HIGD2A	0.021135
LYZ	-0.021082
CD36	-0.020872
FABP5	-0.020828
ADK	-0.020774
CD151	-0.020741
TMOD1	0.020661
GAPDH	0.020638
CYB5R1	-0.020636
TIMM23	-0.020539
ATP1B3	-0.020499
NAPA	0.020491
TCEB1	-0.020483
IVD	0.020411
CSDE1	-0.020361
PRDX3	0.020197
CITED2	0.020185
PPP1CA	-0.020024
MYL1	-0.020002
DCAKD	0.019879
MYC	0.019859
SLC25A5	-0.019819
COX5A	0.019804
CLTA	0.019783
TRIM63	0.019740
PEBP1	-0.019622
KCNC4	-0.019615
PRDX2	-0.019553
ASPH	0.019493
ICAM1	0.019434
GRPEL1	-0.019425
RPL26	-0.019388
DAB2	0.019292
CAPZA2	0.019286
ACSL1	-0.019214
XDH	0.019196
GRB10	0.019101
CACNA2D1	-0.018999
HSPA9	-0.018952
DDIT3	-0.018936
LCN2	0.018895
GNAI2	0.018802
NDUFB2	0.018611
SUB1	0.018586
DCAF6	0.018527
PDHA1	0.018519
ATP2A2	0.018494
KLF9	0.018440
FLOT1	0.018347
NDUFC2	-0.018343
HELZ	0.018294
RABAC1	0.018233
DBI	-0.018110
DECR1	-0.018065
CAV3	-0.017903
ARFGAP2	-0.017877
GAA	0.017831
RPL10	0.017810
MYADM	0.017802
JUP	0.017709
RPS26	0.017615
EGFL7	-0.017566
MAP1LC3A	-0.017533
BGN	-0.017452
BIN1	0.017363
TNFRSF1A	0.017227
AMPD1	0.017221
PSMB4	0.017158
SLC16A1	-0.017155
COL15A1	0.017032
CMC2	-0.016955
RALGDS	0.016933
PHB2	-0.016883
OAZ1	0.016881
PIK3CD	0.016865
BHLHE40	0.016796
PRKAR1A	-0.016766
TMEM255B	0.016687
TCTA	-0.016681
B4GALT6	0.016564
PSMC1	-0.016520
IQSEC1	0.016515
EIF4EBP1	0.016464
ARC	0.016457
RBBP7	-0.016393
HNRNPK	-0.016356
SYNGR2	-0.016298
YWHAZ	-0.016273
ORAI1	-0.016243
GPX3	-0.016214
CSF2RB	0.016213
G0S2	-0.016176
GAS6	0.016165
YWHAB	0.016124
SERPING1	0.016095
RPL8	-0.016058
PCNA	-0.016012
PSMB3	-0.015963
PSAP	0.015926
RPL23	-0.015894
UGDH	0.015835
UBR5	0.015803
PIM3	0.015799
CXCL10	0.015686
PSMC2	-0.015679
C1QB	0.015639
NDUFS1	-0.015620
NACA	0.015606
IL6	0.015604
GNG5	0.015587
CD14	0.015567
COL1A1	0.015539
UQCR11	0.015533
NCKAP1	-0.015529
RPL12	-0.015529
S100A9	0.015527
RPL35	-0.015333
GINM1	0.015283
TTC3	0.015278
MAPT	0.015275
AP4S1	0.015209
HNRNPC	0.015137
NFYC	0.015052
F2RL1	0.014988
HES1	-0.014982
RPS6	-0.014932
COX8A	-0.014818
STK10	0.014689
HMOX1	0.014614
TNK2	0.014490
PADI2	-0.014396
NDUFA6	-0.014346
PXN	0.014309
AP2M1	-0.014293
RPS7	-0.014291
PGK1	0.014274
CDC37	-0.014256
DNAJA2	-0.014239
KLHDC3	0.014231
PF4	-0.014218
APH1A	-0.014216
MXI1	0.014204
GNPAT	0.014172
HPX	0.014077
NPEPPS	0.014071
CUL2	-0.014057
SH2B2	-0.014046
ALDH7A1	0.014044
TRIM32	0.014032
DDX3X	0.014028
POMP	-0.014023
FKBP1A	-0.014022
PTPN1	0.014021
TMED2	-0.013924
P4HA1	0.013896
NUCB1	0.013875
TAF6	0.013865
METAP2	-0.013842
HSP90AB1	-0.013799
SLC35B1	-0.013780
NDUFAB1	0.013773
DACT2	-0.013770
SREBF1	-0.013755
OXR1	-0.013696
PFN1	-0.013620
C11orf73	0.013587
PECAM1	0.013586
ALAS1	-0.013562
KIF13A	0.013562
SPOP	0.013521
RPL18A	0.013442
RGCC	-0.013431
RAF1	0.013348
RALB	0.013343
ANGPT2	0.013308
SCHIP1	0.013265
CCDC117	0.013263
PNRC1	0.013198
CX3CL1	0.013153
CGRRF1	-0.013130
PAFAH1B1	-0.013104
COX1	0.013074
TNRC6B	0.013065
HSP90B1	0.013033
EIF4E2	-0.013024
PSMA4	-0.012995
VPS52	0.012981
KNG1	0.012918
NSFL1C	-0.012885
MDH1	0.012851
NEB	-0.012844
PSME2	0.012816
VEZF1	0.012809
PSMC4	-0.012790
ANXA2	-0.012774
TPT1	0.012749
RPS14	-0.012687
MTCH2	-0.012585
TRAPPC6B	0.012569
CALR	0.012496
H2AFX	0.012467
CD200	0.012451
PPIF	-0.012413
FBP2	-0.012380
RNPEP	0.012361
IGFBP5	0.012357
ANAPC5	0.012313
TMEM59	-0.012253
RHOA	-0.012167
ATP9B	-0.012136
VAMP3	-0.012059
EMB	-0.012038
JPH2	0.012009
TOMM20	-0.011971
NXF1	0.011965
UBE2G2	0.011954
PGM2	-0.011950
PCBP4	0.011949
MAOA	0.011930
KTI12	0.011923
CYBA	0.011898
CXXC5	0.011871
MAP3K12	-0.011869
QDPR	-0.011801
AES	0.011797
RHOJ	0.011778