!direction	0
!num_genes	500
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!ligand_name	estrogen
!ligand_id	CHEBI:50114
!cell_type	MCF-7 cells
!organism	human
!end_metadata
AGR3	0.081798
KLK11	0.070415
PKIB	0.068199
SGK1	0.062215
ATAD2	0.058615
CENPK	0.058468
DTL	0.058333
PSCA	-0.056896
CCNE2	0.054997
CDC6	0.053872
ZNF367	0.053749
NPY1R	0.049160
BRIP1	0.049092
CXCL12	0.048305
SFXN2	0.048073
HCK	0.047514
RAMP3	0.047238
RLN2	0.046141
PCNA	0.045347
MCM10	0.045200
SGK3	0.045197
CA2	0.044687
UHRF1	0.044505
RERG	0.044129
CYP1A1	-0.043752
PLOD2	0.043095
E2F8	0.042506
RNASE4	-0.042041
GMNN	0.041492
CDC45	0.041425
MASTL	0.041133
DONSON	0.041088
SHCBP1	0.040808
TIPIN	0.040734
RRM2	0.040488
ANLN	0.040488
LMBR1	0.040131
RAB31	0.039370
FBXO5	0.038731
MND1	0.038257
SPIN4	0.038079
ALDH1A3	-0.038078
RAD51AP1	0.037874
RFC4	0.037845
FABP5	0.037641
GLA	0.037375
MCM4	0.037060
PGR	0.037017
SKA1	0.036246
NUF2	0.036001
CENPH	0.035876
NCAPG2	0.035326
ARHGAP36	0.035233
PPIF	0.035177
DHRS3	-0.034882
LMNB1	0.034785
GRHL3	-0.034621
MAD2L1	0.034505
TFF1	0.034341
CEP55	0.034310
POC1B	0.034289
HEY2	0.034067
GREB1	0.033761
PBK	0.033699
FIGNL1	0.033679
RAB26	-0.033586
CDC7	0.033427
SPC25	0.033244
ORC1	0.033096
ELOVL2	0.033010
PMAIP1	0.032936
AMD1	0.032723
KIAA0226L	0.032582
HSP90AA1	0.032542
MGP	0.032530
TMEM164	0.032415
B3GALNT1	0.032193
GINS1	0.032152
RFWD3	0.031887
FREM2	0.031854
SLC39A6	0.031836
NUP155	0.031760
SLC6A14	0.031758
MDM1	0.031563
NDC80	0.031413
HSPH1	0.031213
CHRNA5	0.031200
HAUS1	0.031189
ASF1B	0.030970
GALNT4	0.030803
PP14571	-0.030689
UNG	0.030686
MCM2	0.030587
OIP5	0.030576
ABCE1	0.030568
CHAC2	0.030484
EP300-AS1	0.030316
RET	0.030220
POLE2	0.030153
WFDC21P	-0.030107
LOC653602	-0.030031
RFC2	0.030016
SLC31A2	-0.029986
KIAA0101	0.029954
CTPS1	0.029938
ABHD2	0.029928
MCM3	0.029864
MELK	0.029832
AHRR	-0.029734
FEN1	0.029680
PRIM1	0.029599
DBF4	0.029540
NRIP1	0.029498
C6orf141	0.029424
IGFBP3	-0.029386
TTK	0.029344
SLBP	0.029184
HSPA4L	0.029117
NCAPG	0.029087
ANP32E	0.029077
BUB1B	0.028898
EGLN3	-0.028832
EZH2	0.028724
SYTL4	0.028702
UBE2T	0.028603
SYBU	0.028570
ORC6	0.028437
RRM1	0.028406
HELLS	0.028394
MCM7	0.028344
PDZK1	0.028324
TPD52L1	0.028224
MSH2	0.028186
DDIT4	-0.028104
VRK1	0.028085
CSE1L	0.028075
NTN4	-0.028061
TOPBP1	0.027988
MCM6	0.027860
ZWILCH	0.027856
CCNA2	0.027841
CDK1	0.027719
FHL1	0.027643
CA12	0.027639
UPK1A	-0.027621
SMIM5	-0.027536
MALAT1	-0.027463
KIF11	0.027424
FANCI	0.027354
ANG	-0.027340
TMEM140	-0.027256
STIL	0.027248
RFC3	0.027234
PAICS	0.027145
DNMT1	0.027134
E2F7	0.027123
TIFA	0.027094
C1orf226	0.027060
GFRA1	0.027020
DCK	0.027014
CDCA5	0.026979
MYBL2	0.026951
MYB	0.026931
RMI1	0.026916
ACTL6A	0.026908
BIK	-0.026888
RMI2	0.026725
ST3GAL1	-0.026616
MCM5	0.026615
SAT2	-0.026602
SELL	-0.026493
CDT1	0.026441
TMEM64	0.026415
TRIP13	0.026387
MALL	-0.026280
MREG	0.026261
ABCB10	0.026146
KRT80	-0.026044
CDCA7	0.025882
HS3ST3A1	0.025850
IL1R1	-0.025818
SEMA3C	0.025800
C4orf46	0.025796
NDRG1	-0.025771
TCF19	0.025686
TIMM21	0.025644
NECAB1	0.025605
TOP2A	0.025562
FKBP5	0.025546
MTHFD1	0.025537
NCAPH	0.025515
SUPT16H	0.025394
OTUD6B	0.025348
HMCN1	0.025263
PUS7	0.025249
HILPDA	-0.025204
NUP107	0.025194
ASB9	-0.025150
POLA1	0.025112
GINS3	0.025055
BEX4	-0.025047
IGSF1	0.024959
SMC2	0.024902
AGR2	0.024865
DEK	0.024729
GABBR2	-0.024603
USP1	0.024458
UBA2	0.024371
BRI3BP	0.024302
GPN3	0.024289
STC2	0.024201
DSN1	0.024151
PRSS23	0.024128
AREG	0.024120
CMSS1	0.024050
SLC35E2	-0.023931
SOX3	0.023924
NOP58	0.023904
CAP2	0.023875
RIBC2	0.023781
IGFBP4	0.023775
SLC1A1	0.023734
RB1	0.023546
PPL	-0.023532
RECQL	0.023532
NAA50	0.023517
HIF1A	0.023511
PRC1	0.023491
TMPO	0.023485
DDX21	0.023477
CCT2	0.023377
ITGB3BP	0.023377
RACGAP1	0.023364
TMEM194A	0.023363
NCEH1	0.023338
PRR15	-0.023336
BMF	-0.023330
PRPS2	0.023315
C2orf69	0.023294
KLHL13	0.023277
CDH26	0.023245
SOX9	-0.023236
ZNF600	0.023161
HNRNPH3	0.023158
DHFR	0.023113
GOLT1A	-0.023093
S100P	-0.023058
E2F1	0.023046
DLGAP5	0.023036
TMPO-AS1	0.022940
HIST1H4C	0.022913
C1orf106	-0.022884
PLA2G10	-0.022875
TK1	0.022860
TTF2	0.022849
BLNK	-0.022715
NDC1	0.022708
TUBG1	0.022702
SKP2	0.022698
EIF1AX	0.022632
ABCA12	0.022618
TMEM40	-0.022614
THAP9-AS1	0.022586
HAT1	0.022581
MSMB	0.022569
MXD4	-0.022523
PCP4	0.022495
HSPE1	0.022485
RBBP8	0.022475
EFNA1	-0.022411
TP53INP2	-0.022395
ZNF267	0.022381
VTCN1	-0.022342
RAB5C	-0.022342
NETO2	0.022324
FANCL	0.022297
PIFO	-0.022289
HSPA8	0.022287
UPK3A	-0.022199
DNAJC9	0.022165
CRIP1	-0.022132
SAT1	-0.022078
PAK1IP1	0.021991
EXOSC9	0.021983
RPA3OS	0.021975
HLTF	0.021958
LOC285074	-0.021937
ID1	-0.021920
KCTD3	0.021882
TCF7L1	-0.021875
PPM1K	0.021855
MVP	-0.021850
LYPD1	-0.021842
NOLC1	0.021841
SYTL5	0.021831
NUP35	0.021827
OSCP1	-0.021756
ANXA3	-0.021749
RFC5	0.021745
RGAG4	-0.021745
IFIT1	-0.021714
TOM1	-0.021704
PRSS8	-0.021677
JSRP1	-0.021625
POLD1	0.021601
TNFRSF21	-0.021538
LOC100506870	0.021523
MB	-0.021518
SERHL2	-0.021454
SSFA2	0.021447
KDM1B	0.021427
FAM174B	-0.021424
C9orf40	0.021361
CYSRT1	-0.021298
LYPD3	-0.021294
MRPL1	0.021285
CYP4B1	-0.021238
CHUK	0.021232
LRP10	-0.021229
UGT2B15	0.021226
FAM83E	-0.021197
OAS1	-0.021184
BRCA1	0.021174
CGN	-0.021156
PIGW	0.021133
SIGLEC15	0.021099
PARP12	-0.021094
LINC01137	-0.021077
CDCA7L	0.021070
RHNO1	0.021051
LDHA	0.021025
TTI1	0.021018
NUP160	0.021001
CEP76	0.020990
ELF3	-0.020969
MICB	0.020958
NEBL-AS1	-0.020955
RTN2	-0.020934
KIF21A	0.020881
ZWINT	0.020837
MARCH2	-0.020836
NMD3	0.020824
LRRC73	-0.020809
CLDN9	-0.020779
NCBP1	0.020770
DHX9	0.020714
GCLM	0.020621
ZNF296	-0.020602
SSR3	0.020601
SCN1B	-0.020571
DNAJA1	0.020557
TMC4	-0.020516
NKX3-2	-0.020498
RND1	-0.020498
RIPK4	-0.020459
CENPQ	0.020458
SUCLA2	0.020458
HAUS3	0.020432
SIL1	-0.020400
QSER1	0.020390
WISP2	0.020378
CDC25A	0.020364
C14orf142	0.020356
ANKRD35	-0.020352
UPK3B	-0.020323
EXOSC8	0.020305
RNASEH2A	0.020284
USP37	0.020281
TEX30	0.020280
ZDHHC7	-0.020244
RAD51C	0.020227
TBPL1	0.020160
SHISA2	-0.020160
CENPU	0.020157
NYNRIN	-0.020149
WRB	0.020137
AQP3	-0.020120
CBX6	-0.020111
OR6A2	0.020099
CDCA4	0.020077
EIF5B	0.020063
CBX5	0.020029
HMGB1	0.020004
UBE2L6	-0.019970
XPOT	0.019959
ISOC1	0.019951
EGR3	0.019937
BPIFB1	-0.019899
CTR9	0.019884
CHEK2	0.019882
NOC3L	0.019824
SUV39H2	0.019821
PFKFB3	-0.019813
TXNDC16	0.019800
RRN3	0.019790
KRT81	-0.019785
SPRY1	-0.019782
RAPGEFL1	0.019776
SEH1L	0.019750
BRI3	-0.019738
PARP2	0.019702
RBBP5	0.019683
WDR13	-0.019674
HSPA2	0.019671
CENPW	0.019646
BRCC3	0.019635
MIR22HG	-0.019617
C6orf211	0.019593
TFPI2	0.019590
SPAG1	0.019545
TYMS	0.019535
REG4	-0.019530
ORC3	0.019503
SLC26A2	0.019491
GEMIN5	0.019481
CPSF3	0.019422
HCAR3	-0.019415
IFI35	-0.019414
PINK1	-0.019413
DHX15	0.019403
BTG2	-0.019377
MIS18A	0.019347
ATF1	0.019343
DDIAS	0.019332
HES1	-0.019319
VAMP5	-0.019315
CTNNAL1	0.019270
DLAT	0.019270
CCDC64B	-0.019220
FAM65C	-0.019215
CBLN3	-0.019215
APPL1	0.019206
TMOD3	0.019180
TMEM45B	-0.019156
RGS22	0.019123
IL17RB	0.019101
REEP1	0.019099
DERA	0.019090
MKI67	0.019080
AHSA1	0.019068
SPSB2	-0.019067
RNF138	0.019066
SNX10	0.019062
MID1IP1	-0.019024
CENPM	0.018996
ORAI3	-0.018963
FAM84A	-0.018923
NXT2	0.018921
TTC30A	0.018916
NOL8	0.018905
C12orf75	0.018902
CALCR	0.018896
LYAR	0.018880
C2orf54	-0.018877
HDHD3	-0.018876
ERH	0.018868
PMEPA1	-0.018863
UCK2	0.018822
RILPL2	-0.018810
GBE1	0.018805
ZNF680	0.018801
LRIF1	0.018798
MYBL1	0.018786
CTGF	-0.018755
BAMBI	-0.018753
SPATA5	0.018748
PLEKHA7	-0.018738
SRSF10	0.018720
NEDD1	0.018719
ZDHHC6	0.018689
L1CAM	-0.018688
TIPARP	0.018682
PTK6	-0.018662
TAF1A	0.018633
CAPN5	-0.018624
RRM2B	0.018622
PHLDA3	-0.018583
LMO2	-0.018553
TTC37	0.018544
TGFBI	-0.018530
HSPG2	-0.018513
SFR1	0.018488
FAM216A	0.018483
TSPAN1	-0.018460
CMC2	0.018439
PPIL1	0.018423
SLC25A32	0.018404
CHEK1	0.018396
GINS2	0.018387
THAP10	0.018377
TECPR1	-0.018373
MARCKS	-0.018330
P2RX2	-0.018329
ATP13A3	0.018323
SRSF2	0.018320
YEATS4	0.018311
C10orf10	-0.018307
SLC9A3R1	0.018283
RASD1	-0.018280
GNL2	0.018250