!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	rat
!drug_name	Methylprednisolone
!smiles	CC1CC2C3CCC(C3(CC(C2C4(C1=CC(=O)C=C4)C)O)C)(C(=O)CO)O
!drugbank_id	DB00959
!pubchem_cid	6741
!cell_type	Skeletal muscle - 2 Hour
!organism	rat
!end_metadata
MGP	0.269382
GLUL	0.194856
RHOB	0.186869
TSC22D1	0.185810
NFKBIA	0.176422
MYH7	0.166248
COX2	-0.163632
ZFP36	0.155766
HSPB6	-0.142199
MYL3	0.138251
CEBPB	0.131992
CRYAB	-0.124520
TRIM63	0.115427
COL1A2	0.113292
NDUFS7	0.112314
TXNIP	0.109839
PDK4	0.100978
IFITM3	0.099952
HSPA8	0.096018
LITAF	0.095601
RRAD	0.095007
MYH6	0.092096
JUNB	0.089963
ERRFI1	0.089855
ACTN2	0.087474
DYNLL1	-0.083367
COX3	-0.082706
ND2	-0.080872
NR4A1	0.079642
PYGM	0.078243
LCN2	0.077588
TNNI2	-0.075542
XDH	0.074351
COL1A1	0.072513
CASQ1	-0.069937
AQP1	0.069251
MYF6	-0.068697
MDH1	-0.067733
H19	-0.066286
NDUFB3	-0.066193
RPS17	-0.065906
AK1	-0.065022
FTH1	0.063666
TCAP	0.063290
COL3A1	0.063285
ATP2A1	0.063254
CEBPD	0.062813
MYL12B	-0.061478
RPL39	-0.060890
COX5A	0.060043
ATP5B	0.059682
RPL15	0.058825
G0S2	-0.058796
PDLIM1	0.058251
SGK1	0.057833
FTL	-0.055503
CYTB	-0.055321
MGST3	-0.055237
ENO3	-0.053392
HSP90AB1	0.053352
ACTC1	-0.053280
ND4	-0.052877
SDCBP	0.052795
TUBA4A	-0.052650
PPP2R5A	0.052228
AKAP12	0.051729
FXYD1	-0.051608
CDC42EP3	0.051083
MYL2	-0.050928
CHRNA1	-0.050917
ND1	0.050113
NDUFA3	-0.049904
ND5	-0.049677
MYBPC1	0.049506
MYOD1	-0.048922
RPS25	-0.048858
CSRP3	-0.048856
TUBA1B	-0.048075
RPL23	0.047878
TMA7	-0.047380
JUN	-0.047084
POSTN	-0.046722
COX7B	-0.046578
PSMD11	0.045819
TFRC	-0.045583
TMOD1	0.045409
EIF4EBP1	0.045073
RPS27L	-0.045018
ACADL	0.044335
PSMB5	-0.044217
CKM	0.044206
ARF1	-0.043471
GPX1	-0.043353
ATP5F1	-0.043280
NR1D1	-0.043121
KLF9	0.042995
PABPC4	0.042688
LPL	0.042634
EEF1A2	-0.042310
RPL26	-0.041861
ACTA1	-0.041830
NFKB1	0.041725
NDUFA4	0.041508
PPIA	-0.041279
ATP5J	-0.041267
DES	-0.041003
SPRY1	0.040028
PSMB4	0.039612
TIMM23	-0.039534
CYC1	-0.039497
ATP5H	-0.039080
PFN1	-0.038631
PGAM2	-0.038242
CS	-0.038101
RPLP2	-0.038086
VDAC1	-0.037288
MGST2	0.037132
ANGPT2	0.036864
ATP5D	-0.036836
PTP4A2	-0.036472
LDHB	-0.036323
RPLP0	-0.036189
MPC1	-0.036072
CNBP	-0.036047
CLU	0.035994
IRF1	0.035854
BIN1	-0.035790
GNAI3	0.035787
ACTG1	-0.035710
CAPNS1	-0.035638
PPP1CB	0.035551
MYBPC2	0.035318
PAICS	0.035301
RPS10	-0.035077
ATP5O	0.034935
SMPX	-0.034909
SVIL	0.034907
LGALS1	-0.034698
EEF2	-0.034649
TIMM17A	-0.034251
CCNL1	0.033991
MYBPH	-0.033900
B4GALT6	0.033819
RPL27	-0.033743
GABARAP	-0.033696
CSDE1	-0.033596
RPL3L	-0.033510
IGF2	0.033325
RPS8	-0.033098
SNRPB	-0.033033
AHNAK	0.032871
SDC4	0.032844
MYH2	0.032716
PPP1CA	-0.032649
MRFAP1	0.032605
GOT1	-0.032551
RPS12	0.032491
CXCL2	0.032444
LAMTOR1	-0.032411
PGM2	-0.032334
AKR1A1	-0.031687
ENO1	-0.031630
CCNG1	0.031610
LUM	-0.031556
GSTA5	0.031483
KLHL41	-0.031477
RPSA	-0.031437
CNN3	0.031427
PFKM	-0.031367
MAP1LC3B	0.031251
NAPA	0.031042
TUBA1C	0.030946
SLC16A3	-0.030810
SQSTM1	0.030718
UQCRC2	-0.030698
ICAM1	0.030287
MAPK14	0.030076
SCN1B	0.030051
SLC3A2	0.029972
TRIM54	0.029890
SDHAF2	-0.029691
ADM	0.029617
ID3	-0.029192
MAP1LC3A	-0.028817
SPARCL1	0.028770
PARK7	-0.028570
RPL28	-0.028349
GADD45A	0.028341
MYADM	-0.028338
PECAM1	0.028275
RPL17	0.028178
RAB5B	-0.027861
ARL4A	0.027787
IGFBP3	0.027660
RPL19	0.027594
RPL18	-0.027489
ATP1B1	-0.027367
CACNG1	-0.027350
SELP	0.027225
NDUFB6	-0.027071
TJP1	-0.027049
HADHB	-0.026953
PTP4A1	-0.026815
RPS15	-0.026746
GPD1	-0.026610
NEXN	-0.026550
MYLK2	-0.026546
SOCS3	0.026333
STK10	0.026316
CITED2	-0.026315
TECR	-0.026073
RPL12	0.026021
RPL7A	-0.025965
ANKRD1	-0.025919
EMP1	-0.025813
ZFP36L1	-0.025810
LYVE1	0.025452
LAMC1	0.025386
NDUFC1	-0.025362
UCP3	0.025226
MYC	0.025116
NDUFV2	0.025066
PDK2	-0.025015
EEF1G	-0.024992
ACTA2	-0.024918
FAU	-0.024901
AP2M1	-0.024885
TMEM59	-0.024760
AMPD1	0.024722
RPL4	-0.024664
F2R	0.024614
CKMT2	-0.024508
MDH2	0.024501
RPL13A	-0.024380
B2M	0.024376
ADCY2	0.024351
APOE	-0.024089
FOS	-0.024074
PSMA7	0.024068
NDUFB11	-0.024065
YWHAG	-0.024039
SLC25A3	-0.023973
SLC25A4	0.023973
CD14	0.023898
GAS6	0.023864
PEBP1	-0.023821
CISH	0.023805
PSMA6	0.023578
GRB10	0.023515
COX6A1	-0.023502
CBFB	-0.023405
MYL4	-0.023314
ORAI1	-0.023302
CTSS	0.023208
TCP11L2	0.023208
EGR1	-0.023143
FLOT1	-0.023099
FIS1	-0.023026
RPS9	-0.022971
DBI	-0.022786
PIM3	0.022663
KLHDC3	0.022482
DBP	-0.022433
CYCS	-0.022362
DDX3X	0.022344
WIPF3	0.022304
SYNGR2	-0.022216
IDH2	-0.022194
SLC41A3	0.022194
MEOX2	-0.022157
UBXN1	-0.022153
NME2	0.021994
NDUFS8	-0.021948
RPS14	-0.021843
PRDX2	0.021812
DUSP1	-0.021682
RPS15A	-0.021634
MYCBP2	0.021591
NEU2	-0.021584
RPL10	-0.021447
NEK7	0.021353
RPS27A	-0.021323
PTPN1	0.021234
PXN	0.021220
MMP14	-0.021100
RPL22	0.021083
PRDX3	-0.021070
CA3	0.021060
DAB2	0.021028
RPS5	0.020939
TRIM8	-0.020916
YBX1	0.020866
CXCL10	0.020703
CUTA	-0.020686
SLC25A5	0.020558
S100A8	0.020436
MYOG	-0.020394
VEZF1	-0.020383
CDC37	-0.020266
CXXC5	-0.020205
NRARP	-0.020182
MAPK6	-0.020173
BTG1	0.020074
CPT2	0.020015
PPARD	0.019898
PNRC2	-0.019871
ANAPC5	0.019854
LDHA	0.019844
NDUFA6	-0.019680
SERBP1	-0.019676
CST3	0.019492
CTSD	-0.019484
DNAJA4	-0.019469
MORF4L2	-0.019439
SLC2A4	-0.019318
CYP27A1	0.019040
DDIT3	-0.019033
NDUFB5	-0.018944
MFGE8	-0.018842
PDE4B	0.018746
DACT2	-0.018677
CD151	-0.018624
COX8A	-0.018585
TSPAN8	0.018456
EGFL7	-0.018357
DNAJA3	-0.018296
ZNRF1	0.018184
HSP90AA1	0.018166
RPL37	-0.018081
RPS11	0.018034
HUWE1	0.018011
DLAT	-0.018009
EFNA1	-0.017992
EIF4A2	0.017943
ACAT1	0.017862
RPL36AL	-0.017847
CTSV	-0.017811
CLCN1	-0.017809
UGDH	0.017674
PSMD2	-0.017601
DLK1	-0.017592
NRP1	-0.017552
MYL9	-0.017549
SUCLG1	-0.017374
GNAS	0.017324
TOMM20	-0.017220
HIBADH	-0.017090
CD63	-0.017059
SOD1	-0.017050
ASPH	-0.016921
NUDT4	-0.016872
CDC34	-0.016869
UBC	-0.016802
DNAJA2	0.016758
TIMP1	0.016626
ASB2	0.016624
PDHB	-0.016606
LGALS3	0.016496
ACADM	-0.016491
P2RY2	-0.016455
RPS29	0.016423
LMNA	-0.016371
SLC28A2	0.016194
NDUFV3	-0.016150
HMOX1	0.016125
IFNGR1	0.016109
UQCR11	0.016053
S100A9	0.015998
EIF5B	0.015961
CPT1A	-0.015945
TTC3	0.015914
SERPING1	0.015907
FABP5	-0.015881
PSMC3	-0.015865
ACADVL	-0.015779
RHOA	-0.015777
PLA1A	0.015728
DDR1	-0.015685
SMIM12	-0.015679
H1F0	-0.015671
PGK1	-0.015658
KLF10	-0.015561
FABP3	-0.015560
CNKSR3	0.015477
TXNRD1	0.015470
DCAF6	-0.015419
COA5	-0.015378
HRAS	0.015364
CD81	-0.015303
CHRNB1	-0.015275
RAB11B	-0.015272
MAP3K12	-0.015267
COX7A2	-0.015261
SREBF1	-0.015259
ALAS1	-0.015254
NUTF2	-0.015251
RPS13	-0.015235
LTA4H	-0.015226
NOL3	-0.015121
TUBB	-0.015071
DNAJA1	0.015036
ACKR3	0.015007
ALDOA	0.014933
CHAD	0.014929
IMP3	0.014920
HK2	0.014901
CYTH2	-0.014883
PROS1	0.014873
PPM1A	-0.014870
PVALB	0.014822
ATP2A2	0.014784
IRS1	-0.014776
MYL12A	-0.014774
EIF3D	0.014768
PLAGL1	0.014763
MAZ	-0.014693
ATP6AP1	-0.014685
APH1A	-0.014682
RPS16	-0.014665
LOXL1	-0.014662
RPS6	0.014630
SLC16A1	-0.014580
DAPK2	-0.014490
SIRT2	-0.014475
MSTN	0.014458
ID1	-0.014453
SEPP1	-0.014419
S100A10	0.014341
CCND3	-0.014272
NOP58	0.014259
CPA1	-0.014247
HP	0.014197
PDIA6	0.014182
GNG5	-0.014161
TRIOBP	-0.014122
PSME2	0.014102
EIF2S3	-0.014101
THBS4	-0.014092
CSNK1D	0.014059
CLEC10A	0.014031
RPL30	0.013985
RBFOX2	0.013968
HNRNPAB	0.013926
GAPDH	0.013847
ECE1	0.013825
PSAP	-0.013817
PAWR	0.013720
PGM5	0.013713
CTDSP1	-0.013712
BGN	-0.013707
PF4	-0.013668
COX1	-0.013580
TUFM	0.013579
VIM	-0.013573
TNFRSF1A	0.013563
ATP1B3	0.013553
CPT1B	-0.013527
PMEPA1	-0.013502
AUH	0.013491
EPN1	-0.013486
ADRB2	0.013460
CRISPLD2	0.013403
CTBP1	0.013378
GPD2	0.013369
RAB10	-0.013348
BECN1	-0.013261
F2RL1	0.013178
PLEC	0.013107
CA4	-0.013065
ATP9B	-0.013052
SNN	-0.013026
VEGFB	-0.013015
NCL	0.012958
CYHR1	-0.012946
GRN	-0.012928
NDUFC2	-0.012913
SH3KBP1	-0.012856
ACAA2	-0.012846
COX4I2	-0.012835
DLST	-0.012829
S100A4	-0.012809
MAPK3	-0.012797
GRINA	0.012702
ATP5G1	-0.012689
NDUFB10	0.012673
CFD	-0.012651
SOD2	0.012633
RGCC	0.012615
VCP	0.012606
SDHA	-0.012569
KCNC4	-0.012545
ALDH6A1	0.012457
FBXW5	-0.012451
RNH1	-0.012444
RARA	-0.012402
MGLL	-0.012390
CACNA2D1	0.012382
MYLPF	0.012356
PNOC	0.012265
YWHAZ	0.012234