!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!ligand_name	estradiol
!ligand_id	CHEBI:23965
!cell_type	estrogen receptor (ER)-positive MCF7 breast cancer cells
!organism	human
!end_metadata
SLC7A5	0.153516
ID1	-0.140215
LXN	-0.134362
TPD52L1	0.131264
DKK1	-0.129484
BAMBI	-0.118912
MIR21	-0.118435
BASP1	-0.117620
SLC9A3R1	0.113563
PLEKHF2	-0.093597
FTH1	-0.087677
CD24	-0.087000
COX1	-0.083130
RAN	0.081626
DHRS2	0.081104
GATA3	-0.080582
HSPA8	0.080522
DDIT4	-0.079939
SIAH2	0.079411
HSPB8	0.079182
SLC26A2	0.078216
NPY1R	0.076442
SNRPF	0.076317
NHP2	0.075829
PTP4A1	0.075253
RRM2	0.074371
IARS	0.073818
RPS18	-0.070990
PPT1	-0.070863
IRF2BPL	-0.070157
PKIB	0.069564
RPL22L1	0.068264
BCAS3	-0.067290
PNRC1	-0.067177
S100A7	0.067098
NME1	0.065827
ETFA	-0.064761
MRPL3	0.064429
FAM84B	-0.064389
TMSB10	-0.064178
PPIF	0.063569
SNRPD3	0.063420
IGFBP4	0.060077
DDX21	0.059284
MRPL36	0.058773
KRT19	0.058176
PCNA	0.056700
ARPC3	0.055644
EMG1	0.054832
BLVRB	0.054083
RAB31	0.054059
C1QBP	0.053296
NOP58	0.053012
CCT2	0.053001
PHB2	0.052986
FBL	0.052724
KYNU	-0.051702
COX2	-0.050256
COX7A2	-0.049762
PPIB	0.049734
XBP1	0.049481
ID2	-0.049419
CA12	0.048499
TMEM64	0.048447
ACTG1	-0.048195
TSKU	0.047964
RPS29	-0.047433
KRT18	-0.047361
CELSR2	0.047023
HNRNPAB	0.046984
NCOA3	-0.046895
ID3	-0.046730
STARD10	0.046718
UBE2S	0.046653
DYNLT3	0.046554
PSME2	-0.046498
UBC	-0.046393
SLIRP	0.046343
PIK3R3	-0.046174
CD63	-0.046063
FTH1P5	-0.045885
SYTL2	-0.045824
HIF1A	0.045741
TMEM150C	-0.045321
MRPS23	0.045309
ARMCX6	0.044851
UBE2T	0.044635
ND2	-0.044530
ATP1B1	-0.044508
BRIP1	0.044417
ZNF217	-0.044214
SLC3A2	0.044086
GREB1	0.043971
TUBB4B	0.043775
GLA	0.043767
DCTPP1	0.043537
RPS10	-0.043376
RPL36A	-0.043277
C20orf24	0.043194
ERH	0.043175
TUBB	0.042885
EIF4A1	0.042493
PTRH2	0.042289
NQO1	-0.042171
CCNG1	-0.042135
CXXC5	0.041682
MYEOV2	0.041616
MSMO1	0.041110
ACTB	-0.040949
TPT1	-0.040645
FDFT1	0.040534
S100P	-0.040379
MYO1B	-0.040259
TMA7	-0.040160
TUBA1C	-0.039421
GABARAPL2	-0.039279
HSPE1	0.039215
TPBG	0.039197
MRPL15	0.039054
NFKBIA	-0.039006
MAPK6	0.038957
IER3	0.038920
PRMT6	0.038838
KARS	0.038223
RPS3A	-0.038148
CMC2	0.037855
FKBP4	0.037836
MREG	0.037741
IFITM3	-0.037430
CERS2	-0.037317
OSBPL9	-0.037108
CLU	-0.037017
UHRF1	0.037006
LOC100129361	-0.036982
CTSD	0.036982
IMP4	0.036809
SYTL5	0.036742
LYSMD2	0.036716
RRS1	0.036359
HILPDA	-0.036318
NRIP1	0.036213
REEP5	-0.036200
EPCAM	-0.035741
DBI	-0.035383
CYCS	0.035197
NAA50	0.035137
YBX1	0.034987
PRMT1	0.034957
DSTN	-0.034870
AHSA1	0.034667
SLC12A2	-0.034436
DSP	-0.034341
HMGN2	-0.034333
FBP1	-0.034290
DPM1	0.034219
TRIM37	-0.034178
RPL31	-0.034128
ISCU	0.034093
IFIT1	-0.034055
GNG5	-0.033822
CS	0.033666
DNAJC1	-0.033572
SOD1	-0.033521
DNAJA1	0.033506
RBM24	0.033488
ZFP36L2	-0.033241
STIP1	0.033128
NCL	0.033069
ABAT	0.032839
RAD51C	0.032644
RPL12	-0.032631
DKC1	0.032590
SIDT1	-0.032544
PNPT1	0.032401
TBCA	0.032373
POLE3	0.032369
SMS	0.032206
CAPNS1	-0.032161
RPL30	-0.032084
BOLA3	0.032005
CBWD1	0.031914
GMNN	0.031840
VMP1	-0.031683
MAL2	-0.031646
CCND1	0.031558
HIST1H2BD	-0.031530
RPLP0	-0.031472
KPNA2	0.031424
EGR3	0.031419
RPL5	0.031078
SERPINA3	0.031044
LDHA	0.031044
TFRC	0.030879
MAD2L1	0.030867
CDK4	0.030823
MRPS34	0.030802
MCM2	0.030694
FOXA1	-0.030643
GSTM3	-0.030498
RPS2	-0.030394
TFAP2C	0.030368
ZDHHC7	-0.030366
GPR160	-0.030301
NARS	0.030286
RPL26	-0.030170
ADIPOR2	-0.030066
FAM102B	-0.029995
RPS5	0.029845
NPM1	0.029767
PAICS	0.029691
NOL11	0.029597
MYOF	0.029579
TSPAN13	-0.029524
RPF2	0.029418
ABCE1	0.029380
RPL27	0.029358
SMIM15	0.029333
DDX5	-0.029292
SLC35A1	-0.029201
RNPS1	0.029180
TXNIP	-0.028910
SHFM1	0.028803
LITAF	-0.028778
DDR1	-0.028775
COA4	0.028774
MIF	0.028748
C1orf43	0.028726
ATF4	-0.028671
PSAP	-0.028637
ATP5E	-0.028628
TUBB3	0.028424
FABP5	0.028365
ALYREF	0.028365
ENO1	-0.028355
SEC16A	-0.028344
STOM	-0.028287
YWHAG	0.028275
ODC1	0.028170
DHCR7	0.028130
UQCRFS1	0.028010
BTG1	-0.027856
RPL8	-0.027853
TOMM5	0.027775
TSTD1	-0.027772
TXNRD1	-0.027737
SAT1	-0.027699
HSPH1	0.027689
FTL	-0.027682
CIRH1A	0.027552
EEF1A1	-0.027496
RPS26	0.027478
NUP35	0.027444
EIF4B	-0.027378
STARD7	0.027374
C6orf211	-0.027310
RET	0.027244
ARL6IP1	-0.027195
CCT5	0.027181
SNHG5	-0.027139
IRF9	-0.027107
WSB2	-0.026949
MYO6	-0.026942
SNHG1	0.026911
NOLC1	0.026905
HSP90AB1	0.026899
SLC1A5	0.026847
PRR13	0.026642
ARNT2	-0.026523
VDAC2	0.026420
NDUFA4	-0.026371
LY6E	0.026294
TOB1	0.026276
NOP10	0.026249
UNG	0.026107
CCT3	0.026073
UBE2M	0.025976
UGDH	0.025937
C19orf48	0.025911
C9orf152	-0.025883
TMBIM6	-0.025772
RXRA	-0.025608
HIST1H2BH	-0.025577
PRELID1	0.025573
SNRPA1	0.025329
TPI1	0.025306
CNBP	0.025298
RPL39	-0.025296
MCM6	0.025245
SGCG	-0.025201
MRPL49	0.025076
PRKAR1A	-0.025070
DHCR24	-0.025029
CCT7	0.025020
NAA20	0.025020
TMEM59	-0.024980
EFNA1	-0.024939
SRSF2	0.024922
MRPL16	0.024878
FAM96A	0.024872
RBL2	-0.024793
SDCBP	-0.024758
RPS4X	-0.024700
CD99	-0.024695
PA2G4	0.024659
MLPH	-0.024657
NUP107	0.024640
CDH3	-0.024591
MYL12A	-0.024591
PFDN2	0.024498
MRPS30	0.024453
ILF2	0.024425
CEBPB	0.024401
TKT	0.024387
POLR2G	0.024341
ETF1	0.024270
C19orf33	0.024228
RPN2	-0.024197
EIF3D	0.024176
SMIM14	-0.024168
MRPL14	0.024142
PRC1	0.024103
TRMT10C	0.024087
SLC38A2	0.024087
ANP32B	0.024061
RFX5	-0.024004
CHCHD10	0.023954
SOCS2	-0.023887
ACSL3	-0.023804
EDF1	0.023779
CCDC47	0.023662
FEN1	0.023641
CCDC86	0.023616
CKS2	0.023584
MRPL18	0.023532
CDKN1B	-0.023530
PSMB5	0.023502
SRM	0.023455
HIST1H2AC	-0.023426
SET	0.023398
C12orf57	-0.023386
RUVBL1	0.023365
SF3B5	0.023360
KLHDC2	-0.023351
CYC1	0.023338
DYNLL1	0.023305
GPRC5A	-0.023298
TCERG1	0.023275
OAT	-0.023150
SERBP1	0.023141
MELK	0.023082
EIF6	0.023043
VIMP	0.023017
CACYBP	0.023010
B4GALT1	0.023009
EIF2S1	0.022999
AMD1	0.022966
HMGCS1	0.022920
PGR	0.022903
EEF1G	-0.022841
ADRM1	0.022828
PSMG1	0.022817
GAPDH	-0.022815
YIF1A	0.022770
EEF1B2	0.022702
PRSS23	0.022682
MCM7	0.022678
FAM162A	-0.022644
WDR3	0.022643
PABPC3	-0.022514
OSTC	0.022472
PHB	0.022450
MRFAP1	0.022445
H1F0	-0.022415
CIB1	-0.022380
GRB14	-0.022377
NDUFS2	-0.022374
HSP90AA1	0.022310
GBAS	-0.022277
ADIRF	-0.022264
NDUFAB1	0.022171
GTPBP4	0.022161
TMEM14A	-0.022151
BRI3BP	0.022149
PPL	-0.022132
SLC19A2	0.022124
PTDSS1	0.022117
GYG1	-0.022005
HADHB	-0.021941
LINC00493	-0.021925
MARCKSL1	0.021884
ASS1	0.021805
PPP3CA	-0.021784
GNB2L1	-0.021784
CTPS1	0.021775
CCNG2	-0.021768
SGK3	0.021714
RPS25	-0.021646
SSB	0.021622
HERPUD1	-0.021595
SERF2	-0.021552
GNAS	-0.021520
SLC2A10	-0.021487
SERINC3	-0.021459
RPL28	-0.021454
CALM1	0.021416
SYAP1	0.021367
GEMIN5	0.021359
COMT	-0.021295
HPRT1	0.021259
SEMA3C	0.021162
LRP11	-0.021085
SNRPD2	0.021080
POLD2	0.021066
PPP1R3C	-0.020980
SF3B4	0.020915
RPL35	-0.020888
NTN4	-0.020887
PTMA	0.020887
RNASEH2A	0.020836
ADAR	-0.020803
COX4I1	-0.020774
MYL6	-0.020766
APRT	0.020711
RPL23A	-0.020645
S100A10	-0.020645
ACTR3	-0.020643
SRSF1	0.020643
CSTA	-0.020612
EIF3G	0.020545
EIF2S3	0.020521
WDR12	0.020493
CMSS1	0.020480
EIF3J	0.020470
HSPA1A	0.020461
CKS1B	0.020442
LOC93622	0.020411
KLF10	0.020337
PSME1	-0.020304
SPPL2A	-0.020284
MRPL22	0.020277
UTP18	0.020235
RPL36AL	0.020211
CCT6A	0.020204
SLC25A1	0.020190
TMX1	0.020169
GLRX5	0.020097
NELFCD	0.020089
GPD1L	-0.020080
GLRX2	0.020019
PRMT5	0.020000
RPL37A	-0.019988
NOP56	0.019958
NME7	-0.019940
IFRD2	0.019933
UBP1	-0.019922
PSMD12	0.019890
VDAC1	0.019874
RPL13	0.019853
TOMM40	0.019845
SLC25A39	0.019788
UBA1	-0.019780
NXT1	0.019779
NAE1	0.019775
PRPF19	0.019706
CD47	0.019694
TPRKB	0.019647
YPEL5	-0.019625
JUP	-0.019593
NDUFA1	-0.019583
GGCT	0.019583
B2M	-0.019447
SFN	0.019419
FAM107B	-0.019408
DTX3L	-0.019395
S100A11	-0.019394
HEBP1	-0.019371
C17orf58	-0.019361
SRSF7	0.019359
EIF4A3	0.019329
SURF1	0.019329
S1PR3	-0.019320
ARPC5L	0.019288
CD164	-0.019263
LMBR1	0.019254
BYSL	0.019250
ISG15	-0.019219
RPSA	-0.019206
PPP1CC	0.019199
SF3B6	0.019194
CDC123	0.019184
LSM1	0.019151
ABHD17C	-0.019136
SLC25A32	0.019113
SEPP1	-0.019112
DNAJB11	0.019111
ZMPSTE24	0.019104
ATP5J	0.019092
ZNF706	0.019061
ADM	-0.019043
CREB3L4	-0.019028