!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!organism	Homo sapiens
!cell_type	MCF7cells
!pert_name	estrogen
!pert_id	CHEBI:50114
!organism	human
!pert_type	chemical
!end_metadata
RARA	0.081738
GREB1	0.074504
MYB	0.071977
IGFBP4	0.071149
HEY2	0.069470
HSPB8	0.069160
MYC	0.067834
PEX11A	0.065772
TSKU	0.064522
SLC22A5	0.062368
GPR68	0.059321
STC2	0.057791
RAPGEFL1	0.057396
CCDC88C	0.056369
CASP7	0.052263
MYC	0.051507
CA12	0.049538
RASGRP1	0.049156
NAV2	0.046983
ARID5B	-0.046667
MICB	0.043089
KCNK6	0.043069
MAP6D1	0.041792
SIAH2	0.041776
RET	0.041176
FAM102A	0.040831
FAM102A	0.040713
SFXN2	0.040664
KRT13	0.039879
TPD52L1	0.038504
SLC9A3R1	0.036767
SLC7A5	0.035879
SLC25A24	0.035510
NAV2	0.035276
FJX1	0.035153
C10orf2	0.035087
CCND1	0.035041
PKIB	0.035033
PGR	0.034899
FGD3	0.034282
B3GALNT1	0.034095
TPD52L1	0.034041
CASP7	0.033570
CA12	0.033394
SALL4	-0.033216
DDX10	0.032983
CYP1A2	-0.032505
FOXC1	0.032116
SVIL	0.032074
NOP16	0.032021
PHLDA1	0.031814
ASCL2	0.031794
ADAMTS9	0.031527
NOP16	0.031343
NXT1	0.031327
ITPK1	0.031179
EGLN2	0.031130
B3GALNT1	0.031057
SIPA1L2	-0.030755
BMF	-0.030746
B3GALNT1	0.030545
GRHL3	-0.030545
DEPTOR	0.030526
SYT12	0.030241
DEPTOR	0.029913
ALDH1A3	-0.029674
CCNG2	-0.029606
ADCY9	0.029533
P2RY2	0.029369
DDX21	0.029253
CLDN23	0.029122
PDXP	0.029061
HEY1	-0.029037
PFKFB3	0.028930
MBOAT1	0.028749
ALDH1A3	-0.028677
ROCK2	-0.028437
LRIG1	0.028382
TMEM2	0.028330
CXCL12	0.028085
SLC2A1	0.027821
ST3GAL1	-0.027728
ASB13	0.027715
SLC25A19	0.027557
FKBP4	0.027462
SNHG15	0.027301
SNHG15	0.027133
MARS2	0.026997
ABAT	0.026835
GINS3	0.026824
IRX2	0.026778
GALNT4	0.026756
RRS1	0.026454
NBPF22P	0.026386
GEMIN4	0.026359
HECW2	-0.026285
STARD13	0.026241
GDF15	0.026053
TNFRSF11B	-0.025961
SEC14L2	0.025944
LRIG1	0.025941
ST3GAL1	-0.025894
RLN2	0.025885
BIRC3	0.025883
PPRC1	0.025877
WWC1	0.025780
GAB2	0.025760
NRIP1	0.025742
GADD45B	0.025517
TGIF2	0.025358
TLE1	-0.025265
NCOR2	0.025157
DKK1	0.024889
SOCS2	-0.024747
HIVEP1	-0.024716
PLOD2	0.024631
RCL1	0.024558
B3GALNT1	0.024471
MAPT	0.024407
TFAP2A	-0.024407
SGK223	0.024341
BANP	0.024312
CXXC5	0.024227
ADORA1	0.024053
KLF10	0.024002
DOK7	0.023942
FAM217B	-0.023873
CDKN2B	-0.023820
THOC5	0.023817
SGK3	0.023780
EPB41L5	-0.023758
PUS1	0.023745
VPS9D1-AS1	0.023484
FILIP1L	-0.023432
BMF	-0.023348
ST8SIA4	-0.022993
DAB2	-0.022927
CREBRF	-0.022925
SBNO2	0.022829
KITLG	-0.022822
KHNYN	-0.022817
ANKRD50	-0.022747
EPB41L5	-0.022594
LAMA3	0.022562
NCOR2	0.022457
SLITRK6	-0.022409
ULK1	0.022359
ZNF696	0.022319
CARD10	0.022319
FLNB	0.022254
RAB30	0.022110
KITLG	-0.022108
BYSL	0.022066
EGLN2	0.022029
ZMYND19	0.022015
SH3BP4	-0.021850
SOCS2	-0.021805
AMD1	0.021673
ABCC5	-0.021628
MEGF9	-0.021589
C1QTNF6	0.021560
LYAR	0.021440
ZNF239	0.021436
KCNK6	0.021361
HCAR1	-0.021348
PIK3R1	0.021317
SLC29A1	0.021272
KIAA1211L	-0.021197
LAMA3	0.021149
S1PR3	-0.021122
WDR72	0.021084
SLC20A1	0.021083
TRIM8	0.021010
AP1B1	0.020999
CDC25A	0.020982
JARID2	0.020968
FLRT3	-0.020942
TIPARP	0.020927
EPCAM	-0.020839
FOS	0.020779
SLC25A25	0.020743
IL17RB	0.020701
GEMIN5	0.020672
RERG	0.020625
BBX	-0.020588
UCK2	0.020495
AEN	0.020479
FILIP1L	-0.020462
SNHG1	0.020455
NXNL2	0.020448
SLC25A42	0.020446
LYAR	0.020422
GRB14	-0.020409
WDR4	0.020388
LINC00936	-0.020372
FAM212B	0.020345
IER3	0.020263
COBLL1	-0.020192
PUS7	0.020184
TP53INP1	-0.020144
RPS6KA2	0.020140
NOP2	0.020066
RCAN1	-0.019887
ADAMTSL5	0.019800
WDFY2	-0.019772
POC1B	0.019745
C8orf37	-0.019723
BOP1	0.019639
AMMECR1	0.019627
SURF6	0.019618
MPPED2	0.019609
THOC5	0.019601
ZNF485	0.019583
CCDC86	0.019550
PLEKHF2	-0.019515
FAM175A	-0.019454
BAG3	0.019416
RRP12	0.019414
MESP1	0.019400
CXXC5	0.019383
NIPBL	-0.019356
FAM216A	0.019327
DKC1	0.019314
MREG	0.019243
SGK223	0.019227
QTRTD1	0.019208
CIART	0.019204
CTPS1	0.019170
POLR1C	0.019113
HS3ST3A1	0.019037
MEIS2	-0.019003
TIGD5	0.019000
C16orf74	0.018951
NIFK	0.018929
FOXN3	-0.018922
TTF2	0.018890
TMEM45B	-0.018876
ACKR3	-0.018787
FAIM3	0.018785
ECE2	0.018780
FGFRL1	0.018772
PMAIP1	0.018772
TRIM47	0.018721
RNF144A	0.018697
BOD1	0.018695
RPLP1	-0.018648
ZBED2	-0.018645
PPAT	0.018569
GPATCH4	0.018527
HNRNPU	-0.018519
MEGF6	-0.018495
GOLGB1	-0.018457
CISH	0.018450
NOP2	0.018447
UBLCP1	-0.018437
SS18	-0.018425
TP53INP1	-0.018423
GCNT1	-0.018372
AEN	0.018354
ULK1	0.018346
CDC42EP1	0.018331
NIP7	0.018289
NABP1	0.018267
RNF144B	-0.018241
FAM102A	0.018228
SNAPC4	0.018226
ZNRF3	0.018211
KCNF1	0.018200
DAB2	-0.018167
SNHG17	0.018158
SYCP2	-0.018134
SHISA2	-0.018121
AXIN1	0.018067
SRSF7	0.017967
PRKCD	0.017938
ECE2	0.017914
NOC3L	0.017909
PLD6	0.017899
QSOX2	0.017879
SNORA70	0.017838
ADM	0.017833
GRHL3	-0.017815
RAB27B	-0.017814
MRPS12	0.017771
SNORD31	0.017764
TMTC2	-0.017762
NRP1	-0.017701
BRIX1	0.017673
PVRL3	-0.017670
FAM60A	0.017667
CDCA4	0.017665
SLC7A6	0.017652
AP1S2	0.017645
MYCBP2	-0.017586
DPH2	0.017565
BRIX1	0.017551
CLIP1	-0.017539
PTPN13	-0.017538
CDT1	0.017529
CITED2	-0.017503
RBMS1	-0.017503
MED13L	0.017489
CHCHD4	0.017478
KIAA1211L	-0.017473
SOX2	-0.017469
ARL4A	-0.017456
EXOSC5	0.017451
OR5V1	-0.017406
DHX37	0.017396
PLEKHA6	0.017364
ERRFI1	0.017363
RPL13	0.017357
SLC25A15	0.017355
COLEC12	0.017353
DDX31	0.017325
TACC1	-0.017314
MIR564	-0.017301
CEACAM1	-0.017296
PDCD2L	0.017261
NUP35	0.017256
SNORA67	0.017246
RAB31	0.017232
TFPI	-0.017219
ABCE1	0.017192
MYEOV	0.017189
BRICD5	0.017185
GFOD1	0.017176
BLZF1	-0.017141
A4GALT	0.017092
CHD6	-0.017091
CDCA7	0.017086
PDGFB	0.017082
ZNF26	0.017077
LTV1	0.017075
COA7	0.017047
RCC1	0.017042
NOP2	0.017025
HIATL2	-0.016998
MXD1	0.016990
SLC38A2	0.016969
NIPBL	-0.016958
PMP22	-0.016942
CENPA	0.016931
FKBP14	-0.016931
ZSWIM6	0.016876
KLF10	0.016836
CLDN9	-0.016824
KLHL5	-0.016806
LOC100128288	-0.016785
SNTB2	-0.016740
PCNT	0.016733
GPATCH2	-0.016721
MAGI1	0.016716
CA2	0.016684
PRKCH	-0.016674
CASP6	-0.016660
FGF1	-0.016657
LRP12	-0.016654
CYR61	0.016648
ST8SIA4	-0.016646
CXCL12	0.016636
ENC1	-0.016622
EAPP	-0.016605
SH3RF1	-0.016605
PPAN	0.016588
PTGER4	-0.016578
SUMF2	-0.016565
CYP1A1	-0.016548
RUNX1T1	-0.016540
SYCP2	-0.016518
RBM24	0.016518
CHPT1	0.016483
ST8SIA4	-0.016480
SLC35E1	-0.016478
SDCCAG3	0.016471
SGK1	0.016469
PVRL3	-0.016467
ZNF14	-0.016453
PPP3CA	-0.016452
TMEM64	0.016442
CEBPB	0.016434
ATRIP	0.016392
SS18L1	0.016385
POGLUT1	0.016382
CIRH1A	0.016367
MAK16	0.016365
SLC22A23	-0.016337
POLR1C	0.016316
SLC35F2	0.016296
UGCG	0.016295
RBFOX2	-0.016266
EPT1	0.016250
GSTTP2	0.016223
DDX55	0.016214
PCDH11Y	0.016193
TRIP11	-0.016173
KCNK5	0.016154
WDR12	0.016136
CYP4F22	0.016122
WDR12	0.016116
SNORA16B	-0.016116
TNFAIP8	-0.016083
MBLAC2	0.016056
SLC37A3	0.016051
ZNF529	0.016050
PNP	0.016042
TFRC	0.016039
NAV2	0.016034
RPIA	0.016029
NDUFAF4	0.016026
ALAD	0.016026
MTFP1	0.016005
MYOF	0.016004
PNO1	0.015980
COL18A1	0.015978
MIR642A	-0.015940
FAM214A	-0.015939
LRRFIP1	-0.015939
SLC29A1	0.015930
SPTLC1	-0.015923
MIR587	0.015887
ADCK3	0.015881
TLE4	-0.015873
SAC3D1	0.015868
ZNF91	-0.015865
KLHL21	0.015864
SCARNA9L	0.015835
EPS15L1	0.015831
ARHGEF18	0.015824
UVRAG	-0.015816
CSTF1	-0.015810
ARHGAP12	-0.015806
BTG1	-0.015793
KBTBD11	-0.015784
PPFIBP2	-0.015708
PDS5B	-0.015699
XPO5	0.015687
FXYD2	-0.015679
PARP8	-0.015658
FCAR	-0.015642
LEO1	-0.015622
PRR5	0.015619
KLF4	0.015597
HINT3	-0.015593
POLR2D	0.015588
QRFPR	-0.015567
SCN10A	0.015564
CAV1	0.015544
C19orf48	0.015517
RHPN2	0.015510
XBP1	0.015498
ACVR1	-0.015492
CYP4F8	0.015472
SGK3	0.015471
BMS1P5	-0.015461
TBC1D32	-0.015451
ERCC6L2	-0.015435
LYPD6B	-0.015434
CTSK	-0.015429
RPF2	0.015428
JADE2	0.015423
TIPIN	0.015422
PSD3	-0.015412
SLC25A28	0.015400
PLEKHH1	0.015391
GRWD1	0.015389
MCCC1	-0.015385
ZMIZ1	0.015381
CCNG2	-0.015379
TFPI	-0.015373
CDKN2B	-0.015367
VGLL4	-0.015356
FUT7	0.015354
CSTF3	0.015333
KIAA0020	0.015321
DIP2B	-0.015318
NR5A2	0.015314
SLC35F6	0.015297
ASPHD1	0.015285
SCNN1A	0.015270
GPATCH4	0.015270
CBFA2T3	0.015268
CREB3L2	-0.015246
GEMIN6	0.015238
RBMS1	-0.015235
MSX2	-0.015232
C4orf3	-0.015231
KCTD18	-0.015226
VEGFC	-0.015208
ZNF217	-0.015206
RASD1	-0.015194
TFAP2A	-0.015187
RTN3	-0.015161
RHBDF2	0.015159
MIR25	0.015149
PRMT5	0.015149
SUV420H1	-0.015145
GABARAPL2	-0.015134
MAGEB4	-0.015122
ASB6	0.015117