!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	VX
!smiles	CCOP(=O)(C)SCCN(C(C)C)C(C)C
!pubchem_cid	39793
!cell_type	hNHEPS hepatocytes exposed to 10μM
!organism	human
!end_metadata
ANKRD1	-0.102697
PTX3	-0.095508
CYP7A1	0.087142
INSC	-0.085383
ANXA3	-0.080599
CYP26A1	-0.079517
GPR34	-0.063123
GPRC5A	-0.063100
CXCL6	-0.059919
RNASE6	-0.059142
ADORA3	-0.055539
CYR61	-0.054536
IFI44L	-0.053699
ADAMDEC1	-0.053498
GPR65	-0.051761
IL18	-0.051258
NTN4	-0.050678
KCTD12	-0.048172
MS4A4A	-0.048136
PLA2G7	-0.047596
CYP1A1	0.046738
VSIG4	-0.045999
CCR1	-0.045650
GLIPR1	-0.044340
C1orf162	-0.044257
IP6K3	-0.043852
AMOTL2	-0.043607
ID1	-0.043591
PLK2	-0.043276
PMAIP1	-0.042586
FPR3	-0.042425
CRP	0.042175
OXTR	-0.041574
C1QB	-0.040913
HCLS1	-0.040723
ANGPTL4	-0.040305
GPR128	0.040202
PLAT	-0.039809
MPEG1	-0.039774
BASP1	-0.039700
CPS1-IT1	0.039588
C3AR1	-0.038444
FOXA3	0.038289
FSTL3	-0.038280
CAV1	-0.038149
ELF3	-0.038127
MS4A7	-0.038053
CYP1B1	0.037991
ZNF385B	0.037794
COTL1	-0.037125
TYROBP	-0.036970
SLC16A14	0.036693
HLA-DMB	-0.036669
LRRC19	0.036570
CD163	-0.036549
HLA-DRA	-0.036539
SLC7A7	-0.036371
C1QC	-0.036310
MS4A6A	-0.036231
MNDA	-0.036216
MRC1	-0.036101
ENC1	-0.035945
AKAP12	-0.035771
TGFB2	-0.035672
BMP2	-0.035642
GPR146	0.035397
CECR1	-0.035277
VEGFC	-0.035109
CCL20	-0.034988
FGL2	-0.034792
G6PC	0.034747
SLC17A1	0.034637
CCL2	-0.034635
BCL2A1	-0.034564
KRT80	-0.034405
RNF148	0.034361
LY86	-0.034267
FABP4	-0.033915
FBXO16	0.033780
GLIS3	-0.033550
S100A2	-0.033497
EVI2B	-0.033407
LXN	-0.033380
ITGA3	-0.033376
LAPTM5	-0.033239
ACE2	-0.033226
CRIM1	-0.033172
GPNMB	-0.033026
N4BP2	0.032996
RAPGEF4	0.032983
DUSP5	-0.032758
CYP4F11	0.032740
IL7R	-0.032623
PTGER2	-0.032499
FILIP1L	-0.032407
ADH1A	0.032256
NABP1	-0.032247
LOC145837	0.032050
CREB5	-0.031869
FCER1G	-0.031495
MMP9	-0.031439
C3orf33	0.031306
IFI16	-0.031289
SKIDA1	0.031273
GRAMD1C	0.031185
GEM	-0.031165
KCNJ8	0.031099
CXCL1	-0.030938
LYZ	-0.030571
ASAP2	-0.030527
TPM4	-0.030418
DKK1	-0.030412
HLA-DPB1	-0.030411
SNAPC1	-0.030401
TUFT1	-0.030399
C1QA	-0.030168
SLA	-0.030044
ACP5	-0.030036
BTBD11	-0.029969
ZNF680	0.029893
STK39	-0.029843
AXL	-0.029791
LOC101928505	-0.029679
ARHGAP15	-0.029549
STAT4	-0.029477
ID3	-0.029422
LMCD1	-0.029304
FCGR2B	-0.029301
SLC6A1	0.029244
LONRF2	0.029198
PRSS23	-0.029147
GPX8	-0.029090
GPER1	0.029011
NUCB2	0.028656
PROSER2	-0.028541
DAB2	-0.028515
TRIP13	-0.028420
EVI2A	-0.028405
NEXN	-0.028393
ARHGAP18	-0.028259
THBS1	-0.028156
CEACAM6	-0.028073
CCL18	-0.028018
THBD	-0.027905
PTPN14	-0.027886
TNFSF10	0.027804
MITF	-0.027761
ABHD15	0.027740
C12orf75	-0.027681
FABP5	-0.027650
FMNL2	-0.027608
CD52	-0.027607
HS3ST2	-0.027605
BICC1	-0.027584
IER3	-0.027488
LBH	-0.027379
OLFML2B	-0.027364
IL10RA	-0.027341
LIME1	0.027284
MATN2	-0.027262
TXNIP	-0.027145
S100A4	-0.027094
PPL	-0.027063
UGCG	-0.026766
TMEM51	-0.026761
TGFB1I1	-0.026704
SFN	-0.026691
DHRS9	-0.026663
TAGLN	-0.026648
GADD45G	0.026643
FLNA	-0.026635
SEMA3C	-0.026602
RNASE1	-0.026596
FLNB	-0.026563
TMED6	0.026529
FBLN5	-0.026527
LAMC2	-0.026495
MUM1L1	-0.026445
FGR	-0.026339
THBS2	-0.026310
CHST9	-0.026265
IFI27	-0.026217
EPSTI1	-0.026209
RDH12	0.026199
PTRF	-0.026164
SRGN	-0.026130
HCK	-0.026107
TTC30B	0.026058
VSIG10L	-0.026046
RRAS2	-0.025999
CCR6	0.025942
SLC38A3	0.025942
PLA2G4A	-0.025815
CCDC96	0.025786
TNFAIP8L1	0.025692
GIMAP6	-0.025681
C20orf194	-0.025622
BEX4	-0.025601
RCSD1	-0.025510
NPY6R	0.025477
IQGAP1	-0.025410
LOC100130232	0.025395
WISP1	-0.025375
CDA	-0.025337
COL4A1	-0.025255
DENND2C	0.025202
SLAIN1	0.025170
AMIGO2	-0.025152
SLC51A	0.025087
MIR21	-0.025086
FRMD3	-0.025011
SLFN11	-0.024997
GIMAP4	-0.024895
TLR5	-0.024843
LOC100507389	0.024693
C1orf116	-0.024656
PDIA4	0.024636
THAP5	0.024585
ZEB1-AS1	-0.024557
HAVCR1	-0.024515
S100P	0.024502
CYP2A6	-0.024494
MIR22HG	0.024462
AIF1	-0.024405
THRSP	0.024395
TMEM158	-0.024385
FAM134B	-0.024356
PEA15	-0.024253
CLGN	0.024204
NCKAP1L	-0.024195
TM6SF1	-0.024184
MYOT	-0.024129
SIGLEC10	-0.024111
PTPRC	-0.024111
INHBA	-0.024107
DACT1	-0.024098
FHL2	-0.024058
VGLL3	-0.023963
SASH3	-0.023953
WEE1	-0.023949
MYOF	-0.023875
SDF2L1	0.023864
MARCKS	-0.023833
IGKV1OR2-108	-0.023798
HAMP	-0.023770
PRG4	0.023761
CTGF	-0.023755
EPHA2	-0.023718
HLA-DRB1	-0.023714
RASSF2	-0.023675
LOC727916	0.023665
IGSF6	-0.023582
CSF2RB	-0.023498
IRS2	-0.023486
WFS1	0.023472
FLRT3	-0.023461
F13B	0.023445
HLA-DPA1	-0.023380
DEPDC1	-0.023352
MARCO	-0.023342
PGLYRP2	0.023318
KRT81	-0.023314
HSPB8	-0.023277
UCP2	-0.023266
UGT3A1	0.023203
ANLN	-0.023159
EPB41L3	-0.023158
CNGA1	0.023129
SALL1	0.023107
UBASH3B	-0.023094
CUX2	-0.023053
SPNS2	-0.023024
MYADM	-0.023023
C8B	0.022982
C11orf96	-0.022972
CYP4F3	0.022971
TFPI2	-0.022931
C8G	0.022920
SAMSN1	-0.022874
UGT2B17	0.022870
ZNF682	0.022860
VSTM2L	-0.022846
ANGPTL3	0.022742
TFEC	-0.022738
ZNF652	0.022716
TIMP2	-0.022691
ZNF432	0.022640
BEX5	0.022610
SLC10A1	-0.022596
GBP1	-0.022559
CDKN2B	-0.022510
KIF15	-0.022509
TMEM117	0.022481
CPVL	-0.022481
CRNDE	0.022467
SOX4	-0.022461
PDIA3	0.022454
NCF2	-0.022419
HK1	-0.022411
HMMR	-0.022408
DGKH	-0.022392
C8orf48	0.022367
RHBDF2	-0.022322
CNRIP1	-0.022308
C5AR1	-0.022292
LOC101928858	0.022215
HRG	0.022194
OLFML3	-0.022153
GJA1	-0.022147
WNT5A	0.022123
ITGA5	-0.022105
SLAMF8	-0.022050
GAS2	0.022032
RBM43	0.022030
LRRC31	0.022013
NR3C2	0.022009
DMGDH	0.021944
ANKS4B	0.021934
TSPAN5	-0.021870
EDN1	-0.021856
SGK223	-0.021839
CLEC10A	-0.021823
MMP12	-0.021820
SLC27A3	0.021796
CYP1A2	0.021776
ITGA2	-0.021768
TSPAN12	0.021742
BTBD3	0.021709
ADORA2A-AS1	0.021707
CNNM2	0.021680
TUBA1A	-0.021678
KIAA0907	0.021670
EMP3	-0.021618
HPCAL1	-0.021596
MAFF	-0.021592
SLC16A10	0.021579
CPED1	-0.021525
ND6	0.021522
SHROOM2	0.021503
ENTPD7	0.021483
B3GNT5	-0.021440
TMEM170B	0.021431
CD300LF	-0.021427
MAFB	-0.021422
PON1	0.021421
ZBTB21	-0.021413
OSBPL3	-0.021402
MPP6	0.021358
FGF19	-0.021339
ERO1LB	0.021328
ARRDC4	0.021327
NID2	-0.021320
PALM3	0.021277
PAIP2B	0.021265
PDGFC	-0.021250
IGF2BP2	-0.021173
IGLV1-36	-0.021169
GALNT15	-0.021162
MX1	-0.021119
SEC11C	0.021107
GNMT	0.021043
MMP1	-0.021030
LHFPL2	-0.021028
C3orf52	-0.021024
CXCR4	-0.021021
RAB7B	0.020991
RNASE2	-0.020951
GAL3ST1	0.020885
GIPC2	0.020859
CD8A	-0.020848
SIGLEC1	-0.020816
CEP55	-0.020730
C15orf52	-0.020729
FSTL1	-0.020728
EOGT	0.020723
SPARC	-0.020722
KIF21B	-0.020703
HAS2	-0.020700
SLC16A6	-0.020688
ADM	-0.020687
ARHGDIB	-0.020680
CXCL8	-0.020587
ALPK2	-0.020581
OAS2	-0.020574
HEY2	0.020562
LINC00543	0.020547
GPR183	-0.020544
LGALS1	-0.020507
RELN	0.020473
ZBED8	0.020458
HIST1H2BC	0.020430
CRELD2	0.020408
ETS1	-0.020392
FAM60A	-0.020377
PPP1R13L	-0.020351
CTSK	-0.020311
MYPOP	0.020276
TTPA	0.020251
KRTAP2-3	-0.020230
ITGB2	-0.020217
DNAJC28	0.020194
HSPBAP1	-0.020191
C16orf87	0.020177
CCR5	-0.020154
HIST1H3A	0.020149
LY96	-0.020130
CA2	0.020127
CABYR	0.020096
HAS3	-0.020084
CTHRC1	-0.020059
SMAD3	-0.020053
FAM101B	-0.020014
RARRES3	0.020010
ARHGEF3	-0.020007
PIK3R1	0.019986
ADAP2	-0.019953
ARSJ	-0.019951
SOCS2	-0.019949
APOF	0.019935
CD84	-0.019932
CPN1	0.019932
ERICH5	-0.019926
FAM169A	0.019918
LPCAT1	-0.019905
TIMP3	-0.019897
TNFRSF21	-0.019889
IL33	-0.019881
DPCR1	-0.019858
CLRN3	0.019854
BIRC3	-0.019836
CSF1R	-0.019821
MLKL	-0.019798
VSNL1	0.019750
F3	-0.019718
OSGIN1	0.019687
C11orf52	0.019648
IRF9	-0.019647
OLFML1	0.019633
C1orf53	0.019622
MSR1	-0.019617
COL5A2	-0.019615
PPAPDC1B	0.019592
SERPINA7	0.019584
AFP	0.019583
HSPA6	-0.019564
PAM	-0.019470
PLA2G12B	0.019464
ABHD13	0.019461
SERPING1	0.019413
IGJ	-0.019376
LOC154761	0.019372
LOC100996579	0.019342
RAB31	-0.019325
HYOU1	0.019325
GPR88	0.019315
XK	0.019301
ATP6V0E2	0.019299
PGBD3	0.019295
SERPINE1	-0.019281
G0S2	-0.019263
AFM	0.019261
CHIC2	-0.019232
LILRB5	-0.019195
ZNF275	0.019194
LOC101927027	-0.019178
TLR8	-0.019175
CDC20	-0.019148
HIST2H2BE	0.019130
GIMAP7	-0.019120
RAB8B	-0.019111
PPP1R14A	-0.019077
NRTN	0.019072
EMP1	-0.019056
RUSC2	-0.019044
TUBB6	-0.019024
ARL4C	-0.019003
GPRC5B	-0.018996
RGL1	-0.018990
GFPT1	0.018954
PAQR9	0.018941
ELAC1	0.018932
NR4A2	0.018930
ARHGEF26	0.018887
PLXDC2	-0.018882
SPSB1	-0.018882
LOC400099	0.018878
SPINT2	-0.018871
EXOC1	-0.018849
RRAD	-0.018830
MFI2	-0.018813
RSAD2	-0.018808
NUP160	0.018768
NETO2	-0.018762
UBL7-AS1	0.018716
FRMD6	-0.018715
IFIT1	-0.018681
LOC100287896	0.018679
SOWAHA	0.018670
APOBEC3B	-0.018664
CXCL3	-0.018659