!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	BPDE
!smiles	C1=CC2=C3C(=C1)C=CC4=C3C(=CC5=C4C6C(O6)C(C5O)O)C=C2
!pubchem_cid	41322
!cell_type	WI-38  Lung fibroblasts - 0.1uM
!organism	human
!end_metadata
TIMP1	-0.185092
COX1	0.172903
LDHA	-0.146024
GREM1	-0.145726
SERPINB2	0.145047
TUBA1A	0.142852
RPL36A	-0.137392
MMP1	0.128723
IGFBP3	-0.122639
LGALS1	0.118464
RND3	0.115822
TUBB	-0.109859
RPL3	-0.102526
H2AFZ	-0.099336
HMGN2	-0.098387
COL1A2	-0.096148
UBC	0.094122
RPL39	0.093164
TUBA1B	-0.092581
TMEM158	-0.088669
SERPINH1	-0.087633
MIF	-0.087340
NGFRAP1	0.082577
PFN1	-0.081678
LAPTM4A	0.079704
TUBA1C	-0.077569
TUBB4B	-0.075967
LOX	-0.074289
GARS	-0.072800
PRDX1	0.072039
IRF2BPL	0.071470
SERPINE1	-0.070508
CALM2	0.070283
RPL22L1	-0.070260
MYL6	0.070123
TGFBI	-0.069716
RPS19	0.069499
COL1A1	-0.069003
ANP32B	-0.068772
TMSB10	0.067671
TUBB2A	0.067294
RRM2	-0.067186
RPL12	-0.067080
PTTG1	-0.066521
GPX1	0.066296
RPS5	0.065655
FTH1	-0.064894
KPNA2	-0.064737
PSAT1	-0.064030
TPI1	-0.063933
HEXB	0.063786
COL3A1	-0.063069
SERINC1	0.062681
ERRFI1	-0.062664
CDKN1A	0.062337
COX2	0.062203
BNIP3	-0.061958
ATP6	0.061813
COL6A3	-0.061611
ENO1	-0.061341
DCN	0.061150
IGFBP4	-0.060747
STOM	0.060243
UBE2S	-0.060061
UBB	0.060021
RPL19	-0.059697
B2M	0.059664
FTL	0.059021
RPS3	-0.058754
MEST	0.058587
FN1	-0.057994
EEF1B2	-0.057986
SLC25A6	-0.057858
DDIT4	-0.057833
CCNG1	0.056884
MTCH1	0.056514
NPM1	-0.055515
NPTN	0.054968
ATF4	-0.053803
MAGED1	0.053716
VIM	-0.053240
TAX1BP3	0.052165
COL4A2	-0.051609
SRP14	0.051487
USMG5	0.050683
CKS2	-0.050602
TUBB3	-0.050383
SLC25A5	-0.050306
CD59	0.050051
RAN	-0.049897
S100A4	0.048694
RPL29	0.048551
ARL6IP5	0.048528
LDHB	-0.048014
ALDOA	-0.047803
RPL32	-0.047748
ISCU	0.047650
RPL4	-0.046604
RPS27L	0.046072
ANXA2	0.045835
COL6A2	-0.045609
CTSC	0.045372
RPL36	-0.044618
ANLN	-0.044034
EIF4A1	-0.042924
SLC38A2	0.042818
ARL6IP1	-0.042682
PRC1	-0.042495
MYL12B	0.042164
PTGES3	-0.041900
SNHG16	-0.041661
HIST1H2BK	0.041150
NPTX1	0.041095
LRP11	0.040957
CDK2AP1	0.040840
ITM2B	0.040627
TM4SF1	0.040329
TRAM1	0.040158
BTBD3	0.040012
PLS3	0.039908
RPS3A	0.039855
TRPA1	0.039578
MORF4L1	0.039516
LOXL1	-0.039439
GNG11	0.039432
PKM	-0.039229
TMA7	0.038819
PDLIM1	0.038712
ACTG1	0.038538
SNRPG	-0.038001
SH3BGRL3	-0.037960
TIMP3	-0.037942
NDUFA4	0.037846
TPX2	-0.037833
UBE2C	-0.037636
RPL10A	-0.037271
CEMIP	-0.037204
RPL14	-0.037112
AK3	0.037109
EDIL3	0.037108
CTSB	0.036800
PTTG1IP	0.036798
QSOX1	-0.036628
IGFBP7	0.036547
DSTN	0.036245
PSMB3	0.036116
MRPL3	-0.036048
RPS17	-0.035999
WBP5	0.035635
RPS15	0.035396
EIF3E	-0.035129
ZFAS1	-0.034997
PLAT	-0.034609
EIF1	-0.034597
PGK1	-0.034585
EIF2S2	-0.034576
ASNS	-0.034330
NXN	0.034299
P4HB	-0.034186
ATP6V0E1	0.034135
GAPDH	-0.033948
MRFAP1	0.033864
PTMA	-0.033607
CNN3	0.033428
TAGLN2	-0.033321
CDC20	-0.032900
DKK3	0.032871
NABP1	0.032794
C12orf75	0.032698
FOXF1	0.032580
ND2	0.032544
VCAM1	-0.032373
MYL12A	0.032349
SLC7A5	-0.032234
PSMD2	0.032196
YBX1	-0.032080
TMEM35	0.032005
TNC	-0.031815
SEC13	-0.031654
FRMD6	0.031531
CDC42EP3	0.031388
TPM4	-0.031202
DDX5	0.031184
NCOA4	0.031117
FBL	-0.031068
WLS	0.030991
HSPD1	-0.030978
DYNLT3	0.030859
RPS11	0.030796
HMGB2	-0.030790
EFEMP1	-0.030662
RPL9	0.030543
LOXL2	-0.030534
GAS6	0.030490
SPON2	-0.030476
CCNB1	-0.030401
SRM	-0.030311
CKAP4	0.030264
TRIM22	0.029720
ODC1	-0.029718
ATP6V1A	0.029677
RPLP0	-0.029407
KIAA0101	-0.029382
RPS20	-0.029379
CD63	0.029159
SERPINE2	0.028908
HIST1H2AC	0.028775
MRPL36	0.028754
EIF4EBP1	-0.028698
LPAR1	0.028592
S100A13	0.028383
DYNC1I2	0.028306
RPS8	-0.028305
TMEM258	-0.028292
NDUFA13	0.028258
CCL2	-0.028054
PVRL3	0.027777
CHCHD2	-0.027753
NACA	-0.027700
GNG5	-0.027654
RPS18	-0.027571
HMGB1	-0.027506
RPL21	-0.027403
FLNA	-0.027402
RPLP2	-0.027227
RPL5	-0.027211
GLIPR1	0.027105
MTHFD2	-0.026957
HNRNPAB	-0.026867
ADAM9	0.026812
EEF1A1	0.026681
NSA2	-0.026629
ARPC2	0.026439
TRIM28	-0.026289
TUBB6	-0.026261
PBK	-0.026113
RTN4	0.026087
TIPARP	0.026087
LAMP1	0.026072
PARK7	0.025946
SMURF2	0.025909
SHC1	0.025859
NEXN	0.025657
TMEM59	0.025628
PHB2	-0.025556
CKS1B	-0.025501
SEP15	0.025448
TNFRSF11B	0.025305
PCDH18	0.025247
SPARC	0.025152
TFRC	-0.025098
COX7A2	0.025071
MAFF	0.025005
TRHDE	0.024911
PTP4A2	-0.024907
GNG10	0.024833
SLIRP	-0.024821
LRRN3	0.024724
OAZ1	0.024714
CAPNS1	-0.024633
PTRF	-0.024577
HSP90AA1	-0.024565
ADD3	0.024522
CALD1	0.024510
ITGA2	0.024478
P4HA1	-0.024460
HSBP1	0.024392
ARPC1A	-0.024312
RPS26	0.024159
H3F3B	-0.024080
ACTR3	0.024061
CAPN2	0.024046
RAB1A	0.024002
HLA-A	0.023814
CENPW	-0.023740
CFL1	0.023657
ITGAV	0.023619
ITGA5	-0.023588
SERPINB7	0.023583
VDAC2	-0.023477
MT1E	0.023213
SRPX	0.023019
BCAT1	-0.023006
TCEB2	0.022928
NARS	-0.022896
HMMR	-0.022884
LASP1	0.022873
NDUFA12	0.022839
CRIM1	0.022830
RPS12	-0.022770
CHMP5	0.022568
CLU	0.022460
COX6B1	0.022459
TPT1	0.022424
PSMB4	0.022414
TP53I3	0.022377
MFSD1	0.022343
TMEM123	0.022132
AXL	0.022128
CDK4	-0.022073
PRDX6	0.022011
ISG15	0.022002
TWSG1	0.021943
RACGAP1	-0.021887
RPL30	-0.021765
APEX1	-0.021715
SLC1A5	-0.021631
RPL8	-0.021590
CS	-0.021400
NFE2L2	0.021397
PLP2	-0.021308
GAS5	-0.021263
FABP5	-0.021241
ATP6V0D1	0.021199
AHRR	0.021171
SRSF2	-0.021161
CTSK	0.021139
HSPA1A	0.021092
PRSS23	0.021081
CDKN3	-0.021070
CHAC1	-0.021018
WRB	0.021015
SNHG1	-0.020935
PLK2	0.020895
TMEM263	0.020869
SOD1	0.020866
CTGF	0.020811
PFKP	-0.020805
COMMD8	0.020801
KIF20A	-0.020695
NEAT1	0.020676
GTF3C6	0.020661
NDRG1	-0.020641
YWHAB	0.020636
GSTO1	-0.020628
ATP5L	0.020625
MAD2L1	-0.020613
ANXA2P2	0.020571
TFPI2	-0.020492
NNMT	-0.020471
PHGDH	-0.020462
GPI	-0.020414
DNAJA1	0.020371
PGAM1	-0.020362
HIGD1A	0.020296
CAV2	0.020232
SNHG8	-0.020209
NDUFAB1	0.020185
POSTN	-0.020115
SH3BGRL	0.020075
DLGAP5	-0.020034
CNN2	-0.020014
PXDN	-0.020000
GBP3	0.019990
TXNIP	-0.019967
HSPE1	-0.019946
UHRF1	-0.019934
PRR11	-0.019880
TYMS	-0.019878
SPCS1	0.019811
COPRS	-0.019765
HMGA1	-0.019739
KRTAP1-5	0.019732
FOXD1	-0.019727
PAICS	-0.019560
RNF11	0.019530
RPS10	-0.019523
MIR22HG	0.019381
S100A16	-0.019347
SEC31A	0.019222
SERF2	0.019187
EID1	0.019183
EIF5	-0.019178
WARS	-0.019175
ACTN4	-0.019169
PPDPF	-0.019128
AMIGO2	0.018989
FOSL1	-0.018954
CALU	-0.018906
AP1S2	0.018876
TMEM30A	0.018870
S100A6	-0.018869
TIMP2	0.018810
SDCBP	0.018693
CEP55	-0.018650
RPS29	-0.018624
C14orf166	-0.018613
TRMT5	-0.018611
HIST1H2BD	0.018611
NHP2	-0.018572
SAT1	0.018554
SNRPF	-0.018496
UBL5	0.018474
UBA52	-0.018437
NDUFA11	0.018411
DEK	-0.018381
RPS6	0.018337
ACTR10	0.018307
GNB2L1	-0.018287
RPSA	-0.018263
RRM2B	0.018263
KCTD9	0.018203
ANXA4	0.018199
PABPC4	-0.018126
ABCC4	0.018126
CHP1	0.018116
BLOC1S2	0.017998
SUCLA2	0.017868
OAT	0.017813
CYFIP1	0.017758
CTHRC1	-0.017750
SNX3	0.017747
ZWINT	-0.017629
CDCA8	-0.017611
AURKA	-0.017561
TGFBR2	0.017552
COL15A1	-0.017546
FAM83D	-0.017545
TRIP13	-0.017483
CDCA3	-0.017452
ZMPSTE24	0.017393
TALDO1	0.017363
NUSAP1	-0.017349
PAM	0.017325
HTRA1	-0.017318
MELK	-0.017263
FGL2	-0.017224
COL5A1	-0.017093
SCOC	0.017070
TSLP	0.017031
COL4A1	-0.016985
SKP1	0.016959
F3	0.016928
XPOT	-0.016919
EIF4A2	0.016910
RPL10	-0.016807
WFDC1	0.016790
CNTN3	0.016759
SDC4	-0.016655
LAMTOR5	0.016625
TCEAL4	0.016624
MAP1LC3B	0.016611
PPIB	0.016602
SARAF	0.016556
CALR	-0.016539
EMP3	0.016536
CBX1	-0.016524
COPB2	0.016460
RPL41	0.016443
RBM24	0.016436
ZYX	-0.016377
H2BFS	0.016372
ZMAT3	0.016370
KPNB1	-0.016362
CD99	0.016361
VAT1	0.016334
PLAUR	-0.016296
TOMM5	-0.016269
SEC61G	-0.016239
MMADHC	0.016195
FAM46C	0.016144
RPS7	-0.016141
BUB3	-0.016133
RPS25	-0.016114
TOB1	0.016110
PRDX4	0.016086
RAP1B	-0.016078
ECI2	-0.016076
SMC4	-0.016018
GLRX	-0.016005
MYLK	0.015932
GMNN	-0.015909
FST	-0.015868
YWHAQ	0.015856
SPPL2A	0.015802
RRM1	-0.015766
DPYSL2	-0.015724
FAM162A	-0.015709
MLLT11	0.015685
YPEL5	0.015677
PCBP1	-0.015629
RPS4X	-0.015573
HLA-C	0.015554
GBP1	0.015536
PSAP	0.015500
AARS	-0.015468
SNRPD1	-0.015463
BUB1B	-0.015417
NUPR1	-0.015366
LYPD1	0.015341
DYNLRB1	0.015328
ATP5J2	0.015277
RPF2	-0.015252
SERINC3	0.015239
ACTA2	0.015169
RAC1	-0.015138
SURF4	-0.015121
NME1	-0.015075
PKD1P1	-0.015052
PPP2CB	0.015040